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https://www.readbyqxmd.com/read/28323770/to-the-editor
#1
Kadri Altundag
No abstract text is available yet for this article.
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323427/kinetin-riboside-and-its-protides-activate-the-parkinson-s-disease-associated-pten-induced-putative-kinase-1-pink1-independent-of-mitochondrial-depolarisation
#2
Laura Osgerby, Yu-Chiang Lai, Peter J Thornton, Joseph Amalfitano, Cécile S Le Duff, Iqra Jabeen, Hachemi Kadri, Ageo Miccoli, James H R Tucker, Miratul M K Muqit, Youcef Mehellou
Since loss of function mutations of PINK1 lead to early-onset Parkinson's disease, there has been growing interest in the discovery of small molecules that amplify the kinase activity of PINK1. We herein report the design, synthesis, serum stability and hydrolysis of four kinetin riboside ProTides. These ProTides, along with kinetin riboside, activated PINK1 in cells independent of mitochondrial depolarization. This highlights the potential of modified nucleosides and their phosphate prodrugs as treatments for neurodegenerative diseases...
March 21, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28316310/three-port-two-located-on-the-pfannenstiel-line-laparoscopic-cholecystectomy-comparison-with-traditional-laparoscopic-cholecystectomy
#3
Musa Akoglu, Erdal Birol Bostanci, Muhammet Kadri Colakoglu, Erol Aksoy
Laparoscopic cholecystectomy (LC) is seen as a gateway to minimally invasive surgery. We defined a new three-port technique with different port sites and compared the postoperative results with traditional four-port LC procedure in a case-match study. Between June 2012 and May 2013, 104 consecutive patients underwent three-port LC by same experienced surgeon. In the same center, 2963 consecutive patients underwent four-port LC, and of these 2963 patients, a matched group of 104 patients was selected. Data included patient age, gender, body mass index, American Society of Anesthesiologists score, history of abdominal operations, intraoperative data about operating time and conversion to open surgery, and postoperative data about length of hospital stay and postoperative complications were recorded prospectively...
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28315570/tp-e-interval-and-tp-e-qtc-ratio-as-novel-surrogate-markers-for-prediction-of-ventricular-arrhythmic-events-in-hypertrophic-cardiomyopathy
#4
Mehmet Kadri Akboğa, Kevser Gülcihan Balcı, Samet Yılmaz, Selahattin Aydın, Çağrı Yayla, Ahmet Göktuğ Ertem, Sefa Ünal, Mustafa Mücahit Balcı, Yücel Balbay, Dursun Aras, Serkan Topaloğlu
OBJECTIVE: Hypertrophic cardiomyopathy (HCM) as a common genetic heart disease characterized by ventricular hypertrophy and myocardial fibrosis is significantly associated with a higher risk of fatal ventricular arrhythmic events (VAEs). We aimed to assess the interval between the peak and the end of the electrocardiographic T wave (Tp-e) and Tp-e/corrected QT (QTc) ratio as candidate markers of ventricular arrhythmias in patients with HCM. METHODS: In this single-center, prospective study, a total of 66 patients with HCM and 88 controls were enrolled...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28303155/adulteration-and-contamination-of-commercial-sap-of-hymenaea-species
#5
Katyuce de Souza Farias, Sarah Alves Auharek, Andréa Luiza Cunha-Laura, Jeana Mara Escher de Souza, Geraldo Alves Damasceno-Junior, Mônica Cristina Toffoli-Kadri, Wander Fernando de Oliveira Filiú, Edson Dos Anjos Dos Santos, Marilene Rodrigues Chang, Carlos Alexandre Carollo
The Hymenaea stigonocarpa and Hymenaea martiana species, commonly known as "jatobá," produce a sap which is extracted by perforation of the trunk and is commonly used in folk medicine as a tonic. For this study, the authenticity of commercial samples of jatobá was verified by the identification of the main compounds and multivariate analysis and contamination by microbial presence analysis. The acute toxicity of the authentic jatobá sap was also evaluated. The metabolites composition and multivariate analysis revealed that none of the commercial samples were authentic...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28295609/serum-galectin-3-level-as-a-marker-of-thrombogenicity-in-atrial-fibrillation
#6
Duygu Kocyigit, Kadri Murat Gurses, Muhammed Ulvi Yalcin, Hande Canpinar, Ugur Canpolat, Banu Evranos, Hikmet Yorgun, Necla Ozer, Dicle Guc, Kudret Aytemir
BACKGROUND: Left atrial appendage flow velocity (LAAFV) and presence of spontaneous echo contrast (SEC) have been reported to be predictors of thromboembolism in atrial fibrillation (AF) patients. Galectin-3 is a biomarker reflecting pro-inflammatory status, whose role in AF has recently drawn attention, particularly in persistent AF population. AIM: In this study we aimed to investigate the association between serum galectin-3 levels and echocardiographic predictors of thromboembolism in persistent AF patients...
