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screening motor development

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https://www.readbyqxmd.com/read/29333806/asq-3-validation-of-the-ages-and-stages-questionnaire-for-the-detection-of-neurodevelopmental-disorders-in-argentine-children
#1
Ana M Romero Otalvaro, Nora Grañana, Nadia Gaeto, María de Los Á Torres, María N Zamblera, María A Vasconez, Claudia Misenta, María E Rouvier, Jane Squires
INTRODUCTION: The systematic assessment of child development in the first years of life is an essential component of pediatric health checkups. The Ages and Stages Questionnaire, third edition (ASQ-3) is the most validated scale, and has been recommended by the UNICEF to verify if children have a normal neurological development. It is a monitoring instrument to assess the main developmental areas, including communication, gross motor, fine motor, personal-social, and problem solving skills, and to compare the local population to the international development standards...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333611/cognitive-dysfunction-after-generalized-tonic-clonic-status-epilepticus-in-adults
#2
K N Power, A Gramstad, N E Gilhus, K O Hufthammer, B A Engelsen
OBJECTIVES: Generalized tonic-clonic status epilepticus (GTC-SE) is considered a risk for cognitive impairment. Research with standardized tools is scarce and non-conclusive. We systematically assessed short-term and long-term cognitive function after GTC-SE. MATERIALS AND METHODS: Thirty-three patients were tested after the clinical post-ictal phase of GTC-SE (timepoint 1) and again after 1 year (timepoint 2). Twenty controls were examined with the same tests...
January 14, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29331789/anticonvulsant-activities-of-%C3%AE-asaronol-e-3-hydroxyasarone-an-active-constituent-derived-from-%C3%AE-asarone
#3
Xirui He, Yajun Bai, Min Zeng, Zefeng Zhao, Qiang Zhang, Ning Xu, Fanggang Qin, Xiaoyang Wei, Meimei Zhao, Ni Wu, Zehua Li, Yajun Zhang, Tai-Ping Fan, Xiaohui Zheng
BACKGROUND: Epilepsy is one of chronic neurological disorders that affects 0.5-1.0% of the world's population during their lifetime. There is a still significant need to develop novel anticonvulsant drugs that possess superior efficacy, broad spectrum of activities and good safety profile. METHODS: α-Asaronol and two current antiseizure drugs (α-asarone and carbamazepine (CBZ)) were assessed by in vivo anticonvulsant screening with the three most employed standard animal seizure models, including maximal electroshock seizure (MES), subcutaneous injection-pentylenetetrazole (PTZ)-induced seizures and 3-mercaptopropionic acid (3-MP)-induced seizures in mice...
August 31, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29330315/outcome-of-preterm-infants-with-postnatal-cytomegalovirus-infection
#4
Julia Gunkel, Linda S de Vries, Marian Jongmans, Corine Koopman-Esseboom, Ingrid C van Haastert, Maria C J Eijsermans, Carolien van Stam, Bert G A van Zanten, Tom F W Wolfs, Joppe Nijman
OBJECTIVES: To assess whether preterm infants with postnatal cytomegalovirus infection develop neurologic sequelae in early childhood. METHODS: Infants <32 weeks' gestation were prospectively screened for cytomegalovirus (CMV) at term-equivalent age. Neurodevelopment was compared between CMV-positive and CMV-negative infants by using the Griffiths Mental Development Scales (GMDS) at 16 months' corrected age (CA); the Bayley Scales of Infant and Toddler Development, Third Edition or the GMDS at 24 to 30 months' CA; and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition and Movement Assessment Battery for Children, Second Edition at 6 years of age...
