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https://www.readbyqxmd.com/read/28214588/the-experiences-of-a-biochemist-in-the-evolving-world-of-g-protein-dependent-signaling
#1
REVIEW
Richard A Cerione
This review describes how a biochemist and basic researcher (i.e. myself) came to make a career in the area of receptor-coupled signal transduction and the roles cellular signaling activities play both in normal physiology and in disease. Much of what has been the best part of this research life is due to the time I spent with Bob Lefkowitz (1982-1985), during an extraordinary period in the emerging field of G-protein-coupled receptors. Among my laboratory colleagues were some truly outstanding scientists including Marc Caron, the late Jeffrey Stadel, Berta Strulovici, Jeff Benovic, Brian Kobilka, and Henrik Dohlman, as well as many more...
February 15, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28203636/i-want-to-media-multitask-and-i-want-to-do-it-now-individual-differences-in-media-multitasking-predict-delay-of-gratification-and-system-1-thinking
#2
Dan Schutten, Kirk A Stokes, Karen M Arnell
Media multitasking, the concurrent use of multiple media forms, has been shown to be related to greater self-reported impulsivity and less self-control. These measures are both hallmarks of the need for immediate gratification which has been associated with fast, intuitive 'system-1' decision making, as opposed to more deliberate and effortful 'system-2' decision making. In Study 1, we used the Cognitive Reflection Task (CRT) to examine whether individuals who engage heavily in media multitasking differ from those who are light media multitaskers in their degree of system-1 versus system-2 thinking...
2017: Cogn Res Princ Implic
https://www.readbyqxmd.com/read/28203246/generalization-of-context-specific-training-in-individuals-with-mild-cognitive-impairment-an-event-related-potential-study
#3
Sam C C Chan, Tommy L H Lam, Kenneth N K Fong, Marco Y C Pang, Chetwyn C H Chan
BACKGROUND: This study examined the neural processes associated with the generalization of the effect of context-specific (CS) training to noncontextual situations among individuals with mild cognitive impairment (MCI). METHODS: Fourteen and 16 participants with MCI were randomly allocated to a Chinese calligraphy writing (CW) training or a control group, respectively. The CW participants learned how to write Chinese strokes in a semicursive style to construct characters, tapping on working memory functions...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/28203113/the-influence-of-parenting-on-maladaptive-cognitive-schema-a-cross-sectional-research-on-a-group-of-adults
#4
Monica Pellerone, Calogero Iacolino, Giuseppe Mannino, Ivan Formica, Simona Maria Zabbara
BACKGROUND: The literature emphasizes the role of early interpersonal experiences in the development of cognitive vulnerability; in particular, interruptions in early family relationships, parental unavailability and dysfunctional parenting are potential evolutionary precursors to negative cognitive style and emotional disorders. MATERIALS AND METHODS: This study measured the relationship of retrospective ratings on parental bonding with cognitive patterns in a group of Italian adults...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28199892/a-prognostic-index-pi-as-a-moderator-of-outcomes-in-the-treatment-of-depression-a-proof-of-concept-combining-multiple-variables-to-inform-risk-stratified-stepped-care-models
#5
Lorenzo Lorenzo-Luaces, Robert J DeRubeis, Annemieke van Straten, Bea Tiemens
BACKGROUND: Prognostic indices (PIs) combining variables to predict future depression risk may help guide the selection of treatments that differ in intensity. We develop a PI and show its promise in guiding treatment decisions between treatment as usual (TAU), treatment starting with a low-intensity treatment (brief therapy (BT)), or treatment starting with a high-intensity treatment intervention (cognitive-behavioral therapy (CBT)). METHODS: We utilized data from depressed patients (N=622) who participated in a randomized comparison of TAU, BT, and CBT in which no statistically significant differences in the primary outcomes emerged between the three treatments...
February 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28198077/translation-strategies-contradiction-and-the-theory-of-social-representations-why-discussing-needles-may-improve-blood-donor-retention
#6
Gail Moloney, Jane Hayman, Marguerite Gamble, Geoff Smith, Rob Hall
Retaining blood donors is a cost-effective way of ensuring a safe blood supply, yet despite the plethora of research, only 5.1% of the eligible population in Australia donate blood and 40% of these do not make a second donation. We offer an alternative to traditional approaches by conceptualizing blood donation within social representations theory as socially derived symbolic knowledge with a specific focus on cognitive polyphasia and Guimelli's (1998) normative and functional dimensions. An online survey, completed by 703 residents from NSW Australia, comprised a blood donation word association task, Likert-style questions constructed from previous word association data and contextualized blood donation statements...
February 15, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28192675/sentinels-of-breach
#7
Andrew J Hampton, Valerie L Shalin
Objective This paper identifies general properties of language style in social media to help identify areas of need in disasters. Background In the search for metrics of need in social media data, much of the existing literature ignores processes of language usage. Psychological concepts, such as narrative breach, Gricean maxims, and lexical marking in cognition, may assist the recovery of disaster-relevant metrics from altered patterns of word prevalence. Method We analyzed several hundred thousand location-specific microblogs from Twitter for Hurricane Sandy, Oklahoma tornadoes, and the Boston Marathon bombing along with a fantasy football control corpus, examining the relative frequency of words in 36 antonym pairs...