March 13, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28295178/granulocyte-transfusions-in-the-management-of-invasive-fungal-infections
#7
REVIEW
Kamille A West, Juan Gea-Banacloche, David Stroncek, Sameer S Kadri
Granulocyte transfusions have a long history of being used in patients with neutropenia or neutrophil dysfunction to prevent and treat invasive fungal infections. However, there are limited and conflicting data concerning its clinical effectiveness, considerable variations in current granulocyte transfusion practices, and uncertainties about its benefit as an adjunct to modern antifungal therapy. In this review, we provide an overview on granulocyte transfusions and summarize the evidence on their role in the prevention and treatment of invasive fungal infections...
March 14, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28293229/fungal-root-microbiome-from-healthy-and-brittle-leaf-diseased-date-palm-trees-phoenix-dactylifera-l-reveals-a-hidden-untapped-arsenal-of-antibacterial-and-broad-spectrum-antifungal-secondary-metabolites
#8
Fedia B Mefteh, Amal Daoud, Ali Chenari Bouket, Faizah N Alenezi, Lenka Luptakova, Mostafa E Rateb, Adel Kadri, Neji Gharsallah, Lassaad Belbahri
In this study, we aimed to explore and compare the composition, metabolic diversity and antimicrobial potential of endophytic fungi colonizing internal tissues of healthy and brittle leaf diseased (BLD) date palm trees (Phoenix dactylifera L.) widely cultivated in arid zones of Tunisia. A total of 52 endophytic fungi were isolated from healthy and BLD roots of date palm trees, identified based on internal transcribed spacer-rDNA sequence analysis and shown to represent 13 species belonging to five genera. About 36...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28291775/comment-on-nomogram-to-predict-pathologic-complete-response-in-her2-positive-breast-cancer-treated-with-neoadjuvant-systemic-therapy
#9
Kadri Altundag
No abstract text is available yet for this article.
March 14, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28281934/integron-occurrence-is-linked-to-reduced-biocide-susceptibility-in-multidrug-resistant-pseudomonas-aeruginosa
#10
Ashraf A Kadry, Fathy M Serry, Amira M El-Ganiny, Ahmed M El-Baz
OBJECTIVE: Integrons are gene acquisition systems commonly found in bacterial genomes that play a major role in the dissemination of resistance to antibiotics. This work aimed to study the relationship between the presence of integrons and the reduced susceptibility of multidrug-resistant (MDR) Pseudomonas aeruginosa isolates towards different groups of biocides. METHODS: The antimicrobial susceptibility patterns of 104 clinical isolates were determined against different antibiotics by the disk diffusion method...
March 10, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28272125/perioperative-tamoxifen-use-and-risk-of-deep-vein-thrombosis-role-of-caprini-risk-assessment-model-should-not-be-discarded
#11
Kadri Altundag
No abstract text is available yet for this article.
April 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28271308/genetic-structure-of-a-regionally-endangered-orchid-the-dark-red-helleborine-epipactis-atrorubens-at-the-edge-of-its-distribution
#12
Hilde Hens, Anne Jäkäläniemi, Kadri Tali, Petr Efimov, Alexey V Kravchenko, Laura Kvist
The genetic structure and diversity of species is determined by both current population dynamics and historical processes. Population genetic structure at the edge of the distribution is often expected to differ substantially from populations at the centre, as these edge populations are often small and fragmented. In addition, populations located in regions that have experienced repeated glaciations throughout the Pleistocene, may still carry imprints from the genetic consequences of frequent distribution shifts...
March 7, 2017: Genetica
https://www.readbyqxmd.com/read/28268123/brain-proteomic-modifications-associated-to-protective-effect-of-grape-extract-in-a-murine-model-of-obesity
#13
Smine Selima, Obry Antoine, Kadri Safwen, Hardouin Julie, Fréret Manuel, Amri Mohamed, Jouenne Thierry, Limam Ferid, Cosette Pascal, Aouani Ezzedine
No abstract text is available yet for this article.
March 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28266794/synthesis-and-characterization-of-chiral-triazole-based-halogen-bond-donors-halogen-bonds-in-solid-state-and-in-solution
#14
Mikk Kaasik, Sandra Kaabel, Kadri Kriis, Ivar Järving, Riina Aav, Kari Rissanen, Tõnis Kanger
A general platform for the synthesis of various chiral halogen bond (XB) donors and characterization of factors that influence the strength of the halogen bond in the solid state and in solution is presented. The XB donors are based on the triazole core. The characterization of XB donors in the solid state by X-ray crystallography and in solution by 1H NMR titration can be used to aid the design of new XB donors. We describe the first example of a XB between iodotriazoles and thioureas in solution. In addition, the enantiodiscrimination of acceptors in solution via halogen bond participation is described...
