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https://www.readbyqxmd.com/read/27915308/self-directed-learning-readiness-of-asian-students-students-perspective-on-a-hybrid-problem-based-learning-curriculum
#1
Lukas D Leatemia, Astrid P Susilo, Henk van Berkel
Objectives: To identify the student's readiness to perform self-directed learning and the underlying factors influencing it on the hybrid problem based learning curriculum. Methods: A combination of quantitative and qualitative studies was conducted in five medical schools in Indonesia. In the quantitative study, the Self Directed Learning Readiness Scale was distributed to all students in all batches, who had experience with the hybrid problem based curriculum...
December 3, 2016: International Journal of Medical Education
https://www.readbyqxmd.com/read/27915258/testing-and-testing-positive-childhood-adversities-and-later-life-hiv-status-among-kenyan-women-and-their-partners
#2
Michael L Goodman, Lauren Raimer-Goodman, Catherine X Chen, Astrid Grouls, Stanley Gitari, Philip H Keiser
BACKGROUND: Adverse childhood experiences are a critical feature of lifelong health. No research assesses whether childhood adversities predict HIV-testing behaviors, and little research analyzes childhood adversities and later life HIV status in sub-Saharan Africa. METHODS: We use regression models with cross-sectional data from a representative sample (n = 1974) to analyze whether adverse childhood experiences, separately or as cumulative exposures, predict reports of later life HIV testing and testing HIV+ among semi-rural Kenyan women and their partners...
December 2, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27914649/nosocomial-outbreak-of-extensively-drug-resistant-pseudomonas-aeruginosa-associated-with-aromatherapy
#3
Astrid Mayr, Guido Hinterberger, Ingo H Lorenz, Peter Kreidl, Wolfgang Mutschlechner, Cornelia Lass-Flörl
An increase of extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) in various clinical specimens among intensive care unit patients (n = 7) initiated an outbreak investigation consisting of patient data analyses, control of adherence to infection control guidelines, microbiologic surveys, and molecular-based studies. XDR-PA was detected in a jointly used aroma-oil nursing bottle for aromatherapy. We implemented the restriction of oil sharing among patients. Hence, the outbreak was controlled successfully...
November 30, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27914187/enhanced-nutrition-improves-growth-and-increases-blood-adiponectin-concentrations-in-very-low-birth-weight-infants
#4
Elin W Blakstad, Sissel J Moltu, Britt Nakstad, Marit B Veierød, Kenneth Strømmen, Pétur B Júlíusson, Astrid N Almaas, Arild E Rønnestad, Kristin Brække, Christian A Drevon, Per O Iversen
BACKGROUND: Adequate nutrient supply is essential for optimal postnatal growth in very low birth weight (VLBW, birth weight<1,500 g) infants. Early growth may influence the risk of metabolic syndrome later in life. OBJECTIVE: To evaluate growth and blood metabolic markers (adiponectin, leptin, and insulin-like growth factor-1 (IGF-1)) in VLBW infants participating in a randomized nutritional intervention study. DESIGN: Fifty VLBW infants were randomized to an enhanced nutrient supply or a standard nutrient supply...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27910637/probing-the-electrical-impedance-of-thin-films-on-a-quartz-crystal-microbalance-qcm-making-use-of-frequency-shifts-and-piezoelectric-stiffening
#5
Astrid Peschel, Andreas Böttcher, Arne Langhoff, Diethelm Johannsmann
Using a temperature-responsive polymer film as an example, it was shown that a conventional quartz crystal microbalance (QCM) can probe a sample's electrical properties in addition to its thickness and softness. The film's electrical impedance was accessed by alternating between the driving voltage being applied to the front electrode and the back electrode. The opposing electrode was grounded in both cases. In the first configuration, the electrical properties of the sample do have an influence on the resonance frequency because of piezoelectric stiffening...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27908120/lipid-phase-behavior-studied-with-a-quartz-crystal-microbalance-a-technique-for-biophysical-studies-with-applications-in-screening
#6
Astrid Peschel, Arne Langhoff, Eva Uhl, Aruna Dathathreyan, Susanne Haindl, Diethelm Johannsmann, Ilya Reviakine
Quartz crystal microbalance (QCM) is emerging as a versatile tool for studying lipid phase behavior. The technique is attractive for fundamental biophysical studies as well applications because of its simplicity, flexibility, and ability to work with very small amounts of material crucial for biomedical studies. Further progress hinges on the understanding of the mechanism, by which a surface-acoustic technique such as QCM, senses lipid phase changes. Here, we use a custom-built instrument with improved sensitivity to investigate phase behavior in solid-supported lipid systems of different geometries (adsorbed liposomes and bilayers)...
