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https://www.readbyqxmd.com/read/28097430/how-i-do-it-the-mononostril-endonasal-transethmoidal-paraseptal-approach
#1
Robert Reisch, Hans Rudolf Briner, Anne-Katrin Hickmann
BACKGROUND: The use of endoscopes in transnasal surgery offers increased visualization. To minimize rhinological morbidity without restriction in manipulation, we introduced the mononostril transethmoidal-paraseptal approach. METHODS: The aim of the transethmoidal-paraseptal approach is to create sufficient space within the nasal cavity, without removal of nasal turbinates and septum. Therefore, as a first step, a partial ethmoidectomy is performed. The middle and superior turbinates are then lateralized into the ethmoidal space, allowing a wide sphenoidotomy with exposure of the central skull base...
January 18, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28096507/de-novo-phosphorylation-and-conformational-opening-of-the-tyrosine-kinase-lck-act-in-concert-to-initiate-t-cell-receptor-signaling
#2
Lars Philipsen, Amarendra V Reddycherla, Roland Hartig, Janine Gumz, Matthias Kästle, Andreas Kritikos, Mateusz P Poltorak, Yury Prokazov, Evgeny Turbin, André Weber, Werner Zuschratter, Burkhart Schraven, Luca Simeoni, Andreas J Müller
The enzymatic activity of the Src family tyrosine kinase p56(Lck) (Lck) is tightly controlled by differential phosphorylation of two tyrosine residues, Tyr(394) and Tyr(505) Phosphorylation of Tyr(394) and the conformational opening of Lck are believed to activate the kinase, whereas Tyr(505) phosphorylation is thought to generate a closed, inactive conformation of Lck. We investigated whether the conformation of Lck and its phosphorylation state act in concert to regulate the initiation of T cell receptor (TCR) signaling...
January 17, 2017: Science Signaling
https://www.readbyqxmd.com/read/28070246/commentary-on-evaluation-of-variations-in-sinonasal-region-with-computed-tomography
#3
Can A Çağıcı
This letter is a commentary on the article titled "Evaluation of variations in sinonasal region with computed tomography", published in the January 2016 issue of World Journal of Radiology. The authors definition of the secondary middle turbinate is incorrect. The authors stated that the secondary middle turbinate is an accessory turbinate that is seen between the superior and middle turbinates. It should originate from the middle meatus posterosuperior to the ethmoid infundibulum.
December 28, 2016: World Journal of Radiology
https://www.readbyqxmd.com/read/28062112/a-modelling-framework-to-predict-bat-activity-patterns-on-wind-farms-an-outline-of-possible-applications-on-mountain-ridges-of-north-portugal
#4
Carmen Silva, João Alexandre Cabral, Samantha Jane Hughes, Mário Santos
Worldwide ecological impact assessments of wind farms have gathered relevant information on bat activity patterns. Since conventional bat study methods require intensive field work, the prediction of bat activity might prove useful by anticipating activity patterns and estimating attractiveness concomitant with the wind farm location. A novel framework was developed, based on the stochastic dynamic methodology (StDM) principles, to predict bat activity on mountain ridges with wind farms. We illustrate the framework application using regional data from North Portugal by merging information from several environmental monitoring programmes associated with diverse wind energy facilities that enable integrating the multifactorial influences of meteorological conditions, land cover and geographical variables on bat activity patterns...
January 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28059551/wnt-signaling-in-chronic-rhinosinusitis-with-nasal-polyps
#5
Robert Böscke, Eszter K Vladar, Michael Könnecke, Birgit Hüsing, Robert Linke, Ralph Pries, Norbert Reiling, Jeffrey D Axelrod, Jayakar V Nayak, Barbara Wollenberg
The signaling pathways that sustain the disease process of chronic rhinosinusitis with nasal polyps (CRSwNP) remain poorly understood. We sought to determine the expression levels of Wnt signaling genes in CRSwNP, and to study the role of the Wnt pathway in inflammation and epithelial remodeling in the nasal mucosa. Microarrays and RT-qPCR comparing gene expression in matched nasal polyps (NP) and inferior turbinates (IT) revealed that WNT2B, WNT3A, WNT4, WNT7A, WNT7B and FZD2 were upregulated, and FZD1, LRP5, LRP6 and WIF1 downregulated in NPs...
