keyword
MENU ▼
Read by QxMD icon Read
search

lafontaine

keyword
https://www.readbyqxmd.com/read/28228566/reduced-cognitive-function-in-patients-with-parkinson-disease-and-obstructive-sleep-apnea
#1
Victoria P Mery, Priti Gros, Anne-Louise Lafontaine, Ann Robinson, Andrea Benedetti, R John Kimoff, Marta Kaminska
OBJECTIVE: To assess the association between obstructive sleep apnea (OSA) and nonmotor symptoms (NMS), including cognitive dysfunction, in patients with Parkinson disease (PD). METHODS: Patients with idiopathic PD, recruited from a movement disorder clinic, underwent overnight polysomnography. OSA was defined as an apnea-hypopnea index (AHI) ≥15/h. PD severity was assessed using the Hoehn & Yahr (H&Y) scale and the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS)...
February 22, 2017: Neurology
https://www.readbyqxmd.com/read/28209210/a-direct-observation-method-for-auditing-large-urban-centers-using-stratified-sampling-mobile-gis-technology-and-virtual-environments
#2
Sean J V Lafontaine, M Sawada, Elizabeth Kristjansson
BACKGROUND: With the expansion and growth of research on neighbourhood characteristics, there is an increased need for direct observational field audits. Herein, we introduce a novel direct observational audit method and systematic social observation instrument (SSOI) for efficiently assessing neighbourhood aesthetics over large urban areas. METHODS: Our audit method uses spatial random sampling stratified by residential zoning and incorporates both mobile geographic information systems technology and virtual environments...
February 16, 2017: International Journal of Health Geographics
https://www.readbyqxmd.com/read/28187532/testicular-sperm-aspiration-tesa-for-infertile-couples-with-severe-or-complete-asthenozoospermia
#3
A H Al-Malki, K Alrabeeah, E Mondou, V Brochu-Lafontaine, S Phillips, A Zini
The aim of the study was to evaluate reproductive outcomes in a cohort of infertile couples with severe and complete asthenozoospermia undergoing TESA (testicular sperm aspiration) with ICSI. We conducted a retrospective study of 28 couples with complete or severe asthenozoospermia who underwent TESA between January 2010 and December 2015. We compared TESA-ICSI outcomes of these couples to ejaculate ICSI outcomes of 40 couples with severe asthenozoospermia treated during the same time period at our institution...
February 10, 2017: Andrology
https://www.readbyqxmd.com/read/28160690/use-of-concurrent-mixed-methods-combining-concept-mapping-and-focus-groups-to-adapt-a-health-equity-tool-in-canada
#4
Anne Guichard, Émilie Tardieu, Christian Dagenais, Kareen Nour, Ginette Lafontaine, Valéry Ridde
The aim of this project was to identify and prioritize a set of conditions to be considered for incorporating a health equity tool into public health practice. Concept mapping and focus groups were implemented as complementary methods to investigate the conditions of use of a health equity tool by public health organizations in Quebec. Using a hybrid integrated research design is a richer way to address the complexity of questions emerging from intervention and planning settings. This approach provides a deeper, operational, and contextualized understanding of research results involving different professional and organizational cultures, and thereby supports the decision-making process...
January 7, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28146328/many-places-called-home-the-adaptive-value-of-seasonal-adjustments-in-range-fidelity
#5
Alexandre Lafontaine, Pierre Drapeau, Daniel Fortin, Martin-Hugues St-Laurent
1.The vast majority of animal species display range fidelity, a space-use behaviour enhancing familiarity with local habitat features. While the fitness benefits of this behaviour have been demonstrated in a variety of taxa, some species or populations rather display infidelity, displacing their home range over time. Others, such as many ungulate species, show seasonal adjustments in their range fidelity to accommodate changes in the dominance of limiting factors or in the distribution of resources. 2.Few empirical studies have explored the adaptive value of seasonal adjustments in range fidelity...
