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https://www.readbyqxmd.com/read/27916911/a-multipurpose-cmos-platform-for-nanosensing
#1
Alberto Bonanno, Alessandro Sanginario, Simone L Marasso, Beatrice Miccoli, Katarzyna Bejtka, Simone Benetto, Danilo Demarchi
This paper presents a customizable sensing system based on functionalized nanowires (NWs) assembled onto complementary metal oxide semiconductor (CMOS) technology. The Micro-for-Nano (M4N) chip integrates on top of the electronics an array of aluminum microelectrodes covered with gold by means of a customized electroless plating process. The NW assembly process is driven by an array of on-chip dielectrophoresis (DEP) generators, enabling a custom layout of different nanosensors on the same microelectrode array...
November 30, 2016: Sensors
https://www.readbyqxmd.com/read/27914431/complex-modes-expansion-with-vector-projection-using-power-flow-to-simulate-lamb-waves-scattering-from-horizontal-cracks-and-disbonds
#2
Banibrata Poddar, Victor Giurgiutiu
This paper presents an inexpensive but accurate analytical method to calculate the scattering of straight-crested Lamb waves from cracks parallel to the plate surface. The same method is applicable for the disbond problem. In this method, the scatter field is expanded in terms of complex Lamb wave modes with unknown amplitudes. These unknown amplitudes are obtained from the boundary conditions using vector projection utilizing the power expression. The process works by projecting the stress conditions onto the displacement eigen-spaces of complex Lamb wave modes and vice versa...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27910669/end-loss-analyzer-system-for-measurements-of-plasma-flux-at-the-c-2u-divertor-electrode
#3
M E Griswold, S Korepanov, M C Thompson
An end loss analyzer system consisting of electrostatic, gridded retarding-potential analyzers and pyroelectric crystal bolometers was developed to characterize the plasma loss along open field lines to the divertors of C-2U. The system measures the current and energy distribution of escaping ions as well as the total power flux to enable calculation of the energy lost per escaping electron/ion pair. Special care was taken in the construction of the analyzer elements so that they can be directly mounted to the divertor electrode...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910381/single-phase-driven-ultrasonic-motor-using-two-orthogonal-bending-modes-of-sandwiching-piezo-ceramic-plates
#4
Yuting Ma, Minkyu Choi, Kenji Uchino
A compact ultrasonic motor using sandwiching piezo-ceramic plates was developed, having advantages of low manufacturing costs, simple driving circuit, and high scalability. The stator is composed of two piezoelectric plates attached to a T-shaped steel body. Two orthogonal bending modes can be excited by driving one piezoelectric plate and the reversed motion of the rotor can be obtained by driving the piezoelectric plate on the opposite side. The prototype stator with a size of 15 mm × 2.44 mm × 2 mm, operated at 44...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27896682/methods-of-power-force-velocity-profiling-during-sprint-running-a-narrative-review
#5
REVIEW
Matt R Cross, Matt Brughelli, Pierre Samozino, Jean-Benoit Morin
The ability of the human body to generate maximal power is linked to a host of performance outcomes and sporting success. Power-force-velocity relationships characterize limits of the neuromuscular system to produce power, and their measurement has been a common topic in research for the past century. Unfortunately, the narrative of the available literature is complex, with development occurring across a variety of methods and technology. This review focuses on the different equipment and methods used to determine mechanical characteristics of maximal exertion human sprinting...
November 28, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27893474/hypertrophy-and-explosive-reactive-functioning-in-sedentary-men-following-10-weeks-of-whole-body-vibration
#6
Jens Ebing, Ulf Gast, Christoph Hauptmann, Dieter Felsenberg, Daniel L Belavý
The objective of this study was to determine the impact of vertical (Power-plate; POW) and side-alternating (Galileo; GAL) whole-body vibration exercise on muscle mass and lower-limb neuromuscular function. Forty-three sedentary male subjects (18-30yr) randomized into three groups underwent two upper-body exercise sessions per week for 10 weeks. Two groups of subjects underwent additional squat exercises on the GAL (N=15) or POW (N=14) devices. The third group was control. On magnetic resonance imaging, volume of the thigh muscles was measured...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27881198/practical-experience-with-hole-free-phase-plates-for-cryo-electron-microscopy
#7
Michael Marko, Chyongere Hsieh, Eric Leith, David Mastronarde, Sohei Motoki
Phase plate (PP) imaging has proven to be valuable in transmission cryo electron microscopy of unstained, native-state biological specimens. Many PP types have been described, however until the recent implementation of the "hole-free" phase plate (HFPP), imaging has been challenging. We found the HFPP to be simple to construct and to set up in the transmission electron microscopy, but care in implementing automated data collection is needed. Performance may be variable, both initially and over time, thus it is important to monitor and evaluate image quality by observing the power spectrum...
