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cholangitis review

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https://www.readbyqxmd.com/read/28229129/sphincterotomy-with-endoscopic-biliary-drainage-for-severe-acute-cholangitis-a-meta-analysis
#1
Tarek Sawas, Noura Arwani, Shadi Al Halabi, John Vargo
Aims To investigate the role of endoscopic sphincterotomy (ES) with endoscopic biliary drainage (EBD) in acute severe obstructive cholangitis management by performing a meta-analysis of controlled trials. Method We searched PubMed and Embase for controlled studies that compared endoscopic drainage with ES versus Non-ES in acute obstructive cholangitis. Two reviewers selected the studies and extracted the data. Disagreement was addressed by a third reviewer. Heterogeneity of the studies was analyzed by Cochran's Q statistics...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28224465/long-term-outcomes-following-percutaneous-cholecystostomy-tube-placement-for-treatment-of-acute-calculous-cholecystitis
#2
Donna Marie L Alvino, Zhi Ven Fong, Colin J McCarthy, George Velmahos, Keith D Lillemoe, Peter R Mueller, Peter J Fagenholz
INTRODUCTION: Percutaneous cholecystostomy tube (PCT) placement is considered a safe alternative to cholecystectomy for the treatment of acute calculous cholecystitis (ACC), but data regarding long-term outcomes following PCT are limited. METHODS: We retrospectively reviewed our institutional experience of patients undergoing PCT for ACC between 1997 and 2015. Recurrent biliary events were defined as cholecystitis, cholangitis, or gallstone pancreatitis. RESULTS: PCT was placed for 288 patients with ACC...
February 21, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28215616/incidence-and-determinants-of-hepatocellular-carcinoma-in-autoimmune-hepatitis-a-systematic-review-and-meta-analysis
#3
REVIEW
Aylin Tansel, Lior H Katz, Hashem B El-Serag, Aaron P Thrift, Mayur Parepally, Mohammad H Shakhatreh, Fasiha Kanwal
BACKGROUND: The risk of hepatocellular carcinoma (HCC) in patients with autoimmune hepatitis (AIH) is unclear. We conducted a systematic review and meta-analysis of the incidence of HCC and associated risk factors among patients with AIH. METHODS: We searched PubMed, Embase, and reference lists from relevant articles through June 2016 to identify cohort studies that examined the incidence of HCC in patients with AIH. We used random effects models to estimate pooled incidence rates overall and in subgroup of patients with cirrhosis...
February 12, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28213923/diagnostic-accuracy-of-charcot-s-triad-a-systematic-review
#4
REVIEW
Steva Rumsey, Joel Winders, Andrew D MacCormick
BACKGROUND: Charcot's triad is a well-established diagnostic tool for acute cholangitis (AC). It has been recognized as an inaccurate test in clinical practice; however, its exact sensitivity and specificity remain unclear. This knowledge is key to informing the value of its continued clinical application. The objectives of this study are to calculate an estimate of the sensitivity and specificity of Charcot's triad based on published research and consider its applicability to clinical practice and medical education...
February 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28176451/epidemiology-and-risk-factors-for-infection-after-living-donor-liver-transplantation
#5
Cybele Lara R Abad, Brian D Lahr, Raymund R Razonable
BACKGROUND: The epidemiology of infections after living donor liver transplantation is limited. We aimed to study the epidemiology and risk factors of infections after living donor liver transplantation. METHODS: The medical records of 223 adult patients who underwent living donor liver transplantation from January 1, 2000 - August 31, 2015 were reviewed for all infections occurring up to 1 year. We estimated the cumulative incidence of infection using the Kaplan Meier product limit method...
February 8, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28165852/current-approach-to-the-diagnosis-of-igg4-related-disease-combination-of-comprehensive-diagnostic-and-organ-specific-criteria
#6
Hisanori Umehara, Kazuichi Okazaki, Takuji Nakamura, Tomomi Satoh-Nakamura, Akio Nakajima, Mitsuhiro Kawano, Tsuneyo Mimori, Tsutomu Chiba
IgG4-related disease (IgG4-RD) is a fascinating clinical entity proposed by Japanese investigators, and includes a wide variety of diseases, formerly diagnosed as Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis, retroperitoneal fibrosis, etc. Although all clinicians in every field of medicine may encounter this new disease, a unifying diagnostic criteria has not been established. In 2011, the Japanese IgG4 team, organized by the Ministry of Health, Labor and Welfare (MHLW) of Japan, published comprehensive diagnostic criteria for IgG4-RD...