November 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27907223/-mental-retirement-trajectories-of-work-engagement-preceding-retirement-among-older-workers
#7
Astrid de Wind, Fenna Rm Leijten, Trynke Hoekstra, Goedele A Geuskens, Alex Burdorf, Allard J van der Beek
Objectives Before actual retirement, employees may already distance themselves from work, which could be referred to as "mental retirement". However, trajectories of work motivation, ie, work engagement, have not been studied yet. The present study aimed to (i) identify different trajectories of work engagement among older workers approaching the retirement age, and (ii) examine their associations with actual retirement. Methods In total 3171 employees aged 55-62 years, who participated in the Dutch Study on Transitions in Employment, Ability and Motivation were included in this study...
December 1, 2016: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/27907183/activation-of-innate-and-adaptive-immunity-by-a-recombinant-human-cytomegalovirus-strain-expressing-an-nkg2d-ligand
#8
Adriana Tomić, Pavankumar R Varanasi, Mijo Golemac, Suzana Malić, Peggy Riese, Eva M Borst, Eva Mischak-Weissinger, Carlos A Guzmán, Astrid Krmpotić, Stipan Jonjić, Martin Messerle
Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical importance. Generally, it is believed that a live attenuated vaccine would best provide protective immunity against this tenacious pathogen. Here, we propose a strategy for an HCMV vaccine that aims at the simultaneous activation of innate and adaptive immune responses. An HCMV strain expressing the host ligand ULBP2 for the NKG2D receptor was found to be susceptible to control by natural killer (NK) cells, and preserved the ability to stimulate HCMV-specific T cells...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27906968/structural-and-functional-recovery-of-sensory-cilia-in-c-elegans-ift-mutants-upon-aging
#9
Astrid Cornils, Ashish K Maurya, Lauren Tereshko, Julie Kennedy, Andrea G Brear, Veena Prahlad, Oliver E Blacque, Piali Sengupta
The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely truncated sensory cilia of hypomorphic IFT mutants in C. elegans transiently elongate during a discrete period of adult aging leading to markedly improved sensory behaviors. Age-dependent restoration of cilia morphology occurs in structurally diverse cilia types and requires IFT...
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27905421/consistency-in-drug-response-profiling
#10
John Patrick Mpindi, Bhagwan Yadav, Päivi Östling, Prson Gautam, Disha Malani, Astrid Murumägi, Akira Hirasawa, Sara Kangaspeska, Krister Wennerberg, Olli Kallioniemi, Tero Aittokallio
No abstract text is available yet for this article.
November 30, 2016: Nature
https://www.readbyqxmd.com/read/27903640/differential-effect-of-visual-motion-adaption-upon-visual-cortical-excitability
#11
Astrid J A Lubeck, Angelique Van Ombergen, Hena Ahmad, Jelte E Bos, Floris L Wuyts, Adolfo M Bronstein, Qadeer Arshad
OBJECTIVE: 1) To probe the effects of visual motion adaptation upon, early visual and V5/MT cortical excitability and 2) To investigate whether or not changes in cortical excitability following visual motion adaptation are related to the degree of visual dependency, i.e. an overreliance on visual cues compared to vestibular or proprioceptive cues. METHODS: Participants were exposed to a roll-motion visual stimulus pre, during and post visual motion adaptation. At these stages 20 TMS pulses at phosphene-threshold values were applied over early visual and V5/MT cortical areas from which the probability of eliciting a phosphene was calculated...