January 6, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28055198/gas-turbine-engine-nonvolatile-particulate-matter-mass-emissions-correlation-with-smoke-number-for-conventional-and-alternative-fuel-blends
#6
Simon Christie, Prem Lobo, David Lee, David Raper
This study evaluates the relationship between the emissions parameters of smoke number (SN) and mass concentration of nonvolatile particulate matter (nvPM) in the exhaust of a gas turbine engine for a conventional Jet A-1 and a number of alternative fuel blends. The data demonstrate the significant impact of fuel composition on the emissions and highlight the magnitude of the fuel-induced uncertainty for both SN within the Emissions Data Bank as well as nvPM mass within the new regulatory standard under development...
January 5, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28052420/a-novel-approach-to-brachycephalic-syndrome-3-isolated-laser-assisted-turbinectomy-of-caudal-aberrant-turbinates-cat-late
#7
Riccarda Schuenemann, Sabine Pohl, Gerhard U Oechtering
OBJECTIVE: To describe isolated laser-assisted turbinectomy of caudal aberrant turbinates (CAT LATE) as a new minimally invasive surgical procedure for the treatment of brachycephalic dogs with obstructing caudal aberrant turbinates (CAT). STUDY DESIGN: Prospective clinical study. ANIMALS: Brachycephalic dogs (24 Pugs, 1 English Bulldog) with CAT but adequate air spaces between the lamellae of the nonobstructing ventral nasal concha. METHODS: A rhinoscopically guided diode laser fiber introduced from anterior was used to dissect CAT within the nasopharyngeal meatus, while leaving the intranasal turbinates intact...
January 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28051241/effects-of-omalizumab-therapy-on-allergic-rhinitis-a-pilot-study
#8
S Masieri, C Cavaliere, E Begvarfaj, D Rosati, A Minni
OBJECTIVE: The use of omalizumab, a humanized monoclonal antibody able to binding Ig-E, is currently authorized only for treatment of severe bronchial asthma. The use of omalizumab in other Ig-E related diseases is off-label, although some studies have provided promising results about it. The aim of this study was to evaluate if therapy with omalizumab in patients affected by asthma and allergic rhinitis has an impact also on allergic rhinitis-related symptoms. PATIENTS AND METHODS: A longitudinal study was conducted on 11 patients affected by severe asthma and a periodic allergic rhinitis...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28049313/thermodynamics-of-supersaturated-steam-molecular-simulation-results
#9
Filip Moučka, Ivo Nezbeda
Supersaturated steam modeled by the Gaussian charge polarizable model [P. Paricaud, M. Předota, and A. A. Chialvo, J. Chem. Phys. 122, 244511 (2005)] and BK3 model [P. Kiss and A. Baranyai, J. Chem. Phys. 138, 204507 (2013)] has been simulated at conditions occurring in steam turbines using the multiple-particle-move Monte Carlo for both the homogeneous phase and also implemented for the Gibbs ensemble Monte Carlo molecular simulation methods. Because of these thermodynamic conditions, a specific simulation algorithm has been developed to bypass common simulation problems resulting from very low densities of steam and cluster formation therein...
December 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28040589/production-of-demineralized-water-for-use-in-thermal-power-stations-by-advanced-treatment-of-secondary-wastewater-effluent
#10
Ioannis A Katsoyiannis, Petros Gkotsis, Massimo Castellana, Fabricio Cartechini, Anastasios I Zouboulis
The operation and efficiency of a modern, high-tech industrial full-scale water treatment plant was investigated in the present study. The treated water was used for the supply of the boilers, producing steam to feed the steam turbine of the power station. The inlet water was the effluent of municipal wastewater treatment plant of the city of Bari (Italy). The treatment stages comprised (1) coagulation, using ferric chloride, (2) lime softening, (3) powdered activated carbon, all dosed in a sedimentation tank...