February 6, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28165825/chemoprevention-of-colorectal-cancer-in-ulcerative-colitis-digging-deep-in-current-evidence
#7
Cristina Bezzio, Stefano Festa, Simone Saibeni, Claudio Papi
Patients with ulcerative colitis (UC) have an increased risk of developing colorectal cancer (CRC). Surveillance colonoscopy is currently recommended for patients with long-standing extensive colitis for reducing CRC risk. Chemoprevention is an attractive complementary strategy. Areas covered: Inflammation is a major determinant of CRC risk and is potentially modifiable. Reducing inflammation is supposed to reduce CRC risk. Several medications have been evaluated in this setting: 5-ASA, thiopurines, anti-TNFα agents and ursodeoxycholic acid (UCDA) in patients with associated primary sclerosing cholangitis (PSC)...
February 6, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28154911/comparative-performance-of-non-contrast-mri-with-haste-vs-contrast-enhanced-mri-3d-mrcp-for-possible-choledocholithiasis-in-hospitalized-patients
#8
Stella K Kang, Laura Heacock, Ankur M Doshi, Justin R Ream, Jeffrey Sun, James S Babb
PURPOSE: To compare the performance of non-contrast MRI with half-Fourier acquisition single-shot turbo spin echo (HASTE) vs. contrast-enhanced MRI/3D-MRCP for assessment of suspected choledocholithiasis in hospitalized patients. METHODS AND MATERIALS: 123 contrast-enhanced abdominal MRI/MRCP scans in the hospital setting for possible choledocholithiasis were retrospectively evaluated. Endoscopic retrograde cholangiopancreatography, intraoperative cholangiogram or documented clinical resolution served as the reference standard...
February 2, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28153785/aortic-and-splanchnic-artery-aneurysms-unusual-causes-of-biliary-obstruction-a-retrospective-cohort-from-literature
#9
REVIEW
Kevin Tin, Zain A Sobani, Joel Horovitz, Rabin Rahmani
Mechanical obstruction of the biliary tree and resultant stasis are the cornerstone of a spectrum of diseases ranging from biliary colic to fulminant cholangitis. Infrequently acquired abnormalities of the abdominal vasculature can lead to biliary obstruction. In 2010, we reported a case of acute cholangitis resulting from compression of extra hepatic bile duct by an abdominal aortic aneurysm (AAA). We subsequently conducted a follow up scoping review of literature to identify other cases of acquired abdominal arterial abnormalities resulting in biliary obstruction looking at their management and outcomes...
January 30, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28146445/risk-of-cholangiocarcinoma-in-patients-with-primary-sclerosing-cholangitis-diagnosis-and-surveillance
#10
Hanno Ehlken, Roman Zenouzi, Christoph Schramm
PURPOSE OF REVIEW: Primary sclerosing cholangitis (PSC) is associated with an increased risk of hepatobiliary and extrahepatic malignancy. Particularly the risk of cholangiocarcinoma (CCA) is greatly increased. To provide potentially curative treatments for affected patients an early diagnosis of CCA is crucial. We here review the current advances with respect to CCA diagnosis and surveillance and discuss a rational approach on how to perform surveillance of CCA in PSC patients. RECENT FINDINGS: Given the shortcomings of the current modalities for the surveillance and diagnosis of CCA in PSC, recent studies have focused on novel biomarkers for CCA...
March 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28128682/percutaneous-cholecystocentesis-in-cats-with-suspected-hepatobiliary-disease
#11
Victoria L Byfield, Julie E Callahan Clark, Bradley J Turek, Charles W Bradley, Mark P Rondeau
Objectives The objective was to evaluate the safety and diagnostic utility of percutaneous ultrasound-guided cholecystocentesis (PUC) in cats with suspected hepatobiliary disease. Methods Medical records of 83 cats with suspected hepatobiliary disease that underwent PUC were retrospectively reviewed. Results At the time of PUC, at least one additional procedure was performed in 79/83 cats, including hepatic aspiration and/or biopsy (n = 75) and splenic aspiration (n = 18). Complications were noted in 14/83 cases, including increased abdominal fluid (n = 11), needle-tip occlusion (n = 1), failed first attempt to penetrate the gall bladder wall (n = 1) and pneumoperitoneum (n = 1)...
