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https://www.readbyqxmd.com/read/29211491/complications-and-care-related-to-pregnancy-labor-and-delivery-among-active-component-service-women-u-s-armed-forces-2012-2016
#1
Shauna Stahlman, Catherine T Witkop, Leslie L Clark, Stephen B Taubman
Diagnoses of "complications of pregnancy, childbirth, and the puerperium" include both morbid complications and indications for routine care of pregnant women. During 2012-2016, a total of 55,601 U.S. service members with live births (n=63,879) had 657,060 medical encounters with primary diagnoses of "pregnancy complications." The most frequent diagnoses were "other" specified conditions complicating pregnancy, childbirth, or the puerperium. Numbers of medical encounters with a primary (first-listed) diagnosis of any pregnancy-related complication or indication for care decreased marginally each year between 2012 (n=178,703) and 2016 (n=146,282)...
November 2017: MSMR
https://www.readbyqxmd.com/read/29207452/congenital-malformations-in-infants-of-mothers-undergoing-assisted-reproductive-technologies-a-systematic-review-and-meta-analysis-study
#2
Hayedeh Hoorsan, Parvin Mirmiran, Shahla Chaichian, Yousef Moradi, Roza Hoorsan, Fatemeh Jesmi
Objectives: This meta-analysis aimed to evaluate congenital malformations in infants conceived by assisted reproductive techniques (ART), compared with infants conceived spontaneously. Methods: In this study, available resources searched to find relevant articles included PubMed, ScienceDirect, Scopus, Google Scholar, Cochrane, ProQuest, Iranmedex, Magiran, and Scientific Information Database. After extracting the necessary information from evaluated articles, meta-analysis on the articles' data was performed using Stata version 11...
November 2017: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/29206066/magnesium-induces-preconditioning-of-the-neonatal-brain-via-profound-mitochondrial-protection
#3
Gabriella Koning, Anna-Lena Leverin, Syam Nair, Leslie Schwendimann, Joakim Ek, Ylva Carlsson, Pierre Gressens, Claire Thornton, Xiaoyang Wang, Carina Mallard, Henrik Hagberg
Magnesium sulphate (MgSO4) given to women in preterm labor reduces cerebral palsy in their offspring but the mechanism behind this protection is unclear, limiting its effective, safe clinical implementation. Previous studies suggest that MgSO4 is not neuroprotective if administered during or after the insult, so we hypothesised that MgSO4 induces preconditioning in the immature brain. Therefore, we administered MgSO4 at various time-points before/after unilateral hypoxia-ischemia (HI) in seven-day-old rats...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29205573/serum-relaxin-and-cervical-length-for-the-prediction-of-spontaneous-preterm-birth-in-second-trimester-symptomatic-women
#4
Athanasios Pantelis, Alexandros Sotiriadis, Kimon Chatzistamatiou, Georgios Pratilas, Konstantinos Dinas
OBJECTIVE: to investigate whether serum relaxin is associated with preterm birth in symptomatic women, either as a standalone test or in the context of a combined model. METHODS: This was a case-control study of women with singleton pregnancy, who presented between 24+0 and 26+6 weeks with threatened preterm labor and intact membranes. Cervical length, full blood count, C-reactive protein and maternal demographics were recorded at presentation. Blood samples were taken for relaxin and these parameters were compared between women who delivered <37 weeks (N=46) and women delivering at term (N=66)...
December 5, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29202976/perinatal-outcomes-after-natural-conception-versus-in%C3%A2-vitro-fertilization-ivf-in-gestational-surrogates-a-model-to-evaluate-ivf-treatment-versus-maternal-effects
#5
Irene Woo, Rita Hindoyan, Melanie Landay, Jacqueline Ho, Sue Ann Ingles, Lynda K McGinnis, Richard J Paulson, Karine Chung
OBJECTIVE: To study the perinatal outcomes between singleton live births achieved with the use of commissioned versus spontaneously conceived embryos carried by the same gestational surrogate. DESIGN: Retrospective cohort study. SETTING: Academic in vitro fertilization center. PATIENT(S): Gestational surrogate. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Pregnancy outcome, gestational age at birth, birth weight, perinatal complications...
December 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29202469/h3k27me3-dynamics-dictate-evolving-uterine-states-in-pregnancy-and-parturition
#6
Patrice Nancy, Johan Siewiera, Gabrielle Rizzuto, Elisa Tagliani, Ivan Osokine, Priyanka Manandhar, Igor Dolgalev, Caterina Clementi, Aristotelis Tsirigos, Adrian Erlebacher
Uncovering the causes of pregnancy complications such as preterm labor requires greater insight into how the uterus remains in a noncontractile state until term and then surmounts this state to enter labor. Here, we show that dynamic generation and erasure of the repressive histone modification tri-methyl histone H3 lysine 27 (H3K27me3) in decidual stromal cells dictate both elements of pregnancy success in mice. In early gestation, H3K27me3-induced transcriptional silencing of select gene targets ensured uterine quiescence by preventing the decidua from expressing parturition-inducing hormone receptors, manifesting type 1 immunity, and most unexpectedly, generating myofibroblasts and associated wound-healing responses...
