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https://www.readbyqxmd.com/read/29667231/feasibility-and-clinical-outcomes-of-rotational-atherectomy-for-heavily-calcified-side-branches-of-complex-coronary-bifurcation-lesions-in-the-real-world-practice-of-the-drug-eluting-stent-era
#1
Yu-Wei Chen, Chieh-Shou Su, Wei-Chun Chang, Tsun-Jui Liu, Kae-Woei Liang, Chih-Hung Lai, Hong-Xu Liu, Wen-Lieng Lee
OBJECTIVES: To evaluate the outcomes of rotational atherectomy for heavily-calcified side branches of coronary bifurcation lesions. BACKGROUND: Side-branch (SB) preservation is clinically important but technically challenging in heavily-calcified non-left main true bifurcation lesions. SB rotational atherectomy (SB RA) is sometimes mandatory but the clinical outcomes are not well studied. METHODS: We retrospectively studied the outcomes of patients who underwent RA at our institute for heavily calcified, balloon-uncrossable or-undilatable SB lesions over an approximately 5-year period (January 2011 to September 2016)...
April 17, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29667015/stent-thrombosis-rates-the-first-year-and-beyond-with-new-and-old-generation-drug-eluting-stents-compared-to-bare-metal-stents
#2
Christoph Varenhorst, Martin Lindholm, Giovanna Sarno, Göran Olivecrona, Ulf Jensen, Johan Nilsson, Jörg Carlsson, Stefan James, Bo Lagerqvist
OBJECTIVES: Old-generation drug-eluting coronary stents (o-DES) have despite being safe and effective been associated with an increased propensity of late stent thrombosis (ST). We evaluated ST rates in o-DES, new-generation DES (n-DES) and bare metal stents (BMS) the first year (< 1 year) and beyond 1 year (> 1 year). METHODS: We evaluated all implantations with BMS, o-DES (Cordis Cypher, Boston Scientific Taxus Liberté and Medtronic Endeavor) and n-DES in the Swedish coronary angiography and angioplasty registry (SCAAR) between 1 January 2007 and 8 January 2014 (n = 207 291)...
April 17, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29666900/polymer-free-biolimus-a9-coated-stent-for-primary-percutaneous-coronary-intervention
#3
D J H Lee, J K K Loh, F H Jafary, H H Ho, T Watson, H-P Stoll, P J L Ong
BACKGROUND: The polymer-free biolimus-A9 drug-coated stent (DCS) was reported to have superior safety and efficacy outcomes compared with a bare metal stent in the LEADERS FREE trial of high-bleeding-risk patients with acute coronary syndrome and on dual antiplatelet treatment (DAPT) for 1 month. The aim of this investigation was to evaluate the DCS in a consecutive cohort of patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI)...
April 17, 2018: Herz
https://www.readbyqxmd.com/read/29666071/b-type-natriuretic-peptide-assessment-in-patients-undergoing-revascularization-for-left-main-coronary-artery-disease-analysis-from-the-excel-trial
#4
Björn Redfors, Shmuel Chen, Aaron Crowley, Ori Ben-Yehuda, Bernard J Gersh, Nicholas J Lembo, W Morris Brown, Adrian P Banning, David P Taggart, Patrick W Serruys, Arie Pieter Kappetein, Joseph F Sabik, Gregg W Stone
Background -Elevated B-type natriuretic peptide (BNP) is reflective of impaired cardiac function and is associated with worse prognosis among patients with coronary artery disease (CAD). We sought to assess the association between baseline BNP, adverse outcomes, and the relative efficacy of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) in patients with left main (LM) CAD. Methods -The EXCEL trial randomized patients with LMCAD and low or intermediate SYNTAX scores to PCI with everolimus-eluting stents versus CABG...
April 17, 2018: Circulation
https://www.readbyqxmd.com/read/29663443/time-trends-in-antithrombotic-management-of-patients-with-atrial-fibrillation-treated-with-coronary-stents-results-from-talent-af-the-international-stent-atrial-fibrillation-study-multicenter-registry
#5
Brian J Potter, Giuseppe Andò, Giovanni Cimmino, Ricardo Ladeiras-Lopes, Zied Frikah, Xin Yue Chen, Vittorio Virga, Joao Goncalves-Almeida, A John Camm, Keith A A Fox
BACKGROUND: Antithrombotic management of patients with atrial fibrillation (AF) requiring percutaneous coronary intervention (PCI) is highly variable; limited evidence-based guidelines exist to influence practice. HYPOTHESIS: Patient characteristics and availability of novel drugs may have contributed to practice variability. METHODS: We undertook an international multicenter retrospective registry of AF patients treated with PCI. The primary measures of interest were antiplatelet and OAC prescriptions at discharge...
