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https://www.readbyqxmd.com/read/28090441/principal-component-analysis-t1%C3%AF-voxel-based-relaxometry-of-the-articular-cartilage-a-comparison-of-biochemical-patterns-in-osteoarthritis-and-anterior-cruciate-ligament-subjects
#1
Valentina Pedoia, Colin Russell, Allison Randolph, Xiaojuan Li, Sharmila Majumdar
BACKGROUND: Quantitative MR, including T1ρ mapping, has been extensively used to probe early biochemical changes in knee articular cartilage of subjects with osteoarthritis (OA) and others at risk for cartilage degeneration, such as those with anterior cruciate ligament (ACL) injury and reconstruction. However, limited studies have been performed aimed to assess the spatial location and patterns of T1ρ. In this study we used a novel voxel-based relaxometry (VBR) technique coupled with principal component analysis (PCA) to extract relevant features so as to describe regional patterns and to investigate their similarities and differences in T1ρ maps in subjects with OA and subjects six months after ACL reconstruction (ACLR)...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28078610/optimization-of-the-return-to-sport-paradigm-after-anterior-cruciate-ligament-reconstruction-a-critical-step-back-to-move-forward
#2
REVIEW
Bart Dingenen, Alli Gokeler
Athletes who have sustained an anterior cruciate ligament (ACL) injury often opt for an ACL reconstruction (ACLR) with the goal and expectation to resume sports. Unfortunately, the proportion of athletes successfully returning to sport is relatively low, while the rate of second ACL injury has been reported to exceed 20% after clearance to return to sport, especially within younger athletic populations. Despite the development of return-to-sport guidelines over recent years, there are still more questions than answers on the most optimal return-to-sport criteria after ACLR...
January 11, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28072630/bracing-of-the-reconstructed-and-osteoarthritic-knee-during-high-dynamic-load-tasks
#3
Harvi F Hart, Kay M Crossley, Natalie J Collins, David C Ackland
PURPOSE: Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics are frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee brace during high dynamic loading activities in individuals with lateral knee osteoarthritis after ACLR and valgus malalignment. METHODS: Nineteen participants who had undergone ACLR 5 to 20 years previously and had symptomatic and radiographic lateral knee osteoarthritis with valgus malalignment were assessed...
January 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28064350/a-descriptive-study-of-potential-effect-of-anterior-tibial-translation-femoral-tunnel-and-anterior-cruciate-ligament-graft-inclination-on-clinical-outcome-and-degenerative-changes
#4
Žiga Snoj, Oskar Zupanc, Klemen Stražar, Vladka Salapura
INTRODUCTION: There is no evidence that anatomically correct anterior cruciate ligament reconstruction (ACLR) offers lower rate of degenerative changes development or that it would lead to a better outcome. The significance and understanding of the abnormal anterior tibial translation (ATT) in ACLR patients is yet to be established. METHODS: Sixty subjects (40 patients at 5.9 years after ACLR, 20 healthy controls) underwent 3 T MRI. Quantitative cartilage T2 mapping and morphological whole organ magnetic resonance imaging score (WORMS) evaluation was performed...
January 7, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28039768/analysis-of-three-dimensional-knee-kinematics-during-stair-descent-two-decades-post-acl-rupture-data-revisited-using-statistical-parametric-mapping
#5
Gisela Sole, Todd Pataky, Eva Tengman, Charlotte Häger
Changes in movement patterns following knee injuries have generally used analyses of pre-defined discrete event-related variables, whereas Statistical Parametric Mapping (SPM) assesses continuous data over time. We applied SPM to test differences for knee trajectories during stair descent between participants with past anterior cruciate ligament (ACL) rupture who underwent reconstruction or only physical therapy compared to healthy controls. Three-dimensional knee joint kinematics during stair descent were registered for 31 subjects with ACL reconstruction (ACLR), 36 subjects with ACL rupture managed with physical therapy only (ACLPT) (∼23years post-injury), and 32 uninjured controls...