December 29, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/28038674/construction-of-a-molecular-clone-of-ovine-enzootic-nasal-tumor-virus
#11
Scott R Walsh, María Carla Rosales Gerpe, Sarah K Wootton
BACKGROUND: Enzootic nasal tumor virus (ENTV-1) is an ovine betaretrovirus that has been linked to enzootic nasal adenocarcinoma (ENA), a contagious tumor of the ethmoid turbinates of sheep. Transmission experiments performed using virus isolated from cell free nasal tumor homogenates suggest that ENTV-1 is the causative agent of ENA; however, this etiological relationship has not been conclusively proven due to the fact that the virus cannot be propagated in vitro nor is there an infectious molecular clone of the virus...
December 30, 2016: Virology Journal
https://www.readbyqxmd.com/read/28032162/a-practical-technique-for-reduction-of-the-bony-nasal-dorsum-height-using-kazanjian-bone-cutting-forceps
#12
Yalcin Yontar, Sedat Tatar
BACKGROUND: Resection of the nasal hump is one of the most critical steps of the rhinoplasty procedure, which is quite prone to complications when performed improperly or inappropriately. In this article, a practical, facile and minimally traumatic hump resection technique using Kazanjian bone-cutting forceps is presented with excellent cosmetic and functional results. METHODS: Fifty-seven consecutive primary (septo-)rhinoplasty patients with wide nasal bases, and various sizes of nasal humps, were enrolled in the study...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28028486/effects-of-wind-energy-generation-and-white-nose-syndrome-on-the-viability-of-the-indiana-bat
#13
Richard A Erickson, Wayne E Thogmartin, Jay E Diffendorfer, Robin E Russell, Jennifer A Szymanski
Wind energy generation holds the potential to adversely affect wildlife populations. Species-wide effects are difficult to study and few, if any, studies examine effects of wind energy generation on any species across its entire range. One species that may be affected by wind energy generation is the endangered Indiana bat (Myotis sodalis), which is found in the eastern and midwestern United States. In addition to mortality from wind energy generation, the species also faces range-wide threats from the emerging infectious fungal disease, white-nose syndrome (WNS)...
2016: PeerJ
https://www.readbyqxmd.com/read/28027245/intranasal-pathology-in-the-migraine-surgery-population-incidence-patterns-and-predictors-of-surgical-success
#14
Michelle Lee, Cameron Erickson, Bahman Guyuron
BACKGROUND: The purpose of this study was to identify patterns of nasal pathology in patients with rhinogenic migraine headaches (site III). METHODS: A retrospective review was performed on patients with rhinogenic migraine headaches. Demographics, pre- and post-migraine surgery symptoms, and pathology seen on preoperative computed tomographic scans were reviewed. RESULTS: Twenty percent of 98 patients had preoperative sinus disease. The following abnormalities were seen on computed tomographic scan: septal deviation, 75 (77 percent); septal spur, 33 (34 percent); middle concha bullosa, 48 (49 percent); sinus pathology, 20 (20 percent); and intranasal contact points, 62 (62 percent)...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28026837/trigeminal-sensitivity-in-chronic-rhinosinusitis-topographical-di-erences-and-the-e-ect-of-surgery
#15
S C Poletti, M Cuevas, S Weile, T Hummel
INTRODUCTION: Little is known on endonasal trigeminal sensitivity in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). The aim of our study was to investigate changes in trigeminal sensitivity in patients with CRSwNP and the effect of functional endoscopic sinus surgery (FESS) on trigeminal perception. METHODS: A prospective study was performed to investigate the trigeminal sensitivity at three different locations within the nose (anterior septum, anterior lateral wall, middle turbinate) using electrical stimuli...
