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https://www.readbyqxmd.com/read/28207639/predictors-of-waitlist-mortality-in-portopulmonary-hypertension
#1
Hilary M DuBrock, David S Goldberg, Norman L Sussman, Sonja D Bartolome, Zakiyah Kadry, Reena J Salgia, David C Mulligan, Walter K Kremers, Steven M Kawut, Michael J Krowka, Richard N Channick
BACKGROUND: The current Organ Procurement Transplantation Network (OPTN) policy grants Model for End Stage Liver Disease (MELD) exception points to patients with portopulmonary hypertension (POPH), but potentially important factors, such as severity of liver disease and pulmonary hypertension, are not included in the exception score, and may affect survival. The purpose of this study was to identify significant predictors of waitlist mortality in patients with POPH. METHODS: We performed a retrospective cohort study of patients in the OPTN database with hemodynamics consistent with POPH [defined as mean pulmonary arterial pressure (mPAP) >25mmHg and pulmonary vascular resistance (PVR) ≥240 dynes-s-cm] who were approved for a POPH MELD exception between 2006 and 2014...
February 15, 2017: Transplantation
https://www.readbyqxmd.com/read/28203640/tsunami-mitigation-by-resonant-triad-interaction-with-acoustic-gravity-waves
#2
Usama Kadri
Tsunamis have been responsible for the loss of almost a half million lives, widespread long lasting destruction, profound environmental effects, and global financial crisis, within the last two decades. The main tsunami properties that determine the size of impact at the shoreline are its wavelength and amplitude in the ocean. Here, we show that it is in principle possible to reduce the amplitude of a tsunami, and redistribute its energy over a larger space, through forcing it to interact with resonating acoustic-gravity waves...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28195547/phenolic-compounds-from-citrus-leaves-antioxidant-activity-and-enzymatic-browning-inhibition
#3
Bachra Khettal, Nabil Kadri, Karim Tighilet, Ahmed Adjebli, Farid Dahmoune, Fadila Maiza-Benabdeslam
Background Phenolic compounds from Citrus are known to be a topic of many studies due to their biological properties including antioxidant activity. Methods Methanolic and aqueous extracts were isolated from Citrus leaves of different species (C. clementina, C. limon, C. hamlin, C. navel, C. aurantifolia, C. aurantium and C. grandis) harvested in Algeria. Results The results showed that aqueous extracts of all species are rich in total phenolic compounds and flavonoids (from 68.23 to 125.28 mg GAE/g DM) and (from 11...
February 14, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28182248/coadministration-of-proton-pump-inhibitors-and-the-efficacy-of-capecitabine-in-patients-with-advanced-adenocarcinoma-of-the-small-bowel-or-ampulla-of-vater
#4
https://www.readbyqxmd.com/read/28157385/enhanced-s100a9-and-s100a12-expression-in-acute-coronary-syndrome
#5
Zafer Buyukterzi, Ummugulsum Can, Sertac Alpaydin, Asuman Guzelant, Sukru Karaarslan, Duygu Kocyigit, Kadri Murat Gurses
AIMS: In this study, we aimed to investigate whether serum S100A8, S100A9 and S100A12 levels were markers of acute coronary syndrome (ACS). MATERIALS & METHODS: Patients who underwent coronary angiography and/or percutaneous coronary interventions between June 2015-October 2015 were consecutively recruited in this study and categorized three groups each containing 30 patients (normal coronary arteries, stable coronary artery disease, and acute coronary syndrome)...
