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https://www.readbyqxmd.com/read/28922016/high-degree-of-variability-in-reporting-of-clinical-and-patient-reported-outcomes-after-hip-arthroscopy
#1
Austin V Stone, Cale A Jacobs, T David Luo, Molly C Meadows, Shane J Nho, Allston J Stubbs, Eric C Makhni
BACKGROUND: Hip arthroscopy for the treatment of intra-articular pathology is a rapidly expanding field. Outcome measures should be reported to document the efficacy of arthroscopic procedures; however, the most effective outcome measures are not established. PURPOSE: To evaluate the variability in outcomes reported after hip arthroscopy and to compare the responsiveness of patient-reported outcome (PRO) instruments. STUDY DESIGN: Systematic review...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28921474/origins-of-phantom-limb-pain
#2
Damien P Kuffler
Phantom limb pain (PLP) is a chronic neuropathic pain occurring in 45-85% of patients who undergo major amputations of the upper and lower extremities. Chronic pain is physically and mentally debilitating, affecting an individual's potential for self-care and the performance of daily living activities essential for personal and economic independence. In addition, chronic pain may lead to depression and feelings of hopelessness. A National Center for Biotechnology Information study found that in the USA alone, the annual cost of dealing with neuropathic pain is more than $600 billion, with an estimated 20 million people in the USA suffering this condition...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28921038/efficacy-and-safety-of-tacrolimus-for-myasthenia-gravis-a-systematic-review-and-meta-analysis
#3
REVIEW
Liang Wang, Suxian Zhang, Jianying Xi, Wenhui Li, Lei Zhou, Jun Lu, Jiahong Lu, Tiansong Zhang, Chongbo Zhao
To evaluate the efficacy and safety of tacrolimus in patients with myasthenia gravis (MG), a systematic review and meta-analysis was performed. We searched PubMed and Embase for randomized controlled trials and clinical controlled trials in English language. Demographic and clinical characteristics of the MG patients were extracted. Differences in the current glucocorticoids (GC) dose in each included study were the primary outcome measure. The adverse events reported in each included study were used as safety evaluation...
September 18, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28920890/exercise-in-patients-with-multiple-sclerosis
#4
REVIEW
Robert W Motl, Brian M Sandroff, Gert Kwakkel, Ulrik Dalgas, Anthony Feinstein, Christoph Heesen, Peter Feys, Alan J Thompson
Exercise can be a beneficial rehabilitation strategy for people with multiple sclerosis to manage symptoms, restore function, optimise quality of life, promote wellness, and boost participation in activities of daily living. However, this population typically engages in low levels of health-promoting physical activity compared with adults from the general population, a fact which has not changed in the past 25 years despite growing evidence of the benefits of exercise. To overcome this challenge, the main limitations to promoting exercise through the patient-clinician interaction must be addressed...
October 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28920550/sit-to-stand-activity-during-stroke-rehabilitation
#5
Andy Kerr, Jesse Dawson, Chris Robertson, Philip Rowe, Terence J Quinn
Objectives The sit to stand (STS) movement is key to independence and commonly affected by stroke. Repetitive practice is likely to improve STS ability during rehabilitation, however current practice levels are unknown. The objective of this study was simply to count the number of STS movements performed during the rehabilitation period of stroke patients using a physical activity monitor (PAM) and test whether being observed altered outcome. Methods Participants were medically stable patients referred for rehabilitation following stroke...