November 27, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29201669/comparison-of-outcomes-of-ivf-cycles-between-transferred-frozen-thawed-embryos-and-fresh-embryos-by-a-2-year-survey
#7
Ensieh Shahrokh-Tehraninejad, Zeynab Vosoog, Fatemeh Farajzadeh-Vajari
Background: Infertility as one of most concerning topics in childbearing age mothers needs better managements with less complications and IVF can be assumed as an efficient method. This study aimed to compare pregnancy outcomes in fresh and frozen embryos transferred in IVF cycles. Methods: In a retrospective study, 11201 patients underwent IVF cycles from 21st March 2013 to 20th March 2014 and they were categorized into two groups according to age, previous tubal disease and surgery, tubal ligation, and previous ectopic pregnancy variables...
October 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/29198155/delayed-second-twin-delivery-benefits-and-risks
#8
Mohamed Farghali, Ibrahim Abdelazim, Khaled Abdelrazek
BACKGROUND: An increasing number of reports describe the delayed second twin delivery for days, or weeks with good results in the majority of the cases, and different survival rate between centers, without reported randomized controlled trials (RCTs). OBJECTIVES: This study was designed to evaluate the suggested management of the delayed second twin delivery in the Sabah Maternity Hospital regarding its outcome, possible risks, and benefits. PATIENTS AND METHODS: Forty-seven twin pregnancies with preterm labor of the first fetus between 20-30 weeks, and delayed delivery of the second twin were included in this study...
December 3, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29198051/doula-services-within-a-healthy-start-program-increasing-access-for-an-underserved-population
#9
Mary-Powel Thomas, Gabriela Ammann, Ellen Brazier, Philip Noyes, Aletha Maybank
PURPOSE: Women of color in the United States, particularly in high-poverty neighborhoods, experience high rates of poor birth outcomes, including cesarean section, preterm birth, low birthweight, and infant mortality. Doula care has been linked to improvements in many perinatal outcomes, but women of color and low-income women often face barriers in accessing doula support. DESCRIPTION: To address this issue, the New York City Department of Health and Mental Hygiene's Healthy Start Brooklyn introduced the By My Side Birth Support Program in 2010...
December 2, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29193454/amniotic-fluid-pentraxins-potential-early-markers-for-identifying-intra-amniotic-inflammatory-complications-in-preterm-pre-labor-rupture-of-membranes
#10
Ivana Musilova, Ctirad Andrys, Jan Krejsek, Marcela Drahosova, Barbora Zednikova, Lenka Pliskova, Helena Zemlickova, Bo Jacobsson, Marian Kacerovsky
In this study, pentraxin 3 (PTX3), C-reactive protein (CRP), and serum amyloid P component (SAP) concentrations in the amniotic fluid of women with preterm pre-labor rupture of membranes (PPROM) were evaluated based on evidence of microbial invasion of the amniotic cavity (MIAC), intra-amniotic inflammation (IAI), and microbial-associated IAI. A total of 149 women with PPROM were included in this study. Amniotic fluid samples were obtained by transabdominal amniocentesis. Amniotic fluid PTX3, SAP, and CRP concentrations were assessed using enzyme-linked immunosorbent assay...
November 28, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29191629/effects-of-thc-on-human-amniotic-epithelial-cell-proliferation-and-migration
#11
J L Yao, Q Z He, M Liu, X W Chang, J T Wu, T Duan, K Wang
BACKGROUND: The deleterious effects of cannabis consumption for fertility and pregnancy outcome are recognized for years. The main psychoactive molecule of cannabis, Δ(9)-tetrahydrocannabinol (THC) is able to cross the placenta barrier and cause alterations in fetal growth, low birth weight and preterm labor. However, the effects of THC on the human placenta amnion are still unknown. METHODS: The distributions of CB1R and CB2R in human amnion tissues were observed by immunohistochemistry (IHC)...
November 27, 2017: Toxicology
https://www.readbyqxmd.com/read/29191291/tocolysis-present-and-future-treatment-options
#12
REVIEW
Joshua D Younger, Elena Reitman, George Gallos
In the United States, the generally accepted indication for tocolytic therapy centers on suppression of preterm labor. This may be in the form of preventative therapy with progesterone in women with prior spontaneous preterm birth or as an acute intervention to suppress established uterine contractions associated with cervical change occurring at less than 37 weeks gestation. This article seeks to apply this perspective to tocolytic therapy. Here, we provide a review of current tocolytic options and what the last decade of discovery has revealed about the regulation of myometrial excitability and quiescence...
