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Validation cost effectiveness simulation

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https://www.readbyqxmd.com/read/28924572/stereovision-based-integrated-system-for-point-cloud-reconstruction-and-simulated-brain-shift-validation
#1
Xiaochen Yang, Logan W Clements, Ma Luo, Saramati Narasimhan, Reid C Thompson, Benoit M Dawant, Michael I Miga
Intraoperative soft tissue deformation, referred to as brain shift, compromises the application of current image-guided surgery navigation systems in neurosurgery. A computational model driven by sparse data has been proposed as a cost-effective method to compensate for cortical surface and volumetric displacements. We present a mock environment developed to acquire stereoimages from a tracked operating microscope and to reconstruct three-dimensional point clouds from these images. A reconstruction error of 1 mm is estimated by using a phantom with a known geometry and independently measured deformation extent...
July 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28914940/asymmetric-dual-loop-feedback-to-suppress-spurious-tones-and-reduce-timing-jitter-in-self-mode-locked-quantum-dash-lasers-emitting-at-1-55%C3%A2-%C3%A2-%C3%AE-m
#2
Haroon Asghar, John G McInerney
We demonstrate an asymmetric dual-loop feedback method to suppress external cavity side-modes induced in self-mode-locked quantum-dash lasers with conventional single- and dual-loop feedback. In this Letter, we report optimal suppression of spurious tones by optimizing the delay in the second loop. We observed that asymmetric dual-loop feedback, with large (∼8×) disparity in loop lengths, gives significant suppression in external-cavity side-modes and produces flat radio frequency (RF) spectra close to the main peak with a low timing jitter, compared to single-loop feedback...
September 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28910743/is-scena-a-good-approach-for-side-stream-integrated-treatment-from-an-environmental-and-economic-point-of-view
#3
Stefano Longo, Nicola Frison, Daniele Renzi, Francesco Fatone, Almudena Hospido
The environmental and economic benefits and burdens of including the first Short Cut Enhanced Nutrient Abatement (SCENA) into a real municipal wastewater treatment plant were evaluated using life cycle assessment (LCA) and life cycle cost (LCC). The implications of accomplishing nitrogen (N) removal and phosphorus (P) recovery via nitrite in the side stream were assessed taking into account the actual effluent quality improvement, the changes in the electricity and chemical consumption, N2O, CO2 and CH4 emissions and the effects of land application of biosolids, among others...
September 6, 2017: Water Research
https://www.readbyqxmd.com/read/28892680/removal-and-recovery-of-acetic-acid-and-two-furans-during-sugar-purification-of-simulated-phenols-free-biomass-hydrolysates
#4
Sang Cheol Lee
A cost-effective five-step sugar purification process involving simultaneous removal and recovery of fermentation inhibitors from biomass hydrolysates was first proposed here. Only the three separation steps (PB, PC and PD) in the process were investigated here. Furfural was selectively removed up to 98.4% from a simulated five-component hydrolysate in a cross-current three-stage extraction system with n-hexane. Most of acetic acid in a simulated four-component hydrolysate was selectively removed by emulsion liquid membrane, and it could be concentrated in the stripping solution up to 4...
September 8, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28883717/assessing-balance-through-the-use-of-a-low-cost-head-mounted-display-in-older-adults-a-pilot-study
#5
Santiago J Saldana, Anthony P Marsh, W Jack Rejeski, Jack K Haberl, Peggy Wu, Scott Rosenthal, Edward H Ip
INTRODUCTION: As the population ages, the prevention of falls is an increasingly important public health problem. Balance assessment forms an important component of fall-prevention programs for older adults. The recent development of cost-effective and highly responsive virtual reality (VR) systems means new methods of balance assessment are feasible in a clinical setting. This proof-of-concept study made use of the submillimeter tracking built into modern VR head-mounted displays (VRHMDs) to assess balance through the use of visual-vestibular conflict...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28880366/determining-the-inventory-impact-of-extended-shelf-life-platelets-with-a-network-simulation-model
#6
John T Blake
BACKGROUND: The regulatory shelf life for platelets (PLTs) in many jurisdictions is 5 days. PLT shelf life can be extended to 7 days with an enhanced bacterial detection algorithm. Enhanced testing, however, comes at a cost, which may be offset by reductions in wastage due to longer shelf life. This article describes a method for estimating systemwide reductions in PLT outdates after PLT shelf life is extended. STUDY DESIGN AND METHODS: A simulation was used to evaluate the impact of an extended PLT shelf life within a national blood network...