February 1, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28120101/virus-induced-gene-silencing-in-rauwolfia-species
#6
Cyrielle Corbin, Florent Lafontaine, Liuda Johana Sepúlveda, Ines Carqueijeiro, Martine Courtois, Arnaud Lanoue, Thomas Dugé de Bernonville, Sébastien Besseau, Gaëlle Glévarec, Nicolas Papon, Lucia Atehortúa, Nathalie Giglioli-Guivarc'h, Marc Clastre, Benoit St-Pierre, Audrey Oudin, Vincent Courdavault
Elucidation of the monoterpene indole alkaloid biosynthesis has recently progressed in Apocynaceae through the concomitant development of transcriptomic analyses and reverse genetic approaches performed by virus-induced gene silencing (VIGS). While most of these tools have been primarily adapted for the Madagascar periwinkle (Catharanthus roseus), the VIGS procedure has scarcely been used on other Apocynaceae species. For instance, Rauwolfia sp. constitutes a unique source of specific and valuable monoterpene indole alkaloids such as the hypertensive reserpine but are also well recognized models for studying alkaloid metabolism, and as such would benefit from an efficient VIGS procedure...
January 24, 2017: Protoplasma
https://www.readbyqxmd.com/read/28119796/distal-radius-fractures-do-not-displace-following-splint-or-cast-removal-in-the-acute-postreduction-period-a-prospective-observational-study
#7
Brock D Foster, Lakshmanan Sivasundaram, Nathanael Heckmann, William C Pannell, Ram K Alluri, Alidad Ghiassi
Background Displacement of distal radius fractures has been previously described in the literature; however, little is known about fracture displacement following splint or cast removal at the initial clinic visit following reduction and immobilization. Purpose The purpose of this study was to evaluate risk factors for fracture displacement following splint or cast removal and physical examination in the acute postinjury period. Methods All patients with a closed distal radius fracture who presented to our orthopedic hand clinic within 3 weeks of injury were prospectively enrolled in our study...
February 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28094274/folivory-elicits-a-strong-defense-reaction-in-catharanthus-roseus-metabolomic-and-transcriptomic-analyses-reveal-distinct-local-and-systemic-responses
#8
Thomas Dugé de Bernonville, Inês Carqueijeiro, Arnaud Lanoue, Florent Lafontaine, Paloma Sánchez Bel, Franziska Liesecke, Karine Musset, Audrey Oudin, Gaëlle Glévarec, Olivier Pichon, Sébastien Besseau, Marc Clastre, Benoit St-Pierre, Victor Flors, Stéphane Maury, Elisabeth Huguet, Sarah E O'Connor, Vincent Courdavault
Plants deploy distinct secondary metabolisms to cope with environment pressure and to face bio-aggressors notably through the production of biologically active alkaloids. This metabolism-type is particularly elaborated in Catharanthus roseus that synthesizes more than a hundred different monoterpene indole alkaloids (MIAs). While the characterization of their biosynthetic pathway now reaches completion, still little is known about the role of MIAs during biotic attacks. As a consequence, we developed a new plant/herbivore interaction system by challenging C...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28071751/transcriptional-pausing-at-the-translation-start-site-operates-as-a-critical-checkpoint-for-riboswitch-regulation
#9
Adrien Chauvier, Frédéric Picard-Jean, Jean-Christophe Berger-Dancause, Laurène Bastet, Mohammad Reza Naghdi, Audrey Dubé, Pierre Turcotte, Jonathan Perreault, Daniel A Lafontaine
On the basis of nascent transcript sequencing, it has been postulated but never demonstrated that transcriptional pausing at translation start sites is important for gene regulation. Here we show that the Escherichia coli thiamin pyrophosphate (TPP) thiC riboswitch contains a regulatory pause site in the translation initiation region that acts as a checkpoint for thiC expression. By biochemically probing nascent transcription complexes halted at defined positions, we find a narrow transcriptional window for metabolite binding, in which the downstream boundary is delimited by the checkpoint...
January 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/28070316/consumers-preferences-for-fresh-yam-a-focus-group-study
#10
Carla Barlagne, Denis Cornet, Jean-Marc Blazy, Jean-Louis Diman, Harry Ozier-Lafontaine
In West and Central Africa and in the Caribbean, yam is one of the most important sources of carbohydrates and has a great potential to improve food security. The yam production sector is, however, now challenged by the satisfaction of evolving consumers' preferences. Since little is known about consumers' preferences regarding yams' characteristics, product quality, and the drivers of yam purchase, six focus group discussions were conducted (for a total of 31 participants). Among the purchasing criteria, price was considered more important than the others...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28031474/field-evaluation-of-insecticides-for-control-of-cabbage-maggot-diptera-anthomyiidae-in-rutabaga-in-canada
#11
W G van Herk, R S Vernon, D R Waterer, J H Tolman, P J Lafontaine, R P Prasad
At the time of this research, there were only two insecticides registered for control of cabbage maggot, Delia radicum L., in rutabaga in Canada, one of which (diazinon) will be deregistered by 2017, and resistance having been reported in some areas for the other (chlorpyrifos). To screen for chemistries to replace these organophosphates, and obtain efficacy data comparable between key vegetable brassica production areas in Canada, four small plot field studies were conducted concurrently in British Columbia, Saskatchewan, Ontario, and Quebec in 2009...