September 18, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28919728/chronic-obstructive-pulmonary-disease-with-mild-airflow-limitation-current-knowledge-and-proposal-for-future-research-a-consensus-document-from-six-scientific-societies
#6
REVIEW
Andrea Rossi, Bojana Butorac-Petanjek, Marco Chilosi, Borja G Cosío, Matjaz Flezar, Nikolaos Koulouris, José Marin, Neven Miculinic, Guido Polese, Miroslav Samaržija, Sabina Skrgat, Theodoros Vassilakopoulos, Andrea Vukić-Dugac, Spyridon Zakynthinos, Marc Miravitlles
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and morbidity worldwide, with high and growing prevalence. Its underdiagnosis and hence under-treatment is a general feature across all countries. This is particularly true for the mild or early stages of the disease, when symptoms do not yet interfere with daily living activities and both patients and doctors are likely to underestimate the presence of the disease. A diagnosis of COPD requires spirometry in subjects with a history of exposure to known risk factors and symptoms...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28919664/developmental-coordination-disorders-and-sensory-processing-and-integration-incidence-associations-and-co-morbidities
#7
Susan Allen, Jackie Casey
INTRODUCTION: Children with developmental coordination disorder or sensory processing and integration difficulties face challenges to participation in daily living. To date there has been no exploration of the co-occurrence of developmental coordination disorders and sensory processing and integration difficulties. METHOD: Records of children meeting Diagnostic and Statistical Manual - V criteria for developmental coordination disorder (n = 93) age 5 to 12 years were examined...
September 2017: British Journal of Occupational Therapy
https://www.readbyqxmd.com/read/28919325/the-influence-of-lifestyle-on-airborne-particle-surface-area-doses-received-by-different-western-populations
#8
A Pacitto, L Stabile, T Moreno, P Kumar, A Wierzbicka, L Morawska, G Buonanno
In the present study, the daily dose in terms of particle surface area received by citizens living in five cities in Western countries, characterized by different lifestyle, culture, climate and built-up environment, was evaluated and compared. For this purpose, the exposure to sub-micron particle concentration levels of the population living in Barcelona (Spain), Cassino (Italy), Guilford (United Kingdom), Lund (Sweden), and Brisbane (Australia) was measured through a direct exposure assessment approach. In particular, measurements of the exposure at a personal scale were performed by volunteers (15 per each population) that used a personal particle counter for different days in order to obtain exposure data in microenvironments/activities they resided/performed...
September 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28918654/stakeholders-perceptions-sought-to-inform-the-development-of-a-low-cost-mobile-robot-for-older-adults-a-qualitative-descriptive-study
#9
Justine S Sefcik, Michelle J Johnson, Mark Yim, Tessa Lau, Nicholas Vivio, Caio Mucchiani, Pamela Z Cacchione
Creative solutions are needed to support community-dwelling older adults residing in a variety of settings including their house, apartment, or Supportive Apartment Living (SAL) to promote independence and reduce the risk of nursing home replacement. The objective of this study was to gain an understanding of older adults' needs for physical, mental, and social activities to support the design and functionality of a low-cost mobile assistive robot. A qualitative descriptive study was designed which included three stakeholder focus groups (caregivers, clinicians, and older adults)...
September 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28918171/the-association-between-delirium-and-sarcopenia-in-older-adult-patients-admitted-to-acute-geriatrics-units-results-from-the-glisten-multicenter-observational-study
#10
Giuseppe Bellelli, Antonella Zambon, Stefano Volpato, Pasquale Abete, Lara Bianchi, Mario Bo, Antonio Cherubini, Francesco Corica, Mauro Di Bari, Marcello Maggio, Giovanna Maria Manca, Maria Rosaria Rizzo, Andrea Rossi, Francesco Landi
BACKGROUND & AIMS: To date, studies assessing the relationship between sarcopenia and delirium, two of the most common geriatric syndromes, are lacking. We sought to explore this association by investigating the co-occurrence of these two conditions and the independent association between them in a population of hospitalized older adults. METHODS: Cross-sectional multicenter analysis of older adults consecutively admitted to 12 acute geriatric units (AGUs). Sarcopenia was assessed upon admission by evaluating the presence of low skeletal mass index (kg/m(2)), and either low handgrip strength or low walking speed (European Working Group on Sarcopenia in Older People, EWGSOP criteria)...