January 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28124661/hypergammaglobulinemia-is-a-marker-of-extraintestinal-manifestations-in-pediatric-inflammatory-bowel-disease
#12
Manar Matar, Firas Rinawi, Raanan Shamir, Amit Assa
BACKGROUND/AIMS: The significance of hypergammaglobulinemia as a phenotypic feature of inflammatory bowel disease is unknown. Thus, we aimed to analyze the magnitude and significance of hypergammaglobulinemia in newly diagnosed pediatric inflammatory bowel disease patients. MATERIALS AND METHODS: The medical records of 296 pediatric onset inflammatory bowel disease patients who were evaluated from 2002 to 2015 were retrospectively reviewed. Patients with recorded immunoglobulin G (IgG) levels were categorized as either normal or high IgG levels at diagnosis...
January 26, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28124078/primary-biliary-cholangitis-associated-with-skin-disorders-a-case-report-and-review-of-the-literature
#13
REVIEW
Benedetta Terziroli Beretta-Piccoli, Caroline Guillod, Igor Marsteller, Roland Blum, Luca Mazzucchelli, Chiara Mondino, Pietro Invernizzi, M Eric Gershwin, Carlo Mainetti
Primary biliary cholangitis (PBC) is a rare autoimmune cholestatic liver disease. It is often associated with extrahepatic autoimmune diseases. Skin disorders are sporadically reported in association with PBC. We report an unusual case of PBC associated with acquired reactive perforating dermatosis (ARPD) and present a review of the literature on skin disorders associated with PBC. Our patient presented to the dermatology department with generalized pruritus associated with nodular perforating skin lesions on the trunk, and cholestatic liver disease of unknown origin...
January 25, 2017: Archivum Immunologiae et Therapiae Experimentalis
https://www.readbyqxmd.com/read/28123244/are-self-expandable-metal-stents-superior-to-plastic-stents-in-palliating-malignant-distal-biliary-strictures-a-meta-analysis-and-systematic-review
#14
Harsha Moole, Amy Jaeger, Micheal Cashman, Fritz H Volmar, Sonu Dhillon, Mathew L Bechtold, Srinivas R Puli
BACKGROUND: Palliation for inoperable malignant distal biliary strictures can be achieved with self-expandable metal stents (SEMS) and plastic stents (PS). This is a meta-analysis to compare PS and SEMS. The aim of the study is to compare clinical outcomes in patients with SEMS and PS. METHODS: Study selection criteria were studied using SEMS and PS for palliation in patients with malignant distal biliary stricture. For data collection and extraction, articles were searched in Ovid journals, Medline, Cochrane database, and Pubmed...
January 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28115492/are-random-biopsies-still-useful-for-the-detection-of-neoplasia-in-patients-with-ibd-undergoing-surveillance-colonoscopy-with-chromoendoscopy
#15
Driffa Moussata, Matthieu Allez, Dominique Cazals-Hatem, Xavier Treton, David Laharie, Jean-Marie Reimund, Philippe Bertheau, Arnaud Bourreille, Anne Lavergne-Slove, Hedia Brixi, Julien Branche, Jean-Marc Gornet, Carmen Stefanescu, Jacques Moreau, Philippe Marteau, Anne-Laure Pelletier, Franck Carbonnel, Philippe Seksik, Marion Simon, Jean-François Fléjou, Jean-Fréderic Colombel, Anne-Laure Charlois, Xavier Roblin, Stéphane Nancey, Yoram Bouhnik, Françoise Berger, Bernard Flourié
BACKGROUND: Colonoscopy with pan-chromoendoscopy (CE) is superior to standard colonoscopy in detecting neoplasia in patients with IBD. Performing random biopsies in unsuspicious mucosa after CE remains controversial. METHODS: Consecutive patients with IBD who underwent surveillance colonoscopy using CE were prospectively included. The standardised procedure used CE, performed targeted biopsies or endoscopic resection on suspicious lesions and then quadrant random biopsies every 10 cm...
