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Pyloric stenosis

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https://www.readbyqxmd.com/read/27855150/a-novel-missense-mutation-in-the-transcription-factor-foxf1-co-segregating-with-infantile-hypertrophic-pyloric-stenosis-in-the-extended-pedigree-linked-to-ihps5-on-chromosome-16q24
#1
Kate V Everett, Paris Ataliotis, Barry A Chioza, Charles Shaw-Smith, Eddie Mk Chung
BACKGROUND: The aim was to identify susceptibility alleles for infantile hypertrophic pyloric stenosis (IHPS) in a pedigree previously linked to IHPS5 on chromosome 16q24. METHODS: We screened the positional and functional candidate gene FOXF1 by Sanger sequencing in a single affected individual. All family members for whom DNA was available were genotyped to determine co-segregation status of the putative causal variant. Immunofluorescence studies were performed to compare the cellular localisation of wildtype and mutant form of the protein...
November 17, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27837525/a-case-report-of-curative-distal-gastrectomy-for-stage-iv-gastric-cancer-after-chemoradiotherapy-in-a-patient-with-a-gastrojejunal-gastric-bypass
#2
Masataka Shimonosono, Sumiya Ishigami, Takaaki Arigami, Yoshikazu Uenosono, Yasuto Uchikado, Yoshiaki Kita, Yuko Kijima, Hiroshi Kurahara, Yuko Mataki, Kosei Maemura, Shoji Natsugoe
BACKGROUND: Advanced gastric cancer in the lower third of the stomach often results in stricture of the gastric cavity and digestive symptoms. Gastrojejunostomy has been suggested to improve such symptoms, and the advent of new anticancer agents for gastric cancer has improved the response rate of the disease, which makes it possible to perform R0 gastrectomy in part of patients with stage IV gastric cancer. We experienced a rare case in which a patient with stage IV gastric cancer and cancerous pyloric stenosis was treated with R0 surgery after undergoing a gastrojejunal bypass procedure and multidisciplinary treatment...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27829521/a-randomized-trial-to-assess-advancement-of-enteral-feedings-following-surgery-for-hypertrophic-pyloric-stenosis
#3
Troy A Markel, Melissa R Scott, Samantha M Stokes, Alan P Ladd
PURPOSE: The rate of feeding advancement following surgery for hypertrophic pyloric stenosis (HPS) affects length of stay. We hypothesized that: 1) a relaxed feeding regimen following pyloromyotomy would allow infants to achieve feeding goals more quickly without affecting postoperative emesis, and 2) preoperative metabolic derangements would impair the ability to advance feedings following pyloromyotomy. METHODS: A prospective, randomized trial compared two postoperative feeding methods...
October 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27803770/update-on-endoscopic-management-of-gastric-outlet-obstruction-in-children
#4
REVIEW
Hsun-Chin Chao
Endoscopic balloon dilatation (EBD) and surgical intervention are two most common and effective treatments for gastric outlet obstruction. Correction of gastric outlet obstruction without the need for surgery is an issue that has been tried to be resolved in these decades; this management has developed with EBD, advanced treatments like local steroid injection, electrocauterization, and stent have been added recently. The most common causes of pediatric gastric outlet obstruction are idiopathic hypertrophic pyloric stenosis, peptic ulcer disease followed by the ingestion of caustic substances, stenosis secondary to surgical anastomosis; antral web, duplication cyst, ectopic pancreas, and other rare conditions...
October 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27775311/-infantile-hypertrofic-pyloric-stenosis-or-gastric-adenomyoma-differential-diagnosis-of-gastric-outlet-obstruction-in-children
#5
M Oviedo Gutiérrez, S Amat Valero, A Gómez Farpón, C Montalvo Ávalos, L Fernández García, D C Lara Cárdenas, S Barnes Marañón, C Granell Suárez, N Vega Mata, A J López López, M González Guerrero, V Álvarez Muñoz
PURPOSE: Gastrointestinal adenomyoma is a rare benign tumor most frequently located in the stomach. The differential diagnosis is wide because of its large clinical spectrum and unspecific radiological findings. Surgical excision is both diagnostic and therapeutic. CASE REPORT: A 49-days old girl presented with nonbilious vomiting of 48 hours of evolution. Infantile hypertrofic pyloric stenosis was suspected. Ultrasound showed a nonobstructive nodular lesion in the anterior pyloric wall...
