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https://www.readbyqxmd.com/read/29355161/pre-and-post-ductal-oxygen-saturation-among-apparently-healthy-low-birth-weight-neonates
#1
Leo A Odudu, Beatrice N Ezenwa, Christopher I Esezobor, Ekanem N Ekure, Mathias T C Egri Okwaji, Chinyere V Ezeaka, Fidelis O Njokanma, Jejelola Ladele
INTRODUCTION: Reference values of oxygen saturation (SpO2) to guide care of low birth weight neonates have been obtained mainly from Caucasians. Data from African newborns are lacking. To determine the pre- and post-ductal SpO2values of low birth weight neonates within the first 72 h of life, compare SpO2values of moderate-late preterm and term low birth weight neonates and determine how mode of delivery affected SpO2in the first 24 h of life. METHODOLOGY: An observational descriptive study was carried out on apparently healthy low birth weight newborns weighing 1500 to ≤2499 g...
October 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29350401/neurodevelopmental-outcome-in-very-preterm-and-very-low-birthweight-infants-born-over-the-past-decade-a-meta-analytic-review
#2
REVIEW
Aurelie Pascal, Paul Govaert, Ann Oostra, Gunnar Naulaers, Els Ortibus, Christine Van den Broeck
AIM: The purpose of this systematic review was to provide an up-to-date global overview of the separate prevalences of motor and cognitive delays and cerebral palsy (CP) in very preterm (VPT) and very-low-birthweight (VLBW) infants. METHOD: A comprehensive search was conducted across four databases. Cohort studies reporting the prevalence of CP and motor or cognitive outcome from 18 months corrected age until 6 years of VPT or VLBW infants born after 2006 were included...
January 19, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29333811/neonatal-mortality-and-associated-factors-in-newborn-infants-admitted-to-a-neonatal-care-unit
#3
Juan C Lona Reyes, René O Pérez Ramírez, Leonardo Llamas Ramos, Larissa M Gómez Ruiz, Edith A Benítez Vázquez, Virginia Rodríguez Patino
INTRODUCTION: The increasing survival rate of preterm infants has altered the epidemiology of neonatal diseases; however, neonatal mortality is still the main component of child mortality. The objective of this study was to evaluate neonatal mortality and associated factors in newborn infants admitted to a neonatal care unit. MATERIAL AND METHODS: Prospective cohort study conducted between January 2016 and January 2017 at Hospital Civil de Guadalajara "Dr. Juan I...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333635/the-changing-relationship-between-bronchopulmonary-dysplasia-and-cognition-in-very-preterm-infants
#4
Jane E Brumbaugh, Tarah T Colaizy, Neel M Patel, Jonathan M Klein
AIM: To characterize the relationship between bronchopulmonary dysplasia (BPD) severity and cognition in the post-surfactant era. METHODS: This was a single-center retrospective analysis of a cohort of infants born 2009-2012. Inclusion criteria were: admission within 48 hours of birth, gestational age 22-0/7-31-6/7 weeks, birth weight 400-1500 g, and Bayley Scales of Infant and Toddler Development-III testing at 18-26 months corrected age. Infants (n=151) were classified by BPD severity with the NIH Workshop definition...
January 15, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29321180/two-year-neurodevelopmental-outcomes-of-extremely-preterm-infants-treated-with-early-hydrocortisone-treatment-effect-according-to-gestational-age-at-birth
#5
Olivier Baud, Clémence Trousson, Valérie Biran, Emilie Leroy, Damir Mohamed, Corinne Alberti
OBJECTIVE: To determine whether early hydrocortisone treatment in extremely preterm infants affects neurodevelopmental outcomes at 2 years of age according to gestational age at birth. PATIENTS AND METHODS: This is an exploratory analysis of neurodevelopmental outcomes by gestational age strata from the PREMILOC trial, in which patients were randomly assigned to receive either placebo or low-dose hydrocortisone and randomisation was stratified by gestational age groups (24-25 and 26-27 weeks of gestation)...
