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https://www.readbyqxmd.com/read/29599670/dermoscopic-assessment-of-skin-toxicities-in-patients-with-melanoma-during-treatment-with-vemurafenib
#1
Marcin Rajczykowski, Grazyna Kaminska-Winciorek, Elzbieta Nowara, Marzenna Samborska-Plewicka, Sebastian Giebel
Introduction: The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities. Aim: To assess skin toxicities by dermoscopy in patients treated with vemurafenib. Material and methods: Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. All skin lesions occurring during therapy were assessed clinically and dermoscopically using a hand-held dermoscope with polarised and non-polarised light...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29558358/-gout-or-squamous-cell-cancer-of-the-ear-in-a-91-year-old-man-diagnostic-and-therapeutic-problems-a-case-report
#2
Andrzej N Majda, Aleksandra Majdan, Paweł Piłat, Paweł Cisek
Gout tophi around auricular area are common in old men. The differential diagnosis of papules or nodules on the ear includes tophaceous gout, rheumatoid nodules, basal or squamous cell cancer, melanoma, verruca vulgaris or actinic keratosis. The presence of the skin cancer, most commonly located on the head and neck, is often related to the long exposure of the skin to sunlight. Elderly patients are the predominant group of patients with skin malignancies. The aim of this study is to emphasize the importance of early cancer detection in elderly people and use of appropriate therapeutic options that take into account the special requirements of geriatric patients...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29515933/laryngeal-verruca-vulgaris-presenting-with-dysphonia-a-case-report
#3
Sibel Yıldırım, Zahide Çiler Tezcaner, Tural Fatullayev, Gürsel Dursun
Verruca vulgaris is a common skin lesion that is associated with human papilloma virus and is observed on the surface of skin. Verruca vulgaris is rarely seen in mucosal membranes. Atypical locations may be confused with verrucous carcinoma. The incidence of laryngeal verruca vulgaris has not yet been reported in the literature. Differential diagnoses in histopathological examinations include keratosis, squamous papilloma, verrucous hyperplasia, and verrucous carcinoma. Distinguishing disease from verrucous carcinoma is particularly important because the treatment approach can be altered...
December 2017: Turkish Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29513235/use-of-trichloroacetic-acid-for-management-of-oral-lesions-caused-by-human-papillomavirus
#4
Martha Carmona Lorduy, Jonathan Harris Ricardo, Yurtiza Hernández Arenas, Wanda Medina Carmona
The human papillomavirus (HPV) has an affinity for squamous cells of stratified keratinized epithelium, thus affecting the lower genital, nasal, and oral tracts. In the oral cavity, HPV is associated with pathoses such as the verruca vulgaris (common wart), squamous cell papilloma, condyloma acuminatum (venereal wart), and focal epithelial hyperplasia (Heck disease). Among the treatments available for these lesions are cryotherapy, electrosurgery, surgical removal, laser therapy, and trichloroacetic acid (TCA)...
March 2018: General Dentistry
https://www.readbyqxmd.com/read/29491614/cutaneous-horn-a-mask-to-underlying-malignancy
#5
Rashmi Gs Phulari, Rajendrasinh Rathore, Trupti Pramod Talegaon, Arpan Shah
Cutaneous horns ( cornu cutaneum ) are uncommon lesions consisting of keratotic material resembling that of an animal horn. It is a conical- or cylindrical-shaped excessive hyperkeratosis of variable size ranging from few millimeters to several centimeters with a variable in size and shape, such as cylindrical, conical, pointed, transversely or longitudinally corrugated, or curved like a ram's horn. The lesions typically occur in sun-exposed areas, particularly the face, ear, nose, forearms and dorsum of hands...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29483981/subungual-exostosis-in-a-young-soccer-player
#6
Georgi Tchernev, Yavor Grigorov, Stanislav Philipov, Anastasiya Chokoeva, Uwe Wollina, Torello Lotti, Jose Cardoso, Irina Yungareva, Ilia Lozev, Georgi Konstantinov Maximov
BACKGROUND: Subungual exostosis is a relatively uncommon, benign osteocartilaginous tumor of the distal phalanx of the toes or fingers in young adults, considered as a rare variant of osteochondroma. Differential diagnoses include subungual verruca (viral wart), pyogenic granuloma, osteochondroma, amelanotic subungual melanoma and glomus tumour. Misdiagnosis and total onychodystrophy frequently occur as a result of late treatment or inadequate treatment strategy. Dermoscopy could be a useful technique, involved in the diagnostic process, although X-ray examination and histopathology are mandatory for the diagnosis...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29447677/an-open-label-exploratory-study-evaluating-the-efficacy-and-safety-of-ingenol-mebutate-gel-0-05-for-the-treatment-of-verruca-vulgaris
#7
Neal D Bhatia
No abstract text is available yet for this article.
