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https://www.readbyqxmd.com/read/29027993/current-pharmacotherapy-for-obesity
#1
REVIEW
Gitanjali Srivastava, Caroline M Apovian
More than one-third of adults in the USA have obesity, which causes, exacerbates or adversely impacts numerous medical comorbidities, including diabetes mellitus and cardiovascular disease. Despite intensive lifestyle modifications, the disease severity warrants further aggressive intervention, including pharmacotherapy, medical devices and bariatric surgery. Noninvasive anti-obesity drugs have thus now resurfaced as targeted adjunctive therapeutic approaches to intensive lifestyle intervention, bridging the gap between lifestyle and bariatric surgery...
October 13, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29027775/tactics-for-reducing-opioids-consumption-for-bariatric-surgery
#2
Steven R Clendenen
No abstract text is available yet for this article.
October 12, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29026515/intussusception-as-a-complication-of-bariatric-surgery-in-pregnant-patients-report-of-one-case-and-revision-of-the-literature
#3
Luis A Boccalatte, Juan Achaval Rodríguez, Axel Beskow, Demetrio Cavadas, Wright Fernando
Occlusive complications after a laparoscopic Roux-in Y gastric bypass (LRYGB), appear mainly as fibrous membranes of wounds, internal hernias or intussusception. Intussusception after a bariatric surgery occurs in 0.1-0.3% of the cases. We present a case of intussusception in a pregnant patient after a LRYGB.
October 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29026186/about-bariatric-surgery-and-diabetic-retinopathy-the-debate-continues
#4
A E Pontiroli, C Merlotti, V Ceriani, A Morabito
No abstract text is available yet for this article.
October 13, 2017: Eye
https://www.readbyqxmd.com/read/29025827/influence-of-social-deprivation-on-provision-of-bariatric-surgery-10-year-comparative-ecological-study-between-two-uk-specialist-centres
#5
Shivam Bhanderi, Mushfique Alam, Jacob Henry Matthews, Gavin Rudge, Hamish Noble, David Mahon, Martin Richardson, Richard Welbourn, Paul Super, Rishi Singhal
OBJECTIVE: To investigate the effect of residential location and socioeconomic deprivation on the provision of bariatric surgery. DESIGN: Retrospective cross-sectional ecological study. SETTING: Patients resident local to one of two specialist bariatric units, in different regions of the UK, who received obesity surgery between 2003 and 2013. METHODS: Demographic data were collected from prospectively collected databases...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025246/vaspin-mrna-levels-in-the-liver-of-morbidly-obese-women-with-nonalcoholic-fatty-liver-disease
#6
Marek Waluga, Michał Kukla, Michał Żorniak, Marta Grabiec, Maciej Kajor, Michał Dyaczyński, Grzegorz Kowalski, Dominika Żądło, Agnieszka Berdowska, Rafał Kotulski, Rafał J Bułdak, Tomasz Sawczyn, Ewa Waluga, Paweł Olczyk, Marek Hartleb
The aim of this study was to evaluate hepatic vaspin mRNA in morbidly obese women with nonalcoholic fatty liver disease (NAFLD) and to look for its relationships with metabolic and histopathological features. The study included 56 severely obese women who underwent intraoperative wedge liver biopsy during bariatric surgery. Hepatic vaspin mRNA was assessed by quantitative real-time PCR. Vaspin mRNA found in all included patients was markedly higher in patients with body mass index (BMI) ≥ 40 kg/m2 (4.59 ±3...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/29025225/lymphatic-and-sensory-function-of-the-upper-limb-after-brachioplasty-in-post-bariatric-massive-weight-loss-patients
#7
Stefano Gentileschi, Maria Servillo, Gabriella Ferrandina, Marzia Salgarello
Background: Varied deformities of the upper arm are common after massive weight loss. Brachioplasty techniques have been successively modified to improve aesthetic outcomes and avoid complications, especially lymphedema and sensory damage. Objectives: The authors evaluated lymphatic drainage and sensory function of the upper limbs after brachioplasty performed with a double-ellipse marking technique, a medial incision, superficial undermining, and posterior arm liposuction...
October 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29024428/heat-shock-protein-60-in-obesity-effect-of-bariatric-surgery-and-its-relation-to-inflammation-and-cardiovascular-risk
#8
Henrike Sell, Christine Poitou, Christiane Habich, Jean-Luc Bouillot, Jürgen Eckel, Karine Clément
OBJECTIVE: Heat shock protein 60 (Hsp60) is an adipokine, and its serum concentrations are higher in patients with obesity compared to lean patients. This study aimed to analyze the effect of bariatric surgery on circulating concentrations of Hsp60 in morbid obesity and their correlation with inflammation and metabolic and cardiovascular risk. METHODS: Fifty-three females with morbid obesity undergoing bariatric surgery were enrolled. Serum parameters and anthropometric measures were obtained at baseline and 3 to 12 months post surgery...