February 3, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28128450/experiences-in-microarray-based-evaluation-of-developmental-disabilities-and-congenital-anomalies
#6
Berk Ozyilmaz, Ozgür Kirbiyik, Altug Koc, Taha Resid Ozdemir, Ozge Ozer Kaya, Merve Saka Guvenc, Kadri Murat Erdoğan, Yasar Bekir Kutbay
Chromosomal microarray analysis is the as first-tier test for the evaluation of developmental disabilities and congenital anomalies. In this report, we present CMA results of 971 patient and 301 parent samples. Among 971 patient samples, 133 (13,6%) had pathogenic variants. While analyzing, an "in-house" variant database was also used besides other databases. Owing to this, we have found chance to report the most frequent benign variants in Turkish population. With the additional data we acqured in this study, we also emphasized the high potential of CMA in revealing single gene disorders and novel gene-phenotype associations as well as copy number variations...
January 27, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28120284/prevalence-of-fecal-incontinence-and-associated-risk-factors-in-elderly-outpatients-a-cross-sectional-study
#7
Nurhan Demir, Mehmet Yuruyen, Kadri Atay, Hakan Yavuzer, Ibrahim Hatemi, Alper Doventas, Deniz Suna Erdincler, Ahmet Dobrucalı
BACKGROUND: Data on the prevalence of fecal incontinence in elderly patients admitted to outpatient clinics in Turkey are scarce. AIMS: The aim of this study was to assess the prevalence of fecal incontinence and the associated risk factors in the elderly outpatients. METHODS: Patients 60 years and older admitted to a geriatrics outpatient clinic between October 2013 and March 2014 were included. Demographic characteristics, anthropometric measurements, marital status, educational status, parity (for females), fecal incontinence (FI), urinary incontinence (UI), constipation, comorbid conditions, and medications were recorded...
January 24, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28115806/a-novel-marker-of-impaired-aortic-elasticity-in-never-treated-hypertensive-patients-monocyte-high-density-lipoprotein-cholesterol-ratio
#8
Kadriye Gayretli Yayla, Uğur Canpolat, Çagri Yayla, Mehmet Kadri Akboğa, Ahmet Akyel, Ahmet Akdi, Gökhan Çiçek, Firat Ozcan, Osman Turak, Sinan Aydoğdu
BACKGROUND: Monocyte to high density lipoprotein cholesterol ratio (MHR) is generally understood to be a candidate marker of inflammation and oxidative stress. Therefore, we aimed to assess the association between MHR and aortic elastic properties in hypertensive patients. METHODS: A total of 114 newly-diagnosed untreated patients with hypertension and 71 healthy subjects were enrolled. Aortic stiffness index, aortic strain and aortic distensibility were measured by using echocardiography...
January 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28115152/biodegradation-of-polycyclic-aromatic-hydrocarbons-pahs-by-fungal-enzymes-a-review
#9
REVIEW
Tayssir Kadri, Tarek Rouissi, Satinder Kaur Brar, Maximiliano Cledon, Saurabhjyoti Sarma, Mausam Verma
Polycyclic aromatic hydrocarbons (PAHs) are a large group of chemicals. They represent an important concern due to their widespread distribution in the environment, their resistance to biodegradation, their potential to bioaccumulate and their harmful effects. Several pilot treatments have been implemented to prevent economic consequences and deterioration of soil and water quality. As a promising option, fungal enzymes are regarded as a powerful choice for degradation of PAHs. Phanerochaete chrysosporium, Pleurotus ostreatus and Bjerkandera adusta are most commonly used for the degradation of such compounds due to their production of ligninolytic enzymes such as lignin peroxidase, manganese peroxidase and laccase...
January 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28112955/fate-of-eight-different-polymers-under-uncontrolled-composting-conditions-relationships-between-deterioration-biofilm-formation-and-the-material-surface-properties
#10
Anne Mercier, Kevin Gravouil, Willy Aucher, Sandra Brosset-Vincent, Linette Kadri, Jenny Colas, Didier Bouchon, Thierry Ferreira
With the ever-increasing volume of polymer wastes and their associated detrimental impacts on the environment, the plastic life-cycle has focused increasing attention. Here, eight commercial polymers selected from biodegradable to environmentally-persistent materials, all formulated under a credit card format, were incubated in an outdoor compost to evaluate their fate over time and to profile the microbial communities colonizing their surfaces. After 450 days in compost, the samples were all colonized by multispecies biofilms, these latest displaying different amounts of adhered microbial biomass and significantly distinct bacterial and fungal community compositions depending on the substrate...