December 28, 2016: Journal of Economic Entomology
https://www.readbyqxmd.com/read/27997704/two-year-follow-up-outcomes-in-emotionally-focused-couple-therapy-an-investigation-of-relationship-satisfaction-and-attachment-trajectories
#12
Stephanie A Wiebe, Susan M Johnson, Marie-France Lafontaine, Melissa Burgess Moser, Tracy L Dalgleish, Giorgio A Tasca
Emotionally Focused Couple Therapy (EFT; The practice of emotionally focused couple therapy: Creating connection. New York, NY: Brunner-Routledge) is an evidence-based couple therapy that aims to create lasting change for couples (Clinical Psychology: Science and Practice, 6(1), 67-79). Although studies have demonstrated strong results in follow-up (Journal of Marital and Family Therapy, 28(4), 391-398), less is known about relationship functioning across time after therapy has ended. We modelled change in relationship satisfaction and attachment from pre-therapy through 24 months follow-up in 32 couples...
December 20, 2016: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/27941652/functional-divergence-of-poplar-histidine-aspartate-kinase-hk1-paralogs-in-response-to-osmotic-stress
#13
François Héricourt, Françoise Chefdor, Inès Djeghdir, Mélanie Larcher, Florent Lafontaine, Vincent Courdavault, Daniel Auguin, Franck Coste, Christiane Depierreux, Mirai Tanigawa, Tatsuya Maeda, Gaëlle Glévarec, Sabine Carpin
Previous works have shown the existence of protein partnerships belonging to a MultiStep Phosphorelay (MSP) in Populus putatively involved in osmosensing. This study is focused on the identification of a histidine-aspartate kinase, HK1b, paralog of HK1a. The characterization of HK1b showed its ability to homo- and hetero-dimerize and to interact with a few Histidine-containing Phosphotransfer (HPt) proteins, suggesting a preferential partnership in poplar MSP linked to drought perception. Furthermore, determinants for interaction specificity between HK1a/1b and HPts were studied by mutagenesis analysis, identifying amino acids involved in this specificity...
December 8, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27935785/romantic-attachment-and-physical-intimate-partner-violence-perpetration-in-a-chilean-sample-the-mediating-role-of-emotion-regulation-difficulties
#14
Mnica Guzmn-Gonzlez, Marie-France Lafontaine, Christine Levesque
Despite evidence that adult attachment insecurity has been linked to the perpetration of physical intimate violence, the mechanisms underlying this link need further exploration. The goal of this study was to evaluate the mediating role of emotion regulation difficulties in the association between romantic attachment and the use of physical intimate partner violence. To this end, 611 students recruited from Chilean universities completed the Experiences in Close Relationships questionnaire, the Difficulties in Emotion Regulation Scale, and the Revised Conflict Tactics Scales...
October 2016: Violence and Victims
https://www.readbyqxmd.com/read/27932974/patterns-of-longitudinal-neural-activity-linked-to-different-cognitive-profiles-in-parkinson-s-disease
#15
Atsuko Nagano-Saito, Mohamed S Al-Azzawi, Alexandru Hanganu, Clotilde Degroot, Béatriz Mejia-Constain, Christophe Bedetti, Anne-Louise Lafontaine, Valérie Soland, Sylvain Chouinard, Oury Monchi
Mild cognitive impairment in Parkinson's disease (PD) has been linked with functional brain changes. Previously, using functional magnetic resonance imaging (fMRI), we reported reduced cortico-striatal activity in patients with PD who also had mild cognitive impairment (MCI) vs. those who did not (non-MCI). We followed up these patients to investigate the longitudinal effect on the neural activity. Twenty-four non-demented patients with Parkinson's disease (non-MCI: 12, MCI: 12) were included in the study. Each participant underwent two fMRIs while performing the Wisconsin Card Sorting Task 20 months apart...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27924145/demographic-characteristics-associated-with-pregnant-and-postpartum-youth-referred-for-mental-health-services-in-a-community-outreach-center
#16
Sandhaya Norris, Mark L Norris, Emily Sibbald, Tim Aubry, Megan E Harrison, Genevieve Lafontaine, Jasmine Gandhi
OBJECTIVE: Pregnancy in youth is considered high risk from a number of different standpoints. At present, limited data has explored demographic factors associated with Canadian cohorts of pregnant and postpartum youth seeking mental health services. We aimed to describe demographic characteristics associated with pregnant and postpartum youth and young adults referred for mental health services in the community and to compare this with data drawn from a hospital-based perinatal mental health clinic...