September 5, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28918118/case-report-aquatic-therapy-and-end-stage-dementia
#11
Bruce E Becker, Stacy Lynch
A 54-year old female, retired due to progressive cognitive decline, was diagnosed with early-onset Alzheimer's dementia. Conventional medication therapy for dementia had proven futile. Initial evaluation revealed a non-verbal female seated in a wheelchair, dependent on 2-person assist for all transfers and activities of daily living (ADLs.) She had been either non-responsive or actively resistive for both ADLs and transfers in the 6 months prior to assessment. Following a total of 17 one hour therapy sessions over 19 weeks in a warm water therapy pool, she achieved ability to tread water for 15 minutes, transfers improved to moderate to-maximum assist from seated, ambulation improved to 1000' with minimum-to-moderate assist of 2 persons...
September 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28916991/higher-physical-activity-and-lower-pain-levels-before-surgery-predict-non-improvement-of-knee-pain-1%C3%A2-year-after-tka
#12
Nikolai Kornilov, Maren Falch Lindberg, Caryl Gay, Alexander Saraev, Taras Kuliaba, Leiv Arne Rosseland, Anners Lerdal
PURPOSE: The purpose of this study was to describe patterns of pain during the first year following total knee arthroplasty (TKA) and evaluate pre- and postoperative factors associated with pain and patient satisfaction at 1 year. It was hypothesized that more severe preoperative pain would be associated with more residual pain and lower patient satisfaction 1 year after surgery. METHODS: A longitudinal cohort study was performed with repeated measures of pain (0-10 numeric rating scale) and evaluation of other self-reported symptoms (Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, and Fatigue Severity Score), daily functioning (Lawton Instrumental Activities of Daily Living Scale), quality of life (EQ-5D-3L), knee function (KSS Knee and Function Score), perioperative and clinical characteristics (e...
September 15, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28915930/predicting-activities-of-daily-living-for-cancer-patients-using-an-ontology-guided-machine-learning-methodology
#13
Hua Min, Hedyeh Mobahi, Katherine Irvin, Sanja Avramovic, Janusz Wojtusiak
BACKGROUND: Bio-ontologies are becoming increasingly important in knowledge representation and in the machine learning (ML) fields. This paper presents a ML approach that incorporates bio-ontologies and its application to the SEER-MHOS dataset to discover patterns of patient characteristics that impact the ability to perform activities of daily living (ADLs). Bio-ontologies are used to provide computable knowledge for ML methods to "understand" biomedical data. RESULTS: This retrospective study included 723 cancer patients from the SEER-MHOS dataset...
September 16, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28915841/is-there-room-for-resilience-a-scoping-review-and-critique-of-substance-use-literature-and-its-utilization-of-the-concept-of-resilience
#14
REVIEW
Katherine Rudzinski, Peggy McDonough, Rosemary Gartner, Carol Strike
Research in the area of illicit substance use remains preoccupied with describing and analyzing the risks of people who use drugs (PWUD), however more recently there has been a drive to use a strengths-based or resilience approach as an alternative to investigating drug use. This leads us to ask: what can be known about PWUD from the point of view of resilience? The objective of this scoping review is to analyze how the concept of resilience is defined, operationalized, and applied in substance use research...
September 15, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/28914424/new-perspectives-in-nanotherapeutics-for-chronic-respiratory-diseases
#15
Adriana Lopes da Silva, Fernanda Ferreira Cruz, Patricia Rieken Macedo Roccco, Marcelo Marcos Morales
According to the World Health Organization (WHO), hundreds of millions of people of all ages and in all countries suffer from chronic respiratory diseases, with particular negative consequences such as poor health-related quality of life, impaired work productivity, and limitations in the activities of daily living. Chronic obstructive pulmonary disease, asthma, occupational lung diseases (such as silicosis), cystic fibrosis, and pulmonary arterial hypertension are the most common of these diseases, and none of them are curable with current therapies...