April 17, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29663177/intravascular-ultrasound-assessment-of-the-effects-of-rotational-atherectomy-in-calcified-coronary-artery-lesions
#6
Sung Sik Kim, Myong Hwa Yamamoto, Akiko Maehara, Novalia Sidik, Kohei Koyama, Colin Berry, Keith G Oldroyd, Gary S Mintz, Margaret McEntegart
We sought to clarify intravascular ultrasound (IVUS) features of rotational atherectomy (RA) of calcified lesions. IVUS was performed post-RA and post-stent in 38 lesions and analyzed every 1 mm. Pre-intervention IVUS was performed when the IVUS catheter crossed the lesion (n = 11). Calcium Index was average calcium angle multiplied by calcium length. We compared lowest (n = 13), middle (n = 13), and highest (n = 12) Calcium Index tertiles. Reverberations (multiple reflections from calcium) with a concave-shaped lumen in the post-RA IVUS were considered to represent RA-related calcium modification...
April 16, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29662511/treatment-of-coronary-in-stent-restenosis-a-systematic-review
#7
REVIEW
Leos Pleva, Pavel Kukla, Ota Hlinomaz
Coronary stent implantation has significantly improved percutaneous coronary intervention and enabled the management of early complications of plain balloon angioplasty. However, a new complication has accompanied these improvements: in-stent restenosis (ISR) arising from neointimal hyperplasia. ISR after coronary angioplasty is currently one of the main limitations of this method, leading to the recurrence of exertional angina pectoris or acute coronary syndromes. The clinical incidence of ISR after bare-metal stent (BMS) implantation is approximately 20%-35%...
February 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29662510/long-term-outcomes-of-drug-eluting-stent-versus-coronary-artery-bypass-grafting-for-left-main-coronary-artery-disease-a-meta-analysis
#8
Kong-Yong Cui, Shu-Zheng Lyu, Xian-Tao Song, Fei Yuan, Feng Xu, Min Zhang, Ming-Duo Zhang, Wei Wang, Dong-Feng Zhang, Jing Dai, Jin-Fan Tian, Yun-Lu Wang
Background: It is still controversial whether percutaneous coronary intervention with drug-eluting stent (DES) is safe and effective compared to coronary artery bypass graft surgery (CABG) for unprotected left main coronary artery (ULMCA) disease at long-term follow up (≥ 3 years). Methods: Eligible studies were selected by searching PubMed, EMBASE, and Cochrane Library up to December 6, 2016. The primary endpoint was a composite of death, myocardial infarction (MI) or stroke during the longest follow-up...
February 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29662508/obstructive-sleep-apnea-is-associated-with-severity-and-long-term-prognosis-of-acute-coronary-syndrome
#9
Shuo Jia, Yu-Jie Zhou, Yi Yu, Si-Jing Wu, Yan Sun, Zhi-Jian Wang, Xiao-Li Liu, Bright Eric King, Ying-Xin Zhao, Dong-Mei Shi, Yu-Yang Liu, Zhi-Ming Zhou
Background: Obstructive sleep apnea (OSA) is a common disease in patients with acute coronary syndrome (ACS) and associated with an increased risk of fatal and nonfatal cardiovascular events. However, most patients in previous study were treated with bare metal stents and the sample sizes were relatively low. The goal of this study was to evaluate the influence of OSA on the severity and prognosis of patients admitted for ACS. Methods: In this prospective cohort study, we enrolled patients with ACS who were hospitalized for coronary angiogram/percutaneous coronary intervention and undergone polysomnography...
