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https://www.readbyqxmd.com/read/29911733/is-laparoscopic-sleeve-gastrectomy-for-asian-super-obese-a-safe-and-effective-procedure
#1
Hannah Jh Ng, Guowei Kim, Claire Alexandra Z Chew, Moe Thu San, Jimmy By So, Asim Shabbir
INTRODUCTION: Outcomes of bariatric surgery for super obese Asians are not well reported. We aimed to compare short-term outcomes of laparoscopic sleeve gastrectomy (LSG) in Asian patients with body mass index (BMI) <47.5 kg/m2 to those with BMI •••••• ≥47.5 kg/m2 . MATERIALS AND METHODS: A total of 272 patients from Singapore university hospital who underwent LSG from 2008 to 2015 with a follow-up of at least 6 months were included in the study. Primary endpoint was weight loss at 1-year and 3-years...
May 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29910989/neural-correlates-of-executive-functions-in-patients-with-obesity
#2
Ming-Chou Ho, Vincent Chin-Hung Chen, Seh-Huang Chao, Ching-Tzu Fang, Yi-Chun Liu, Jun-Cheng Weng
Obesity is one of the most challenging problems in human health and is recognized as an important risk factor for many chronic diseases. It remains unclear how the neural systems (e.g., the mesolimbic "reward" and the prefrontal "control" neural systems) are correlated with patients' executive function (EF), conceptualized as the integration of "cool" EF and "hot" EF. "Cool" EF refers to relatively abstract, non-affective operations such as inhibitory control and mental flexibility...
2018: PeerJ
https://www.readbyqxmd.com/read/29910974/does-bariatric-surgery-influence-plasma-levels-of-fetuin-a-and-leukocyte-cell-derived-chemotaxin-2-in-patients-with-type-2-diabetes-mellitus
#3
Hsien-Hao Huang, Chun Yeh, Jung-Chien Chen, Tzong-Hsi Lee, Shu-Chun Chen, Wei-Jei Lee, Chih-Yen Chen
Background: Fetuin-A and leukocyte cell-derived chemotaxin-2 (LECT-2) are liver-derived proteins. Fetuin-A is an independent risk factor for type 2 diabetes (T2D) and obese patients with T2D have higher plasma fetuin-A levels than those without T2D. LECT-2 has positive correlation with the severity of both obesity and insulin resistance. The changes in plasma fetuin-A are not consistent after bariatric surgery and no studies have investigated the changes in LECT-2 on the obese patients with T2D after bariatric surgery...
2018: PeerJ
https://www.readbyqxmd.com/read/29909517/metabolic-parameters-weight-loss-and-comorbidities-4-years-after-roux-en-y-gastric-bypass-and-sleeve-gastrectomy
#4
Corey J Lager, Nazanene H Esfandiari, Yingying Luo, Angela R Subauste, Andrew T Kraftson, Morton B Brown, Oliver A Varban, Rasimcan Meral, Ruth B Cassidy, Catherine K Nay, Amy L Lockwood, Darlene Bellers, Colleen M Buda, Elif A Oral
BACKGROUND: Sleeve gastrectomy (LSG) is now the predominant bariatric surgery performed, yet there is limited long-term data comparing important outcomes between LSG and Roux-en-Y gastric bypass (RYGB). This study compares weight loss and impact on comorbidities of the two procedures. METHODS: We retrospectively evaluated weight, blood pressure, hemoglobin A1c, cholesterol, and medication use for hypertension, diabetes, and hyperlipidemia at 1-4 years post-operatively in 380 patients who underwent RYGB and 334 patients who underwent LSG at the University of Michigan from January 2008 to November 2013...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909515/influence-of-biliopancreatic-diversion-on-pregnancy-outcomes-in-comparison-to-other-bariatric-surgery-procedures
#5
S De Carolis, A Botta, Gelsomina Del Sordo, R Guerrisi, S Salvi, M P De Carolis, A Iaconelli, P Giustacchini, M Raffaelli, A Lanzone
BACKGROUND: Pregnancy after bariatric surgery (BS) has an increased risk for small-for-gestational-age infants (SGA), shorter length of gestation, and probably perinatal mortality. The aim of this study was to investigate if biliopancreatic diversion could impair pregnancy outcomes in comparison to other bariatric surgery procedures. METHODS: We conducted a cohort retrospective single-center study in 65 women before and after BS. Thirty-one pregnancies occurred before BS, while 109 after BS, amongst which n = 51 after biliopancreatic diversion (BPD) and n = 58 after non-malabsorptive procedures...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909514/mid-term-4-year-outcomes-with-single-anastomosis-duodenal-ileal-bypass-with-sleeve-gastrectomy-surgery-at-a-single-us-center
