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https://www.readbyqxmd.com/read/28209836/draft-genome-sequence-of-a-vibrio-harveyi-strain-associated-with-vibriosis-in-pacific-white-shrimp-litopenaeus-vannamei
#1
Emille Moreno, Marci Parks, Lee J Pinnell, James J Tallman, Jeffrey W Turner
Vibrio harveyi is a Gram-negative bacterium associated with vibriosis in penaeid shrimp. Here, we report the draft genome sequence of a V. harveyi strain isolated from Pacific white shrimp (Litopenaeus vannamei) during a vibriosis outbreak. The availability of this genome will aid future studies of vibriosis in shrimp aquaculture.
February 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28209167/erratum-to-the-effectiveness-of-the-peer-delivered-thinking-healthy-plus-thpp-programme-for-maternal-depression-and-child-socio-emotional-development-in-pakistan-study-protocol-for-a-three-year-cluster-randomized-controlled-trial
#2
Elizabeth L Turner, Siham Sikander, Omer Bangash, Ahmed Zaidi, Lisa Bates, John Gallis, Nima Ganga, Karen O'Donnell, Atif Rahman, Joanna Maselko
No abstract text is available yet for this article.
February 16, 2017: Trials
https://www.readbyqxmd.com/read/28208039/understanding-the-language-of-intensive-care-physicians
#3
Richard C Turner
No abstract text is available yet for this article.
February 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28207940/structural-and-functional-changes-to-lymph-nodes-in-ageing-mice
#4
Vivian M Turner, Neil A Mabbott
Lymph nodes (LN) are secondary lymphoid organs spread throughout the lymphatic system. They function to filter pathogenic material from the lymphatic fluid to maintain the health of the organism. Subcapsular sinus macrophages (SCSM) are amongst the first-responders within the LN due to their strategic location within the subcapsular sinus region. These macrophages aid the delivery of immune complexes to B cells and follicular dendritic cells (FDC) within the LN. Here we show an increase in SCSM and other macrophage populations within aged LN...
February 16, 2017: Immunology
https://www.readbyqxmd.com/read/28207864/characterisation-and-genome-sequence-of-the-lytic-acinetobacter-baumannii-bacteriophage-vb_abas_loki
#5
Dann Turner, Matthew E Wand, Yves Briers, Rob Lavigne, J Mark Sutton, Darren M Reynolds
Acinetobacter baumannii has emerged as an important nosocomial pathogen in healthcare and community settings. While over 100 of Acinetobacter phages have been described in the literature, relatively few have been sequenced. This work describes the characterisation and genome annotation of a new lytic Acinetobacter siphovirus, vB_AbaS_Loki, isolated from activated sewage sludge. Sequencing revealed that Loki encapsulates a 41,308 bp genome, encoding 51 predicted open reading frames. Loki is most closely related to Acinetobacter phage IME_AB3 and more distantly related to Burkholderia phage KL1, Paracoccus phage vB_PmaS_IMEP1 and Pseudomonas phages vB_Pae_Kakheti25, vB_PaeS_SCH_Ab26 and PA73...
2017: PloS One
https://www.readbyqxmd.com/read/28207813/interacting-networks-of-resistance-virulence-and-core-machinery-genes-identified-by-genome-wide-epistasis-analysis
#6
Marcin J Skwark, Nicholas J Croucher, Santeri Puranen, Claire Chewapreecha, Maiju Pesonen, Ying Ying Xu, Paul Turner, Simon R Harris, Stephen B Beres, James M Musser, Julian Parkhill, Stephen D Bentley, Erik Aurell, Jukka Corander
Recent advances in the scale and diversity of population genomic datasets for bacteria now provide the potential for genome-wide patterns of co-evolution to be studied at the resolution of individual bases. Here we describe a new statistical method, genomeDCA, which uses recent advances in computational structural biology to identify the polymorphic loci under the strongest co-evolutionary pressures. We apply genomeDCA to two large population data sets representing the major human pathogens Streptococcus pneumoniae (pneumococcus) and Streptococcus pyogenes (group A Streptococcus)...
February 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28207470/improving-functional-and-aesthetic-outcomes-in-syndromic-patients-with-webbed-neck-deformity-utilizing-a-staged-endoscopic-assisted-approach-to-improve-the-posterior-hairline-and-decrease-scar-burden
#7
Emily Van Kouwenberg, Anmol S Chattha, Oluwaseun A Adetayo
INTRODUCTION: Webbed neck deformity (WND) can have significant functional and psychosocial impact on the developing child. Surgical correction can be challenging depending on the extent of the deformity, and patients often also have low posterior hairlines requiring simultaneous correction. Current surgical techniques include various methods of single-stage radical excision that often result in visible scar burden and residual deformity. There is currently no general consensus of which technique provides the best outcomes...