September 15, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/28914352/impact-of-physical-activity-on-reporting-of-childhood-asthma-symptoms
#16
Benedicta Nneoma Nnodum, Meredith C McCormack, Nirupama Putcha, Seungyoung Hwang, Laura M Paulin, Emily P Brigham, Ashraf Fawzy, Karina Romero, Gregory B Diette, Nadia N Hansel
This study aims to determine the impact of physical activity on asthma symptom reporting among children living in an inner city. Among 147 children aged 5-12 years with physician-diagnosed asthma, we assessed asthma symptoms using twice-daily diaries and physical activity using the physical activity questionnaire for children during three 8-day periods (baseline, 3 and 6 months). Linear, logistic, and quasi-poisson regression models were used to determine the association between physical activity and asthma symptoms; adjusting for age, sex, race, BMI, caregiver's education, asthma severity, medication use, and season...
September 15, 2017: Lung
https://www.readbyqxmd.com/read/28914139/the-influence-of-geometric-design-variables-on-the-kinematic-performance-of-a-surface-guided-total-knee-replacement
#17
Shabnam Pejhan, Eric Bohm, Jan-Mels Brandt, Urs Wyss
OBJECTIVE: Tibiofemoral geometries in a total knee replacement (TKR) affect the performance of an implant during activities of daily living. The specially shaped components of a surface-guided TKR aim to control the tibiofemoral motion, such that a normal pattern of motion is achieved, even at high flexion angles. The purpose of this study was to assess the influence of the design parameters on the kinematic behavior of such an implant. A combination of design variables was determined that resulted in the least deviation from the design kinematic target...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28914085/development-of-a-patient-centered-conceptual-model-of-the-impact-of-living-with-autism-spectrum-disorder
#18
Fiona McDougall, Thomas Willgoss, Steve Hwang, Federico Bolognani, Lorraine Murtagh, Evdokia Anagnostou, Diana Rofail
The aim of this study was to generate a patient-centered conceptual model of the impact of living with autism spectrum disorder, which can be used to support the selection of outcome measures for clinical trials. Following an initial literature review to identify preliminary concepts and inform an interview guide, in-depth face-to-face interviews were conducted with adolescents and adults with autism spectrum disorder (IQ ⩾ 70) (n = 10), as well as parents of children, adolescents, and adults with autism spectrum disorder (IQ ⩾ 70) (n = 26)...
September 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28913998/depressive-symptoms-and-quality-of-life-in-age-related-macular-degeneration-based-on-korea-national-health-and-nutrition-examination-survey-knhanes
#19
So Jung Ryu, Won June Lee, Leslie Bishop Tarver, Yong Un Shin, Min Ho Kang, Mincheol Seong, Hee Yoon Cho
PURPOSE: This study was conducted to investigate the depressive symptoms and quality of life (QOL) in patients with age-related macular degeneration (AMD) using data obtained from the Korea National Health and Nutritional Examination Survey V-2 (KNHANES V-2) conducted in 2011. METHODS: This was a population-based, cross-sectional study that selected 329 participants from the fifth KNHANES (2011) who were diagnosed with AMD by an ophthalmologist based on fundus photography...
August 18, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28912713/meta-analysis-for-clinical-evaluation-of-xingnaojing-injection-for-the-treatment-of-cerebral-infarction
#20
REVIEW
Xiao Ma, Yu X Yang, Nian Chen, Qian Xie, Tao Wang, Xuan He, Jian Wang
Objective: Xingnaojing injection (XNJ) is derived from An-Gong-Niu-Huang pill, a well-known traditional Chinese patent medicine, which is widely used for stroke. To evaluate the therapeutic effect of XNJ on cerebral infarction, an extensive meta-analysis was used. Methods: Six major electronic databases including the Chinese Biomedical Database (CBM), Wanfang, the VIP medicine information system (VMIS) and the China National Knowledge Infrastructure (CNKI), PubMed, Embase, and the Cochrane Library were examined to retrieve randomized controlled trials designed to evaluate the clinical efficacy of XNJ in treating CI before November 26, 2016...
2017: Frontiers in Pharmacology
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