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https://www.readbyqxmd.com/read/28103861/the-saskatchewan-new-brunswick-healthy-start-d%C3%A3-part-sant%C3%A3-intervention-implementation-cost-estimates-of-a-physical-activity-and-healthy-eating-intervention-in-early-learning-centers
#1
Nazmi Sari, Nazeem Muhajarine, Amanda Froehlich Chow
BACKGROUND: Participation in daily physical activity and consuming a balanced diet high in fruits and vegetables and low in processed foods are behaviours associated with positive health outcomes during all stages of life. Previous literature suggests that the earlier these behaviours are established the greater the health benefits. As such, early learning settings have been shown to provide an effective avenue for exploring and influencing the physical activity and healthy eating behaviours of children before school entry...
January 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28081164/economic-evaluation-of-pcsk9-inhibitors-in-reducing-cardiovascular-risk-from-health-system-and-private-payer-perspectives
#2
Alejandro Arrieta, Timothy F Page, Emir Veledar, Khurram Nasir
The introduction of Proprotein covertase subtilisin/kexin type 9 (PCSK9) inhibitors has been heralded as a major advancement in reducing low-density lipoprotein cholesterol levels by nearly 50%. However, concerns have been raised on the added value to the health care system in terms of their costs and benefits. We assess the cost-effectiveness of PCSK9 inhibitors based on a decision-analytic model with existing clinical evidence. The model compares a lipid-lowering therapy based on statin plus PCSK9 inhibitor treatment with statin treatment only (standard therapy)...
2017: PloS One
https://www.readbyqxmd.com/read/28074382/engaging-hmong-adults-in-genomic%C3%A2-and%C3%A2-pharmacogenomic-research-toward-reducing-health-disparities-in-genomic-knowledge-using-a-community-based-participatory-research-approach
#3
Kathleen A Culhane-Pera, Robert J Straka, MaiKia Moua, Youssef Roman, Pachia Vue, Kang Xiaaj, May Xia Lo, Mai Lor
Advancing precision medicine relies in part on examining populations that may exhibit unique genetic variants that impact clinical outcomes. Failure to include diverse populations in genomic-based research represents a health disparity. We implemented a community-based participatory research (CBPR) process with the Hmong community in Minnesota, who were refugees from Laos, in order to assess the feasibility of conducting genomic and pharmacogenomic-based research for genetic variants that are relevant to the Hmong community...
January 10, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28048333/mo-a-209-01-aapm-journal-finances-facts-figures-and-fundamentals
#4
S Armato
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047682/mo-a-209-02-a-tale-of-two-journals-open-access-and-subscription-based-publications
#5
J Bourland
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047033/mo-a-209-03-a-look-ahead-stewarding-the-financial-future-of-aapm-journals
#6
M Svatos
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046257/mo-a-209-00-financial-perspectives-on-scientific-publishing
#7
Samuel Armato
: Scientific publishing is a major endeavor of the AAPM. Although publishing requires substantial resources, it has the potential to generate both reputation and revenue to further the missions of our society. The AAPM owns and publishes two journals: Medical Physics and the Journal of Applied Clinical Medical Physics (JACMP). Medical Physics, with the tagline "The international journal of medical physics research and practice," publishes research concerned with the application of physics and mathematics to the solution of problems in medicine and human biology, with an emphasis on theoretical and experimental approaches...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043097/costs-of-diarrhoea-and-acute-respiratory-infection-attributable-to-not-handwashing-the-cases-of-india-and-china
#8
Joy Townsend, Katie Greenland, Val Curtis
OBJECTIVE: To estimate the national costs relating to diarrhoea and acute respiratory infections from not handwashing with soap after contact with excreta and the costs and benefits of handwashing behaviour change programmes in India and China. METHODS: Data on the reduction in risk of diarrhoea and acute respiratory infection attributable to handwashing with soap were used, together with World Health Organization (WHO) estimates of disability-adjusted life years (DALYs) due to diarrhoea and acute respiratory infection, to estimate DALYs due to not handwashing in India and China...