September 6, 2017: Transfusion
https://www.readbyqxmd.com/read/28876611/construction-and-validation-of-low-cost-laparoscopic-simulator-using-android-smartphone-and-pop-cast-and-a-laptop
#7
A Vyas, G Goel
Minimal invasive surgery training requires a lot of practice and for this purpose innovative tools are needed to develop methods for practice and training skills outside the operating room. Commercially available devices are readily available but cost effectiveness and availability are major limiting factors in resource limited setting. We present an innovative and cost effective laparoscopic simulator which can be easily manufactured and used for practice of laparoscopic surgery. Using a free android application, such as IP webcam we can relay video to laptop without the use of any cables and uniquely we use the flash of a camera as the light source and a selfie stick for movement of the camera...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28872629/an-adaptive-low-cost-ins-gnss-tightly-coupled-integration-architecture-based-on-redundant-measurement-noise-covariance-estimation
#8
Zheng Li, Hai Zhang, Qifan Zhou, Huan Che
The main objective of the introduced study is to design an adaptive Inertial Navigation System/Global Navigation Satellite System (INS/GNSS) tightly-coupled integration system that can provide more reliable navigation solutions by making full use of an adaptive Kalman filter (AKF) and satellite selection algorithm. To achieve this goal, we develop a novel redundant measurement noise covariance estimation (RMNCE) theorem, which adaptively estimates measurement noise properties by analyzing the difference sequences of system measurements...
September 5, 2017: Sensors
https://www.readbyqxmd.com/read/28865242/novel-graphene-based-biosensor-for-early-detection-of-zika-virus-infection
#9
Savannah Afsahi, Mitchell B Lerner, Jason M Goldstein, Joo Lee, Xiaoling Tang, Dennis A Bagarozzi, Deng Pan, Lauren Locascio, Amy Walker, Francie Barron, Brett R Goldsmith
We have developed a cost-effective and portable graphene-enabled biosensor to detect Zika virus with a highly specific immobilized monoclonal antibody. Field Effect Biosensing (FEB) with monoclonal antibodies covalently linked to graphene enables real-time, quantitative detection of native Zika viral (ZIKV) antigens. The percent change in capacitance in response to doses of antigen (ZIKV NS1) coincides with levels of clinical significance with detection of antigen in buffer at concentrations as low as 450pM...
August 24, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28851678/automating-construction-of-machine-learning-models-with-clinical-big-data-proposal-rationale-and-methods
#10
Gang Luo, Bryan L Stone, Michael D Johnson, Peter Tarczy-Hornoch, Adam B Wilcox, Sean D Mooney, Xiaoming Sheng, Peter J Haug, Flory L Nkoy
BACKGROUND: To improve health outcomes and cut health care costs, we often need to conduct prediction/classification using large clinical datasets (aka, clinical big data), for example, to identify high-risk patients for preventive interventions. Machine learning has been proposed as a key technology for doing this. Machine learning has won most data science competitions and could support many clinical activities, yet only 15% of hospitals use it for even limited purposes. Despite familiarity with data, health care researchers often lack machine learning expertise to directly use clinical big data, creating a hurdle in realizing value from their data...
August 29, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28818990/clinical-use-and-utility-of-amyloid-imaging
#11
Henryk Barthel, Osama Sabri
Currently, three amyloid PET tracers are approved and commercially available for clinical use. They allow for the accurate in vivo detection of amyloid plaques, one hallmark of Alzheimer's disease (AD). Here, we review the current knowledge on the clinical use and utility of amyloid imaging. Appropriate use criteria for the clinical application of amyloid imaging are established, and most currently available data point to their validity. Visual amyloid image analysis is highly standardized. Disclosure of amyloid imaging results is desired by many cognitively impaired subjects, and seems to be safe once appropriate education is delivered to the disclosing clinicians...
August 17, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28773821/transverse-crack-detection-in-3d-angle-interlock-glass-fibre-composites-using-acoustic-emission
#12
Matthieu Gresil, Mohamed Nasr Saleh, Constantinos Soutis
In addition to manufacturing cost and production rates, damage resistance has become a major issue for the composites industry. Three-dimensional (3D) woven composites have superior through-thickness properties compared to two-dimensional (2D) laminates, for example, improved impact damage resistance, high interlaminar fracture toughness and reduced notch sensitivity. The performance of 3D woven preforms is dependent on the fabric architecture, which is determined by the binding pattern. For this study, angle interlock (AI) structures with through-thickness binding were manufactured...
August 16, 2016: Materials
https://www.readbyqxmd.com/read/28772879/on-line-multi-damage-scanning-spatial-wavenumber-filter-based-imaging-method-for-aircraft-composite-structure
#13
Yuanqiang Ren, Lei Qiu, Shenfang Yuan, Qiao Bao
Structural health monitoring (SHM) of aircraft composite structure is helpful to increase reliability and reduce maintenance costs. Due to the great effectiveness in distinguishing particular guided wave modes and identifying the propagation direction, the spatial-wavenumber filter technique has emerged as an interesting SHM topic. In this paper, a new scanning spatial-wavenumber filter (SSWF) based imaging method for multiple damages is proposed to conduct on-line monitoring of aircraft composite structures...
