keyword
MENU ▼
Read by QxMD icon Read
search

msp_1

keyword
https://www.readbyqxmd.com/read/28442543/effect-of-informal-employment-on-the-relationship-between-psychosocial-work-risk-factors-and-musculoskeletal-pain-in-central-american-workers
#1
David Gimeno Ruiz de Porras, Marianela Rojas Garbanzo, Aurora Aragón, Lino Carmenate-Milián, Fernando G Benavides
INTRODUCTION: The constant increase on the psychosocial demands experienced at work seems to contribute to the increase in health problems such as musculoskeletal pain (MSP). This association may be especially important in low-income and middle-income countries, where there is a large proportion of informal workers among whom there is little research. We analysed the association between psychosocial work risk factors and MSP among formal and informal workers using the First Central American Survey of Working Conditions and Health...
April 25, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28401903/impact-of-metric-and-sample-size-on-determining-malaria-hotspot-boundaries
#2
Gillian H Stresman, Emanuele Giorgi, Amrish Baidjoe, Phil Knight, Wycliffe Odongo, Chrispin Owaga, Shehu Shagari, Euniah Makori, Jennifer Stevenson, Chris Drakeley, Jonathan Cox, Teun Bousema, Peter J Diggle
The spatial heterogeneity of malaria suggests that interventions may be targeted for maximum impact. It is unclear to what extent different metrics lead to consistent delineation of hotspot boundaries. Using data from a large community-based malaria survey in the western Kenyan highlands, we assessed the agreement between a model-based geostatistical (MBG) approach to detect hotspots using Plasmodium falciparum parasite prevalence and serological evidence for exposure. Malaria transmission was widespread and highly heterogeneous with one third of the total population living in hotspots regardless of metric tested...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28388873/changes-in-the-dna-methylation-and-hydroxymethylation-status-of-the-intercellular-adhesion-molecule-1-gene-promoter-in-thyrocytes-from-autoimmune-thyroiditis-patients
#3
Tingting Liu, Jie Sun, Zhaojun Wang, Wenqing Yang, Hao Zhang, Chenling Fan, Zhongyan Shan, Weiping Teng
BACKGROUND: The intercellular adhesion molecule 1 (ICAM1) gene is not expressed in normal thyroid tissue but was shown to be expressed in the thyroid tissue of autoimmune thyroiditis (AIT) patients. METHODS: This study aimed to explore whether the DNA methylation and hydroxymethylation status of the ICAM1 promoter are aberrantly altered in the thyroid cells of AIT patients and whether this change is associated with dysfunctional expression of ICAM1. A total of 35 AIT patients and 35 sex- and age-matched controls were studied...
April 7, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28350483/a-qualitative-study-of-a-maintenance-support-program-for-women-at-risk-of-homelessness-part-1-personal-factors
#4
Rose McMaster, Violeta Lopez, Rachel Kornhaber, Michelle Cleary
In this article, a qualitative study of homeless women and their experiences attending a Maintenance Support Programme (MSP) is discussed. The overarching theme that emerged from the study of women in the MSP was 'A life-changing event: I have the power to change'. The article focuses on the first of the sub-themes: personal factors including: (a) health status, (b) beliefs and attitudes, (c) knowledge, and (d) life and interpersonal skills. Findings demonstrate the influence that these factors have on the capacity of homeless women to change their lives...
March 28, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28341111/generation-characterization-and-immunogenicity-of-a-novel-chimeric-recombinant-protein-based-on-plasmodium-vivax-ama-1-and-msp119
#5
Mariana Vilela Rocha, Kátia Sanches Françoso, Luciana Chagas Lima, Tarsila Mendes Camargo, Ricardo L D Machado, Fabio T M Costa, Laurent Rénia, Francois Nosten, Bruce Russell, Mauricio M Rodrigues, Irene S Soares
Plasmodium vivax is the most widely distributed malaria species and the most prevalent species of malaria in America and Asia. Vaccine development against P. vivax is considered a priority in the global program for the eradication of malaria. Earlier studies have characterized the Apical Membrane Antigen 1 (AMA-1) ectodomain and the C-terminal region (19kDa) of the Merozoite Surface Protein 1 (MSP-1) of P. vivax as immunodominant antigens. Based on this characterization, we designed a chimeric recombinant protein containing both merozoite immunodominant domains (PvAMA166-MSP119)...