December 20, 2016: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28038341/standing-balance-and-inter-limb-balance-asymmetry-at-one-year-post-primary-anterior-cruciate-ligament-reconstruction-sex-differences-in-a-cohort-study-of-414-patients
#6
Ross A Clark, Stuart W Bell, Julian A Feller, Timothy S Whitehead, Kate E Webster
BACKGROUND: Static standing balance can be safely assessed early following anterior cruciate ligament reconstruction (ACLR), and deficits may have important implications for long-term outcomes. This study includes a large cohort of people post-ACLR and has the primary aim of establishing whether inter-limb and sex differences exist, with a secondary aim of assessing the association between static balance variables and other outcome measures. METHODS: A total of 414 patients with a primary ACLR performed a 30-s static single leg balance test...
December 16, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27992239/differential-effects-of-two-rehabilitation-programs-following-anterior-cruciate-ligament-reconstruction
#7
Igor Setuain, Mikel Izquierdo, Fernando Idoate, Eder Bikandi, Esteban M Gorostiaga, Per Aagaard, Eduardo L Cadore, Jesús Alfaro-Adrián
Context- The muscular function restoration related to the type of physical rehabilitation followed after anterior cruciate ligament reconstruction (ACLR) using autologous hamstring tendon graft in terms of strength and cross sectional area (CSA) remain controversial. Objective- To analyze the CSA and force output of quadriceps and hamstring muscles in subjects following either an Objective Criteria-Based rehabilitation (OCBR) algorithm or the usual care (UCR) for ACL rehabilitation in Spain, before and one year after undergoing an ACLR...
December 19, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27930453/whole-body-vibration-improves-early-rate-of-torque-development-in-individuals-with-acl-reconstruction
#8
Derek N Pamukoff, Brian Pietrosimone, Eric D Ryan, Dustin R Lee, Lee E Brown, J Troy Blackburn
The purpose of this study was to compare the effect of whole body vibration (WBV) and local muscle vibration (LMV) on early and late quadriceps rate of torque development (RTD), and electromechanical delay (EMD) in individuals with anterior cruciate ligament reconstruction (ACLR). 20 individuals with ACLR were recruited for this study. Participants performed isometric squats while being exposed to WBV, LMV, or no vibration (control) in a randomized order during separate visits. Quadriceps early and late quadriceps RTD, and EMD were assessed during a maximal voluntary isometric knee extension prior to and immediately following WBV, LMV, or control...
November 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27923626/limitations-in-predicting-outcome-following-primary-acl-reconstruction-with-single-bundle-hamstring-autograft-a-systematic-review
#9
REVIEW
Vincent Vg An, Corey Scholes, Vikram A Mhaskar, William Hadden, David Parker
BACKGROUND: Anterior cruciate ligament reconstruction (ACLR) is one of the most well studied and performed procedures in the world. Thus, it would be useful to develop a tool to predict patient outcomes post-operatively to allow clinicians to optimise management. PURPOSE: To identify and summarise factors predictive of graft failure and patient-reported outcome (PROM) measures at minimum two years after ACLR with single-bundle quadruple hamstring autograft via the anteromedial portal technique...
December 3, 2016: Knee
https://www.readbyqxmd.com/read/27915458/acl-deficiency-and-varus-osteoarthritis-high-tibial-osteotomy-alone-or-combined-with-acl-reconstruction
#10
Julian Mehl, Jochen Paul, Matthias J Feucht, Gerrit Bode, Andreas B Imhoff, Norbert P Südkamp, Stefan Hinterwimmer
INTRODUCTION: This study investigates the mid- to long-term clinical and radiological outcome in patients with symptomatic varus osteoarthritis (OA) and deficiency of the anterior cruciate ligament (ACL) and analyzes whether there are differences between isolated high tibial osteotomy (HTO) or combined single-stage HTO and ACL reconstruction (ACLR). METHODS: 26 patients who underwent HTO alone (group 1) and 26 patients who underwent single-stage HTO and ACLR (group 2) because of varus OA and ACL deficiency were examined at a mean of 5...