November 24, 2016: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/27863051/tailoring-microbial-electrochemical-cells-for-production-of-hydrogen-peroxide-at-high-concentrations-and-efficiencies
#8
Michelle N Young, Mikaela J Links, Sudeep C Popat, Bruce E Rittmann, César I Torres
A microbial peroxide producing cell (MPPC) for H2 O2 production at the cathode was systematically optimized with minimal energy input. First, the stability of H2 O2 was evaluated using different catholytes, membranes, and catalyst materials. On the basis of these results, a flat-plate MPPC fed continuously using 200 mm NaCl catholyte at a 4 h hydraulic retention time was designed and operated, producing H2 O2 for 18 days. H2 O2 concentration of 3.1 g L(-1) H2 O2 with 1.1 Wh g(-1) H2 O2 power input was achieved in the MPPC...
November 10, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27857796/dwarf-with-dual-spinal-kyphotic-deformity-at-the-cervical-and-dorsal-spine-unassociated-with-odontoid-hypoplasia-surgical-management
#9
Guru Dutta Satyarthee, Dipanker Singh Mankotia
Morquio's syndrome is associated with systemic skeletal hypoplasia leading to generalized skeletal deformation. The hypoplasia of odontoid process is frequent association, which is responsible for atlantoaxial dislocation causing compressive myelopathy. However, development of sub-axial cervical kyphotic deformity unassociated with odontoid hypoplasia is extremely rare, and coexistence of dorsal kyphotic deformity is not reported in the western literature till date and represents first case. Current case is 16-year-old boy, who presented with severe kyphotic deformity of cervical spine with spastic quadriparesis...
July 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/27857320/efficient-generation-of-1-9%C3%A2-%C3%A2-w-yellow-light-by-cascaded-frequency-doubling-of-a-distributed-bragg-reflector-tapered-diode
#10
A K Hansen, M Christensen, D Noordegraaf, P Heist, E Papastathopoulos, V Loyo-Maldonado, O B Jensen, P M W Skovgaard
Watt-level yellow emitting lasers are interesting for medical applications, due to their high hemoglobin absorption, and for efficient detection of certain fluorophores. In this paper, we demonstrate a compact and robust diode-based laser system in the yellow spectral range. The system generates 1.9 W of single-frequency light at 562.4 nm by cascaded single-pass frequency doubling of the 1124.8 nm emission from a distributed Bragg reflector (DBR) tapered laser diode. The absence of a free-space cavity makes the system stable over a base-plate temperature range of 30 K...
November 10, 2016: Applied Optics
https://www.readbyqxmd.com/read/27846890/safety-and-feasibility-of-cell-based-therapy-of-autologous-bone-marrow-derived-mononuclear-cells-in-plate-stabilized-proximal-humeral-fractures-in-humans
#11
Caroline Seebach, Dirk Henrich, Simon Meier, Christoph Nau, Halvard Bonig, Ingo Marzi
BACKGROUND: Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP) significantly enhanced bone healing in a preclinical segmental defect model. Based on these results, we evaluated in a first clinical phase-I trial safety and feasibility of augmentation with preoperatively isolated autologous BMC seeded onto β-TCP in combination with angle stable plate fixation for the therapy of proximal humeral fractures as a potential alternative to autologous bone graft from the iliac crest...
November 15, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27833794/three-dimensional-paleohistology-of-the-scale-and-median-fin-spine-of-lophosteus-superbus-pander-1856
#12
Anna Jerve, Qingming Qu, Sophie Sanchez, Henning Blom, Per Erik Ahlberg
Lophosteus superbus is one of only a handful of probable stem-group osteichthyans known from the fossil record. First collected and described in the late 19th century from the upper Silurian Saaremaa Cliff locality in Estonia, it is known from a wealth of disarticulated scales, fin spines, and bone fragments. In this study we provide the first description of the morphology and paleohistology of a fin spine and scale from Lophosteus using virtual thin sections and 3D reconstructions that were segmented using phase-contrast synchrotron X-ray microtomography...
2016: PeerJ
https://www.readbyqxmd.com/read/27833426/the-imagos-of-some-enigmatic-members-of-the-hermanella-complex-ephemeroptera-leptophlebiidae
#13
Frederico F Salles, Eduardo Domínguez, Rodolfo Mariano, Roberta Paresque
The imago stages of three species of the Hermanella complex are described mostly based on material from Roraima, northern Brazil: Hydrosmilodon gilliesae, Hydromastodon sallesi and Leentvaaria palpalis. Male imagos of Hydrosmilodon gilliesae and Leentvaaria palpalis both have a pair of large, broad projections at the posterior margin of the styliger plate, nearly covering the penis lobes; in Leentvaaria palpalis, however, these projections are fused. The male imago of Hydromastodon sallesi resembles Hydrosmilodon plagatus in that both species have a styliger plate with a robust projection that is curved towards the penis lobes...