January 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28034479/legitimation-dynamics-how-sroi-could-mobilize-resources-for-new-constituencies
#9
Kate Cooney
The following critical essay on the social return on investment (SROI) methodology is broken into two parts. In the first section, focusing on the categorization dynamics of the SROI, I review a set of methodological and ethical tensions surrounding the SROI, using examples from my own work and other published works using SROI. These tensions include the fact that the project requires standardization to achieve comparability while concurrently offering a flexibility in constructing a narrative of impact that is attractive to users...
December 19, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28033081/clinical-databases-and-registries-in-congenital-and-pediatric-cardiac-surgery-cardiology-critical-care-and-anesthesiology-worldwide
#10
David F Vener, Michael Gaies, Jeffrey P Jacobs, Sara K Pasquali
The growth in large-scale data management capabilities and the successful care of patients with congenital heart defects have coincidentally paralleled each other for the last three decades, and participation in multicenter congenital heart disease databases and registries is now a fundamental component of cardiac care. This manuscript attempts for the first time to consolidate in one location all of the relevant databases worldwide, including target populations, specialties, Web sites, and participation information...
January 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28032777/a-diversified-portfolio-model-of-adaptability
#11
Siddharth Chandra, Frederick T L Leong
A new model of adaptability, the diversified portfolio model (DPM) of adaptability, is introduced. In the 1950s, Markowitz developed the financial portfolio model by demonstrating that investors could optimize the ratio of risk and return on their portfolios through risk diversification. The DPM integrates attractive features of a variety of models of adaptability, including Linville's self-complexity model, the risk and resilience model, and Bandura's social cognitive theory. The DPM draws on the concept of portfolio diversification, positing that diversified investment in multiple life experiences, life roles, and relationships promotes positive adaptation to life's challenges...
December 2016: American Psychologist
https://www.readbyqxmd.com/read/28031076/assessment-of-lifetime-performance-of-small-ruminants-under-different-feeding-systems
#12
T A Amole, M Zijlstra, K Descheemaeker, A A Ayantunde, A J Duncan
Evaluation of lifetime productivity of individual animals in response to various interventions allows assessment of long-term investment opportunities for farmers. In order to gain a better understanding of promising feed interventions for improvement of small ruminant production in Southwestern Nigeria, a dynamic modelling approach was used to explore the effect of different feeding strategies on the lifetime productivity of West African Dwarf (WAD) goats. Modifications were made to the current version of Livestock Simulator developed for cattle production to simulate goat production systems particularly for WAD goats...
December 29, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28018024/returns-to-food-and-agricultural-r-d-investments-in-sub-saharan-africa-1975-2014
#13
Philip G Pardey, Robert S Andrade, Terrance M Hurley, Xudong Rao, Frikkie G Liebenberg
Research-enabled growth in agricultural productivity is pivotal to sub-Saharan Africa's overall economic growth prospects. Yet, investments in research and development (R&D) targeted to many national food and agricultural economies throughout Africa are fragile and faltering. To gain insight into what could be driving this trend, this article updates, summarizes and reassesses the published evidence on the returns to African agricultural R&D. Based on a compilation of 113 studies published between 1975 and 2014 spanning 25 countries, the reported internal rates of return (IRRs) to food and agricultural research conducted in or of direct consequence for sub-Saharan Africa averaged 42...
December 2016: Food Policy
https://www.readbyqxmd.com/read/28011094/using-cost-benefit-analysis-and-social-return-on-investment-to-evaluate-the-impact-of-social-enterprise-promises-implementation-and-limitations
#14
Joseph J Cordes
Since the early 2000's there has been growing interest in using the Social Return on Investment (SROI) as a measure for assessing the performance of social enterprises. By analogy with its business counterpart, the Return on Investment (ROI), the SROI is a metric that compares the monetized social costs of a program with the monetized social benefits of achieving an outcome (or set of outcomes). For example, calculating the SROI of a nonprofit half-way house for drug addicts might involve estimating the reduced social costs attributable to successful rehabilitation of addicts, and comparing this to the social costs of operating the half-way house...