March 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29419892/autosomal-recessive-hyper-ige-syndrome-in-two-brothers-of-a-chinese-family-with-a-novel-mutation-in-dock8-gene
#8
Shan Wang, Wenjun Mou, Zhe Xu, Jingang Gui, Lin Ma
The hyper-IgE syndromes (HIES) are complex primary immunodeficiency disorders, including autosomal dominant form (AD-HIES) and recessive form (AR-HIES). Here we describe two boys with AR-HIES in a Chinese family and a novel mutation of DOCK8 gene was identified.The index patient was an 8-year-old boy. He presented with recurrent flexural skin lesions (similar with atopic dermatitis (AD)) for more than 5 years (Fig. 1a,b), and a 6-months history of severe molluscum contagiosum(Fig. 1c) and verruca plana(Fig...
February 8, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29418015/inverted-follicular-keratoses-of-the-buttocks
#9
Marie Kenney, Elizabeth B Lester, Deborah L Cook
No abstract text is available yet for this article.
February 8, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29414736/a-novel-cosmetic-and-clinically-practicable-laser-immunotherapy-for-facial-verruca-plana-intense-pulsed-light-combined-with-bcg-psn
#10
Fuhe Zhang, Lei Shi, Pei Liu, Linglin Zhang, Qianqian Wu, Bo Wang, Guolong Zhang, Peiru Wang, Feifang Zhou, Wei R Chen, Xiuli Wang
BACKGROUND: There is no alternative method to remove facial verruca plana and achieve better cosmetic effects. The present study is the first study to use intense pulsed light (IPL) as photothermal therapy (PTT) combined with intra-gluteal injection of bacillus calmette-guerin polysaccharide nucleic acid (BCG-PSN), which function as immunotherapy, contracting a new type of clinically available laser immunotherapy(LIT)for the treatment of facial verruca plana. The aim of this study was to evaluate the efficacy, cosmetic outcome, and adverse reactions of IPL combined with BCG-PSN for facial verruca plana...
February 4, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29379975/plantar-warts-epidemiology-pathophysiology-and-clinical-management
#11
Dexter Jordan Witchey, Nichole Brianne Witchey, Michele Marie Roth-Kauffman, Mark Kevin Kauffman
Verrucae plantaris (plantar warts) are common cutaneous lesions of the plantar aspect of the foot that are caused by the human papillomavirus (HPV). Ubiquitous in our environment, asymptomatic infection with HPV occurs frequently, with most infections controlled or cleared by cellular and humoral immune responses. However, certain populations have been observed to manifest plantar warts at higher rates compared with the general population, placing them at increased risk for wart-induced pain and complications...
February 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29373061/cirripede-cypris-antennules-how-much-structural-variation-exists-among-balanomorphan-species-from-hard-bottom-habitats
#12
Benny K K Chan, Alireza Sari, Jens T Høeg
Barnacle cypris antennules are important for substratum attachment during settlement and on through metamorphosis from the larval stage to sessile adult. Studies on the morphology of cirripede cyprids are mostly qualitative, based on descriptions from images obtained using a scanning electron microscope (SEM). To our knowledge, our study is the first to use scanning electron microscopy to quantify overall structural diversity in cypris antennules by measuring 26 morphological parameters, including the structure of sensory organs...
October 2017: Biological Bulletin
https://www.readbyqxmd.com/read/29250927/possible-role-of-interleukin-17-and-macrophage-migration-inhibitory-factor-in-cutaneous-warts
#13
Mohammed Abu El-Hamd, Hanan A Assaf, Essam A Nada
BACKGROUND/OBJECTIVES: Cutaneous warts (CW), or verrucae, are benign proliferation of skin that result from infection with human papilloma viruses. Cellular immune reactivity plays a significant role in wart regression. The aim of this study was to elucidate the cellular immune status of patients with CW through measurements of their serum levels of interleukin-17 (IL-17) and macrophage migration inhibitory factor (MIF,) and, identify the possible role of IL-17 and MIF in CW. We assessed serum IL-17 and MIF levels in patients with different forms of CW and compare the results with controls...