February 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29662507/new-predictors-of-in-stent-restenosis-in-patients-with-diabetes-mellitus-undergoing-percutaneous-coronary-intervention-with-drug-eluting-stent
#10
Jian-Long Wang, Zheng Qin, Zhi-Jian Wang, Dong-Mei Shi, Yu-Yang Liu, Ying-Xin Zhao, Li-Xia Yang, Wan-Jun Cheng, Yu-Jie Zhou
Background: Percutaneous coronary intervention (PCI) had become the major therapeutic procedure for coronary artery disease (CAD), but the high rate of in-stent restenosis (ISR) still remained an unsolved clinical problem in clinical practice. Increasing evidences suggested that diabetes mellitus (DM) was a major risk factor for ISR, but the risk predictors of ISR in CAD patients with DM had not been well characterized. The aim of this study was to investigate the clinical and angiographic characteristic predictors significantly associated with the occurrence of ISR in diabetic patients following coronary stenting with drug-eluting stent (DES)...
February 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29662504/comparison-of-the-safety-and-efficacy-of-two-types-of-drug-eluting-balloons-restore-deb-and-sequent-%C3%A2-please-in-the-treatment-of-coronary-in-stent-restenosis-study-protocol-for-a-randomized-controlled-trial-restore-isr-china
#11
Lei Gao, Qin Qin, Shao-Liang Chen, Hui Chen, Le-Feng Wang, Ze-Ning Jin, Hui Li, Jun Zhang, Jian-An Wang, Yang Zheng, Guo-Sheng Fu, Yun-Dai Chen
No abstract text is available yet for this article.
February 2018: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29661597/clinical-performance-of-a-dedicated-self-apposing-stent-for-the-treatment-of-left-main-stem-disease-results-of-the-left-main-angioplasty-with-a-self-apposing-stent-the-matisse-study
#12
Bernardo Cortese, Antonio Montefusco, Fabrizio D'Ascenzo, Alessio La Manna, Giuseppe Andò, Teodoro Bisceglia, Gioel G Secco, Markus Meyer-Gessner, Wanha Wojciech, Paolo Sganzerla, Massimo Napodano, Gaetano Di Palma, Roberto A Latini, Corrado Tamburino, Pedro Silva Orrego, Andreas Baumbach
BACKGROUND: In the recent years percutaneous treatment of the left main stem (LM) has gained a precise role as a result of consistent scientific evidence vs. coronary artery bypass. A self-apposing stent offers an improved adaptation to the vessel wall, especially in case of tapered vessels; aim of this study was to investigate the role of a novel self-apposing, sirolimus-eluting stent (Stentys, France) for the treatment of LM coronary artery disease. METHODS AND RESULTS: MATISSE is a retrospective, multicenter registry, which enrolled 151 patients treated with the device at 17 international centers...
April 4, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29661401/erratum-to-management-of-antiplatelet-therapy-in-patients-with-coronary-stents-undergoing-noncardiac-surgery-association-with-adverse-events-br-j-anaesth-2018-120-67-76
#13
A Rodriguez, N Guilera, A Mases, P Sierra, J C Oliva, C Colilles
No abstract text is available yet for this article.
May 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29661004/percutaneous-versus-surgical-revascularization-for-left-main-or-multivessel-coronary-artery-disease-results-from-a-large-scale-meta-analysis-in-the-era-of-drug-eluting-stents
#14
Monica Verdoia, Lucia Barbieri, Elvin Kedhi, Harry Suryapranata, Giuseppe De Luca
The best treatment options for left main (LM) or multivessel coronary disease (MVD) are still debated. We performed a meta-analysis of randomized trials comparing percutaneous versus surgical revascularization for LM or MVD. Primary end point was overall mortality. Secondary end points were major adverse cardiovascular events, recurrent myocardial infarction, repeated revascularization, or stroke. A total of 8 randomized trials were included, involving 8694 patients, 50% undergoing percutaneous coronary intervention (PCI)...
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29660352/outcomes-in-a-community-based-intensive-cardiac-rehabilitation-program
#15
Charles Katzenberg, Edna Silva, M Jean Young, Greg Gilles
PURPOSE: The purpose of this study was to test the hypothesis that a community-based Intensive Cardiac Rehabilitation Program could produce positive changes in risk factor profile and outcomes in an at-risk population. METHODS: Participants seeking either primary or secondary coronary artery disease prevention voluntarily enrolled in the 12 week Intensive Cardiac Rehabilitation Program. Data were obtained at baseline and 6-12 months after completion of the program...