July 20, 2015: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27757585/vomiting-in-an-infant-with-congenital-nephrotic-syndrome-questions
#6
Toshiyuki Takahashi, Yasuyuki Sato, Takeshi Yamazaki, Asako Hayashi, Takayuki Okamoto
BACKGROUND: Most patients with congenital nephrotic syndrome (CNS) exhibit a failure to thrive. A previous study reported that five of 41 (12 %) infants with CNS had hypertrophic pyloric stenosis (HPS) requiring surgery. The reason for this is undetermined, and there are few reports regarding the relationship between these conditions or their clinical course. CASE DIAGNOSIS/TREATMENT: We present the case of a 4-month-old girl with CNS. She did not show typical manifestations of HPS, but thickened mucosal and submucosal layers and hypertrophy of the pyloric muscle were detected by repeated ultrasound examinations prior to the diagnosis of HPS...
October 18, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27721721/incomplete-annular-pancreas-with-ectopic-opening-of-the-pancreatic-and-bile-ducts-into-the-pyloric-ring-first-report-of-a-rare-anomaly
#7
Shinjiro Kobayashi, Horoyuki Hoshino, Kouhei Segami, Satoshi Koizumi, Nobuyuki Ooike, Takehito Otsubo
The patient was a 56-year-old woman who had experienced epigastralgia and dorsal pain several times over the last 20 years. She was admitted for a diagnosis of acute cholecystitis, and severe intra- and extrahepatic bile duct dilatation with inner air density was noted. No papilla of Vater was present in the descending duodenum, and 2 small holes were present in the pyloric ring. Bile excretion from one of the small holes was observed under forward-viewing endoscope. It was considered that the pancreatic and bile ducts separately opened into the pyloric ring...
May 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27669400/hypertrophic-pyloric-stenosis-in-the-maritimes-examining-the-waves-of-change-over-time
#8
Alexander C Ednie, Ofer Amram, Jenna Colleen Creaser, Nadine Schuurman, Suzanne Leclerc, Natalie Yanchar
BACKGROUND: Changing patterns of referral and management of pediatric surgical conditions, including hypertrophic pyloric stenosis (HPS), have recently been described and often relate to comfort with early nonoperative management, anesthesia and corrective surgery. Travelling distance required for treatment at pediatric centres can also be burdensome for families. We assessed referral patterns for HPS in the maritime provinces of Canada over 10 years to quantify the burden on families travelling for surgical care...
October 1, 2016: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/27642452/infantile-hypertrophic-pyloric-stenosis-with-unusual-presentations-in-sagamu-nigeria-a-case-report-and-review-of-the-literature
#9
Tinuade Adetutu Ogunlesi, Opeyemi Temitola Kuponiyi, Collins Chigbundu Nwokoro, Ibukunolu Olufemi Ogundele, Gbenga Fakunle Abe, Olusoga Babatunde Ogunfowora
A 24-day old female Nigerian neonate presented with protracted vomiting, fever and dehydration but without palpable abdominal tumour or visible gastric peristalsis. There was no derangement of serum electrolytes. The initial working diagnosis was Late-Onset Sepsis but abdominal ultrasonography showed features consistent with the diagnosis of IHPS. This case report highlights the atypical presentation of this surgical condition and the need to investigate cases of protracted vomiting in the newborn with at least, ultrasonography to minimize complications and reduce the risk of mortality in a resource-poor setting...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27599310/adult-onset-idiopathic-hypertrophic-pyloric-stenosis-associated-with-osteoglophonic-dysplasia-and-hiv-case-report-and-review-of-literature
#10
Justin Holder, Daniel Zinn, Amiram Samin
Adult-onset hypertrophic pyloric stenosis (HPS) is a rare anomaly that can be idiopathic or related to underlying gastric pathology. We describe a case of a 25-year-old man with history of human immunodeficiency virus and osteoglophonic dysplasia who presented with pain and swelling at a gastrostomy site. Computed tomography and upper gastrointestinal barium swallow demonstrated gastric distention and stricture at the distal portion of the gastric antrum. An ultrasound detected HPS. The patient eventually required pyloromyotomy for treatment...
