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https://www.readbyqxmd.com/read/28646401/a-standardized-set-of-3-d-objects-for-virtual-reality-research-and-applications
#1
David Peeters
The use of immersive virtual reality as a research tool is rapidly increasing in numerous scientific disciplines. By combining ecological validity with strict experimental control, immersive virtual reality provides the potential to develop and test scientific theories in rich environments that closely resemble everyday settings. This article introduces the first standardized database of colored three-dimensional (3-D) objects that can be used in virtual reality and augmented reality research and applications...
June 23, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28638807/translational-rodent-models-for-research-on-parasitic-protozoa-a-review-of-confounders-and-possibilities
#2
REVIEW
Totta Ehret, Francesca Torelli, Christian Klotz, Amy B Pedersen, Frank Seeber
Rodents, in particular Mus musculus, have a long and invaluable history as models for human diseases in biomedical research, although their translational value has been challenged in a number of cases. We provide some examples in which rodents have been suboptimal as models for human biology and discuss confounders which influence experiments and may explain some of the misleading results. Infections of rodents with protozoan parasites are no exception in requiring close consideration upon model choice. We focus on the significant differences between inbred, outbred and wild animals, and the importance of factors such as microbiota, which are gaining attention as crucial variables in infection experiments...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28632188/smartphone-based-food-diagnostic-technologies-a-review
#3
REVIEW
Giovanni Rateni, Paolo Dario, Filippo Cavallo
A new generation of mobile sensing approaches offers significant advantages over traditional platforms in terms of test speed, control, low cost, ease-of-operation, and data management, and requires minimal equipment and user involvement. The marriage of novel sensing technologies with cellphones enables the development of powerful lab-on-smartphone platforms for many important applications including medical diagnosis, environmental monitoring, and food safety analysis. This paper reviews the recent advancements and developments in the field of smartphone-based food diagnostic technologies, with an emphasis on custom modules to enhance smartphone sensing capabilities...
June 20, 2017: Sensors
https://www.readbyqxmd.com/read/28617586/research-progress-towards-the-practical-applications-of-lithium-sulfur-li-s-batteries
#4
Joshua Lochala, Dianying Liu, Bingbin Wu, Cynthia Robinson, Jie Xiao
The renaissance of Li-S battery technology is witnessed by the intensive R&D efforts in recent years. Although the theoretical capacity and energy of a Li-S battery is theoretically very high, the projected usable energy is expected to be no more than twice that of state-of-art Li-ion batteries, or 500 Wh/kg. The recent "sulfur fever" has certainly gathered new knowledge on sulfur chemistry and electrochemistry, electrolytes, lithium metal and their interactions in this "new" system; however, a real advance towards a practical Li-S battery is still missing...
June 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28612085/moving-from-millifluidic-to-truly-microfluidic-sub-100-%C3%AE-m-cross-section-3d-printed-devices
#5
Michael J Beauchamp, Gregory P Nordin, Adam T Woolley
Three-dimensional (3D) printing has generated considerable excitement in recent years regarding the extensive possibilities of this enabling technology. One area in which 3D printing has potential, not only for positive impact but also for substantial improvement, is microfluidics. To date many researchers have used 3D printers to make fluidic channels directed at point-of-care or lab-on-a-chip applications. Here, we look critically at the cross-sectional sizes of these 3D printed fluidic structures, classifying them as millifluidic (larger than 1 mm), sub-millifluidic (0...
July 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28600024/efficacy-of-cilostazol-for-below-the-knee-artery-disease-after-balloon-angioplasty-in-patients-with-severe-limb-ischemia-cabbage-trial
#6
Yoshimitsu Soga, Mitsuyoshi Takahara, Osamu Iida, Yasutaka Yamauchi, Keisuke Hirano, Masashi Fukunaga, Kan Zen, Kenji Suzuki, Yoshiaki Shintani, Yusuke Miyashita, Taketsugu Tsuchiya, Terutoshi Yamaoka, Kenji Ando
BACKGROUND: Optimal medical therapy after endovascular therapy in patients with critical limb ischemia (CLI) remains unclear. Therefore, we investigated whether cilostazol reduce restenosis after balloon angioplasty for infrapopliteal lesions in CLI patietns. METHODS: This study was performed as a multicenter prospective randomized open-label blinded-endpoint study with independent angiographic core lab adjudication. Sixty patients were eligible and 53 patients were enrolled and allocated...
June 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28598725/a-critical-review-of-the-postulated-role-of-the-non-essential-amino-acid-%C3%AE-n-methylamino-l-alanine-in-neurodegenerative-disease-in-humans
#7
N Chernoff, D J Hill, D L Diggs, B D Faison, B M Francis, J R Lang, M M Larue, T-T Le, K A Loftin, J N Lugo, J E Schmid, W M Winnik
The compound BMAA (β-N-methylamino-L-alanine) has been postulated to play a significant role in four serious neurological human diseases: Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) found on Guam, and ALS, Parkinsonism, and dementia that occur globally. ALS/PDC with symptoms of all three diseases first came to the attention of the scientific community during and after World War II. It was initially associated with cycad flour used for food because BMAA is a product of symbiotic cycad root-dwelling cyanobacteria...