October 11, 2017: Obesity
https://www.readbyqxmd.com/read/29023333/clinical-indicators-of-postoperative-bleeding-in-bariatric-surgery
#9
Andras B Fecso, Timothy Samuel, Ahmad Elnahas, Sanjeev Sockalingam, Timothy Jackson, Fayez Quereshy, Allan Okrainec
The purpose of this study was to evaluate the relationship between patient, clinical and laboratory characteristics, and bleeding after bariatric surgery. A retrospective chart review was performed for all patients, who underwent a laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy at our institution between March 2012 and May 2014. In total, 788 patients were included in this study. Seventeen patients had postoperative bleeding. The demographics, comorbidities, and preoperative medications were similar between the groups...
October 11, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29023257/impact-of-abdominal-lipectomy-on-post-sleeve-gastrectomy-surgery-weight-loss
#10
Turkia M Abbed, Raquel Gonzalez-Heredia, Lisa Sanchez-Johnsen, Enrique F Elli, Mimis N Cohen
BACKGROUND: Abdominal lipectomy after bariatric surgery is recommended because of residual excess skin resulting in difficulty with maintaining hygiene, recurrent infections, and functional impairment, interfering with daily activities. There is a dearth of literature examining weight loss outcomes in patients undergoing abdominal lipectomy post sleeve gastrectomy (SG). The purpose of this study was to examine whether post-SG patients who received abdominal lipectomy achieved greater percent excess weight loss (%EWL) than post-SG patients who did not receive abdominal lipectomy...
November 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29022228/the-development-and-treatment-of-a-food-phobia-after-bariatric-surgery
#11
Lisa Renee Miller-Matero, Anne Eshelman
No abstract text is available yet for this article.
October 11, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29022218/an-examination-of-the-mechanisms-and-personality-traits-underlying-food-addiction-among-individuals-with-severe-obesity-awaiting-bariatric-surgery
#12
Anne-Sophie Ouellette, Christopher Rodrigue, Simone Lemieux, André Tchernof, Laurent Biertho, Catherine Bégin
PURPOSE: The aetiology underlying addiction has often been investigated to shed more light on the factors contributing to the development and maintenance of various disorders. In the field of addictive eating behaviours, data on the aetiological factors related to food addiction (FA) in the bariatric context remain scarce. The present study aimed to explore mechanisms and variables underlying FA among individuals suffering from severe obesity and awaiting bariatric surgery. METHODS: Participants (N = 146) were recruited at the Quebec Heart and Lung Institute during their pre-operative visit and were invited to complete questionnaires...
October 11, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29020674/obesity-and-type-2-diabetes-two-diseases-with-a-need-for-combined-treatment-strategies-easo-can-lead-the-way
#13
Deborah R Leitner, Gema Frühbeck, Volkan Yumuk, Karin Schindler, Dragan Micic, Euan Woodward, Hermann Toplak
Obesity is a chronic metabolic disease affecting adults and children worldwide. It has become one of the leading causes of death, as obesity is known to be the main risk factor for a number of non-communicable diseases, in particular type 2 diabetes. This close relationship led to the connotation 'diabesity', highlighting the fact that the majority of individuals with diabetes are overweight or obese. Until today the BMI is still used to classify overweight and obesity. Since reduced muscle mass is highly prevalent throughout the BMI range, the measurement of body composition is strongly recommended...
October 12, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29019715/post-operative-insulin-requirements-in-bariatric-surgery
#14
Danielle M Diemer, Karen L Terry, Melissa Matthews, Ellen Romich, Heather Saran, M Cecilia Lansang
Though insulin dose reduction months after surgery is well-studied, there are limited data on immediate post-operative changes. OBJECTIVES: 1) To determine perioperative glycemic control in patients with type 2 diabetes (DM) on insulin who have undergone Roux-en-Y gastric bypass, and 2) to compare pre- and post-operative insulin regimens and dosage in these patients. RESEARCH DESIGN AND METHODS: A retrospective chart review was conducted on patients with type 2 DM, on insulin, who underwent Roux-en-Y bariatric surgery...
