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https://www.readbyqxmd.com/read/27920812/evaluation-of-the-bone-mineral-density-of-the-subjects-with-avascular-necrosis-of-hip-joint
#1
Mohammad Taghi Karimi, Seyed Mohammad Mousavi Nodoshan
BACKGROUND: The head of femur is deformed in subjects with Leg Calve Perthes Disease (LCPD). It may be due to an increase in loads applied on the hip, decrease in hip joint containment and decrease in bone mineral density (BMD) of femur. Unfortunately there is not enough evidence regarding BMD of femur in subjects with LCPD. Therefore, the aim of this study is to evaluate BMD in subjects with Perthes disease. METHOD: Two subjects with LCPD participated in this study...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27904729/treatment-of-late-onset-legg-calve-perthes-disease-by-arthrodiastasis
#2
Sung Soo Kim, Chan Woo Lee, Hyeon Jun Kim, Hyun Ho Kim, Lih Wang
BACKGROUND: To evaluate the efficacy of arthrodiastasis for Legg-Calve-Perthes disease. METHODS: Arthrodiastasis was conducted using external fixator devices (Orthofix) in 7 patients at least 8 years of age with a diagnosis of Legg-Calve-Perthes disease. The average follow-up was 80 months (range, 32 to 149 months), and their average age was 9.1 years (range, 8 to 12 years). The results of treatment were evaluated by measuring the degree of hip pain and the range of motion of the hip at 6 months after the operation and comparing the values with preoperative measurements...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27902719/community-wide-distribution-of-a-catalytic-device-to-reduce-winter-ambient-fine-particulate-matter-from-residential-wood-combustion-a-field-study
#3
Olivia Johnston, Fay Johnston, John Todd, Grant Williamson
Residential wood combustion is the main source of elevated concentrations of fine particulate matter (PM2.5) during winter in many towns of Tasmania, Australia. A commercially available firebox catalyst in Australia has previously been shown to reduce visible smoke emissions and the manufacturer reports reductions in particle emissions generated from individual wood heaters in laboratory settings. This study aimed to evaluate the potential for community-wide distribution of the catalyst to improve the ambient winter air quality in the field...
2016: PloS One
https://www.readbyqxmd.com/read/27895402/effect-of-airplane-transport-of-donor-livers-on-post-liver-transplantation-survival
#4
Yi Huang, Gerry MacQuillan, Leon A Adams, George Garas, Megan Collins, Albert Nwaba, Linjun Mou, Max K Bulsara, Luc Delriviere, Gary P Jeffrey
AIM: To evaluate the effect of long haul airplane transport of donor livers on post-transplant outcomes. METHODS: A retrospective cohort study of patients who received a liver transplantation was performed in Perth, Australia from 1992 to 2012. Donor and recipient characteristics information were extracted from Western Australian liver transplantation service database. Patients were followed up for a mean of six years. Patient and graft survival were evaluated and compared between patients who received a local donor liver and those who received an airplane transported donor liver...
November 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27886352/alterations-of-serum-osteocalcin-levels-in-patients-with-legg-calv%C3%A3-perthes
#5
Wen-Bo Wei, Sha-Jie Dang, Yong Li, Zong-Zhi Liu
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is a paediatric form of osteonecrosis that ultimately heals but will cause femoral head and acetabular deformities. The purpose of this study was to investigate the early serum measurement of osteocalcin in children with femoral head necrosis compared with that of healthy children. METHODS: 20 patients with LCPD (4 girls and 16 boys) and 20 healthy volunteers (5 girls and 15 boys) were enrolled. All patients did not have additional treatment...