February 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28190916/psychometric-validation-of-a-simplified-form-of-the-picts-for-low-reading-level-populations
#8
David J Disabato, Johanna B Folk, John Wilson, Sharen Barboza, Jordan Daylor, June Tangney
The Psychological Inventory of Criminal Thinking Styles (PICTS) is one of the most widely used measures of criminal thinking. Although the PICTS has adequate psychometric qualities with many general population inmates, the measurement confound of reading ability may decrease its construct validity in low-literacy inmates. To help resolve this confound, we present psychometric evaluation of a simplified version of the PICTS (PICTS-SV) in which item language was simplified but item content was preserved. We first conducted Lexile analyses to confirm the reading level of the PICTS-SV is significantly lower than the original PICTS (i...
September 2016: Journal of Psychopathology and Behavioral Assessment
https://www.readbyqxmd.com/read/28190541/predictors-of-adherence-to-follow-up-recommendations-after-an-abnormal-pap-smear-among-underserved-inner-city-women
#9
Suzanne M Miller, Erin K Tagai, Kuang-Yi Wen, Minsun Lee, Siu-Kuen Azor Hui, Deirdre Kurtz, John Scarpato, Enrique Hernandez
OBJECTIVES: This study aimed to identify cognitive-affective predictors of adherence to initial diagnostic colposcopy and 6-month follow-up recommendations among underserved women. METHODS: A secondary data analysis was completed of a randomized clinical trial assessing tailored telephone counseling for colposcopy adherence after an abnormal screening Pap smear among 210 underserved inner-city women. RESULTS: Adherence to initial diagnostic colposcopy was significantly associated with greater self-efficacy (OR=1...
January 31, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28184207/analysis-of-mental-workload-in-online-shopping-are-augmented-and-virtual-reality-consistent
#10
Xiaojun Zhao, Changxiu Shi, Xuqun You, Chenming Zong
A market research company (Nielsen) reported that consumers in the Asia-Pacific region have become the most active group in online shopping. Focusing on augmented reality (AR), which is one of three major techniques used to change the method of shopping in the future, this study used a mixed design to discuss the influences of the method of online shopping, user gender, cognitive style, product value, and sensory channel on mental workload in virtual reality (VR) and AR situations. The results showed that males' mental workloads were significantly higher than females'...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28183085/reviving-research-on-medication-attitudes-for-improving-pharmacotherapy-focusing-on-adherence
#11
Carlos De Las Cuevas, Jose de Leon
There is little current interest in research into patients' attitudes toward medications. In the 1960s, psychiatric researchers including Uhlenhuth, Rickels and Covi focused on this area, but this research topic needs to be revived in the 21st century. The Health Belief Model may hold potential for doing this. This model was initially developed by 2 health psychologists, Rosenstock and Becker, to explain why patients did not follow medical interventions. The application of this model to study medication adherence in psychiatric outpatients has provided multiple findings including the conclusions that adherence is associated with: (1) the balance between internal and external health control beliefs, (2) psychological reactance, (3) patients' attitudes toward prescribed drug treatment in general and (4) the balance between the necessity of taking medications versus the concerns derived from adverse drug reactions (ADRs)...
February 10, 2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/28168764/evaluation-of-a-dietary-screener-the-mediterranean-eating-pattern-for-americans-tool
#12
L A Cerwinske, H E Rasmussen, S Lipson, A S Volgman, C C Tangney
BACKGROUND: Evidence exists for an association between accordance with a Mediterranean diet pattern and slower rates of cognitive decline. However, an 'Americanised' version of the Mediterranean diet screener is needed to assess accordance in the USA. Thus, the Mediterranean Eating Pattern for Americans (MEPA) tool was developed to assess accordance with a Mediterranean-like food pattern when time is limited. The present study aimed to determine whether the MEPA screener captured the key elements of the Mediterranean diet compared to the more comprehensive food frequency questionnaire (FFQ)...
February 7, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28167331/turning-lemonade-into-lemons-dampening-appraisals-reduce-positive-affect-and-increase-negative-affect-during-positive-activity-scheduling
#13
Leigh-Anne Burr, Mahmood Javiad, Grace Jell, Aliza Werner-Seidler, Barnaby D Dunn
The way individuals appraise positive emotions may modulate affective experience during positive activity scheduling. Individuals may either engage in dampening appraisals (e.g., think "this is too good to last") or amplifying appraisals (e.g., think "I deserve this"). A cross-over randomized design was used to examine the consequences of these appraisal styles. Participants (N = 43) rated positive affect (PA) and negative affect (NA) during four daily walks in pleasant locations, whilst following dampening, emotion-focus amplifying (focusing on how good one feels), self-focus amplifying (focusing on positive self qualities), or control instructions...