March 21, 2017: Vaccine
https://www.readbyqxmd.com/read/28341016/the-role-of-alcohol-expectancies-in-sexual-risk-behaviors-among-adolescents-and-young-adults-in-the-democratic-republic%C3%A2-of-the%C3%A2-congo
#6
Emily A Hurley, Heena Brahmbhatt, Patrick K Kayembe, Michelle-Alphonsine Fatuma Busangu, Ma-Umba Mabiala, Deanna Kerrigan
PURPOSE: Considering the increased risk of HIV among alcohol users, we explored the role of individual alcohol expectancies in risk behaviors among youth in the Democratic Republic of the Congo. METHODS: We surveyed 1,396 adolescents (ages 15-19) and young adults (ages 20-24) on alcohol and sexual behaviors in May, 2010. We assessed expectancies of alcohol use (1) leading to sex or positive sexual experiences; (2) diminishing one's ability to resist unwanted sex; and (3) diminishing one's ability to use or negotiate use of condoms...
January 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28328577/parkinson-disease-and-musculoskeletal-pain-an-8-year-population-based-cohort-study
#7
Wei-Hung Lien, Wei-Chih Lien, Ta-Shen Kuan, Shang-Te Wu, Yi-Ting Chen, Ching-Ju Chiu
The aim of this study was to evaluate the incidence and clinical features of musculoskeletal pain (MSP) in patients with Parkinson disease (PD) compared with a control group without the disease. The retrospective cohort study used a subset of the Taiwan National Health Insurance Research Database (NHIRD) comprising information on 1 million beneficiaries randomly sampled from the entire population of Taiwan. A total of 490 patients aged 50 and above with newly diagnosed Parkinson disease were identified during a period from 2000 to 2005...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28327424/cellulase-assisted-extraction-of-polysaccharides-from-malva-sylvestris-process-optimization-and-potential-functionalities
#8
Hosein Rostami, Seyed Mohammad Taghi Gharibzahedi
Enzyme-assisted extraction process of the water-soluble Malva sylvestris polysaccharides (MSPs) was optimized using response surface methodology (RSM). The highest yield (10.40%) of MSPs was achieved at 5.64% cellulase, 55.65°C temperature, 3.4h time, and 5.22 pH. Three homogeneous polysaccharide fractions (MSP-1, MSP-2, MSP-3) were purified by DEAE-cellulose and Sephadex G-100 chromatography, which were composed of galactose, glucuronic acid, arabinose, rhamnose and mannose in different molar ratios with molecular weight range of 2...
March 19, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28322550/multiplex-substrate-profiling-by-mass-spectrometry-for-kinases-as-a-method-for-revealing-quantitative-substrate-motifs
#9
Nicole O Meyer, Anthony J O'Donoghue, Ursula Schulze-Gahmen, Matthew Ravalin, Steven M Moss, Michael B Winter, Giselle M Knudsen, Charles S Craik
The more than 500 protein kinases comprising the human kinome catalyze hundreds of thousands of phosphorylation events to regulate a diversity of cellular functions; however, the extended substrate specificity is still unknown for many of these kinases. We report here a method for quantitatively describing kinase substrate specificity using an unbiased peptide library-based approach with direct measurement of phosphorylation by tandem liquid chromatography-tandem mass spectrometry (LC-MS/MS) peptide sequencing (multiplex substrate profiling by mass spectrometry, MSP-MS)...
April 4, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28319413/aberrant-promoter-hypermethylation-of-p16-survivin-and-retinoblastoma-in-gastric-cancer
#10
L Guo, C Huang, Q J Ji
BACKGROUND: Gastric cancer is common and can be found throughout the world. Notoriously like other cancers, gastric cancer is a consequence of cellular regulation disorder. Epigenetics, including many oncogenes or tumour suppressor genes, can provide some clues for this kind of disorder. DNA methylation, especially promoter methylation, which causes the silence/decrease of tumour related genes, has become a focus in various tumour types. The aim of this study was to investigate promoter methylation of certain genes: p16, survivin, retinoblastoma (Rb), all of which have been regarded as genes related to gastric cancer...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28317222/standardized-total-tract-digestibility-of-phosphorus-in-various-inorganic-phosphates-fed-to-growing-pigs
#11
Woong Bi Kwon, Beob Gyun Kim
An experiment was conducted to determine the standardized total tract digestibility (STTD) of phosphorus (P) in five sources of inorganic phosphate fed to growing pigs, including dicalcium phosphate (DCP), monodicalcium phosphate (MDCP), monocalcium phosphate (MCP), tricalcium phosphate (TCP) and monosodium phosphate (MSP, reagent grade). Six barrows (42.4 ± 1.1 kg) individually housed in metabolism crates were allotted to a 6 × 6 Latin square design with six dietary treatments and six periods. Each experimental period consisted of a 4 day adaptation period and a 5 day collection period...