November 30, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27903518/habituation-to-low-or-high-protein-intake-does-not-modulate-basal-or-postprandial-muscle-protein-synthesis-rates-a-randomized-trial
#12
Stefan Hm Gorissen, Astrid Mh Horstman, Rinske Franssen, Imre Wk Kouw, Benjamin T Wall, Nicholas A Burd, Lisette Cpgm de Groot, Luc Jc van Loon
BACKGROUND: Muscle mass maintenance is largely regulated by basal muscle protein synthesis rates and the ability to increase muscle protein synthesis after protein ingestion. To our knowledge, no previous studies have evaluated the impact of habituation to either low protein intake (LOW PRO) or high protein intake (HIGH PRO) on the postprandial muscle protein synthetic response. OBJECTIVE: We assessed the impact of LOW PRO compared with HIGH PRO on basal and postprandial muscle protein synthesis rates after the ingestion of 25 g whey protein...
November 30, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27900184/symptoms-and-risk-factors-of-depression-during-and-after-the-football-career-of-elite-female-players
#13
Birgit Prinz, Jiří Dvořák, Astrid Junge
BACKGROUND: The mental health of elite athletes has received increasing attention in recent years, but no study has evaluated the career-time prevalence of depression, and very few have analysed risk factors of mental health problems during or after the career. METHODS: 157 (response rate 64.1%) female players who played in the German First League answered an anonymous online survey on details of their football career, stressful and helpful conditions, depression and need of psychotherapeutic support during and after the football career...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27900164/prevalence-of-depression-and-anxiety-in-top-level-male-and-female-football-players
#14
Astrid Junge, Nina Feddermann-Demont
BACKGROUND: Scientific studies on the prevalence of mental health problems in elite athletes are rare, and most have had considerable methodological limitations, such as low response rate and heterogeneous samples. AIMS: To evaluate the prevalence of depression and anxiety in top-level football players in comparison to the general population, and to analyse potential risk factors. METHODS: Players of all first league (FL) and of four U-21 football teams in Switzerland were asked to answer a questionnaire on player's characteristics, the Centre of Epidemiologic Studies Depression Scale (CES-D) and the Generalized Anxiety Disorder (GAD-7) scale...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899373/influence-of-geolocation-and-ethnicity-on-the-phenotypic-expression-of-primary-sj%C3%A3-gren-s-syndrome-at-diagnosis-in-8310-patients-a-cross-sectional-study-from-the-big-data-sj%C3%A3-gren-project-consortium
#15
Pilar Brito-Zerón, Nihan Acar-Denizli, Margit Zeher, Astrid Rasmussen, Raphaele Seror, Elke Theander, Xiaomei Li, Chiara Baldini, Jacques-Eric Gottenberg, Debashish Danda, Luca Quartuccio, Roberta Priori, Gabriela Hernandez-Molina, Aike A Kruize, Valeria Valim, Marika Kvarnstrom, Damien Sene, Roberto Gerli, Sonja Praprotnik, David Isenberg, Roser Solans, Maureen Rischmueller, Seung-Ki Kwok, Gunnel Nordmark, Yasunori Suzuki, Roberto Giacomelli, Valerie Devauchelle-Pensec, Michele Bombardieri, Benedikt Hofauer, Hendrika Bootsma, Johan G Brun, Guadalupe Fraile, Steven E Carsons, Tamer A Gheita, Jacques Morel, Cristina Vollenveider, Fabiola Atzeni, Soledad Retamozo, Ildiko Fanny Horvath, Kathy Sivils, Thomas Mandl, Pulukool Sandhya, Salvatore De Vita, Jorge Sanchez-Guerrero, Eefje van der Heijden, Virginia Fernandes Moça Trevisani, Marie Wahren-Herlenius, Xavier Mariette, Manuel Ramos-Casals
OBJECTIVES: To analyse the influence of geolocation and ethnicity on the clinical presentation of primary Sjögren's syndrome (SjS) at diagnosis. METHODS: The Big Data Sjögren Project Consortium is an international, multicentre registry designed in 2014. By January 2016, 20 centres from five continents were participating. Multivariable logistic regression analyses were performed. RESULTS: We included 7748 women (93%) and 562 men (7%), with a mean age at diagnosis of primary SjS of 53 years...