September 2, 2016: Ultrasound Quarterly
https://www.readbyqxmd.com/read/27586849/health-disparities-in-infants-with-hypertrophic-pyloric-stenosis
#11
Alexander Feliz, Janette L Holub, Nima Azarakhsh, Marielena Bachier-Rodriguez, Kate B Savoie
BACKGROUND: This study investigates whether health disparities exist in infants with hypertrophic pyloric stenosis (HPS), to identify factors affecting definitive treatment, and if more morbidity occurs. METHODS: A 6-year retrospective analysis was performed on infants with HPS. Analysis of variance was used to evaluate the impact of socioeconomic factors on disease severity and hospitalization. General linear models were used to assess the impact of risk factors on the outcomes...
August 4, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27551336/abdominal-ultrasonography-of-the-pediatric-gastrointestinal-tract
#12
REVIEW
Heather I Gale, Michael S Gee, Sjirk J Westra, Katherine Nimkin
Ultrasound is an invaluable imaging modality in the evaluation of pediatric gastrointestinal pathology; it can provide real-time evaluation of the bowel without the need for sedation or intravenous contrast. Recent improvements in ultrasound technique can be utilized to improve detection of bowel pathology in children: Higher resolution probes, color Doppler, harmonic and panoramic imaging are excellent tools in this setting. Graded compression and cine clips provide dynamic information and oral and intravenous contrast agents aid in detection of bowel wall pathology...
July 28, 2016: World Journal of Radiology
https://www.readbyqxmd.com/read/27549430/acute-kidney-injury-following-ingestion-of-plate-developer-sodium-metasilicate-a-case-report
#13
B G A Rathnamali, G Samarajiwa, D D K Abeyratne, G N D Perera, S B Gunatilake
BACKGROUND: Plate developer is a chemical used in the printing industry and is a corrosive alkaline agent containing sodium metasilicate as the main substance. Plate developer poisoning is rare. Literature search revealed only a single case report of fatal sodium metasilicate poisoning (Z Rechtsmed 94(3):245-250, 1985). There are no reports of acute kidney injury related to ingestion of sodium metasilicate containing substances. CASE REPORT: A 52-year-old Sri Lankan male with a history of hypertension and affective disorder presented following ingestion of about 150 ml of plate developer solution...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/27532616/top-to-bottom-a-new-method-for-assessing-adequacy-of-laparoscopic-pyloromyotomy
#14
Maria E Linnaus, Crystal S Langlais, Kevin N Johnson, David M Notrica
INTRODUCTION: Hypertrophic pyloric stenosis is a commonly encountered pediatric surgical issue. Initially treated with open surgical techniques, many pediatric surgeons have adopted the minimally invasive approach using laparoscopy. However, some concerns exist that the rate of incomplete pyloromyotomy is elevated in laparoscopy. We propose a new technique to assess the adequacy of laparoscopic pyloromyotomy. METHODS: Adequacy of laparoscopic pyloromyotomy was assessed by confirming that the top of the serosa on one side of the pylorus has adequate freedom to reach the bottom of the muscle on other side...