January 23, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28106019/pulmonary-vein-anatomy-and-its-variations-in-a-turkish-atrial-fibrillation-cohort-undergoing-cryoballoon-based-catheter-ablation
#11
Duygu Koçyiğit, Kadri Murat Gürses, Muhammed Ulvi Yalçın, Gamze Türk, Banu Evranos, Uğur Canpolat, Hikmet Yorgun, Tuncay Hazırolan, Kudret Aytemir
OBJECTIVE: Pulmonary vein (PV) anatomy has drawn attention since assumption that atrial fibrillation (AF) may originate from PVs and that electrical isolation of PVs may be beneficial in eliminating these triggers. The present study aims to investigate PV anatomy and its variations in a sample of Turkish patients undergoing PV isolation (PVI) for AF. METHODS: 250 patients underwent multidetector computed tomography before cryoballoon-based PVI for AF. PV and left atrial (LA) anatomy were evaluated in 3-dimensional epicardial reconstructions...
January 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28081307/the-demographics-and-histopathological-features-of-oral-cavity-cancers-in-turkey
#12
Mehmet Düzlü, Recep Karamert, Faruk Kadri Bakkal, Raşit Cevizci, Hakan Tutar, Mehmet Ekrem Zorlu, Alper Dilci, Fakih Cihat Eravcı
BACKGROUND/AIM: This study aimed to examine the demographics and histopathological features of oral cavity cancers (OCCs) managed in our clinic. MATERIALS AND METHODS: Patients who were diagnosed with OCCs in the Gazi University Otorhinolaryngology Department between the years 1993 and 2013 were retrospectively enrolled in the study. Surgical archive charts and pathology records were reviewed in detail regarding the anatomical and histopathological profiles of the tumors, as well as the demographic data of the patients...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28079650/pneumatic-displacement-of-limited-traumatic-submacular-hemorrhage-without-tissue-plasminogen-activator-a-case-series
#13
Poornachandra Balughatta, Venkatesh Kadri, Sherine Braganza, Chaitra Jayadev, Ruchir A Mehta, Vikram Nakhate, Naresh K Yadav, Rohit Shetty
PURPOSE: To evaluate the efficacy of intravitreal gas (perfluoropropane, C3F8)-assisted displacement of submacular hemorrhage (SMH) secondary to recent or old blunt trauma. METHODS: An interventional case series of three patients who presented with SMH after blunt trauma, ranging from 2 days to 2 weeks back. All three patients were treated with an intravitreal injection of 0.3 cc of 100% C3F8 with anterior chamber paracentesis. Strict prone position was advised for 2 weeks with a minimum of 6 to 8 hours per day...
January 10, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28076832/dietary-supplementation-of-grape-seed-and-skin-flour-mitigates-brain-oxidative-damage-induced-by-a-high-fat-diet-in-rat-gender-dependency
#14
Kamel Charradi, Mohamed Mahmoudi, Takwa Bedhiafi, Safwen Kadri, Salem Elkahoui, Ferid Limam, Ezzedine Aouani
It is unknown whether gender has an impact on brain injury in obesity, and, if so, whether treatment with grape seed and skin flour could exert a protective effect. Both male and female rats were fed a standard diet (SD) or a high fat diet (HFD) during eight weeks and treated with high dosage grape seed and skin flour (GSSF). Fat-induced oxidative stress was evaluated into the brain with a special emphasis on transition metals determination. HFD induced male-cholesterol overload (+78.12%) and an oxidative stress status characterized by increased lipoperoxidation (+68...