February 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28205604/selectively-bred-rats-provide-a-unique-model-of-vulnerability-to-ptsd-like-behavior-and-respond-differentially-to-fgf2-augmentation-early-in-life
#8
Katherine E Prater, Elyse L Aurbach, Hanna K Larcinese, Taylor N Smith, Cortney A Turner, Peter Blandino, Stanley J Watson, Stephen Maren, Huda Akil
Individuals respond differently to traumatic experiences including their propensity to develop post-traumatic stress disorder (PTSD). Understanding individual differences in PTSD vulnerability will allow the development of improved prevention and treatment options. Here, we characterized fear conditioning and extinction in rats selectively bred for differences in their locomotor response to a novel environment. Selectively bred high responder (bHR) and low responder (bLR) male rats are known to differ in their emotional reactivity on a range of measures of spontaneous anxiety- and depressive-like behaviors...
February 16, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28205498/cognitive-control-learning-and-clinical-motor-ratings-are-most-highly-associated-with-basal-ganglia-brain-volumes-in-the-premanifest-huntington-s-disease-phenotype
#9
Maria B Misiura, Spencer Lourens, Vince D Calhoun, Jeffrey Long, Jeremy Bockholt, Hans Johnson, Ying Zhang, Jane S Paulsen, Jessica A Turner, Jingyu Liu, Betul Kara, Elizabeth Fall
OBJECTIVES: Huntington's disease (HD) is a debilitating genetic disorder characterized by motor, cognitive and psychiatric abnormalities associated with neuropathological decline. HD pathology is the result of an extended chain of CAG (cytosine, adenine, guanine) trinucleotide repetitions in the HTT gene. Clinical diagnosis of HD requires the presence of an otherwise unexplained extrapyramidal movement disorder in a participant at risk for HD. Over the past 15 years, evidence has shown that cognitive, psychiatric, and subtle motor dysfunction is evident decades before traditional motor diagnosis...
February 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28205448/association-between-red-meat-consumption-and-colon-cancer-a-systematic-review-of-experimental-results
#10
Nancy D Turner, Shannon K Lloyd
A role for red and processed meat in the development of colorectal cancer has been proposed based largely on evidence from observational studies in humans, especially in those populations consuming a westernized diet. Determination of causation specifically by red or processed meat is contingent upon identification of plausible mechanisms that lead to colorectal cancer. We conducted a systematic review of the available evidence to determine the availability of plausible mechanistic data linking red and processed meat consumption to colorectal cancer risk...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28202807/the-genetics-of-mate-preferences-in-hybrids-between-two-young-and-sympatric-lake-victoria-cichlid-species
#11
Ola Svensson, Katie Woodhouse, Cock van Oosterhout, Alan Smith, George F Turner, Ole Seehausen
The genetic architecture of mate preferences is likely to affect significant evolutionary processes, including speciation and hybridization. Here, we investigate laboratory hybrids between a pair of sympatric Lake Victoria cichlid fish species that appear to have recently evolved from a hybrid population between similar predecessor species. The species demonstrate strong assortative mating in the laboratory, associated with divergent male breeding coloration (red dorsum versus blue). We show in a common garden experiment, using DNA-based paternity testing, that the strong female mate preferences among males of the two species are fully recovered in a large fraction of their F2 hybrid generation...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28202365/optimising-the-use-of-medicines-to-reduce-acute-kidney-injury-in-children-and-babies
#12
REVIEW
L Oni, D B Hawcutt, M A Turner, M W Beresford, S McWilliam, C Barton, B K Park, P Murray, B Wilm, I Copple, R Floyd, M Peak, A Sharma, D J Antoine
The majority of medications in children are administered in an unlicensed or off-label manner. Paediatricians are obliged to prescribe using the limited evidence available. The 2007 EU regulation on the use of paediatric drugs means pharmaceutical companies are now obliged to (and receive incentives for) contributing to paediatric drug data and carrying out paediatric clinical trials. This is important, as the efficacy and adverse effect profiles of medicines vary across childhood. Additionally, there are significant age-related changes in the pharmacodynamic and pharmacokinetic activity of many drugs...
February 12, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28202295/feasibility-of-upright-patient-positioning-and-intubation-success-rates-at-two-academic-emergency-departments
#13
Joseph S Turner, Timothy J Ellender, Enola R Okonkwo, Tyler M Stepsis, Andrew C Stevens, Erik G Sembroski, Christopher S Eddy, Anthony J Perkins, Dylan D Cooper
OBJECTIVES: Endotracheal intubation is most commonly taught and performed in the supine position. Recent literature suggests that elevating the patient's head to a more upright position may decrease peri-intubation complications. However, there is little data on the feasibility of upright intubation in the emergency department. The goal of this study was to measure the success rate of emergency medicine residents performing intubation in supine and non-supine, including upright positions...
February 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28202274/marine-debris-in-five-national-parks-in-alaska
#14
L Polasek, J Bering, H Kim, P Neitlich, B Pister, M Terwilliger, K Nicolato, C Turner, T Jones
Marine debris is a management issue with ecological and recreational impacts for agencies, especially on remote beaches not accessible by road. This project was implemented to remove and document marine debris from five coastal National Park Service units in Alaska. Approximately 80km of coastline were cleaned with over 10,000kg of debris collected. Marine debris was found at all 28 beaches surveyed. Hard plastics were found on every beach and foam was found at every beach except one. Rope/netting was the next most commonly found category, present at 23 beaches...