January 24, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28166081/the-art-of-pharmacotherapy-reflections-on-pharmacophobia
#14
Jose de Leon, Carlos De Las Cuevas
PURPOSE/BACKGROUND: This commentary deals with the neglected issue of the art of psychopharmacology by recounting the authors' journeys. METHODS/PROCEDURES: First, a model of medical science situated within the history of medicine is described including (1) a limitation of the mathematical model of science, (2) the distinction between mechanistic science and mathematical science, (3) how this distinction is applied to medicine, and (4) how this distinction is applied to explain pharmacology to psychiatrists...
February 3, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28164772/clinical-and-environmental-correlates-of-serum-bdnf-a-descriptive-study-with-plausible-implications-for-ad-research
#15
Galit Weinstein, Sarah R Preis, Alexa S Beiser, Bernhard Kaess, Tai C Chen, Claudia Satizabal, Faisal Rahman, Emelia J Benjamin, Vasan S Ramachandran, Sudha Seshadri
BACKGROUND: Brain derived neurotrophic factor (BDNF) may play a central role in the pathogenesis of Alzheimer's disease (AD) through neurotrophic effects on basal cholinergic neurons. Reduced serum levels of BDND are observed among AD patients and may predict AD risk. Nevertheless, knowledge about factors associated with its levels in blood is lacking. OBJECTIVE: To identify clinical and demographic correlated of serum BDNF levels . METHODS: BDNF was measured from serum collected between 1992-1996 and 1998-2001 in participants from the Original and Offspring cohorts of the Framingham Study, respectively...
February 2, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28163372/more-evidence-for-three-types-of-cognitive-style-validating-the-object-spatial-imagery-and-verbal-questionnaire-using-eye-tracking-when-learning-with-texts-and-pictures
#16
Tim N Höffler, Marta Koć-Januchta, Detlev Leutner
There is some indication that people differ regarding their visual and verbal cognitive style. The Object-Spatial Imagery and Verbal Questionnaire (OSIVQ) assumes a three-dimensional cognitive style model, which distinguishes between object imagery, spatial imagery and verbal dimensions. Using eye tracking as a means to observe actual gaze behaviours when learning with text-picture combinations, the current study aims to validate this three-dimensional assumption by linking the OSIVQ to learning behaviour. The results largely confirm the model in that they show the expected correlations between results on the OSIVQ, visuo-spatial ability and learning behaviour...
January 2017: Applied Cognitive Psychology
https://www.readbyqxmd.com/read/28160683/attachment-dysfunctional-attitudes-self-esteem-and-association-to-depressive-symptoms-in-patients-with-mood-disorders
#17
Kristina Fuhr, Ivanina Reitenbach, Jan Kraemer, Martin Hautzinger, Thomas D Meyer
BACKGROUND: Cognitive factors might be the link between early attachment experiences and later depression. Similar cognitive vulnerability factors are discussed as relevant for both unipolar and bipolar disorders. The goals of the study were to test if there are any differences concerning attachment style and cognitive factors between remitted unipolar and bipolar patients compared to controls, and to test if the association between attachment style and depressive symptoms is mediated by cognitive factors...
January 21, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28160626/improving-measurement-of-attributional-style-in-schizophrenia-a-psychometric-evaluation-of-the-ambiguous-intentions-hostility-questionnaire-aihq
#18
Benjamin Buck, Colin Iwanski, Kristin M Healey, Michael F Green, William P Horan, Robert S Kern, Junghee Lee, Stephen R Marder, Steve P Reise, David L Penn
While attributional style is regarded as a core domain of social cognition, questions persist about the psychometric characteristics of measures used to assess it. One widely used assessment of attributional style is the Ambiguous Intentions Hostility Questionnaire (AIHQ). Two limitations of the AIHQ include (1) a possible restricted range resulting from too few and too homogenous item scenarios, and (2) use of rater scores that are cumbersome and time-consuming to score and have unknown incremental validity...
January 9, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28159059/the-association-between-anorexia-of-aging-and-physical-frailty-results-from-the-national-center-for-geriatrics-and-gerontology-s-study-of-geriatric-syndromes
#19
Kota Tsutsumimoto, Takehiko Doi, Hyuma Makizako, Ryo Hotta, Sho Nakakubo, Keitaro Makino, Takao Suzuki, Hiroyuki Shimada
OBJECTIVES: The present study examined the association between anorexia of aging and physical frailty among older people. STUDY DESIGN: An observational, cross-sectional cohort design was used with a sample of 4417 elderly Japanese citizens living in a community setting. MAIN OUTCOME MEASURES: Frailty was operationalized as the following frailty components: slowness, weakness, exhaustion, low level of physical activity, and weight loss. Participants were grouped as non-frail, pre-frail, and frail, and categorized as anorexic or not using questionnaire cutoff scores...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28150989/dialectical-thinking-and-fairness-based-perspectives-of-affirmative-action
#20
Ivona Hideg, D Lance Ferris
Affirmative action (AA) policies are among the most effective means for enhancing diversity and equality in the workplace, yet are also often viewed with scorn by the wider public. Fairness-based explanations for this scorn suggest AA policies provide preferential treatment to minorities, violating procedural fairness principles of consistent treatment. In other words, to promote equality in the workplace, effective AA policies promote inequality when selecting employees, and the broader public perceives this to be procedurally unfair...
February 2, 2017: Journal of Applied Psychology
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