January 8, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28074573/structural-functional-and-clinical-characterization-of-a-novel-ptpn11-mutation-cluster-underlying-noonan-syndrome
#15
Luca Pannone, Gianfranco Bocchinfuso, Elisabetta Flex, Cesare Rossi, Giuseppina Baldassarre, Christina Lissewski, Francesca Pantaleoni, Federica Consoli, Francesca Lepri, Monia Magliozzi, Massimiliano Anselmi, Giovanni Sorge, Kadri Karaer, Goran Cuturilo, Alessandro Sartorio, Sigrid Tinschert, Maria Accadia, Maria C Digilio, Giuseppe Zampino, Alessandro De Luca, Hélène Cavé, Martin Zenker, Bruce D Gelb, Bruno Dallapiccola, Lorenzo Stella, Giovanni B Ferrero, Simone Martinelli, Marco Tartaglia
Germline mutations in PTPN11, the gene encoding the Src-homology 2 (SH2) domain-containing protein tyrosine phosphatase (SHP2), cause Noonan syndrome (NS), a relatively common, clinically variable, multisystem disorder. Here, we report on the identification of five different PTPN11 missense changes affecting residues Leu(261) , Leu(262) and Arg(265) in 16 unrelated individuals with clinical diagnosis of NS or with features suggestive for this disorder, specifying a novel disease-causing mutation cluster. Expression of the mutant proteins in HEK293T cells documented their activating role on MAPK signaling...
January 10, 2017: Human Mutation
https://www.readbyqxmd.com/read/28053637/comment-to-patients-with-concordant-triple-negative-phenotype-between-primary-breast-cancers-and-corresponding-metastases-have-poor-prognosis
#16
COMMENT
Kadri Altundag
No abstract text is available yet for this article.
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28052428/palladium-catalyzed-cross-coupling-reactions-controlled-by-non-covalent-zn%C3%A2-n-interactions
#17
Rafael Gramage-Doria, Mohamed Kadri, Jingran Hou, Vincent Dorcet, Thierry Roisnel, Lazhar Bechki, Abdellah Miloudi, Christian Bruneau
Non-covalent interactions between halopyridine substrates and catalytically inert building blocks, namely zinc(II)-porphyrins and zinc(II)-salphens, influence the catalytic outcome of Suzuki-Miyaura and Mizoroki-Heck palladium-catalyzed cross-coupling reactions. The weak Zn…N interactions between halopyridine substrates and zinc(II)-containing porphyrins and salphens respectively, were studied by a combination of 1H NMR spectroscopy, UV-vis studies, Job-Plot analysis and, in some cases, X-ray diffraction studies...
January 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28045834/discussion-on-analysis-of-fractured-mandible-over-two-decades
#18
Kadri Ozer
No abstract text is available yet for this article.
December 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28039728/chemotherapy-and-loss-of-fingerprint-problematic-issue-beyond-the-side-effect
#19
Aras Mumyakmaz, Kadri Altundag
No abstract text is available yet for this article.
November 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28034881/impact-of-intravenous-immunoglobulin-on-survival-in-necrotizing-fasciitis-with-vasopressor-dependent-shock-a-propensity-score-matched-analysis-from-130-us-hospitals
#20
Sameer S Kadri, Bruce J Swihart, Stephanie L Bonne, Samuel F Hohmann, Laura V Hennessy, Peter Louras, Heather L Evans, Chanu Rhee, Anthony F Suffredini, David C Hooper, Dean A Follmann, Eileen Bulger, Robert L Danner
BACKGROUND: Shock frequently complicates necrotizing fasciitis (NF) caused by group A streptococcus (GAS) or Staphylococcus aureus (SA). Intravenous immunoglobulin (IVIG) is sometimes administered for presumptive toxic shock syndrome (TSS), but its frequency of use and efficacy are unclear. METHODS: Adult patients with NF and vasopressor-dependent shock undergoing surgical debridement from 2010 to 2014 were identified at 130 U.S. hospitals. IVIG cases were propensity-matched and risk-adjusted...
December 29, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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