December 27, 2016: Rhinology
https://www.readbyqxmd.com/read/28018798/exact-solutions-for-unsteady-free-convection-flow-over-an-oscillating-plate-due-to-non-coaxial-rotation
#16
Ahmad Qushairi Mohamad, Ilyas Khan, Zulkhibri Ismail, Sharidan Shafie
BACKGROUND: Non-coaxial rotation has wide applications in engineering devices, e.g. in food processing such as mixer machines and stirrers with a two-axis kneader, in cooling turbine blades, jet engines, pumps and vacuum cleaners, in designing thermal syphon tubes, and in geophysical flows. Therefore, this study aims to investigate unsteady free convection flow of viscous fluid due to non-coaxial rotation and fluid at infinity over an oscillating vertical plate with constant wall temperature...
2016: SpringerPlus
https://www.readbyqxmd.com/read/28017340/feline-respiratory-extramedullary-plasmacytoma-with-lymph-node-metastasis-and-intrahistiocytic-amyloid
#17
S E Sykes, V Byfield, L Sullivan, S J Bender, P F Moore, M D Sánchez
A 14-year-old domestic longhaired cat presented with a 2-year history of nasal discharge and a recent onset of inappetence and submandibular lymphadenopathy. The cat was humanely destroyed after developing severe respiratory distress. Necropsy examination revealed thickened nasal turbinates and soft palate, and friable red-tan material within the frontal sinus, nasal cavity and nasopharynx. The lungs contained multifocal irregular friable tan nodules. Multiple lymph nodes were enlarged, friable and red-tan in colour...
December 22, 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28017262/correlation-between-acoustic-rhinometry-computed-rhinomanometry-and-cone-beam-computed-tomography-in-mouth-breathers-with-transverse-maxillary-deficiency
#18
Raquel Harumi Uejima Satto Sakai, Fernando Augusto Lima Marson, Emerson Taro Inoue Sakuma, José Dirceu Ribeiro, Eulália Sakano
INTRODUCTION: To provide clinical information and diagnosis in mouth breathers with transverse maxillary deficiency with posterior crossbite. Numerous exams can be performed; however, the correlation among these exams remains unclear. OBJECTIVE: To evaluate the correlation between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency. METHODS: A cross-sectional study was conducted in 30 mouth breathers with transverse maxillary deficiency (7-13 y...
November 25, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28003552/performance-of-the-new-turbine-mid-level-critical-care-ventilators
#19
Carlos Delgado, Jose E Romero, Jaume Puig, Ana Izquierdo, Carlos Ferrando, F Javier Belda, Marina Soro
BACKGROUND: During recent years, ventilators using turbines as flow-generating systems have become increasingly more relevant. This bench study was designed to compare triggering and pressurization of 7 turbine mid-level ICU ventilators. METHODS: We used a dual-chamber lung model to test 7 mid-level ICU ventilators in pressure support mode with levels of 10, 15, and 20 cm H2O with 2 PEEP levels of 5 cm H2O and the minimum level allowed by the ventilator. A ventilator was connected to the master chamber to simulate 2 different effort levels...
January 2017: Respiratory Care
https://www.readbyqxmd.com/read/28003522/patterns-of-migrating-soaring-migrants-indicate-attraction-to-marine-wind-farms
#20
Henrik Skov, Mark Desholm, Stefan Heinänen, Johnny A Kahlert, Bjarke Laubek, Niels Einar Jensen, Ramūnas Žydelis, Bo Præstegaard Jensen
Monitoring of bird migration at marine wind farms has a short history, and unsurprisingly most studies have focused on the potential for collisions. Risk for population impacts may exist to soaring migrants such as raptors with K-strategic life-history characteristics. Soaring migrants display strong dependence on thermals and updrafts and an affinity to land areas and islands during their migration, a behaviour that creates corridors where raptors move across narrow straits and sounds and are attracted to islands...
December 2016: Biology Letters
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