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Interstitial cystits

Donna J Carrico, Kenneth M Peters, Ananias C Diokno
INTRODUCTION: In the United States, more than 1 million women and men are affected with interstitial cystititis (IC), which is a clinical syndrome involving urinary urgency, frequency, and pelvic pain. A review of the literature revealed that there are no studies showing the effect of guided imagery in women with IC. The purpose of this clinical investigation was to explore the effect of guided imagery on pelvic pain and urinary symptoms in women with IC symptoms. METHODOLOGY: Thirty (30) women with diagnosed IC were randomized into 2 equal groups...
January 2008: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
G Hohlbrugger, C Riedl
The concept of non-bacterial cystitis (NBC) combines sterile urine and cystitic symptoms as well as inflammatory changes, in particular in the mucosa and submucosa of the bladder. It includes a multiplicity of vicious circles along the entire continence reflex. An understanding of NBC presupposes knowledge of the origin of the normal urinary urge and its successful control. Against the background of the steadily increasing incidence of interstitial cystitis (often irreversible end-stage NBC), it is suggested here that in the face of a failure of first-line therapeutics (anticholinergics, cyclic antidepressants or oestrogens), one must consider without delay the possible presence of NBC...
September 2000: Current Opinion in Urology
F Aldenborg, R Peeker, M Fall, A Olofsson, L Enerbäck
Mucosal mast cells (MCs) are normally found in the connective tissue stroma but are redistributed into the epithelium in conditions associated with immunoglobulin E responses, such as allergic inflammation and nematode infections, as well as in interstitial cystitis, a condition of unknown etiology. The potential role of epithelium-derived factors in this response prompted this inquiry into growth and differentiation signaling in normal tissue as well as in tissues from five different metaplastic conditions of the urothelium (cystitic cystica, cystitis glandularis, colonic metaplasia, squamous cell metaplasia, and nephrogenic metaplasia)...
July 1998: American Journal of Pathology
A Ipiéns Aznar
The authors discuss the indications and technique as well as the results in four patients successfully treated by means of hydraulic distension for a non-tumoural vesical pathology. H.V.D. is still a new method in spite of the long time which has elapsed since the first descriptions although it is simple with few complications if one follows a correct technique. Its main scope is in the treatment of interstitial cystites, unstable bladders and vesical hematurias following radiotherapy, cancer or cytostatics, apart from its use in vesical tumours in which further experience is required in order to establish correctly its real possibilities and limitations although the first indications are also highly positive...
September 1978: Archivos Españoles de Urología
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