November 14, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27865764/phase-2a-randomized-clinical-trial-safety-and-post-hoc-analysis-of-subretinal-raav-sflt-1-for-wet-age-related-macular-degeneration
#6
Ian J Constable, Cora M Pierce, Chooi-May Lai, Aaron L Magno, Mariapia A Degli-Esposti, Martyn A French, Ian L McAllister, Steve Butler, Samuel B Barone, Steven D Schwartz, Mark S Blumenkranz, Elizabeth P Rakoczy
BACKGROUND: We present the results of a Phase 2a randomized controlled trial investigating the safety, and secondary endpoints of subretinal rAAV.sFLT-1 gene therapy in patients with active wet age-related macular degeneration (wAMD). METHODS: All patients (n=32), (ClinicalTrials.gov; NCT01494805), received ranibizumab injections at baseline and week 4, and thereafter according to prespecified criteria. Patients in the gene therapy group (n=21) received rAAV.sFLT-1 (1×10(11)vg)...
November 10, 2016: EBioMedicine
https://www.readbyqxmd.com/read/27864891/3d-mri-quantification-of-femoral-head-deformity-in-legg-calv%C3%A3-perthes-disease
#7
Karen D Standefer, Molly Dempsey, ChanHee Jo, Harry K W Kim
The purpose of this study was to quantify femoral head deformity in patients with Legg-Calvé-Perthes disease (LCPD) using a novel three dimensional (3D) magnetic resonance imaging (MRI) reconstruction and volume based analysis. Bilateral femoral heads of 17 patients (mean age 9.9 ± 2.0 years; 12 boys, 5 girls) with LCPD were scanned 1-2 times (n= 33 LCPD heads, 20 normal heads) using a 1.5T MRI scanner. Fourteen patients had unilateral and three had bilateral LCPD with 5 hips in the Waldenström initial stage, 9 in the fragmentation stage, 14 in the reossification stage, and 5 in the healed stage...
November 19, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27864251/post-hoc-evaluation-of-a-common-sense-intervention-for-asthma-management-in-community-pharmacy
#8
Kim Watkins, Liza Seubert, Carl R Schneider, Rhonda Clifford
OBJECTIVES: The aim was to evaluate a common-sense, behavioural change intervention to implement clinical guidelines for asthma management in the community pharmacy setting. DESIGN: The components of the common-sense intervention were described in terms of categories and dimensions using the Intervention Taxonomy (ITAX) and Behaviour Change Techniques (BCTs) using the Behaviour Change Wheel (BCW), Capability, Opportunity and Motivation-Behaviour (COM-B) System and Behaviour Change Techniques Taxonomy (BCTTv1)...
November 18, 2016: BMJ Open
https://www.readbyqxmd.com/read/27852919/can-we-solve-legg-calv%C3%A3-perthes-disease-with-better-imaging-technology-commentary-on-an-article-by-harry-k-w-kim-md-ms-et-al-assessment-of-femoral-head-revascularization-in-legg-calv%C3%A3-perthes-disease-using-serial-perfusion-mri
#9
https://www.readbyqxmd.com/read/27852906/assessment-of-femoral-head-revascularization-in-legg-calv%C3%A3-perthes-disease-using-serial-perfusion-mri
#10
Harry K W Kim, Jamie Burgess, Alec Thoveson, Paul Gudmundsson, Molly Dempsey, Chan-Hee Jo
BACKGROUND: Legg-Calvé-Perthes disease is a juvenile form of osteonecrosis of the femoral head. The purpose of this study was to use serial perfusion magnetic resonance imaging (MRI) to determine the pattern and rate of revascularization of the femoral heads of patients with the active stage of Legg-Calvé-Perthes disease. METHODS: We performed a prospective study of 29 patients (30 hips) with a mean age (and standard deviation) of 8.4 ± 1.9 years who were diagnosed with Waldenström Stage-1 or 2 Legg-Calvé-Perthes disease...