#6
Hinali Zaveri, Amit Surve, Daniel Cottam, Austin Cottam, Walter Medlin, Christina Richards, LeGrand Belnap, Samuel Cottam, Benjamin Horsley
BACKGROUND: Single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) is a modification of Roux-en-Y duodenal switch (RYDS). Long-term data on this operation is lacking in the literature. We reviewed our mid-term data of this RYDS modification. PURPOSE: To analyze the outcomes with SADI-S at 4 years. METHODS: Data from patients who underwent a primary SADI-S procedure performed by three surgeons at a single institution from June 2013 through February 2018 were retrospectively reviewed...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909512/the-effectiveness-of-endoscopic-gastroplasty-for-obesity-treatment-according-to-fda-thresholds-systematic-review-and-meta-analysis-based-on-randomized-controlled-trials
#7
REVIEW
Antonio Coutinho Madruga-Neto, Wanderley Marques Bernardo, Diogo Turiani Hourneaux de Moura, Vitor Ottoboni Brunaldi, Rafael Krieger Martins, Iatagan Rocha Josino, Eduardo Turiani Hourneaux de Moura, Thiago Ferreira de Souza, Marco Aurélio Santo, Eduardo Guimarães Hourneaux de Moura
Endoscopic bariatric therapies (EBTs) are promising alternatives to conventional surgery for obesity. The aim of this study is to compare efficacy and safety through a systematic review and meta-analysis of the endoscopic gastroplasty techniques versus conservative treatment. We searched MEDLINE, EMBASE, Cochrane CENTRAL, Lilacs/Bireme. Randomized controlled trials (RCTs) enrolling obese patients comparing endoscopic gastroplasty to sham or diet/exercise were considered eligible. Among 6014 records, three RCTs were selected for meta-analysis...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909510/impact-on-dyslipidemia-after-laparoscopic-sleeve-gastrectomy
#8
Agustina Vigilante, Franco Signorini, Marcos Marani, Virginia Paganini, Germán Viscido, Luciano Navarro, Lucio Obeide, Federico Moser
BACKGROUND: Improvement of dyslipidemia is an important benefit of bariatric surgery. The benefits of laparoscopic sleeve gastrectomy (LSG) among dyslipidemia are still a matter of debate. METHODS: We conducted a retrospective descriptive study between 2010 and 2013. Obese patients undergoing LSG, with recorded dyslipidemia at admission and a follow-up for at least 1 year, were included for analysis. Demographic characteristics, medication in use, and a complete lipid profile were collected before surgery...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29909509/utilization-of-public-system-for-gastric-bands-placed-by-private-providers-a-4-year-population-based-analysis-in-ontario-canada
#9
Kristel Lobo Prabhu, Allan Okrainec, Azusa Maeda, Refik Saskin, David Urbach, Chaim M Bell, Timothy D Jackson
Laparoscopic adjustable gastric band (LAGB) placement remains a common bariatric procedure. While LAGB procedure is performed within private clinics in most Canadian provinces, public health care is often utilized for LAGB-related reoperations. We identified 642 gastric band removal procedures performed in Ontario from 2011 to 2014 using population-level administrative data. The number of procedures performed increased annually from 101 in 2011 to 220 in 2014. Notably, 54.7% of the patients required laparotomy, and 17...
June 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29908684/accuracy-of-total-energy-expenditure-predictive-equations-after-a-massive-weight-loss-induced-by-bariatric-surgery
#10
Michele Novaes Ravelli, Dale A Schoeller, Alex Harley Crisp, Natalie M Racine, Karina Pfrimer, Irineu Rasera Junior, Maria Rita Marques de Oliveira
BACKGROUND AND AIMS: Predictive equations remain the clinical tool of choice to estimate the energy expenditure, however, poor accuracy has been found when applied in patients with severe obesity. The aim of this study was to test the accuracy of the total energy expenditure (TEE) those obtained by predictive equations of resting energy expenditure (REE) times individual estimates of metabolic equivalents (MET), taking as reference the TEE measured by doubly labeled water (DLW), before, six and twelve months after bariatric surgery...