December 3, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27904222/functional-and-computed-tomography-correlation-of-femoral-and-tibial-tunnels-in-single-bundle-anterior-cruciate-ligament-reconstruction-use-of-accessory-anteromedial-portal
#11
Naveen Joseph Mathai, Rajkumar S Amaravathi, K V Pavan, Padmanabhan Sekaran, Gaurav Sharma, Belliappa Codanda
BACKGROUND: An accessory anteromedial portal (AAMP) has been shown to be effective in placing an anatomically ideal femoral tunnel. It is well known that this is due to the independent femoral drilling which is possible with the AAMP. However very little is known regarding the significance of this reconstruction technique in influencing the functional outcomes of anatomic anterior cruciate ligament reconstruction (ACLR). This study documents the influence of tibial and femoral tunnel positions on functional outcomes of anatomic ACLR using the AAMP...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27900267/depression-and-psychiatric-disease-associated-with-outcomes-after-anterior-cruciate-ligament-reconstruction
#12
REVIEW
Hao-Hua Wu, Max Liu, Joshua S Dines, John D Kelly, Grant H Garcia
While most patients with an anterior cruciate ligament (ACL) injury indicate satisfaction with surgical intervention, a significant proportion still do not return to pre-injury level of function or sport. Psychiatric comorbidities, such as depression, have recently been associated with poor clinical outcomes after ACL reconstruction (ACLR). To date, no article has yet examined how depression affects ACLR outcomes and how potential screening and intervention for psychological distress may affect postoperative activity level...
November 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/27881382/early-changes-in-knee-center-of-rotation-during-walking-after-anterior-cruciate-ligament-reconstruction-correlate-with-later-changes-in-patient-reported-outcomes
#13
Matthew R Titchenal, Constance R Chu, Jennifer C Erhart-Hledik, Thomas P Andriacchi
BACKGROUND: Altered knee kinematics after anterior cruciate ligament injury and reconstruction (ACLR) have been implicated in the development of posttraumatic osteoarthritis (PTOA), leading to poor long-term clinical outcomes. PURPOSE: This study was conducted to determine (1) whether the average knee center of rotation (KCOR), a multidimensional metric of knee kinematics, of the ACL-reconstructed knee during walking differs from that of the uninjured contralateral knee; (2) whether KCOR changes between 2 and 4 years after surgery; and (3) whether early KCOR changes predict patient-reported outcomes 8 years after ACLR...
November 23, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27861256/nonmodifiable-risk-factors-for-anterior-cruciate-ligament-injury
#14
Meghan J Price, Maria Tuca, Frank A Cordasco, Daniel W Green
PURPOSE OF REVIEW: As anterior cruciate ligament (ACL) injury is becoming increasingly prevalent in the population of active children and young adolescents, it is crucial to be aware of both the modifiable and nonmodifiable factors that place this population at increased ACL injury risk. Historically, there has not been a definitive consensus on all of these risk factors-particularly the nonmodifiable ones. RECENT FINDINGS: The present review has accumulated the most recent evidence for the nonmodifiable risk factors in ACL injury focusing particularly on female gender, generalized joint laxity, knee recurvatum, increased lateral tibial slope, decreased intercondylar notch width, structural lower extremity valgus, limb length discrepancy, family history, and history of contralateral knee ACL injury...
November 16, 2016: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/27859527/gait-mechanics-and-second-acl-rupture-implications-for-delaying-return-to-sport
#15
Jacob J Capin, Ashutosh Khandha, Ryan Zarzycki, Kurt Manal, Thomas S Buchanan, Lynn Snyder-Mackler
Second anterior cruciate ligament rupture is a common and devastating injury among young women who return to sport after ACL reconstruction, but it is inadequately understood. The purpose of this study was to compare gait biomechanics and return-to-sport time frames in a matched cohort of young female athletes who, after primary ACLR, returned to sport without re-injury or sustained a second ACL injury. Approximately 6 months after primary reconstruction, 14 young women (age 16 ± 2 years) involved in jumping, cutting, and pivoting sports underwent motion analysis testing after physical therapy and impairment resolution...