November 16, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27832014/proximal-femoral-osteotomy-in-legg-calv%C3%A3-perthes-disease-using-a-monolateral-external-fixator-surgical-technique-outcome-and-complications
#11
Kwang-Won Park, Ishani P Shah, Ashok K Ramanathan, Tae-Jin Lee, Hae-Ryong Song
: Although external fixation methods have been described for proximal femoral osteotomy for various etiologies, none are dedicated to a single disease entity. Our study introduces a technique of proximal femoral osteotomy and fixation with a monolateral external fixator system in Legg-Calvé-Perthes disease (LCPD). Twenty-three patients (19 males, four females) with LCPD underwent surgery at our institute between 2004 and 2012. Varus osteotomy (group A, 11 hips) and valgus osteotomy (group B, 12 hips) were performed and the monolateral external fixator system was used...
November 9, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27830486/three-patterns-of-acetabular-deficiency-are-common-in-young-adult-patients-with-acetabular-dysplasia
#12
Jeffrey J Nepple, Joel Wells, James R Ross, Asheesh Bedi, Perry L Schoenecker, John C Clohisy
BACKGROUND: Detailed recognition of the three-dimensional (3-D) deformity in acetabular dysplasia is important to help guide correction at the time of reorientation during periacetabular osteotomy (PAO). Common plain radiographic parameters of acetabular dysplasia are limited in their ability to characterize acetabular deficiency precisely. The 3-D characterization of such deficiencies with low-dose CT may allow for more precise characterization. QUESTIONS/PURPOSES: The purposes of this study were (1) to determine the variability in 3-D acetabular deficiency in acetabular dysplasia; (2) to define subtypes of acetabular dysplasia based on 3-D morphology; (3) to determine the correlation of plain radiographic parameters with 3-D morphology; and (4) to determine the association of acetabular dysplasia subtype with patient clinical characteristics including sex, range of motion, and femoral version...
November 9, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27829728/mr-arthrography-evaluation-in-patients-with-traumatic-anterior-shoulder-instability
#13
Luca Saba, Massimo De Filippo
INTRODUCTION: To evaluate retrospectively the diagnostic accuracy of MR arthrography, compared with arthroscopy, in research of the glenoid labrum tear in patients with a first episode of traumatic anterior shoulder instability (TUBS). MATERIAL AND METHODS: We retrospectively reviewed the MR arthrography shoulder images of 118 patients with a first episode of TUBS, between June 2014 and May 2016. RESULTS: The overall accuracy of MR arthrography compared with arthroscopy of the glenoid labrum lesions was 94%, sensitivity 93%, and specificity 96%...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27828982/discovery-and-partial-genomic-characterisation-of-a-novel-nidovirus-associated-with-respiratory-disease-in-wild-shingleback-lizards-tiliqua-rugosa
#14
Mark A O'Dea, Bethany Jackson, Carol Jackson, Pally Xavier, Kristin Warren
A respiratory disease syndrome has been observed in large numbers of wild shingleback lizards (Tiliqua rugosa) admitted to wildlife care facilities in the Perth metropolitan region of Western Australia. Mortality rates are reportedly high without supportive treatment and care. Here we used next generation sequencing techniques to screen affected and unaffected individuals admitted to Kanyana Wildlife Rehabilitation Centre in Perth between April and December 2015, with the resultant discovery of a novel nidovirus significantly associated with cases of respiratory disease according to a case definition based on clinical signs...