January 10, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29306493/delivery-room-resuscitation-and-short-term-outcomes-in-moderately-preterm-infants
#6
Monika Bajaj, Girija Natarajan, Seetha Shankaran, Myra Wyckoff, Abbot R Laptook, Edward F Bell, Barbara J Stoll, Waldemar A Carlo, Betty R Vohr, Shampa Saha, Krisa P Van Meurs, Pablo J Sanchez, Carl T D'Angio, Rosemary D Higgins, Abhik Das, Nancy Newman, Michele C Walsh
OBJECTIVES: To describe the frequency and extent of delivery room resuscitation and evaluate the association of delivery room resuscitation with neonatal outcomes in moderately preterm (MPT) infants. STUDY DESIGN: This was an observational cohort study of MPT infants delivered at 290/7 to 336/7 weeks' gestational age (GA) enrolled in the Neonatal Research Network MPT registry. Infants were categorized into 5 groups based on the highest level of delivery room intervention: routine care, oxygen and/or continuous positive airway pressure, bag and mask ventilation, endotracheal intubation, and cardiopulmonary resuscitation including chest compressions and/or epinephrine use...
January 3, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29301912/monitoring-the-postnatal-growth-of-preterm-infants-a-paradigm-change
#7
REVIEW
Jose Villar, Francesca Giuliani, Fernando Barros, Paola Roggero, Irma Alejandra Coronado Zarco, Maria Albertina S Rego, Roseline Ochieng, Maria Lorella Gianni, Suman Rao, Ann Lambert, Irina Ryumina, Carl Britto, Deepak Chawla, Leila Cheikh Ismail, Syed Rehan Ali, Jane Hirst, Jagjit Singh Teji, Karim Abawi, Jacqueline Asibey, Josephine Agyeman-Duah, Kenny McCormick, Enrico Bertino, Aris T Papageorghiou, Josep Figueras-Aloy, Zulfiqar Bhutta, Stephen Kennedy
There is no consensus regarding how the growth of preterm infants should be monitored or what constitutes their ideal pattern of growth, especially after term-corrected age. The concept that the growth of preterm infants should match that of healthy fetuses is not substantiated by data and, in practice, is seldom attained, particularly for very preterm infants. Hence, by hospital discharge, many preterm infants are classified as postnatal growth-restricted. In a recent systematic review, 61 longitudinal reference charts were identified, most with considerable limitations in the quality of gestational age estimation, anthropometric measures, feeding regimens, and how morbidities were described...
January 4, 2018: Pediatrics
https://www.readbyqxmd.com/read/29282354/using-polyethylene-plastic-bag-to-prevent-moderate-hypothermia-during-transport-in-very-low-birth-weight-infants-a-randomized-trial
#8
Xiao-Jing Hu, Li Wang, Ru-Yi Zheng, Tian-Chan Lv, Yu-Xia Zhang, Yun Cao, Guo-Ying Huang
OBJECTIVE: Hypothermia remains a significant problem among very low birth weight (VLBW) infants. The use of occlusive polyethylene plastic bags immediately after birth has been proven to be effective for preterm infants to reduce hypothermia. This study aims to determine whether placing VLBW infants in plastic bags during transport reduces hypothermia. STUDY DESIGN: Study infants were randomly assigned to a standard thermoregulation protocol or to a standard thermoregulation protocol with placement of the torso and lower extremities inside a polyethylene plastic bag during transport...
December 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29282094/nasal-high-flow-therapy-in-very-low-birth-weight-infants-with-mild-respiratory-distress-syndrome-a-single-center-experience
#9
Antonio Di Mauro, Manuela Capozza, Sergio Cotugno, Silvio Tafuri, Francesco Paolo Bianchi, Federico Schettini, Raffaella Panza, Nicola Laforgia
BACKGROUND: Pulmonary disorders and respiratory failure represent one of the most common morbidities of preterm newborns admitted to neonatal intensive care units (NICUs). The use of nasal high-flow therapy (nHFT) has been more recently introduced into the NICUs as a non-invasive respiratory (NIV) support. METHODS: We performed a retrospective study to evaluate safety and effectiveness of nHFT as primary support for infants born < 29 weeks of gestation and/or VLBW presenting with mild Respiratory Distress Syndrome (RDS)...