January 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29311675/sensorimotor-abilities-predict-on-field-performance-in-professional-baseball
#5
Kyle Burris, Kelly Vittetoe, Benjamin Ramger, Sunith Suresh, Surya T Tokdar, Jerome P Reiter, L Gregory Appelbaum
Baseball players must be able to see and react in an instant, yet it is hotly debated whether superior performance is associated with superior sensorimotor abilities. In this study, we compare sensorimotor abilities, measured through 8 psychomotor tasks comprising the Nike Sensory Station assessment battery, and game statistics in a sample of 252 professional baseball players to evaluate the links between sensorimotor skills and on-field performance. For this purpose, we develop a series of Bayesian hierarchical latent variable models enabling us to compare statistics across professional baseball leagues...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29303799/open-access-electronic-diary-for-motor-fluctuation-and-dyskinesia-evaluation-in-parkinson-disease-comparison-with-paper-diary
#6
Cinthia Terroba-Chambi, Veronica Bruno, Alex Medina-Escobar, Federico Nanni, Daniel Cerquetti, Malco Rossi, Marcelo Merello
OBJECTIVE: To determine the utility of an electronic diary for registering motor fluctuations and dyskinesia in Parkinson disease (PD). METHODS: Free, open-access touch screen software suitable for Android 4.4 or higher, with medication alarms, adjustable intervals, and medication dose settings was developed to evaluate ON-OFF periods and dyskinesia. Prospective evaluation included a first phase conducted to make adjustments concerning motor limitations when using the tablet, as well as for proper motor complication identification, and a second phase of 3 days of use at home with a prior diary training session comparing a modified paper version of Core Assessment Program for Surgical Interventional Therapies in PD and the electronic diary...
January 5, 2018: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/29302199/cell-to-cell-transmission-of-polyglutamine-aggregates-in-c-elegans
#7
Dong-Kyu Kim, Kyu-Won Cho, Woo Jung Ahn, Dayana Perez-Acuña, Hyunsu Jeong, He-Jin Lee, Seung-Jae Lee
Huntington disease (HD) is an inherited neurodegenerative disorder characterized by motor and cognitive dysfunction caused by expansion of polyglutamine (polyQ) repeat in exon 1 of huntingtin (HTT). In patients, the number of glutamine residues in polyQ tracts are over 35, and it is correlated with age of onset, severity, and disease progression. Expansion of polyQ increases the propensity for HTT protein aggregation, process known to be implicated in neurodegeneration. These pathological aggregates can be transmitted from neuron to another neuron, and this process may explain the pathological spreading of polyQ aggregates...
December 2017: Experimental Neurobiology
https://www.readbyqxmd.com/read/29251514/validity-of-a-novel-touch-screen-tablet-based-assessment-for-mild-cognitive-impairment-and-probable-ad-in-older-adults
#8
Yo-Ping Huang, Avichandra Singh, Sheng Chen, Fang-Ju Sun, Chiu-Ron Huang, Shen-Ing Liu
This study aimed to develop a psychometrically valid touch screen tablet-based cognitive test battery to identify early cognitive impairment due to dementia in older adults. The battery includes eight tests with 13 subscores, evaluating visual attention, auditory attention, information processing speed, visual memory, motor control, and visuospatial perception. Among the participants, 43 had been diagnosed with mild cognitive impairment (MCI) and 36 with probable Alzheimer's disease (AD); 41 had no cognitive impairment...
December 1, 2017: Assessment
https://www.readbyqxmd.com/read/29242978/animal-models-of-l-dopa-induced-dyskinesia-the-6-ohda-lesioned-rat-and-mouse
#9
REVIEW
Elisabetta Tronci, Veronica Francardo
Appearance of L-DOPA-induced dyskinesia (LID) represents a major limitation in the pharmacological therapy with the dopamine precursor L-DOPA. Indeed, the vast majority of parkinsonian patients develop dyskinesia within 9-10 years of L-DOPA oral administration. This makes the discovery of new therapeutic strategies an important need. In the last decades, several animal models of Parkinson's disease (PD) have been developed, to both study mechanisms underlying PD pathology and treatment-induced side effects (i...