2016: ZooKeys
https://www.readbyqxmd.com/read/27831568/arqiv-hts-a-versatile-whole-organism-screening-platform-enabling-in-vivo-drug-discovery-at-high-throughput-rates
#14
David T White, Arife Unal Eroglu, Guohua Wang, Liyun Zhang, Sumitra Sengupta, Ding Ding, Surendra K Rajpurohit, Steven L Walker, Hongkai Ji, Jiang Qian, Jeff S Mumm
The zebrafish has emerged as an important model for whole-organism small-molecule screening. However, most zebrafish-based chemical screens have achieved only mid-throughput rates. Here we describe a versatile whole-organism drug discovery platform that can achieve true high-throughput screening (HTS) capacities. This system combines our automated reporter quantification in vivo (ARQiv) system with customized robotics, and is termed 'ARQiv-HTS'. We detail the process of establishing and implementing ARQiv-HTS: (i) assay design and optimization, (ii) calculation of sample size and hit criteria, (iii) large-scale egg production, (iv) automated compound titration, (v) dispensing of embryos into microtiter plates, and (vi) reporter quantification...
December 2016: Nature Protocols
https://www.readbyqxmd.com/read/27828522/experimental-and-numerical-characterization-of-a-new-45-kw-sub-el-sub-multisource-high-flux-solar-simulator
#15
Gaël Levêque, Roman Bader, Wojciech Lipiński, Sophia Haussener
The performance of a new high-flux solar simulator consisting of 18 × 2.5 kW<sub>el</sub> radiation modules has been evaluated. Grayscale images of the radiative flux distribution at the focus are acquired for each module individually using a water-cooled Lambertian target plate and a CCD camera. Raw images are corrected for dark current, normalized by the exposure time and calibrated with local absolute heat flux measurements to produce radiative flux maps with 180 µm resolution. The resulting measured peak flux is 1...
October 31, 2016: Optics Express
https://www.readbyqxmd.com/read/27828039/implementation-of-a-svwp-based-laser-beam-shaping-technique-for-generation-of-100-mj-level-picosecond-pulses
#16
J Adamonis, A Aleknavičius, K Michailovas, S Balickas, V Petrauskienė, T Gertus, A Michailovas
We present implementation of the energy-efficient and flexible laser beam shaping technique in a high-power and high-energy laser amplifier system. The beam shaping is based on a spatially variable wave plate (SVWP) fabricated by femtosecond laser nanostructuring of glass. We reshaped the initially Gaussian beam into a super-Gaussian (SG) of the 12th order with efficiency of about 50%. The 12th order of the SG beam provided the best compromise between large fill factor, low diffraction on the edges of the active media, and moderate intensity distribution modification during free-space propagation...
October 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27824962/a-novel-method-for-the-optimization-of-positron-emission-tomography-scanners-imaging-performance
#17
Christos M Michail, George E Karpetas, George P Fountos, Nektarios I Kalyvas, Ioannis G Valais, Christina Fountzoula, Antonis Zanglis, Ioannis S Kandarakis, George S Panayiotakis
OBJECTIVE: The aim of the present study was to propose a comprehensive method for positron emission tomography (PET) scanners image quality assessment, by simulation of a thin layer chromatography (TLC) flood source with a previously validated Monte Carlo model. METHODS AND MATERIALS: We used the GATE Monte Carlo package (GEANT4 application for tomographic emission) and the reconstructed images were obtained using the software for tomographic image reconstruction (STIR), with cluster computing...
November 8, 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27802701/high-sensitivity-photonic-time-stretch-electro-optic-sampling-of-terahertz-pulses
#18
C Szwaj, C Evain, M Le Parquier, P Roy, L Manceron, J-B Brubach, M-A Tordeux, S Bielawski
Single-shot recording of terahertz electric signals has recently become possible at high repetition rates, by using the photonic time-stretch electro-optic sampling (EOS) technique. However the moderate sensitivity of time-stretch EOS is still a strong limit for a range of applications. Here we present a variant enabling to increase the sensitivity of photonic time-stretch for free-propagating THz signals. The ellipticity of the laser probe is enhanced by adding a set of Brewster plates, as proposed by Ahmed et al...
October 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27800673/pressure-driven-chromatographic-separation-modes-in-self-enclosed-integrated-nanocapillaries
#19
Lian Duan, Zhen Cao, Levent Yobas
This study presents pressure-driven chromatographic separation characteristics of integrated nanofluidic channels (nanocapillaries) featuring distinct cross-sectional geometries: cylindrical, triangular, and rectangular profiles. Cylindrical and triangular nanocapillaries are self-enclosed robust conduits realized through standard semiconductor processing techniques using low-resolution photolithography. Specifically, capillaries in nominal radius 300 and 500 nm have been investigated for chromatographic separation in comparison to 750-nm-deep nanoslits as well as triangular capillaries featuring an inscribed circle about 500 nm in radius...
November 1, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27799529/mapping-intracellular-mechanics-on-micropatterned-substrates
#20
Kalpana Mandal, Atef Asnacios, Bruno Goud, Jean-Baptiste Manneville
The mechanical properties of cells impact on their architecture, their migration, intracellular trafficking, and many other cellular functions and have been shown to be modified during cancer progression. We have developed an approach to map the intracellular mechanical properties of living cells by combining micropatterning and optical tweezers-based active microrheology. We optically trap micrometer-sized beads internalized in cells plated on crossbow-shaped adhesive micropatterns and track their displacement following a step displacement of the cell...
November 15, 2016: Proceedings of the National Academy of Sciences of the United States of America
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