March 7, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28266775/bone-marrow-derived-mesenchymal-stem-cells-mitigate-caspase-3-and-8-hydroxy-proline-induced-via-%C3%AE-adrenergic-agonist-in-pulmonary-injured-rats
#15
Mai O Kadry, Rehab M Abdel-Megeed
Estimating the ability of bone marrow-derived mesenchymal stem cells (BM-MSCs) to alleviate pulmonary injury induced via isoproterenol (ISP). ISP was injected in a dose of (100 mg/kg, subcutaneously twice at an interval of 24 h). One month post BM-MSCs transplantation by intravenous injection, pulmonary oxidative stress was assessed, and Western blot analyses and histopathological investigations were conducted. Compared with the normal control group, BM-MSCs transplantation significantly decreased the expression of pulmonary anti-oxidative stress marker...
March 7, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28266762/downregulation-of-hif1-%C3%AE-smad-2-akt-and-bax-gene-expression-in-sodium-nitrite-induced-lung-injury-via-some-antioxidants
#16
Mai O Kadry, Hanaa Mahmoud Ali
The aim of the current study is to evaluate the efficacy of pretreatment with either l-arginine (L-arg) or Carnosine (Car) and their combination in ameliorating some of the biochemical indices induced in the lung of sodium nitrite (NaNO2 )-intoxicated rats. The results revealed that NaNO2 significantly increased serum tumor necrosis factor-α, C-reactive protein, heat shock proteins-70, vascular endothelial growth factor, and Interleukin 6. Moreover, transforming growth factor-β, hypoxia-inducible factor, Smad-2, Protein Kinase B (AKT), and Bax were overexpressed, whereas Bcl2 protein was downregulated compared with the normoxic group...
March 7, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28231161/food-leftover-practices-among-consumers-in-selected-countries-in-europe-south-and-north-america
#17
Kadri Koppel, Federica Higa, Sandria Godwin, Nelson Gutierrez, Roman Shalimov, Paula Cardinal, Brizio Di Donfrancesco, Miriam Sosa, Angel A Carbonell-Barrachina, Loreida Timberg, Edgar Chambers
Foodborne illnesses may be related to many food production factors with home practices of consumers playing an important role in food safety. Consumer behavior for handling food leftovers has been studied, however little work on comparisons among countries has been published. The objective of this study was to investigate home food leftover practices of people from North American, South American, and European countries. Surveys were conducted with approximately 100 or more consumers in Argentina, Colombia, the United States, Estonia, Italy, Russia, and Spain...
September 21, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28225919/claudin-3-and-occludin-content-in-the-glands-of-colonic-mucosa-devoid-from-fecal-stream-submitted-to-topical-intervention-with-oil-extract-of-curcuma-longa
#18
Carlos Augusto Real Martinez, Caled Jaoudat Kadri, Danilo Toshio Kanno, Antônio José Tibúrcio Alves, Cláudio Saddy Rodrigues Coy, José Aires Pereira
Purpose: To evaluate the inflammatory intensity and measure the tissue content of the proteins claudin-3 and occludin in the colonic mucosa without fecal stream submit to intervention with curcumin. Methods: Thirty-six rats were submitted to a proximal colostomy and a distal mucous fistula and divided into two groups according to sacrifice to be performed two or four weeks. Each group was divided into three subgroups according daily application of enemas containing saline, curcumin at 50 mg/kg/day or 200 mg/kg/day...
January 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28224964/-horton-disease-in-the-elderly-patient
#19
REVIEW
Abrar-Ahmad Zulfiqar, Audrey Fouqué, Xavier Sui Seng, Nadir Kadri, Jean Doucet
Horton disease is difficult to diagnose in the elderly, due to the non-specificity of clinical signs. When evoked in the case of recent headaches, laboratory tests must be carried out to look for signs of inflammation.
January 2017: Soins. Gérontologie
https://www.readbyqxmd.com/read/28215969/focal-photodynamic-intracellular-acidification-as-a-cancer-therapeutic
#20
REVIEW
Matthew J Gdovin, Nuha Kadri, Lourdes Rios, Steven Holliday, Zachary Jordan
Cancer cells utilize an array of proton transporters to regulate intra- and extracellular pH to thrive in hypoxic conditions, and to increase tumor growth and metastasis. Efforts to target many of the transporters involved in cancer cell pH regulation have yielded promising results, however, many productive attempts to disrupt pH regulation appear to be non-specific to cancer cells, and more effective in some cancer cells than others. Following a review of the status of photodynamic cancer therapy, a novel light-activated process is presented which creates very focal, rapid, and significant decreases in only intracellular pH (pHi), leading to cell death...
February 12, 2017: Seminars in Cancer Biology
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