2016: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27918935/depressive-symptoms-in-parkinson-s-disease-correlate-with-cortical-atrophy-over-time
#17
Alexandru Hanganu, Marie-Andrée Bruneau, Clotilde Degroot, Christophe Bedetti, Béatriz Mejia-Constain, Anne-Louise Lafontaine, Sylvain Chouinard, Oury Monchi
INTRODUCTION: Depressive symptoms are very common in patients with Parkinson's disease (PD) and have a significant impact on the quality of life. METHODS: The present study analyzed the correlations between over-time changes in depressive symptoms and gray matter parameters of cortical thickness and subcortical volumes in non-demented PD patients. RESULTS: A significant correlation was observed, between increased scores for depression over time and lower cortical thickness over time in the right temporo-parietal junction, right occipital medial region, right dorsolateral prefrontal cortex, right posterior cingulate region, left middle temporal as well as left supplementary motor area...
February 2017: Brain and Cognition
https://www.readbyqxmd.com/read/27911188/tuning-the-ribosome-the-influence-of-rrna-modification-on-eukaryotic-ribosome-biogenesis-and-function
#18
Katherine E Sloan, Ahmed S Warda, Sunny Sharma, Karl-Dieter Entian, Denis L J Lafontaine, Markus T Bohnsack
rRNAs are extensively modified during their transcription and subsequent maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed either by snoRNA-guided or by stand-alone enzymes, generally stabilize the structure of the ribosome. However, they also cluster at functionally important sites of the ribosome, such as the peptidyltransferase center and the decoding site, where they facilitate efficient and accurate protein synthesis. The recent identification of sites of substoichiometric 2'-O-methylation and pseudouridylation has overturned the notion that all rRNA modifications are constitutively present on ribosomes, highlighting nucleotide modifications as an important source of ribosomal heterogeneity...
December 2, 2016: RNA Biology
https://www.readbyqxmd.com/read/27816489/pkc%C3%AE-induced-phosphorylations-control-the-ability-of-fra-1-to-stimulate-gene-expression-and-cancer-cell-migration
#19
Karine Belguise, Sara Cherradi, Awa Sarr, Florence Boissière, Nathalie Boulle, Joëlle Simony-Lafontaine, Valérie Choesmel-Cadamuro, Xiaobo Wang, Dany Chalbos
The AP-1 transcription factor Fra-1 is aberrantly expressed in a large number of cancers and plays crucial roles in cancer development and progression by stimulating the expression of genes involved in these processes. However, the control of Fra-1 transactivation ability is still unclear and here we hypothesized that PKCθ-induced phosphorylation could be necessary to obtain a fully active Fra-1 protein. Using MCF7 stable cells overexpressing equivalent levels of unphosphorylated Fra-1 or PKCθ-phosphorylated Fra-1, we showed that PKCθ-induced phosphorylation of Fra-1 was crucial for the stimulation of MMP1 and IL6 expression...
January 28, 2017: Cancer Letters
https://www.readbyqxmd.com/read/27811818/a-new-paramathes-boursin-1954-lepidoptera-noctuidae-species-from-china
#20
Aidas Saldaitis, Peter Gyulai
The genera Paramathes was erected by Boursin (1954) for four Xestia-like species, however with slight differences from the Xestia Hübner in their clasping apparatuses. Later this generic name was synonymised with Xestia by Lafontaine (1998). Gyulai, Ronkay, & Saldaitis (2011) treated Paramathes as the subgenera of Xestia. The most recent revision of the Paramathes is presented in the volume 8 of the Taxonomic Atlas of the Eurasian and North African Noctuoidea (Varga et al. 2015), in which authors return to the original concept of Boursin (1954), taking into consideration the configuration of the carinal plate of aedeagus and the bar in the basal area of the vesica in the males and the flap-like shape of the two bilateral lobes of the strongly sclerotized antrum in the females...
October 10, 2016: Zootaxa
keyword
keyword
93760
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"