March 20, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28299336/shisa3-promoter-methylation-is-a-potential-diagnostic-and-prognostic-biomarker-for-laryngeal-squamous-cell-carcinoma
#12
Zhisen Shen, Chongchang Zhou, Jinyun Li, Dong Ye, Hongxia Deng, Bin Cao, Wenjuan Hao, Lexi Lin, Yuna Zhang
The purpose of this study was to evaluate the contribution of SHISA3 promoter methylation to laryngeal squamous cell carcinoma (LSCC). SHISA3 promoter methylation status and expression were determined using methylation-specific polymerase chain reaction (MSP) and quantitative real-time PCR (qRT-PCR) in 93 paired LSCC and adjacent normal tissues, respectively. Furthermore, the regulatory function of the SHISA3 promoter fragment was analyzed using a luciferase reporter assay. The results reveal that there is a significant increase in SHISA3 methylation in LSCC tissues compared with corresponding nontumor tissues (P = 4...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28292856/light-regulated-expression-of-sensor-histidine-kinase-cki1-controls-cytokinin-related-development
#13
Tereza Dobisova, Vendula Hrdinova, Candela Cuesta, Sarka Michlickova, Ivana Urbankova, Romana Hejatkova, Petra Žádníková, Marketa Pernisova, Eva Benkova, Jan Hejatko
In plants, the multistep phosphorelay (MSP) pathway mediates a range of regulatory processes, including those activated by cytokinins. The crosstalk between cytokinin response and light is known for a long time. However, the molecular mechanism underlying the interactionbetween light and cytokinin signaling remains elusive. In the screen for upstream regulators we identified a LONG PALE HYPOCOTYL (LPH) gene whose activity is indispensable for spatiotemporally correct expression of CYTOKININ INDEPENDENT-1 (CKI1), encoding the constitutively active sensor histidine kinase that activates MSP signaling...
March 14, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28288602/is-being-a-regular-player-with-fewer-teammates-associated-with-musculoskeletal-pain-in-youth-team-sports-a-cross-sectional-study
#14
Takafumi Abe, Masamitsu Kamada, Jun Kitayuguchi, Shinpei Okada, Yoshiteru Mutoh, Yuji Uchio
BACKGROUND: Musculoskeletal pain (MSP) is a commonly reported symptom in youth sports players. Some sports-related risk factors have been reported, but previous studies on extrinsic risk factors did not focus on management of team members (e.g., regular or non-regular players, number of players) for reducing sports-related MSP. This study aimed to examine the association of playing status (regular or non-regular players) and team status (fewer or more teammates) with MSP in youth team sports...
March 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28287924/individual-and-work-related-risk-factors-for-musculoskeletal-pain-among-computer-workers-in-nigeria
#15
Ukachukwu Okoroafor Abaraogu, Paschal Nzubechukwu Okorie, Deborah Onyinyechukwu Duru, Elochukwu Fortune Ezenwankwo
We investigated the prevalence of musculoskeletal pain (MSP) and the association of 1-month prevalence with individual and work-related factors among commercial typists in Enugu. Participants responded to a questionnaire about occurrences of MSP and a 75.6% (242/320) response rate was achieved. Prevalence was summarized in frequencies and percentages while associations between MSPs and risk factors were explored using chi-square. MSP was most common in the low back (58.3%), and low back pain limited 51.7% from activities between 1 and 30 days...
March 13, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28268222/rassf10-is-epigenetically-inactivated-and-suppresses-cell-proliferation-and-induces-cell-apoptosis-by-activating-the-p53-signalling-pathway-in-papillary-thyroid-carcinoma-cancer
#16
Cheng Fan, Wendy Wang, Ji Jin, Zhuo Yu, Xiping Xin
OBJECTIVES: We aimed to confirm whether RASSF10 activated the p53 signalling pathway, thereby modulating cell proliferation, migration, invasion, and apoptosis in papillary thyroid carcinoma (PTC) cells. METHODS: A total of 108 PTC tissue samples and normal adjacent tissues were obtained. RT-PCR and Western blotting analyses were performed to detect RASSF10 expression, and methylation levels of RASSF10 were estimated by methylation-specific PCR (MSP). We also detected the expression and methylation status of RASSF10 in both a human PTC cell line (K1) and a normal thyroid cell line (FRTL5)...