December 14, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29239998/seasonal-changes-in-functional-fitness-and-neurocognitive-assessments-in-youth-ice-hockey-players
#10
Michelle Avery, Nick Wattie, Michael Holmes, Shilpa Dogra
Deficits in balance and strength combined with differing rates of sensory and motor neural development may increase risk of sports related injury in youth. This study evaluated changes in functional fitness and concussion status over the course of a competitive season in youth ice-hockey players, and examined the relationship between these variables and injury occurrence. Thirty-six participants (8.9 ± 1.1 years) completed pre and post-season assessments including anthropometric measurements, the Functional Movement Screen (FMS), Lower Quarter Y-Balance Test (YBT-LQ), and a computerized neurocognitive assessment (ImPACT)...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29237549/modeling-parkinson-s-disease-and-treatment-complications-in-rodents-potentials-and-pitfalls-of-the-current-options
#11
REVIEW
Veronica Francardo
Animal models of neurological deficits are essential to assess new therapeutic options and reduce treatment complications. Over the last decades, several rodent models of Parkinson's disease have been developed, and have now become the first-line experimental tool for therapeutic screening purposes. Which model is the most predictive for identifying the efficacy of symptomatic or disease-modifying interventions is still a matter of debate. None of the models so far available is able to recapitulate all the features of the human disease, but several well-characterized models with complementary features currently provide a valuable repertoire of tools to address specific scientific hypotheses...
December 10, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29237523/-clinical-analysis-of-15%C3%A2-851-children-at-risk-of-inherited-metabolic-diseases
#12
Shu-Xiang Lin, Jian-Bo Shu, Chao Wang, Rui Pan, Ying-Tao Meng, Chun-Hua Zhang, Bi-Li Zhang, Dan Wang, Yu-Qin Zhang
OBJECTIVE: To explore the value of urine gas chromatography-mass spectrometry (GC-MS) in the screening of children at risk of inherited metabolic diseases (IMD), and to identify the disease spectrum of IMD and the clinical characteristics of children with IMD. METHODS: The clinical data of 15 851 children at risk of IMD who underwent urine GC-MS in the Tianjin Children's Hospital between February 2012 and December 2016 were retrospectively analyzed. RESULTS: In the 15 851 children, 5 793 (36...
December 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29236712/automatic-detection-and-decoding-of-honey-bee-waggle-dances
#13
Fernando Wario, Benjamin Wild, Raúl Rojas, Tim Landgraf
The waggle dance is one of the most popular examples of animal communication. Forager bees direct their nestmates to profitable resources via a complex motor display. Essentially, the dance encodes the polar coordinates to the resource in the field. Unemployed foragers follow the dancer's movements and then search for the advertised spots in the field. Throughout the last decades, biologists have employed different techniques to measure key characteristics of the waggle dance and decode the information it conveys...
2017: PloS One
https://www.readbyqxmd.com/read/29219092/systematic-review-of-the-relationships-between-sedentary-behaviour-and-health-indicators-in-the-early-years-0-4%C3%A2-years
#14
Veronica J Poitras, Casey E Gray, Xanne Janssen, Salome Aubert, Valerie Carson, Guy Faulkner, Gary S Goldfield, John J Reilly, Margaret Sampson, Mark S Tremblay
BACKGROUND: The purpose of this systematic review was to examine the relationships between sedentary behaviour (SB) and health indicators in children aged 0 to 4 years, and to determine what doses of SB (i.e., duration, patterns [frequency, interruptions], and type) were associated with health indicators. METHODS: Online databases were searched for peer-reviewed studies that met the a priori inclusion criteria: population (apparently healthy, 1 month to 4.99 years), intervention/exposure and comparator (durations, patterns, and types of SB), and outcome/health indicator (critical: adiposity, motor development, psychosocial health, cognitive development; important: bone and skeletal health, cardiometabolic health, fitness, risks/harm)...
November 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29219078/systematic-review-of-the-relationships-between-sleep-duration-and-health-indicators-in-the-early-years-0-4%C3%A2-years
#15
Jean-Philippe Chaput, Casey E Gray, Veronica J Poitras, Valerie Carson, Reut Gruber, Catherine S Birken, Joanna E MacLean, Salomé Aubert, Margaret Sampson, Mark S Tremblay
BACKGROUND: The objective of this systematic review was to examine for the first time the associations between sleep duration and a broad range of health indicators in children aged 0 to 4 years. METHODS: Electronic databases were searched with no limits on date or study design. Included studies (published in English or French) were peer-reviewed and met the a priori determined population (apparently healthy children aged 1 month to 4.99 years), intervention/exposure/comparator (various sleep durations), and outcome criteria (adiposity, emotional regulation, cognitive development, motor development, growth, cardiometabolic health, sedentary behaviour, physical activity, quality of life/well-being, and risks/injuries)...