May 11, 2017: Materials
https://www.readbyqxmd.com/read/28763654/evaluating-the-risk-of-phosphorus-loss-with-a-distributed-watershed-model-featuring-zero-order-mobilization-and-first-order-delivery
#14
Sisi Li, Liang Zhang, Hongbin Liu, Hugo A Loáiciga, Limei Zhai, Yanhua Zhuang, Qiuliang Lei, Wanli Hu, Wenchao Li, Qi Feng, Yun Du
Many semi-distributed models that simulate pollutants' losses from watersheds do not handle well detailed spatially distributed and temporal data with which to identify accurate and cost-effective strategies for controlling pollutants issuing from non-point sources. Such models commonly overlook the flow pathways of pollutants across the landscape. This work aims at closing such knowledge gap by developing a Spatially and Temporally Distributed Empirical model for Phosphorus Management (STEM-P) that simulates the daily phosphorus loss from source areas to receiving waters on a spatially-distributed grid-cell basis...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28746390/homogenized-modeling-methodology-for-18650-lithium-ion-battery-module-under-large-deformation
#15
Liang Tang, Jinjie Zhang, Pengle Cheng
Effective lithium-ion battery module modeling has become a bottleneck for full-size electric vehicle crash safety numerical simulation. Modeling every single cell in detail would be costly. However, computational accuracy could be lost if the module is modeled by using a simple bulk material or rigid body. To solve this critical engineering problem, a general method to establish a computational homogenized model for the cylindrical battery module is proposed. A single battery cell model is developed and validated through radial compression and bending experiments...
2017: PloS One
https://www.readbyqxmd.com/read/28745934/spinal-cord-injury-clinical-registries-improving-care-across-the-sci-care-continuum-by-identifying-knowledge-gaps
#16
Marcel F Dvorak, Christiana L Cheng, Nader Fallah, Argelio Santos, Derek Atkins, Suzanne Humphreys, Carly S Rivers, Barry A B White, Chester Ho, Henry Ahn, Brian K Kwon, Sean Christie, Vanessa K Noonan
Timely access and ongoing delivery of care and therapeutic interventions is needed to maximize recovery and function after traumatic spinal cord injury (tSCI). To ensure these decisions are evidence-based, access to consistent, reliable, and valid sources of clinical data is required. The Access to Care and Timing Model used data from the Rick Hansen SCI Registry (RHSCIR) to generate a simulation of healthcare delivery for persons after tSCI and to test scenarios aimed at improving outcomes and reducing the economic burden of SCI...
July 26, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28738137/public-health-and-economic-consequences-of-vaccine-hesitancy-for-measles-in-the-united-states
#17
Nathan C Lo, Peter J Hotez
Importance: Routine childhood vaccination is declining in some regions of the United States due to vaccine hesitancy, which risks the resurgence of many infectious diseases with public health and economic consequences. There are ongoing policy debates on the state and national level, including legislation around nonmedical (personal-belief) exemptions for childhood vaccination and possibly a special government commission on vaccine safety, which may affect vaccine coverage. Objective: To estimate the number of measles cases in US children and the associated economic costs under scenarios of different levels of vaccine hesitancy, using the case example of measles, mumps, and rubella (MMR) vaccination and measles...
September 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28720354/training-modalities-in-robot-assisted-urologic-surgery-a-systematic-review
#18
REVIEW
Catherine Elizabeth Lovegrove, Oussama Elhage, M Shamim Khan, Giacomo Novara, Alex Mottrie, Prokar Dasgupta, Kamran Ahmed
CONTEXT: Novel surgical techniques demand that surgical training adapts to the need for technical and nontechnical skills. OBJECTIVE: To identify training methods available for robot-assisted surgical (RAS) training in urology, evaluate their effectiveness in terms of validation, educational impact, acceptability, and cost effectiveness, and assess their effect on learning curves (LCs). EVIDENCE ACQUISITION: A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines searched Ovid Medline, Embase, PsycINFO, and the Cochrane Library...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28676200/cigar-box-arthroscopy-a-randomized-controlled-trial-validates-nonanatomic-simulation-training-of-novice-arthroscopy-skills
#19
Rory P Sandberg, Nathan C Sherman, L Daniel Latt, Jolene C Hardy
PURPOSE: The goal of this study was to validate the cigar box arthroscopy trainer (CBAT) as a training tool and then compare its effectiveness to didactic training and to another previously validated low-fidelity but anatomic model, the anatomic knee arthroscopy trainer (AKAT). METHODS: A nonanatomic knee arthroscopy training module was developed at our institution. Twenty-four medical students with no prior arthroscopic or laparoscopic experience were enrolled as subjects...
July 1, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28673826/the-five-year-cost-effectiveness-of-two-level-anterior-cervical-discectomy-and-fusion-or-cervical-disc-replacement-a-markov-analysis
#20
Samuel C Overley, Steven J McAnany, Robert L Brochin, Jun S Kim, Robert K Merrill, Sheeraz A Qureshi
BACKGROUND CONTEXT: Anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (CDR) are both acceptable surgical options for the treatment of cervical myelopathy and/or radiculopathy. To date, there are limited economic analyses assessing the relative cost-effectiveness of two-level ACDF versus CDR. PURPOSE: The purpose of this study was to determine the five-year cost-effectiveness of two-level ACDF versus CDR. STUDY DESIGN: Secondary analysis of prospectively collected data...
June 30, 2017: Spine Journal: Official Journal of the North American Spine Society
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