2016: PloS One
https://www.readbyqxmd.com/read/27828848/lateral-shelf-acetabuloplasty-for-severe-legg-calv%C3%A3-perthes-disease-in-patients-older-than-8-years-a-mean-eleven-year-follow-up
#15
Wen-Chao Li, Rui-Jiang Xu
The natural history of Legg-Calvé-Perthes disease (LCPD) in children older than 8 years is usually poor without treatment. The treatment goal is to prevent deformity and incongruity of the hip by achieving a stable spherical femoral head in a deep, congruent, sharp-edged acetabulum, with a good range of hip movement at skeletal maturity. Lateral shelf acetabuloplasty in LCPD can increase the coverage of the femoral head, benefiting the remodeling of the femoral head and acetabulum. The aim of this study was to evaluate the efficacy of lateral shelf acetabuloplasty for severe LCPD in patients older than 8 years...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27826701/a-cadaver-study-validating-ct-assessment-of-acetabular-component-orientation-the-perth-ct-hip-protocol
#16
Varun Arora, Richard Hannan, Richard Beaver, Timothy Fletcher, Paul Harvie
OBJECTIVE: The aim was to develop a CT-based protocol to accurately measure post-operative acetabular cup inclination and anteversion establishing which bony reference points facilitate the most accurate estimation of these variables. MATERIALS AND METHODS: An all-polyethylene acetabular liner was implanted into a cadaveric acetabulum. A conventional pelvic CT scan was performed and reformatted images created in both functional and anterior pelvic planes. CT images were transferred to a Freedom-Plus Graphics software package enabling an identical, virtual 3D model of the cadaveric pelvis to be created and definitive acetabular cup orientation established...
November 8, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27824790/intermediate-to-long-term-results-of-femoral-neck-lengthening-morscher-osteotomy
#17
Mark Eidelman, Doron Keshet, Scott Nelson, Noam Bor
BACKGROUND: Femoral neck lengthening and transfer of the greater trochanter were introduced by Morscher as treatment for patients with coxa breva and overgrowth of the greater trochanter. In this study we evaluated intermediate and long-term results of this operation. METHODS: We reviewed clinical and radiographic results of 18 patients (20 hips) who were treated by Morscher osteotomy. Ten patients had Perthes disease, 4 had developmental dysplasia of the hip, and 4 had avascular necrosis of the hip...
November 7, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27821195/characterizing-the-risk-of-respiratory-syncytial-virus-in-infants-with-older-siblings-a-population-based-birth-cohort-study
#18
P Jacoby, K Glass, H C Moore
From a population-based birth cohort of 245 249 children born in Western Australia during 1996-2005, we used linkage of laboratory and birth record datasets to obtain data including all respiratory syncytial virus (RSV) detections during infancy from a subcohort of 87 981 singleton children born in the Perth metropolitan area from 2000 to 2004. Using log binomial regression, we found that the risk of infant RSV detection increases with the number of older siblings, with those having ⩾3 older siblings experiencing almost three times the risk (relative risk 2·83, 95% confidence interval 2·46-3·26) of firstborn children...
November 8, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27812415/human-altruistic-tendencies-vary-with-both-the-costliness-of-selfless-acts-and-socioeconomic-status
#19
Cyril C Grueter, Jesse A Ingram, James W Lewisson, Olivia R Bradford, Melody Taba, Rebecca E Coetzee, Michelle A Sherwood
Altruism toward strangers is considered a defining feature of humans. However, manifestation of this behaviour is contingent on the costliness of the selfless act. The extent of altruistic tendencies also varies cross-culturally, being more common in societies with higher levels of market integration. However, the existence of local variation in selfless behaviour within populations has received relatively little empirical attention. Using a 'lost letter' design, we dropped 300 letters (half of them stamped, half of them unstamped) in 15 residential suburbs of the greater Perth area that differ markedly in socioeconomic status...
2016: PeerJ
https://www.readbyqxmd.com/read/27794284/evening-choruses-in-the-perth-canyon-and-their-potential-link-with-myctophidae-fishes
#20
Robert D McCauley, Douglas H Cato
An evening chorus centered at near 2.2 kHz was detected across the years 2000 to 2014 from seabed receivers in 430-490 m depth overlooking the Perth Canyon, Western Australia. The chorus reached a maximum level typically 2.1 h post-sunset and normally ran for 2.1 h (between 3 dB down points). It was present at lower levels across most of the hours of darkness. Maximum chorus spectrum levels were 74-76 dB re 1 μPa(2)/Hz in the 2 kHz 1/3 octave band, averaging 6-12 dB and up to 30 dB greater than pre-sunset levels...
October 2016: Journal of the Acoustical Society of America
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