December 18, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29218494/efficacy-of-pulsed-dye-laser-treatment-for-common-warts-is-not-influenced-by-the-causative-hpv-type-a-prospective-study
#14
Yoseph Fichman, Assi Levi, Emmilia Hodak, Shlomit Halachmi, Sigal Mazor, Dana Wolf, Orit Caplan, Moshe Lapidoth
Verruca vulgaris (VV) is a prevalent skin condition caused by various subtypes of human papilloma virus (HPV). The most common causes of non-genital lesions are HPV types 2 and 4, and to a lesser extent types 1, 3, 26, 29, and 57. Although numerous therapeutic modalities exist, none is universally effective or without adverse events (AE). Pulsed dye laser (PDL) is a favorable option due to its observed efficacy and relatively low AE rate. However, it is not known which verrucae are most likely to respond to PDL, or whether the causative viral subtype influences this response...
December 7, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29151630/-juglanconis-gen-nov-on-juglandaceae-and-the-new-family-juglanconidaceae-diaporthales
#15
H Voglmayr, L A Castlebury, W M Jaklitsch
Molecular phylogenetic analyses of ITS-LSU rDNA sequence data demonstrate that Melanconis species occurring on Juglandaceae are phylogenetically distinct from Melanconis s.str., and therefore the new genus Juglanconis is described. Morphologically, the genus Juglanconis differs from Melanconis by light to dark brown conidia with irregular verrucae on the inner surface of the conidial wall, while in Melanconis s.str. they are smooth. Juglanconis forms a separate clade not affiliated with a described family of Diaporthales , and the family Juglanconidaceae is introduced to accommodate it...
June 2017: Persoonia
https://www.readbyqxmd.com/read/28979663/finger-pad-squamous-cell-carcinoma-report-of-squamous-cell-carcinoma-of-the-distal-palmar-digit-and-review-of-associated-risk-factors-mimickers-and-treatment-of-squamous-cell-carcinoma-of-ventral-hand-digits
#16
Philip R Cohen, S Brian Jiang
BACKGROUND: Squamous cell carcinoma of the palmar digits is rare. PURPOSE: The authors describe a man with squamous cell carcinoma of the pulp of his left fourth finger, and review the risk factors that may be associated with squamous cell carcinoma development on the ventral digits of the hand. the authors also summarize the clinical differential diagnoses and treatment of squamous cell carcinoma at this location. METHODS: the authors retrospectively reviewed the literature using PubMed and searched for the following terms: squamous cell carcinoma, squamous cell carcinoma in situ, finger, thumb, palmar, and ventral...
August 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28979029/lower-extremity-desmoplastic-malignant-melanoma-in-egypt
#17
Reham William Doss, Sahar Daoud, Alshimaa Mohamed Abbas Mostafa, Sara Abd Elrahman Mohammed
Desmoplastic melanoma (DM) is a type of spindle cell melanoma characterized by the absence of pigment. The clinical diagnosis of DM represents a challenge for the practitioner and the pathologists because it can mimic benign or malignant skin tumors and even inflammatory skin disorders. We here discuss a case of a patient presented with multiple nodular lesions of the lower extremity following electrocautary to a lesion in her sole which was misdiagnosed as planter wart. Our clinical diagnosis was Kaposi sarcoma, hypertrophic lichen, or extensive verruca vulgaris...
September 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28932954/-verrucae-hyperpigmentation-palmar-hyperkeratosis
#18
E Sody, W Sondermann, A Körber
No abstract text is available yet for this article.
September 20, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28871926/translation-and-validation-of-the-serbian-version-of-the-skindex-29-instrument-for-measuring-impact-of-skin-disease-on-quality-of-life
#19
Jelena D Milutinović, Nebojša Krstić, Slobodan M Janković
The Skindex-29 instrument, which is intended for measuring the influence of skin diseases on quality of life, was developed and validated in several languages. However, a Serbian translation of the instrument is not available. The aim of this study was to translate the Skindex-29 from English to Serbian, to make necessary cultural adaptations, and to test its psychometric properties in a sample of outpatients with various skin diseases. The Skindex-29 was translated and adapted according to internationally accepted guidelines and then tested on a sample of Serbian outpatients with various skin diseases...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28852295/safety-and-efficacy-of-intralesional-vitamin-d3-in-cutaneous-warts-an-open-uncontrolled-trial
#20
Manjunath Kavya, Basavapura Madegowda Shashikumar, Muddanahalli Rajegowda Harish, Bhadbhade P Shweta
BACKGROUND: Cutaneous warts are treated primarily with destructive methods such as cryotherapy or electrocautery. These modalities of treatment are time-consuming and may be associated with scarring in multiple warts. Immunotherapy is emerging as a new modality of treatment which acts on enhancing cell-mediated immunity against human papillomavirus for clearance of both treated and distant warts. AIMS: This study aims to evaluate the safety and efficacy of intralesional Vitamin D3 for the treatment of cutaneous warts...
April 2017: Journal of Cutaneous and Aesthetic Surgery
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