April 13, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29658862/progress-in-gene-therapy-for-chronic-heart-failure
#16
Zhi-Qiang Yin, Wan-Hong Xing
Chronic heart failure (CHF) is still the leading cause of morbidity and mortality worldwide, and carries with it large economic and social burdens. Although steady and substantial progress has been made in reducing mortality from heart failure using conventional treatments, novel pharmacologic and surgical interventions have not been effective in extending five year survival rates. Therefore, it is necessary to explore new therapies. Gene therapy was introduced in 1970s with the development of recombinant DNA technology...
March 5, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29656938/vitamin-d-deficiency-and-periprocedural-myocardial-infarction-in-patients-undergoing-percutaneous-coronary-interventions
#17
Monica Verdoia, Claudia Ceccon, Matteo Nardin, Harry Suryapranata, Giuseppe De Luca
Vitamin D deficiency has been implicated in the progression of atherosclerosis and acute thrombotic events. We aimed at evaluating the impact of vitamin D deficiency on periprocedural myocardial infarction (PMI) in patients undergoing percutaneous coronary interventions (PCI). We included 934 patients undergoing non-urgent PCI. Assessment of myocardial biomarkers was performed from 6 to 48 h after PCI. PMI was defined as Creatine Kinase-MB increase by 3 times the Upper Limit Normal or by 50% of an elevated baseline value, periprocedural myocardial damage as Troponin I increase by 3 × ULN or 50% of baseline...
March 4, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29656281/treatment-of-very-small-de-novo-coronary-artery-disease-with-2-0-mm-drug-coated-balloons-showed-1-year-clinical-outcome-comparable-with-2-0-mm-drug-eluting-stents
#18
Hui Wen Sim, Rajiv Ananthakrishna, Siew Pang Chan, Adrian F Low, Chi-Hang Lee, Mark Y Chan, Edgar L Tay, Poay Huan Loh, Koo Hui Chan, Huay Cheem Tan, Joshua P Loh
OBJECTIVE: To evaluate the 1-year clinical outcomes of patients treated with 2.0 mm drug-coated balloon (DCB) vs 2.0 mm drug-eluting stent (DES) implantation in small-caliber vessel de novo coronary artery disease (CAD). METHODS: All patients treated with 2.0 mm DCB or 2.0 mm DES for very small vessel de novo CAD from July 2014 to June 2016 were included in this study. The primary endpoint was the occurrence of target-lesion failure (TLF) and time to TLF, defined as a combination of cardiac mortality, target-vessel myocardial infarction, and target-lesion revascularization (TLR)...
April 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29656280/real-world-bioresorbable-vascular-scaffold-experience-compared-with-second-generation-metallic-drug-eluting-stents-in-complex-coronary-lesions
#19
Naotaka Okamoto, Hiroshi Ueda, Takahiro Yoshimura, Surbhi Chamaria, Samit Bhatheja, Yuliya Vengrenyuk, Samaneh Rabiei, Yonandy Barrientos, Vishal Kapur, Nitin Barman, Joseph Sweeny, Usman Baber, Roxana Mehran, Samin K Sharma, Annapoorna S Kini
OBJECTIVES: The aim of the study was to compare the acute outcomes of Absorb bioresorbable vascular scaffolds (BVS) and second-generation drug-eluting stent (DES) implantation in routine clinical practice. There is a paucity of data regarding BVS use in a real-world patient population. METHODS: The study population comprised 40 consecutive patients who underwent percutaneous coronary intervention (PCI) with BVS implantation at a tertiary-care center in New York, New York between July and December of 2016...
April 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29656120/systemic-inflammatory-response-syndromes-in-the-era-of-interventional-cardiology
#20
REVIEW
Riccardo Gorla, Raimund Erbel, Kim A Eagle, Eduardo Bossone
Systemic inflammatory response syndrome (SIRS), initially reported after cardiovascular surgery, has been described after various interventional cardiology procedures, including endovascular/thoracic aortic repair (EVAR/TEVAR), implantation of heart rhythm devices, percutaneous coronary intervention (PCI), electrophysiology procedures (EP), and transcatheter aortic valve implantation (TAVI). In these settings, a comprehensive understanding of the triggers, pathogenesis as well as a common diagnostic/therapeutic algorithm is lacking and will be discussed in this review...
April 12, 2018: Vascular Pharmacology
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