June 9, 2017: Journal of Toxicology and Environmental Health. Part B, Critical Reviews
https://www.readbyqxmd.com/read/28596319/data-check-critics-challenge-nih-finding-that-bigger-labs-aren-t-necessarily-better
#8
Jocelyn Kaiser
No abstract text is available yet for this article.
June 9, 2017: Science
https://www.readbyqxmd.com/read/28595555/microdialysis-assessed-adipose-tissue-metabolism-in-critically-ill-patients
#9
Ioannis Ilias, Nikitas Nikitas, Maria Theodorakopoulou, Ioanna Dimopoulou
BACKGROUND: Microdialysis is a minimally invasive technique that allows direct in situ and in vivo sampling, studies and manipulations of the interstitial/extracellular fluid/space. It has been shown to be of use mainly in acute brain injury/neurocritical care. METHODS: Microdialysis has been used to study obesity, diabetes mellitus, inflammation and pharmacokinetics at the adipose tissue level. In critically ill patients (and particularly in those with sepsis or septic shock), within days to weeks, adipose tissue shows profound alterations; under such conditions the implementation of microdialysis can provide researchers with interesting findings...
June 8, 2017: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
https://www.readbyqxmd.com/read/28594204/taking-forensic-mental-health-assessment-out-of-the-lab-and-into-the-real-world-introduction-to-the-special-issue-on-the-field-utility-of-forensic-assessment-instruments-and-procedures
#10
John F Edens, Marcus T Boccaccini
The last several decades have seen a major upswing in the development and use of psychological assessment instruments in forensic and correctional settings. At the same time, admissibility standards increasingly have stressed the importance of the reliability and validity of evidence in legal proceedings. Recent research has, however, raised serious concerns about (a) the reliability of forensic science evidence in general, (b) the replicability of psychological research findings in general and in field settings especially, and (c) the interrater reliability and predictive validity of forensic psychological assessment evidence in particular...
June 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28594067/feeling-the-pulse-of-chemistry-already-in-practical-laboratory-courses
#11
EDITORIAL
Roland A Fischer
"… The lessons that students can draw from a lab course are unique throughout the entire study of chemistry. Equally important and valuable is the authentic lab experience and the constant repetition of the link between acquiring knowledge, thorough observations, logical thinking, self-critical tenacity, and capacity for success throughout the experiments. The ultimate gain is satisfaction ..." Read more in the Editorial by Roland A. Fischer.
June 26, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28575708/education-of-student-nurses-a-systematic-literature-review
#12
REVIEW
Kathrine Håland Jeppesen, Sytter Christiansen, Kirsten Frederiksen
OBJECTIVE: The aim of this review was to explore the literature on the connection between teaching strategies and nursing students' learning to clarify which teaching strategies provide optimal learning experiences and outcomes. DATA SOURCES: Sources dating from January 2000 to November 2016 were systematically searched in PubMed, Cinahl, Scopus, Web of Science, ProQuest. METHODS: A systematic literature review was conducted that included quantitative and qualitative studies...
May 13, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28575417/implications-of-electronic-health-record-downtime-an-analysis-of-patient-safety-event-reports
#13
Ethan Larsen, Allan Fong, Christian Wernz, Raj M Ratwani
Objective: We sought to understand the types of clinical processes, such as image and medication ordering, that are disrupted during electronic health record (EHR) downtime periods by analyzing the narratives of patient safety event report data. Materials and Methods: From a database of 80 381 event reports, 76 reports were identified as explicitly describing a safety event associated with an EHR downtime period. These reports were analyzed and categorized based on a developed code book to identify the clinical processes that were impacted by downtime...
May 30, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28572072/the-critical-role-of-cognitive-based-trait-differences-in-transcranial-direct-current-stimulation-tdcs-suppression-of-food-craving-and-eating-in-frank-obesity
#14
Mary Katherine Ray, Maria D Sylvester, Lauren Osborn, Joel Helms, Bulent Turan, Emilee E Burgess, Mary M Boggiano
Obesity remains a major public health concern and novel treatments are needed. Transcranial direct current stimulation (tDCS) is a neuromodulation technique shown to reduce food craving and consumption, especially when targeting the dorsolateral prefrontal cortex (DLPFC) with a right anode/left cathode electrode montage. Despite the implications to treat frank (non-bingeeating) obesity, no study has tested the right anode/left cathode montage in this population. Additionally, most tDCS appetite studies have not controlled for differences in traits under DLPFC control that may influence how well one responds to tDCS...