December 28, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29261723/shifting-the-boundaries-for-early-caffeine-initiation-in-neonatal-practice-results-of-a-prospective-multicenter-study-on-very-preterm-infants-with-respiratory-distress-syndrome
#10
MULTICENTER STUDY
Maria Katarzyna Borszewska-Kornacka, Roman Hożejowski, Magdalena Rutkowska, Ryszard Lauterbach
BACKGROUND: There is growing evidence that supports the benefits of early use of caffeine in preterm neonates with RDS; however, no formal recommendations specifying the exact timing of therapy initiation have been provided. OBJECTIVES: We compared neonatal outcomes in infants receiving early (initial dose on the 1st day of life) and late (initial dose on day 2+ of life) caffeine therapy. METHODS: Using data from a prospective, cohort study, we identified 986 infants ≤32 weeks' gestation with RDS and assessed the timing of caffeine therapy initiation, need for ventilatory support, mortality and incidence of typical complications of prematurity...
2017: PloS One
https://www.readbyqxmd.com/read/29249398/impact-of-structured-programs-on-breastfeeding-initiation-rates-in-preterm-neonates-in-a-socioeconomically-deprived-area-in-france-a-10-year-population-based-study
#11
M-L Charkaluk, H Bomy, S Delguste, M Courdent, S Rousseau, C Zaoui-Grattepanche, V Pierrat
Structured programs have a positive impact on breastfeeding (BF) but have rarely been evaluated for preterm neonates, frequently combining prematurity and socioeconomic deprivation as risk factors of a low BF rate. We aimed to assess BF initiation rates in very preterm (<33 weeks' gestational age), moderately preterm (33-36 weeks), and term neonates from 2002 to 2011 in a French administrative district characterized by socioeconomic deprivation. Structured activities to promote and support BF have been implemented in this area since 2002; they all started in neonatal units...
December 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29246824/association-of-very-preterm-birth-with-decreased-risk-of-eczema-a-systematic-review-and-meta-analysis
#12
Tingting Zhu, Jing Zhao, Yi Qu, Li Zhang, Dezhi Mu
BACKGROUND: Accumulating studies suggest that an association exists between preterm birth and eczema. OBJECTIVE: We performed a meta-analysis of the available evidence to determine whether the risk of developing eczema is affected by preterm birth. METHODS: We searched for observational studies using PubMed, Cochrane Library, Web of Science, and EMBASE databases from inception to February 1, 2017. Studies that met the inclusion criteria were included...
December 12, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29246467/a-randomized-clinical-trial-of-umbilical-cord-milking-vs-delayed-cord-clamping-in-preterm-infants-neurodevelopmental-outcomes-at-22-26-months-of-corrected-age
#13
Anup Katheria, Donna Garey, Giang Truong, Natacha Akshoomoff, Jane Steen, Mauricio Maldonado, Debra Poeltler, Mary Jane Harbert, Yvonne E Vaucher, Neil Finer
OBJECTIVE: To compare the effect of umbilical cord milking vs delayed cord clamping (DCC) on neurodevelopmental and health outcomes in very preterm infants at 22-26 months of corrected age. STUDY DESIGN: Neurodevelopmental outcomes at 2 years of age were assessed using the Bayley Scales of Infant Development, third edition, and a standardized neurologic examination. Data regarding pulmonary morbidities, neurosensory impairments, and hospitalizations were obtained by parental interview...
December 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29246358/admission-temperature-and-associated-mortality-and-morbidity-among-moderately-and-extremely-preterm-infants
#14
Abbot R Laptook, Edward F Bell, Seetha Shankaran, Nansi S Boghossian, Myra H Wyckoff, Sarah Kandefer, Michele Walsh, Shampa Saha, Rosemary Higgins
OBJECTIVE: To evaluate the temperature distribution among moderately preterm (MPT, 29-33 weeks) and extremely preterm (EPT, <29 weeks) infants upon neonatal intensive care unit (NICU) admission in 2012-2013, the change in admission temperature distribution for EPT infants between 2002-2003 and 2012-2013, and associations between admission temperature and mortality and morbidity for both MPT and EPT infants. STUDY DESIGN: Prospectively collected data from 18 centers in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network were used to examine NICU admission temperature of inborn MPT and EPT infants...