August 17, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27528563/operative-outcomes-of-infantile-hypertrophic-pyloric-stenosis-in-patients-with-congenital-heart-disease
#15
Shin Miyata, Jayun Cho, Kazuhide Matsushima, Aaron Fowler, David W Bliss
PURPOSE: This study aims to compare the outcomes of pyloromyotomy for infantile hypertrophic pyloric stenosis (IHPS) in children with and without congenital heart disease (CHD). METHODS: A retrospective, single pediatric center, case-control, matched cohort study was performed over 10years. A case of IHPS with CHD was paired with control patients of IHPS without CHD, matched by age and gender. Perioperative morbidity, 30-day mortality, length of hospital stay, and hospital cost were compared...
November 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27521712/contemporary-management-of-pyloric-stenosis
#16
Matthew Jobson, Nigel J Hall
Hypertrophic pyloric stenosis is a common surgical cause of vomiting in infants. Following appropriate fluid resuscitation, the mainstay of treatment is pyloromyotomy. This article reviews the aetiology and pathophysiology of hypertrophic pyloric stenosis, its clinical presentation, the role of imaging, the preoperative and postoperative management, current surgical approaches and non-surgical treatment options. Contemporary postoperative feeding regimens, outcomes and complications are also discussed.
August 2016: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/27506212/late-onset-hypertrophic-pyloric-stenosis-with-gastric-outlet-obstruction-case-report-and-review-of-the-literature
#17
Lindsey L Wolf, Amar Nijagal, Alejandro Flores, Terry L Buchmiller
We report late-onset hypertrophic pyloric stenosis in a 17-year-old female. She presented with abdominal pain and an episode of upper gastrointestinal hemorrhage and subsequently developed gastric outlet obstruction. Work-up revealed circumferential pyloric thickening, delayed gastric emptying, and a stenotic, elongated pyloric channel. Biopsies showed benign gastropathy, negative for Helicobacter pylori, without eosinophilic infiltrates. Botulinum toxin injection provided limited relief. Diagnostic laparoscopy confirmed the hypertrophic pylorus and we performed laparoscopic pyloromyotomy...
October 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27498936/a-case-of-large-cell-neuroendocrine-carcinoma-of-the-stomach-with-multiple-liver-metastases
#18
Yoko Kominami, Satoko Kunita, Katsunori Tsuga, Miwako Tanaka, Mitsuhiro Kamigaki, Shinya Aoki, Hiroyuki Ito, Shinji Tanaka, Kazuaki Chayama
A 79-year-old man was admitted to our hospital to determine the cause of his melena. He underwent esophagogastric endoscopy and computed tomography, revealing a submucosal tumor on the anterior wall of the gastric antrum with multiple liver metastases. Endoscopic biopsy revealed a large cell neuroendocrine cell carcinoma. A subtotal gastrostomy was performed to prevent pyloric stenosis and anemia caused by tumor hemorrhage. Previous studies on gastric neuroendocrine carcinoma reported poor prognosis. Large- and small-cell types of gastric neuroendocrine carcinomas were differentiated for the first time in the 14th edition of the Japanese Classification of Gastric Carcinoma...
August 2016: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/27486645/azithromycin-pyloric-stenosis-in-neonates
#19
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Prescrire International
https://www.readbyqxmd.com/read/27439633/treating-idiopathic-hypertrophic-pyloric-stenosis-with-sequential-therapy-a-clinical-study
#20
Jianfeng Fan, Yingzuo Shi, Ming Cheng, Xiaomin Zhu, Dafeng Wang
AIM: The aim of this study was to explore the efficacy and safety of treating idiopathic hypertrophic pyloric stenosis with sequential therapy (ST). METHODS: From January 2010 to June 2013, 49 children with idiopathic hypertrophic pyloric stenosis were divided into two groups to accept either atropine ST (ST group, n = 26) or laparoscopic surgery (operation group, n = 23). The remission rate of vomiting, complications, hospital stay and medical expenditure were compared between the two groups...
July 2016: Journal of Paediatrics and Child Health
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