May 29, 2017: Appetite
https://www.readbyqxmd.com/read/28553262/differing-complex-microbiota-alter-disease-severity-of-the-il-10-mouse-model-of-inflammatory-bowel-disease
#15
Marcia L Hart, Aaron C Ericsson, Craig L Franklin
It is estimated that 1.4 million people in the United States suffer from Inflammatory Bowel Disease (IBD), with an overall annual health care cost of more than $1.7 billion. Although the exact etiology of this disease remains unknown, research suggests that it is a multifactorial disease associated with aberrant gastrointestinal microbial populations (dysbiosis). The C57BL/6 and C3H/HeJBir mouse strains with targeted mutations in the IL-10 gene are commonly used models to study IBD. However, anecdotally, disease phenotype can vary in severity from lab to lab...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28552168/an-experimental-investigation-of-breaking-learnt-habits-with-verbal-implementation-intentions
#16
Aukje A C Verhoeven, Merel Kindt, Colene L Zomer, Sanne de Wit
The interplay between inflexible habits and flexible goal-directed control can be modelled in lab-settings using the slips-of-action task. In this task, participants are required to selectively respond to still-valuable outcomes while suppressing responding towards no-longer valuable outcomes, thereby overriding learned stimulus-response associations. Here we examined in the slips-of-action task whether learnt habits can be changed using a planning technique - so-called implementation intentions - whereby people instruct themselves to enact a certain behaviour (or not) in the presence of a specific critical stimulus...
May 26, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28550123/essential-role-for-histone-deacetylase-11-hdac11-in-neutrophil-biology
#17
Eva Sahakian, Jie Chen, John J Powers, Xianghong Chen, Kamira Maharaj, Susan L Deng, Maritza Lienlaf, Hong Wei Wang, Fengdong Cheng, Andressa L Sodré, Allison Distler, Limin Xing, Patricio Perez-Villarroel, Sheng Wei, Alejandro Villagra, Ed Seto, Eduardo M Sotomayor, Pedro Horna, Javier Pinilla-Ibarz
Epigenetic changes in chromatin structure have been recently associated with the deregulated expression of critical genes in normal and malignant processes. HDAC11, the newest member of the HDAC family of enzymes, functions as a negative regulator of IL-10 expression in APCs, as previously described by our lab. However, at the present time, its role in other hematopoietic cells, specifically in neutrophils, has not been fully explored. In this report, for the first time, we present a novel physiologic role for HDAC11 as a multifaceted regulator of neutrophils...
May 26, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28530770/diagnostic-value-of-appendicular-doppler-ultrasonography-in-acute-appendicitis
#18
Hüseyin Uzunosmanoğlu, Yunsur Çevik, Şeref Kerem Çorbacıoğlu, Emine Akıncı, Hakan Buluş, Kadir Ağladıoğlu
BACKGROUND: Acute appendicitis is one of the most common causes of acute abdominal pain prompting emergency department (ED) visits. It is critical for the physicians to promptly and accurately diagnose acute appendicitis. The present study aimed to evaluate the diagnostic efficacy of Doppler ultrasonography (USG) in patients with acute appendicitis and compare this new method with other commonly used radio-diagnostic tools. METHODS: All patients who were diagnosed with acute appendicitis at the Kecioren Training and Research Hospital ED and later underwent appendectomy between October 2012 and April 2013 were included in the study...
May 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28524117/ebutterfly-leveraging-massive-online-citizen-science-for-butterfly-consevation
#19
Kathleen L Prudic, Kent P McFarland, Jeffrey C Oliver, Rebecca A Hutchinson, Elizabeth C Long, Jeremy T Kerr, Maxim Larrivée
Data collection, storage, analysis, visualization, and dissemination are changing rapidly due to advances in new technologies driven by computer science and universal access to the internet. These technologies and web connections place human observers front and center in citizen science-driven research and are critical in generating new discoveries and innovation in such fields as astronomy, biodiversity, and meteorology. Research projects utilizing a citizen science approach address scientific problems at regional, continental, and even global scales otherwise impossible for a single lab or even a small collection of academic researchers...
May 18, 2017: Insects
https://www.readbyqxmd.com/read/28516300/predicting-surgical-skill-from-the-first-n-seconds-of-a-task-value-over-task-time-using-the-isogony-principle
#20
Anna French, Thomas S Lendvay, Robert M Sweet, Timothy M Kowalewski
PURPOSE: Most evaluations of surgical workflow or surgeon skill use simple, descriptive statistics (e.g., time) across whole procedures, thereby deemphasizing critical steps and potentially obscuring critical inefficiencies or skill deficiencies. In this work, we examine off-line, temporal clustering methods that chunk training procedures into clinically relevant surgical tasks or steps during robot-assisted surgery. METHODS: Features calculated from the isogony principle are used to train four common machine learning algorithms from dry-lab laparoscopic data gathered from three common training exercises...
May 17, 2017: International Journal of Computer Assisted Radiology and Surgery
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