February 12, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28202269/trace-elements-in-fragments-of-fishing-net-and-other-filamentous-plastic-litter-from-two-beaches-in-sw-england
#15
Andrew Turner
Filamentous plastic litter collected from two beaches in south west England has been characterized by FTIR and XRF. The majority of samples were constructed of polyethylene and consisted of twisted or braided strands of a variety of colours that appeared to be derived from commercial fishing nets. A number of different elements were detected among the samples but, from an environmental perspective, the regular occurrence of Cr and Pb and the occasional or isolated occurrence of Br, Cd and Se were of greatest concern...
February 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28202212/long-term-patient-reported-urinary-function-following-external-beam-radiotherapy-for-prostate-cancer
#16
S Chin, A J Hayden, V Gebski, S Cross, S L Turner
INTRODUCTION: This study reports long-term patient reported urinary function and urinary-related quality of life (uQoL) after external beam radiotherapy (EBRT) for localized prostate cancer. METHODS: 574 men underwent definitive prostate EBRT to 70-78 Gy±androgen deprivation therapy between 2000 and 2009. The median follow-up from EBRT was 44 months. Patients were evaluated at baseline (pre-EBRT) and at intervals post-treatment using the International Prostate Symptom Score (IPSS) instrument...
February 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28202037/tailored-multifactorial-intervention-to-improve-dizziness-symptoms-and-quality-of-life-balance-and-gait-in-dizziness-sufferers-aged-over-50%C3%A2-years-protocol-for-a-randomised-controlled-trial
#17
Jasmine C Menant, Americo A Migliaccio, Cameron Hicks, Joanne Lo, Daniela Meinrath, Mayna Ratanapongleka, Jessica Turner, Daina L Sturnieks, Kim Delbaere, Nickolai Titov, Catherine McVeigh, Jacqueline C T Close, Stephen R Lord
BACKGROUND: Dizziness is a frequently reported symptom in older people that can markedly impair quality of life. This manuscript presents the protocol for a randomised controlled trial, which has the main objective of determining the impact of comprehensive assessment followed by a tailored multifaceted intervention in reducing dizziness episodes and symptoms, improving associated impairments to balance and gait and enhancing quality of life in older people with self-reported significant dizziness...
February 15, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28199910/subthreshold-body-dysmorphic-disorder-in-adolescents-prevalence-and-impact
#18
Sophie C Schneider, Jonathan Mond, Cynthia M Turner, Jennifer L Hudson
The aim of the current study was to establish the prevalence of subthreshold body dysmorphic disorder (subthreshold-BDD) in a community sample of adolescents, and to compare disorder correlates in individuals with subthreshold-BDD to those with probable full-syndrome BDD (probable-BDD) and those without BDD (non-BDD). Self-report questionnaires assessing DSM-IV BDD criteria, past mental health service use, and symptoms of body dysmorphic disorder, anxiety, depression, obsessive-compulsive disorder and eating disorders, were completed by 3149 Australian high school students (mean age =14...
January 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28199784/allosensitization-following-bone-graft
#19
Eoin D O'Sullivan, Richard K Battle, Sharon Zahra, John F Keating, Lorna P Marson, David M Turner
It is recognised that patients may become sensitized to donor-specific HLA antigens as a result of previous antigenic exposures, classically through previous transplantation, pregnancy or blood transfusion. We present an unusual case of a patient who unexpectedly developed a range of anti-HLA antibodies following orthopaedic surgery where a bone graft was deployed intraoperatively. We describe the case of a 52-year-old male awaiting a renal transplantation, undergoing elective orthopaedic surgery requiring a small volume bone graft...
February 15, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28199392/comparison-of-the-population-excess-fraction-of-chlamydia-trachomatis-infection-on-pelvic-inflammatory-disease-at-12-months-in-the-presence-and-absence-of-chlamydia-testing-and-treatment-systematic-review-and-retrospective-cohort-analysis
#20
Bethan Davies, Katy M E Turner, Stella Leung, B Nancy Yu, Maria Frølund, Thomas Benfield, James Blanchard, Henrik Westh, Helen Ward
BACKGROUND: The impact of Chlamydia trachomatis (chlamydia) control on the incidence of pelvic inflammatory disease (PID) is theoretically limited by the proportion of PID caused by chlamydia. We estimate the population excess fraction (PEF) of treated chlamydia infection on PID at 12-months in settings with widespread chlamydia control (testing and treatment) and compare this to the estimated PEF of untreated chlamydia. METHODS: We used two large retrospective population-based cohorts of women of reproductive age from settings with widespread chlamydia control to calculate the PEF of treated chlamydia on PID at 12-months...
2017: PloS One
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