December 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/29180906/perceived-acceptability-of-progesterone-to-prevent-preterm-births-and-low-birth-weight-among-hiv-infected-and-hiv-uninfected-zambian-pregnant-women
#13
Jeffrey Man Hay Wong, Neha Kanga, Nupur Dogra, Mary Shilalukey Ngoma, Lena Serghides, Michael Silverman
Introduction: Intramuscular and vaginal progesterone are recommended for prevention of preterm labor (PTL) in women with risk factors. Studies are emerging to indicate that HIV-infected women on combination antiretroviral therapy (cART) are at risk of PTL and low birth weight (LBW), and may benefit from supplemental progesterone. This study aims to determine the perceived acceptability of various modes of progesterone supplementation to prevent PTL and LBW in HIV-infected and HIV-uninfected women...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29180840/candida-chorioamnionitis-leads-to-preterm-birth-and-adverse-fetal-neonatal-outcome
#14
REVIEW
Yohei Maki, Midori Fujisaki, Yuichiro Sato, Hiroshi Sameshima
Candida chorioamnionitis is rare but can lead to neonatal infection, high mortality, and neurodevelopmental impairment. We aimed to investigate maternal clinical features and perinatal outcomes and discuss future management strategies. We reviewed the medical records of women with Candida chorioamnionitis at our hospital over a 10-year period (n = 9) and previous published case reports and case series. The most prevalent Candida species was C. albicans (71.3% of the all cases). The most prevalent predisposing condition was preterm premature rupture of membranes (31/123, 25...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29179562/effects-of-support-interventions-in-women-hospitalized-with-preterm-labor
#15
Mei-Hua Kao, Pi-Feng Hsu, Sheng-Fang Tien, Chie-Pein Chen
This study was to examine the effects of support interventions on anxiety, depression, and quality of life in women hospitalized with preterm labor. A randomized, single-blind experimental design was used. Participants were recruited from maternity wards of one medical center in Taiwan. The control group ( n = 103) received routine nursing care, and intervention group ( n = 140) received interventional support during hospitalization. The Beck Anxiety Inventory, Edinburgh Postnatal Depression Scale, and Quality of Life Enjoyment and Satisfaction Questionnaire were used at admission and 2 weeks of hospitalization...
November 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/29168162/house-parties-an-innovative-model-for-outreach-and-community-based-health-education
#16
Timika Anderson-Reeves, Jacqueline Goodman, Brian Bragg, Chelsey Leruth
Purpose To connect low resource communities to innovative services that address gaps in health access and knowledge. Description We describe the house party model, as a community-based workshop approach to health education developed by the Westside Healthy Start program (WHS) in Chicago, Illinois. Key elements of the WHS house party model include use of community health workers as facilitators, collaboration with participants and community-based organizations, referrals to health care and social services, and engagement strategies such as interactive activities, personal stories, and discussion...
November 22, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29167041/efficacy-of-an-internet-based-cognitive-behavioral-stress-management-training-in-women-with-idiopathic-preterm-labor-a-randomized-controlled-intervention-study
#17
Corinne Urech, Sandra Scherer, Martina Emmenegger, Jens Gaab, Sibil Tschudin, Irène Hoesli, Thomas Berger, Judith Alder
OBJECTIVE: This randomized controlled trial aimed at evaluating the efficacy of an internet-based cognitive behavioral stress management program (IB-CBSM) for pregnant women with preterm labor (PTL) on birth outcome and stress-related psychological and biological parameters. METHODS: 93 pregnant women with PTL (gestational age 18-32) were assigned to either the IB-CBSM (n=50) or a control group (CG) based on distraction (n=43). Participants in both groups worked through six weekly modules...
December 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29166819/pregnancy-outcomes-among-women-with-asthma
#18
Haitham Baghlaf, Andrea R Spence, Nicholas Czuzoj-Shulman, Haim Arie Abenhaim
PURPOSE: The purpose of this study is to examine the association between maternal asthma and pregnancy, delivery and neonatal outcomes. MATERIALS AND METHODS: We carried out a retrospective cohort study using the Health Care Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) database from 2003 to 2011. Among women who delivered during this time period, we compared pregnancy, delivery, and neonatal outcomes in asthmatics versus non-asthmatics. Multivariate logistic regression was used to estimate adjusted odds ratios and 95% confidence intervals...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29162952/oral-health-status-and-fertility-treatment-including-ivf
#19
REVIEW
Sunali Sundeep Khanna, Prita A Dhaimade, Shalini Malhotra
Oral health is extremely important for the general wellbeing of the individual. From a number of research articles, it is established that there is a definitive connection between periodontal health and many systemic diseases, like type II diabetes, cardiovascular diseases and even preterm labor and low birth weight of babies. The significant rate of failure in the treatment of infertility and IVF (in vitro fertilization) even with multiple advancements in the last decade has made scientist take interest in newer parameters of health, an important one among them being periodontal health...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29157455/identification-of-preterm-birth-based-on-rqa-analysis-of-electrohysterograms
#20
Marta Borowska, Ewelina Brzozowska, Paweł Kuć, Edward Oczeretko, Romuald Mosdorf, Piotr Laudański
BACKGROUND AND OBJECTIVE: Common methods for data analysis are mainly based on linear concepts, but in recent years nonlinear dynamics methods have been introduced. It is a well-known fact that In typical biological systems lack of stationarity and rather sudden changes of state are the properties distinguishing them from each other. There is an urgent need to better understand the mechanical activity of the myometrium (its contractility) to find a solution for preterm delivery problem, the largest cause of neonatal deaths and morbidity...
January 2018: Computer Methods and Programs in Biomedicine
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