January 23, 2017: Gut
https://www.readbyqxmd.com/read/28106105/autoimmune-hepatitis-review-of-histologic-features-included-in-the-simplified-criteria-proposed-by-the-international-autoimmune-hepatitis-group-and-proposal-for-new-histologic-criteria
#16
Dana Balitzer, Nafis Shafizadeh, Marion G Peters, Linda D Ferrell, Najeeb Alshak, Sanjay Kakar
Simplified criteria for diagnosis of autoimmune hepatitis are based on autoantibodies, serum immunoglobulin G, histologic features, and negative viral serology. A score of 6 points is necessary for the designation of probable autoimmune hepatitis and 7 points or more for definite autoimmune hepatitis. The presence of three histologic features is required for categorizing a case as typical (2 points): interface hepatitis with portal lymphocytic/lymphoplasmacytic cells extending into lobule, emperipolesis, and rosettes...
January 20, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28105582/-control-of-opisthorchis-viverrini-infection-for-cholangiocarcinoma-prevention
#17
Y Buisson
The International Agency for Research on Cancer (IARC) has classified two liver flukes as carcinogenic to humans (Group 1): Opisthorchis viverrini in 1994 and Clonorchis sinensis in 2009. This review is focused on O. viverrini, the most studied of these two trematodes, which infects nearly 10 million people in Southeast Asia. The life cycle involves two intermediate hosts living in fresh water: a snail of the genus Bithynia and a ciprinid fish. The definitive hosts (human, cat, dog) become infected by ingesting raw fish containing metacercariae, the infective stage of the parasite...
January 19, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28077782/serum-and-tissue-markers-in-hepatocellular-carcinoma-and-cholangiocarcinoma-clinical-and-prognostic-implications
#18
REVIEW
Massimiliano Berretta, Carla Cavaliere, Lara Alessandrini, Brigida Stanzione, Gaetano Facchini, Luca Balestreri, Tiziana Perin, Vincenzo Canzonieri
HCC represents the sixth most common cancer worldwide and the second leading cause of cancer-related death. Despite the high incidence, treatment options for advanced HCC remain limited and unsuccessful, resulting in a poor prognosis. Despite the major advances achieved in the diagnostic management of HCC, only one third of the newly diagnosed patients are presently eligible for curative treatments. Advances in technology and an increased understanding of HCC biology have led to the discovery of novel biomarkers...
December 14, 2016: Oncotarget
https://www.readbyqxmd.com/read/28070877/idiopathic-retroperitoneal-fibrosis-and-its-overlap-with-igg4-related-disease
#19
REVIEW
Giovanni Maria Rossi, Rossana Rocco, Eugenia Accorsi Buttini, Chiara Marvisi, Augusto Vaglio
Retroperitoneal fibrosis (RPF) is a rare disease characterised by fibrous tissue proliferation in the retroperitoneum, with encasement of the ureters and large vessels of the abdomen as the most destructive of potentially severe complications. It can either be idiopathic, or secondary to infections, malignancies, or the use of certain drugs. The idiopathic form accounts for approximately 75% of the cases, and is usually responsive to immunosuppressive therapy. In recent years, the emergence of a new clinical entity, IgG4-related disease (IgG4-RD), shed light on many fibro-inflammatory disorders once thought to be separate clinical entities, although frequently associated in the so-called multifocal fibrosclerosis...
January 9, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28052628/management-of-cholestatic-disease-in-2017
#20
REVIEW
Elsemieke de Vries, Ulrich Beuers
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the most frequent chronic cholestatic liver diseases and serve as model diseases to discuss the management of cholestasis in 2017 in the lecture that is summarized in this report. PBC and PSC are characterized by inflammation and fibrosis of small intrahepatic (PBC) or larger intra- and/or extrahepatic (PSC) bile ducts. Bile duct damage leads to cholestasis and can progress to liver fibrosis and even cirrhosis. Various genetic, environmental and endogenous factors may contribute to the development of chronic cholestatic liver diseases, but the exact pathogenesis of PBC and PSC has not been clarified...
January 2017: Liver International: Official Journal of the International Association for the Study of the Liver
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