August 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29907965/the-genetic-architecture-of-diet-induced-hepatic-fibrosis-in-mice
#11
Simon T Hui, Zeyneb Kurt, Iina Tuominen, Frode Norheim, Richard C Davis, Calvin Pan, Darwin L Dirks, Clara E Magyar, Samuel W French, Karthickeyan Chella Krishnan, Simon Sabir, Francisco Campos-Pérez, Nahum Méndez-Sánchez, Luis Macías-Kauffer, Paola León-Mimila, Samuel Canizales-Quinteros, Xia Yang, Simon W Beaven, Adriana Huertas-Vazquez, Aldons J Lusis
We report the genetic analysis of a "humanized" hyperlipidemic mouse model for progressive nonalcoholic steatohepatitis (NASH) and fibrosis. Mice carrying transgenes for human APOE*3-Leiden and CETP and fed a "Western" diet were studied on the genetic backgrounds of over 100 inbred mouse strains. The mice developed hepatic inflammation and fibrosis that was highly dependent on genetic background, with vast differences in the degree of fibrosis. Histological analysis showed features characteristic of human NASH, including macrovesicular steatosis, hepatocellular ballooning, inflammatory foci and pericellular collagen deposition...
June 16, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29907941/the-clinical-outcome-of-postoperative-invasive-fungal-infections-complicating-laparoscopic-sleeve-gastrectomy
#12
Yoav Bichovsky, Leonid Koyfman, Michael Friger, Boris Kirshtein, Abraham Borer, Gilbert Sebbag, Dmitry Frank, Amit Frenkel, Jochanan G Peiser, Moti Klein, Evgeni Brotfain
PURPOSE: Peritonitis is a major complication of bariatric surgery due to direct damage to the natural barriers to infection. Most such secondary peritoneal infections are caused by Gram-negative microorganisms; however, under certain conditions, Candida species can infect the peritoneal cavity following bariatric surgery. MATERIALS AND METHODS: We retrospectively analyzed the clinical and microbiological data of morbidly obese patients who suffered infectious complications following laparoscopic sleeve gastrectomy (LSG) at the Soroka Medical Center between January 2010 and June 2015...
June 15, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29907540/american-society-for-metabolic-and-bariatric-surgery-review-of-the-literature-on-one-anastomosis-gastric-bypass
#13
Manish Parikh, Dan Eisenberg, Jason Johnson, Maher El-Chaar
The following review is being published by the American Society for Metabolic and Bariatric Surgery in response to numerous inquiries made to the Society by patients, physicians, society members, hospitals, and others regarding one-anastomosis gastric bypass as a primary treatment for obesity or metabolic disease. The review is based on current clinical knowledge, expert opinion, and published peer-reviewed scientific evidence available at this time. The review is not intended as, and should not be construed as, stating or establishing a local, regional, or national standard of care...
May 9, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29906810/endoscopic-gastric-reduction-with-an-endoluminal-suturing-device-a-multicenter-prospective-trial-with-1-year-follow-up
#14
Vincent Huberty, Evzen Machytka, Ivo Boškoski, Marie Barea, Guido Costamagna, Jacques Deviere
BACKGROUND:  Obesity is the pandemic disease of this century. Surgery is the only effective treatment but cannot be offered to every patient. Endoscopic sutured gastroplasty is a minimally invasive technique that may potentially fill the gap between surgery and behavioral therapy. In this study, we prospectively investigated the efficacy and safety of a novel suturing device. METHODS:  After a pre-bariatric multidisciplinary work-up, class 1 and 2 obese patients were included...