March 7, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28253867/the-shape-of-the-iceberg-quantification-of-submicroscopic-plasmodium-falciparum-and-plasmodium-vivax-parasitaemia-and-gametocytaemia-in-five-low-endemic-settings-in-ethiopia
#17
Fitsum G Tadesse, Lotus van den Hoogen, Kjerstin Lanke, Jodie Schildkraut, Kevin Tetteh, Abraham Aseffa, Hassen Mamo, Robert Sauerwein, Ingrid Felger, Chris Drakeley, Endalamaw Gadissa, Teun Bousema
BACKGROUND: The widespread presence of low-density asymptomatic infections with concurrent gametocytes may be a stumbling block for malaria elimination. This study investigated the asymptomatic reservoir of Plasmodium falciparum and Plasmodium vivax infections in schoolchildren from five settings in northwest Ethiopia. METHODS: Two cross-sectional surveys were conducted in June and November 2015, enrolling 551 students from five schools and 294 students from three schools, respectively...
March 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28243814/dna-diagnosis-of-peritoneal-fluid-cytology-test-by-cdo1-promoter-dna-hypermethylation-in-gastric-cancer
#18
Hideki Ushiku, Keishi Yamashita, Akira Ema, Naoko Minatani, Mariko Kikuchi, Ken Kojo, Keigo Yokoi, Toshimichi Tanaka, Nobuyuki Nishizawa, Satoru Ishii, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Natsuya Katada, Shiro Kikuchi, Hiroshi Katoh, Masahiko Watanabe
BACKGROUND: Minimal residual disease of the peritoneum is challenging for early cancer detection in gastric cancer (GC). Utility of PCR amplification of cancer-derived DNA has been considered feasible due to its molecular stability, however such markers have never been available in GC clinics. We recently discovered cancer-specific methylation of CDO1 gene in GC, and investigated the clinical potential to detect the minimal residual disease. METHODS: One hundred and two GC patients were investigated for peritoneal fluid cytology test (CY), and detection level of the promoter DNA methylation of CDO1 gene was assessed by quantitative methylation specific PCR (Q-MSP) in the sediments (DNA CY)...
February 27, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28219126/-clinical-significance-of-hypermethylation-of-dlc-1-gene-in-myelodysplastic-syndrome-patients-and-effects-of-decitabine-on-dlc-1-gene-expression
#19
H Y Fu, H R Zhou, J G Yan, C J Chen, J Z Shen
Objective: To detect the methylation status of DLC-1 gene in the patients with myelodysplastic syndrome(MDS), the effect of abnormal methylation of DLC-1 gene on the expression of DLC-1 gene, the clinical significance of methylation of DLC-1 gene in MDS patients, and the effect of decitabine on DLC-1 gene expression. Methods: A total of 43 MDS patients were treated in Fujian Medical University Union Hospital from 2013 to 2015. Methylation status of DLC-1 gene in MDS patients were detected by the methylation specific PCR(MSP)...
February 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28215872/detection-of-specific-antibodies-in-cats-infected-with-the-lung-nematode-aelurostrongylus-abstrusus
#20
Eva-Maria Zottler, Christina Strube, Manuela Schnyder
Feline aelurostrongylosis, caused by the metastrongylid nematode Aelurostrongylus abstrusus, is an underestimated respiratory parasitosis. Its diagnosis currently mainly relies on the isolation of first stage larvae from fresh faecal samples. The aim of our study was to develop a serological test for the detection of specific antibodies against A. abstrusus by ELISA. We used recombinant major sperm protein (MSP) of the bovine lungworm Dictyocaulus viviparus as detection antigen and evaluated two different ELISA plates (Maxisorp and Immobilizer™ Amino-plate, Nunc Roskilde, Denmark) with two different enzyme systems [alkaline phosphatase (AP) and horseradish peroxidase (HRP)]...
February 15, 2017: Veterinary Parasitology
keyword
keyword
93946
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"