October 11, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29019565/sleeve-gastrectomy-and-fundoplication-as-a-single-procedure-in-patients-with-obesity-and-gastroesophageal-reflux
#15
Juan Pablo Lasnibat, Italo Braghetto, Luis Gutierrez, Felipe Sanchez
BACKGROUND: Bariatric surgery in Chile has seen an exponential increase in recent years, especially in sleeve gastrectomy. Its use is currently discussed in patients suffering from gastroesophageal reflux disease. Different options have been considered for the management of these patients but up to now laparoscopic Roux-en-Y gastric bypass seems to be the best option. Sleeve gastrectomy plus concomitant fundoplication or hiatal hernia repair also has been suggested in patients having reflux or small hiatal hernia...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29019151/bariatric-surgery-is-acceptably-safe-in-obese-inflammatory-bowel-disease-patients-analysis-of-the-nationwide-inpatient-sample
#16
Fateh Bazerbachi, Tarek Sawas, Eric J Vargas, Samir Haffar, Parakkal Deepak, John B Kisiel, Edward V Loftus, Barham K Abu Dayyeh
BACKGROUND: The prevalence of obesity in patients with inflammatory bowel disease (IBD) has increased over the past decades. Data to support the safety of bariatric surgery (BAR) in IBD remain scarce. Our aim was to evaluate the safety and early postoperative complications of BAR in IBD patients. METHODS: We used the Nationwide Inpatient Sample (NIS) 2011, 2012, and 2013 to perform a cohort study. The study group was all hospitalized patients between ages 18-90 years who underwent BAR with a discharge diagnosis of IBD as per the Ninth International Classification of Diseases codes (ICD-9)...
October 10, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29016506/contraception-and-conception-after-bariatric-surgery
#17
Marie N Menke, Wendy C King, Gretchen E White, Gabriella G Gosman, Anita P Courcoulas, Gregory F Dakin, David R Flum, Molly J Orcutt, Alfons Pomp, Walter J Pories, Jonathan Q Purnell, Kristine J Steffen, Bruce M Wolfe, Susan Z Yanovski
OBJECTIVE: To examine contraceptive practices and conception rates after bariatric surgery. METHODS: The Longitudinal Assessment of Bariatric Surgery-2 is a multicenter, prospective cohort study of adults undergoing first-time bariatric surgery as part of routine clinical care at 10 U.S. hospitals. Recruitment occurred between 2005 and 2009. Participants completed preoperative and annual postsurgical assessments for up to 7 years until January 2015. This report was restricted to women 18-44 years old with no history of menopause, hysterectomy, or estrogen and progesterone therapy...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28994775/assessment-of-human-adipose-tissue-microvascular-function-using-videomicroscopy
#18
Melissa G Farb, Song-Young Park, Shakun Karki, Noyan Gokce
While obesity is closely linked to the development of metabolic and cardiovascular disease, little is known about mechanisms that govern these processes. It is hypothesized that pro-atherogenic mediators released from fat tissues particularly in association with central/visceral adiposity may promote pathogenic vascular changes locally and systemically, and the notion that cardiovascular disease may be the consequence of adipose tissue dysfunction continues to evolve. Here, we describe a unique method of videomicroscopy that involves analysis of vasodilator and vasoconstrictor responses of intact small human arterioles removed from the adipose depot of living human subjects...
September 29, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28988855/grazing-in-adults-with-obesity-and-eating-disorders-a-systematic-review-of-associated-clinical-features-and-meta-analysis-of-prevalence
#19
REVIEW
Andreea I Heriseanu, Phillipa Hay, Laura Corbit, Stephen Touyz
Grazing, the unstructured, repetitive eating of small amounts of food, is a pattern of eating which has been associated with negative outcomes following bariatric surgery. Less is known about grazing in eating disorders and in non-surgical obese samples. This review aims to critically examine the existing research on the prevalence of grazing, associated treatment outcomes, and clinical correlates in adults with eating disorders and/or obesity, in clinical and community settings. A systematic electronic database search yielded 38 studies which met inclusion criteria for the review...
September 15, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28988235/readmissions-and-emergency-department-visits-after-bariatric-surgery-at-saudi-arabian-hospital-the-rates-reasons-and-risk-factors
#20
Anwar Ahmed, Doaa AlBuraikan, Bashayr ALMuqbil, Wijdan AlJohi, Wala Alanazi, Budor AlRasheed
BACKGROUND: Saudi Arabian hospital readmissions and emergency department (ED) visits following bariatric surgery and discharge have never been investigated. This study aimed to evaluate the rates and reasons of hospital readmissions and ED visits related to surgical weight loss interventions at the King Abdulaziz Medical City - Riyadh. METHODS: We conducted a retrospective cohort study on 301 patients who underwent bariatric surgery between January 2011 and July 2016...
October 7, 2017: Obesity Facts
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