November 21, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27994937/the-growing-need-for-microservices-in-bioinformatics
#15
Christopher L Williams, Jeffrey C Sica, Robert T Killen, Ulysses G J Balis
OBJECTIVE: Within the information technology (IT) industry, best practices and standards are constantly evolving and being refined. In contrast, computer technology utilized within the healthcare industry often evolves at a glacial pace, with reduced opportunities for justified innovation. Although the use of timely technology refreshes within an enterprise's overall technology stack can be costly, thoughtful adoption of select technologies with a demonstrated return on investment can be very effective in increasing productivity and at the same time, reducing the burden of maintenance often associated with older and legacy systems...
2016: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/27992772/the-role-of-imperfect-surrogate-endpoint-information-in-drug-approval-and-reimbursement-decisions
#16
Katalin Bognar, John A Romley, Jay P Bae, James Murray, Jacquelyn W Chou, Darius N Lakdawalla
Approval of new drugs is increasingly reliant on "surrogate endpoints," which correlate with but imperfectly predict clinical benefits. Proponents argue surrogate endpoints allow for faster approval, but critics charge they provide inadequate evidence. We develop an economic framework that addresses the value of improvement in the predictive power, or "quality," of surrogate endpoints, and clarifies how quality can influence decisions by regulators, payers, and manufacturers. For example, the framework shows how lower-quality surrogates lead to greater misalignment of incentives between payers and regulators, resulting in more drugs that are approved for use but not covered by payers...
December 11, 2016: Journal of Health Economics
https://www.readbyqxmd.com/read/27979379/social-return-on-investment-sroi-problems-solutions-%C3%A2-and-is-sroi-a-good-investment
#17
Brian T Yates, Mita Marra
The conclusion of this special issue on Social Return On Investment (SROI) begins with a summary of both advantages and problems of SROI, many of which were identified in preceding articles. We also offer potential solutions for some of these problems that can be derived from standard evaluation practices and that are becoming expected in SROIs that follow guidances from international SROI networks. A remaining concern about SROI is that we do not yet know if SROI itself adds sufficient benefit to programs to justify its cost...
December 8, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27977293/development-of-a-sleep-telementorship-program-for-rural-department-of-veterans-affairs-primary-care-providers-sleep-va-echo
#18
Elizabeth C Parsons, Elizabeth A Mattox, Lauren A Beste, David H Au, Bessie A Young, Michael F Chang, Brian N Palen
RATIONALE: Primary care providers (PCPs) frequently encounter sleep complaints, especially in regions with limited specialty care access. OBJECTIVES: The US Department of Veterans Affairs Extension for Community Healthcare Outcomes (VA-ECHO) program (based on Project ECHO) has successfully provided rural PCP education in subspecialty areas, including hepatitis C. We describe the feasibility of an ECHO program for sleep medicine. METHODS: ECHO creates a virtual learning community through video-teleconferencing, combining didactics with individualized clinical case review...
December 15, 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27971861/social-return-on-investment-in-psoriasis
#19
R Villoro, A Hidalgo, A González, M Jiménez, Y Ivanova, M Merino, S Alfonso-Zamora, G Carretero, A Ledesma, C Blanch, Expert Group On Sroi-Psoriasis
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27968827/operational-challenges-to-the-1-3-7-surveillance-strategy-for-malaria-elimination-in-china-a-qualitative-study
#20
Guang-Yu Lu, Yao-Bao Liu, Claudia Beiersmann, Yu Feng, Jun Cao, Olaf Müller
BACKGROUND: China aims to eliminate malaria by 2020. In 2012, China launched its 1-3-7 malaria surveillance strategy, which refers to case reporting within one day, case investigation within three days, and focus investigation and public health actions within seven days. The aim of this study was to identify operational challenges to the 1-3-7 surveillance strategy. METHODS: This qualitative study was conducted in northwestern (Gansu Province) and southeastern (Jiangsu Province) China...
October 2016: Lancet
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