January 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29242570/monitoring-cerebral-oxygenation-of-preterm-infants-using-a-neonatal-specific-sensor
#15
M Kenosi, J M O'Toole, G A Hawkes, W Hutch, E Low, M Wall, G B Boylan, C A Ryan, E M Dempsey
INTRODUCTION: Cerebral oxygenation (rcSO2) monitoring in preterm infants may identify periods of cerebral hypoxia or hyperoxia. We hypothesised that there was a relationship between rcSO2 values and short term outcome in infants of GA < 32weeks. METHODS: RcSO2 values were recorded for the first 48 h of life using an INVOS monitor with a neonatal sensor. The association between cranial ultrasound scan measured brain injury and rcSO2 was assessed. RESULTS: 120 infants were included...
December 15, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29242268/preterm-birth-poverty-and-cognitive-development
#16
Jennifer L Beauregard, Carolyn Drews-Botsch, Jessica M Sales, W Dana Flanders, Michael R Kramer
BACKGROUND: Preterm birth and childhood poverty each adversely impact children's cognitive development and academic outcomes. In this study, we investigated whether the relationships between preterm and early term birth and children's cognitive scores at 3, 5, and 7 years old were modified by childhood poverty. METHODS: This study was conducted by using data on singletons born at 24 to 40 weeks' gestation enrolled in the Millennium Cohort Study in the United Kingdom...
December 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/29223898/exposure-to-low-concentrations-of-air-pollutants-and-adverse-birth-outcomes-in-brisbane-australia-2003-2013
#17
Gongbo Chen, Yuming Guo, Michael J Abramson, Gail Williams, Shanshan Li
BACKGROUND: It's unclear whether exposures to low-level air pollution have adverse effects on birth outcomes, and which trimester-specific pregnant exposure is sensitive. OBJECTIVES: To investigate the effects of maternal exposure during each trimester and the whole pregnancy to particles with aerodynamic diameter<2.5μm (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) on preterm birth (PTB) and low birth weight (LBW). METHODS: Daily data on birth records, air quality, and weather conditions were collected in Brisbane, Australia during 2003-2013...
December 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29210924/intraventricular-hemorrhage-in-moderate-to-severe-congenital-heart-disease
#18
Cynthia M Ortinau, Jagruti S Anadkat, Christopher D Smyser, Pirooz Eghtesady
OBJECTIVES: Determine the prevalence of intraventricular hemorrhage in infants with moderate to severe congenital heart disease, investigate the impact of gestational age, cardiac diagnosis, and cardiac intervention on intraventricular hemorrhage, and compare intraventricular hemorrhage rates in preterm infants with and without congenital heart disease. DESIGN: A single-center retrospective review. SETTING: A tertiary care children's hospital...
January 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29208662/antenatal-corticosteroids-in-impending-preterm-deliveries-before-25-weeks-gestation
#19
Mangesh Deshmukh, Sanjay Patole
Antenatal corticosteroid (ANC) use before 25 weeks' gestation is controversial. Our previous systematic review (eight observational studies, n=10 109) showed that ANC exposure was associated with significantly reduced mortality and severe intraventricular haemorrhage (IVH)/periventricular leukomalacia (PVL) in neonates born <25 weeks. We update our review by adding data (n=3334) from a recent study. We used Cochrane methodology and summarised the results using GRADE (The Grading of Recommendations Assessment, Development and Evaluation) guidelines...
December 5, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29207214/feed-thickener-for-infants-up-to-six-months-of-age-with-gastro-oesophageal-reflux
#20
REVIEW
T'ng Chang Kwok, Shalini Ojha, Jon Dorling
BACKGROUND: Gastro-oesophageal reflux (GOR) is common in infants, and feed thickeners are often used to manage it in infants as they are simple to use and perceived to be harmless. However, conflicting evidence exists to support the use of feed thickeners. OBJECTIVES: To evaluate the use of feed thickeners in infants up to six months of age with GOR in terms of reduction in a) signs and symptoms of GOR, b) reflux episodes on pH probe monitoring or intraluminal impedance or a combination of both, or c) histological evidence of oesophagitis...
December 5, 2017: Cochrane Database of Systematic Reviews
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