June 15, 2018: Endoscopy
https://www.readbyqxmd.com/read/29905880/-black-esophagus-and-gastric-volvulus-following-slipped-laparoscopic-adjustable-gastric-band
#15
REVIEW
Carolyn Moore, Leslie Ray Matthews, Omar Danner, Assad Taha, Aviva Bashan-Gilzenrat, Jonathan Nguyen, Ed Childs, Kahdi Udobi
To review the entity "black esophagus" and sequela of a slipped laparoscopic adjustable band. The patient's history, physical examination, imaging, and endoscopic findings were reviewed. Detailed review of pathophysiology, presentation, diagnosis, management, and natural history was conducted. "Black esophagus," also known as acute esophageal necrosis (AEN), is a rare condition resulting in black discoloration of the mid to distal esophagus with less than a hundred reported cases. It has not been previously documented in bariatric surgery or following laparoscopic adjustable gastric banding...
June 15, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29905825/targeting-the-incretin-glucagon-system-with-triagonists-to-treat-diabetes
#16
Megan E Capozzi, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Jonathan E Campbell
Glucagon-like peptide-1 (GLP-1) receptor agonists have been efficacious for the treatment of type 2 diabetes due to their ability to reduce weight and attenuate hyperglycemia. However, the activity of GLP-1R-directed strategies is sub-maximal, and the only potent, sustainable treatment for metabolic dysfunction is bariatric surgery, necessitating the development of novel therapeutics. GLP-1 is structurally related to glucagon and glucose-dependent insulinotropic peptide (GIP), allowing for the development of intermixed, unimolecular peptides with activity at each of their respective receptors...
June 13, 2018: Endocrine Reviews
https://www.readbyqxmd.com/read/29904577/surgical-treatment-of-obesity
#17
REVIEW
Vance L Albaugh, Naji N Abumrad
Obesity prevalence continues to increase worldwide, as do the numerous chronic diseases associated with obesity, including diabetes, non-alcoholic fatty liver disease, dyslipidemia, and hypertension. The prevalence of bariatric surgery also continues to increase and remains the most effective and sustainable treatment for obesity. Over the last several years, numerous prospective and longitudinal studies have demonstrated the benefits of bariatric surgery on weight loss, mortality, and other chronic diseases...
2018: F1000Research
https://www.readbyqxmd.com/read/29903686/do-specialized-bariatric-multivitamins-lower-deficiencies-after-rygb
#18
Wendy Schijns, Lisanne T Schuurman, Alida Melse-Boonstra, Cees J H M van Laarhoven, Frits J Berends, Edo O Aarts
BACKGROUND: One of the side effects of bariatric surgery is the risk of vitamin and mineral deficiencies. Vitamin B12, vitamin D, folate, and iron deficiencies are especially common among Roux-en-Y gastric bypass patients. OBJECTIVE: To examine the effectiveness of a specialized multivitamin supplement for Roux-en-Y gastric bypass patients on deficiencies the first 3 years postoperatively, retrospectively in a large, prospectively collected cohort. SETTING: Large specialized bariatric hospital...
April 3, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29902703/metabolic-liver-inflammation-in-obesity-does-not-robustly-decrease-hepatic-and-circulating-cetp
#19
Lisanne L Blauw, Zhuang Li, Sander S Rensen, Jan Willem M Greve, Aswin Verhoeven, Rico J Derks, Martin Giera, Yanan Wang, Patrick C N Rensen
BACKGROUND AND AIMS: We recently showed that plasma cholesteryl ester transfer protein (CETP) is mainly derived from VSIG4-positive Kupffer cells. Activation of these cells by the bacterial endotoxin lipopolysaccharide (LPS) strongly decreases CETP expression. As Kupffer cell activation plays a detrimental role in the progression of non-alcoholic fatty liver disease (NAFLD), we aimed to study if metabolic liver inflammation is also associated with a decrease in hepatic and circulating CETP...
June 7, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29901782/bariatric-surgery-does-not-appear-to-affect-women-s-breast-milk-composition
#20
Goele Jans, Roland Devlieger, Vicky De Preter, Lieveke Ameye, Kristien Roelens, Matthias Lannoo, Bart Van der Schueren, Johan Verhaeghe, Christophe Matthys
Background: The breast-milk composition in the first 6 wk postpartum of women who have undergone bariatric surgery (BS) is unknown. Objective: The aim of this study was to examine 1) the breast-milk macronutrient and vitamin A composition in women who had and who had not undergone BS and 2) the impact of maternal diet on the breast-milk composition. We hypothesized that the milk of women who had undergone BS would be less energy dense and have a lower vitamin A concentration than that of other women...
June 13, 2018: Journal of Nutrition
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