November 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29209177/a-new-behavioral-test-and-associated-genetic-tools-highlight-the-function-of-ventral-abdominal-muscles-in-adult-drosophila
#16
Marine Pons, Claire Soulard, Laurent Soustelle, Marie-Laure Parmentier, Yves Grau, Sophie Layalle
The function of the nervous system in complex animals is reflected by the achievement of specific behaviors. For years in Drosophila, both simple and complex behaviors have been studied and their genetic bases have emerged. The neuromuscular junction is maybe one of the prototypal simplest examples. A motor neuron establishes synaptic connections on its muscle cell target and elicits behavior: the muscle contraction. Different muscles in adult fly are related to specific behaviors. For example, the thoracic muscles are associated with flight and the leg muscles are associated with locomotion...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29201862/the-influence-of-different-caregivers-on-infant-growth-and-development-in-china
#17
Qinrui Li, Furong Liang, Weilan Liang, Jing Zhang, Manman Niu, Ying Han
Objective: An increasing number of parents in China ask grandparents or babysitters to care for their children. Modern parents are often the only child in their family because of China's One-Child Policy and thus may lack interaction with siblings. Accordingly, the present study aimed to explore whether different caregivers affect the physical and development of infants in China. Methods: In total, 2,514 infants were enrolled in our study. We assessed their weight-for-age, supine length-for-age, weight-for-length, occipital-frontal circumference, and Denver Developmental Screening Test (DDST) results and recorded their general parental information and their primary caregivers...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29186725/-screening-of-executive-functions-in-patients-with-parkinson-s-disease-using-the-new-rapid-test-pal-5
#18
Jannik Florian Scheffels, Jasmin Elaine Engels, Elke Kalbe, Josef Kessler
Parkinson's disease (PD) is the second most prevalent chronic neurodegenerative disorder worldwide, following Alzheimer's disease. Along with the characteristic motor symptoms of the disorder, especially bradykinesia, cognitive deficits can often be found prior to the onset of the disorder. These mainly concern executive functioning. To detect cognitive deficits at an early stage, initial screening procedures are recommended. The new cognitive rapid test Paarassoziationslernen-5 ("PAL-5") has been developed to detect the most prevalent cognitive symptoms - namely executive impairments - of PD patients...
November 29, 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29181255/development-of-a-screening-protocol-to-identify-individuals-with-dysfunctional-breathing
#19
Kyle Kiesel, Tonya Rhodes, Jacob Mueller, Alyssa Waninger, Robert Butler
Introduction: Dysfunctional breathing (DB) has been linked to health conditions including low back pain and neck pain and adversely effects the musculoskeletal system. Individuals with DB often have decreased pain thresholds and impaired motor control, balance, and movement. No single test or screen identifies DB, which is multi-dimensional, and includes biochemical, biomechanical, and psychophysiological components. Several tools assess and test for DB, but no screen exists to determine whether additional testing and assessment are indicated...
October 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29170632/transcriptional-and-post-transcriptional-mechanisms-of-the-development-of-neocortical-lamination
#20
REVIEW
Tatiana Popovitchenko, Mladen-Roko Rasin
The neocortex is a laminated brain structure that is the seat of higher cognitive capacity and responses, long-term memory, sensory and emotional functions, and voluntary motor behavior. Proper lamination requires that progenitor cells give rise to a neuron, that the immature neuron can migrate away from its mother cell and past other cells, and finally that the immature neuron can take its place and adopt a mature identity characterized by connectivity and gene expression; thus lamination proceeds through three steps: genesis, migration, and maturation...
2017: Frontiers in Neuroanatomy
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