November 29, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27898592/the-hepatitis-c-virus-nonstructural-protein-3-q80k-polymorphism-is-frequently-detected-and-transmitted-among-hiv-infected-msm-in-the-netherlands
#16
Astrid M Newsum, Cynthia K Y Ho, Faydra I Lieveld, Thijs J W van de Laar, Sylvie M Koekkoek, Sjoerd P Rebers, Jan T M van der Meer, Anne M J Wensing, Greet J Boland, Joop E Arends, Karel J van Erpecum, Maria Prins, Richard Molenkamp, Janke Schinkel
OBJECTIVES: The Q80K polymorphism is a naturally occurring resistance-associated variant in the hepatitis C virus (HCV) nonstructural protein 3 (NS3) region and is likely transmissible between hosts. This study describes the Q80K origin and prevalence among HCV risk groups in the Netherlands and examines whether Q80K is linked to specific transmission networks. DESIGN AND METHODS: Stored blood samples from HCV genotype 1a-infected patients were used for PCR and sequencing to reconstruct the NS3 maximum likelihood phylogeny...
January 2, 2017: AIDS
https://www.readbyqxmd.com/read/27894891/source-analysis-of-auditory-steady-state-responses-in-acoustic-and-electric-hearing
#17
Robert Luke, Astrid De Vos, Jan Wouters
Speech is a complex signal containing a broad variety of acoustic information. For accurate speech reception, the listener must perceive modulations over a range of envelope frequencies. Perception of these modulations is particularly important for cochlear implant (CI) users, as all commercial devices use envelope coding strategies. Prolonged deafness affects the auditory pathway. However, little is known of how cochlear implantation affects the neural processing of modulated stimuli. This study investigates and contrasts the neural processing of envelope rate modulated signals in acoustic and CI listeners...
November 25, 2016: NeuroImage
https://www.readbyqxmd.com/read/27894855/galloylquinic-acid-derivatives-from-copaifera-langsdorffii-leaves-display-gastroprotective-activity
#18
Erick V S Motta, Marivane Lemos, Juliana C Costa, Vilmar Cláudio Banderó-Filho, Astrid Sasse, Helen Sheridan, Jairo K Bastos
Nine new methylated galloylquinic acids were isolated from an aqueous fraction of Copaifera langsdorffii (Fabaceae-Caesalpinioideae) leaf hydroalcoholic extract (3-8, 11, 12, and 14), along with three known methylated galloylquinic acids (1, 2, and 15) and four galloylquinic acids (9, 10, 13, and 16). These compounds were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. They were further tested in a gastroprotection assay (Ethanol-HCl induced ulcer model in mice), in which all of them significantly reduced the total lesion area, and increased the cure ratio in comparison with pantoprazole...
November 25, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27894464/functional-neurological-symptoms-modulate-processing-of-emotionally-salient-stimuli
#19
Johanna Fiess, Brigitte Rockstroh, Roger Schmidt, Christian Wienbruch, Astrid Steffen
OBJECTIVE: Dysfunctional emotion processing has been discussed as a contributing factor to functional neurological symptoms (FNS) in the context of conversion disorder, and refers to blunted recognition and the expression of one's own feelings. However, the emotion processing components characteristic for FNS and/or relevant for conversion remain to be specified. With this goal, the present study targeted the initial, automatic discrimination of emotionally salient stimuli. METHODS: The magnetoencephalogram (MEG) was monitored in 21 patients with functional weakness and/or sensory disturbance subtypes of FNS and 21 healthy comparison participants (HC) while they passively watched 600 emotionally arousing, pleasant, unpleasant or neutral stimuli in a rapid serial visual presentation (RSVP) design...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27893910/use-of-jurisprudence-to-teach-professional-negligence
#20
Astrid D Oviedo
No abstract text is available yet for this article.
December 1, 2016: Journal of Nursing Education
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