November 9, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27857501/prospective-study-of-the-anterior-cruciate-ligament-reconstruction-associated-with-high-tibial-opening-wedge-osteotomy-in-knee-arthritis-associated-with-instability
#16
Raju Vaishya, Vipul Vijay, Gyanendra Kumar Jha, Amit Kumar Agarwal
INTRODUCTION: Chronic ACL insufficiency with associated varus malalignment due to knee osteoarthritis (OA) is challenging to treat surgically. A combined ACL reconstruction (ACLR) with medial open wedge high tibial osteotomy (HTO) without using any metallic implant for HTO is an effective technique. MATERIALS AND METHOD: All the patients attending the outpatient department ACL injury and with associated medial compartment OA (Kellegren's grade 2 and grade 3) were considered for inclusion in the study...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27855310/between-leg-differences-in-challenging-single-limb-balance-performance-one-year-following-anterior-cruciate-ligament-reconstruction
#17
Anna L Hatton, Kay M Crossley, Ross A Clark, Timothy S Whitehead, Hayden G Morris, Adam G Culvenor
Following anterior cruciate ligament (ACL) rupture, reconstructive surgery (ALCR) is often performed to mechanically stabilise the knee, however functional deficits often persist long after surgery. Impaired single-limb standing balance has been observed in the ACLR limb compared to healthy individuals. However, it remains inconclusive as to whether these same balance deficits exist between the injured and contralateral uninjured limbs, during challenging balance tasks, and at a time when patients are permitted to return to sport...
November 11, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27820852/osteoarthritis-in-the-knee-joints-of-g%C3%A3-ttingen-minipigs-after-resection-of-the-anterior-cruciate-ligament-missing-correlation-of-mri-gene-and-protein-expression-with-histological-scoring
#18
Gregor Reisig, Michael Kreinest, Wiltrud Richter, Mechthild Wagner-Ecker, Dietmar Dinter, Ulrike Attenberger, Barbara Schneider-Wald, Stefan Fickert, Markus L Schwarz
INTRODUCTION: The Göttingen Minipig (GM) is used as large animal model in articular cartilage research. The aim of the study was to introduce osteoarthritis (OA) in the GM by resecting the anterior cruciate ligament (ACLR) according to Pond and Nuki, verified by histological and magnetic resonance imaging (MRI) scoring as well as analysis of gene and protein expression. MATERIALS AND METHODS: The eight included skeletally mature female GM were assessed after ACLR in the left and a sham operation in the right knee, which served as control...
2016: PloS One
https://www.readbyqxmd.com/read/27817301/neuroplasticity-associated-with-anterior-cruciate-ligament-reconstruction
#19
Dustin R Grooms, Stephen J Page, Deborah S Nichols-Larsen, Ajit M W Chaudhari, Susan E White, James A Onate
Study Design Controlled laboratory study. Background Anterior cruciate ligament (ACL) injury may result in neuroplastic changes due to lost mechanoreceptors of the ACL and compensations in neuromuscular control. These alterations are not completely understood. Assessing brain function after ACL injury and reconstruction with functional magnetic resonance imaging (fMRI), provides a means to address this gap in knowledge. Objective To investigate brain activation differences during knee flexion/extension in persons who have undergone ACL reconstruction (ACLR) and matched controls...
November 5, 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27802963/does-the-chronicity-of-anterior-cruciate-ligament-ruptures-influence-patient-reported-outcomes-before-surgery
#20
Joseph T Nguyen, David Wasserstein, Emily K Reinke, Kurt P Spindler, Nabil Mehta, John B Doyle, Robert G Marx
BACKGROUND: The time between an anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) may influence baseline knee-related and general health-related patient-reported outcome measures (PROMs). Despite the common use of PROMs as main outcomes in clinical studies, this variable has never been evaluated. PURPOSE: To compare baseline health-related quality of life measures and the prevalence/pattern of meniscal and articular cartilage lesions between patients who underwent acute and chronic ACLR so as to provide clinicians with benchmark PROMs in 2 different patient populations with ACL injuries...
November 1, 2016: American Journal of Sports Medicine
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