keyword
MENU ▼
Read by QxMD icon Read
search

alopecia universalis

keyword
https://www.readbyqxmd.com/read/29200765/simvastatin-ezetimibe-therapy-for-recalcitrant-alopecia-areata-an-open-prospective-study-of-14-patients
#1
Joong-Woon Choi, Dong-Woo Suh, Bark-Lynn Lew, Woo-Young Sim
Background: Simvastatin belongs to the statin family, whose members have immunomodulatory activities. Ezetimibe have synergetic effects when co-administered with simvastatin. In several case reports, alopecia totalis and alopecia universalis were successfully treated with simvastatin/ezetimibe, suggesting that this combination could be a new efficient therapy for recalcitrant alopecia areata (AA). Objective: To verify the efficacy of the simvastatin/ezetimibe combination therapy for recalcitrant AA and investigate the relationship between various treatment responses and prognostic factors...
December 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/29163335/alopecia-universalis-following-alemtuzumab-treatment-in-multiple-sclerosis-a-barely-recognized-manifestation-of-secondary-autoimmunity-report-of-a-case-and-review-of-the-literature
#2
Julian Zimmermann, Timo Buhl, Marcus Müller
Secondary autoimmunity is the most frequent adverse event occurring in almost every other alemtuzumab-treated multiple sclerosis patient. We report a case of a patient with relapsing-remitting multiple sclerosis who reported smooth, circular areas of complete hair loss on both thighs 6 months after the second treatment cycle with alemtuzumab. The patient was diagnosed as having alopecia areata (AA). Within 3 months, AA progressed to complete loss of all body hair (alopecia universalis). Current literature rarely connects alemtuzumab with the onset of alopecia of autoimmune origin...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29150291/ruxolitinib-conjugated-gold-nanoparticles-for-topical-administration-an-alternative-for-treating-alopecia
#3
Sanda Boca, Cristian Berce, Ancuta Jurj, Bobe Petrushev, Laura Pop, Grigore-Aristide Gafencu, Sonia Selicean, Vlad Moisoiu, Daiana Temian, Wilhelm-Thomas Micu, Simion Astilean, Cornelia Braicu, Ciprian Tomuleasa, Ioana Berindan-Neagoe
Alopecia is a dermatological condition for which Janus kinase (JAK) inhibitors have recently emerged as potential therapy options, but with limited practical use because of the systemic side effects. The topical use of Ruxolitinib in alopecia universalis has been demonstrated, but little is known about the pharmacodynamics and pharmacokinetics of this way of administration. Nanomedicine provides improved therapeutics. In the current paper we present preliminary data regarding the potential use of Ruxolitinib-conjugated gold nanoparticles (GNPs) in dermatological conditions, as GNPs have been proven to have a reduced absorption rate into the systemic blood flow for cutaneous administration...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28973128/screening-guidelines-for-thyroid-function-in-children-with-alopecia-areata
#4
Deepa Patel, Ping Li, Andrew J Bauer, Leslie Castelo-Soccio
Importance: The incidence of thyroid disease in children with alopecia areata (AA) has been widely studied with no consensus on whether a true association with AA exists. In addition, screening practices for thyroid dysfunction in children with AA vary widely among clinicians. Objective: To reduce health care costs, eliminate unnecessary testing, and standardize clinical practices, we sought to to characterize thyroid function in children with AA to establish guidelines for screening...
September 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28940615/satoyoshi-syndrome-a-case-report-from-india
#5
Venkatraman Mani, Renu George
Satoyoshi syndrome was first reported in Japan in 1967. It is a rare multisystem disorder of presumed autoimmune etiology that is characterized by alopecia, intermittent painful muscle spasms, diarrhea, and antinuclear antibody positivity. We report an 11-year-old girl with Satoyoshi syndrome who presented to the dermatology department for treatment of alopecia universalis. We present this case to emphasize the importance of recognizing Satoyoshi syndrome, which could go unnoticed if not suspected.
September 22, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28932754/hair-growth-in-two-alopecia-patients-after-fecal-microbiota-transplant
#6
Dionne Rebello, Elaina Wang, Eugene Yen, Peter A Lio, Colleen R Kelly
Clostridium difficile infections can be life-threatening but are increasingly being treated successfully with fecal microbiota transplantation (FMT). We report two patients with alopecia universalis who developed subsequent hair regrowth after FMT for treatment of recurrent C. difficile infections. Gut microbiota may have immunomodulatory effects in autoimmune conditions such as alopecia areata, and further study may elucidate disease mechanisms and lead to alternative treatment options for these patients for whom treatment options are currently limited...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28879192/unsuccessful-treatment-of-alopecia-areata-with-simvastatin-ezetimibe-experience-in-12-patients
#7
Mabe Freitas Gouveia, Ralph M Trüeb
BACKGROUND/AIMS: Alopecia areata is a common immune-mediated hair condition with limited treatment options and success rates. There is evidence that statins, which are used for reducing atherogenesis and cardiovascular disease, have immunomodulatory activities and therefore may also be used for treatment of selected dermatologic conditions, including alopecia areata. Among treatments evaluated for alopecia areata, oral simvastatin/ezetimibe therapy is currently under the scrutiny of expert opinion...
August 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28839389/rare-presentation-of-alopecia-universalis-congenita-and-twenty-nail-dystrophy-in-siblings
#8
Debdeep Mitra, Reetu Agarwal, Ajay Chopra, Renu Kandpal
Congenital alopecia universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive ridging and nail plate roughness leading to unsightly lustureless nails. We report a rare case of two siblings with alopecia universalis congenita with twenty-nail dystrophy...
April 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28827491/pyridostigmine-induced-bradycardia-in-patient-with-musk-ab-positive-myasthenia-gravis-and-alopecia-universalis
#9
Ferdos Nazari, Siamak Abdi
No abstract text is available yet for this article.
September 2017: Journal of Clinical Neuromuscular Disease
https://www.readbyqxmd.com/read/28755063/brazilian-experience-of-the-treatment-of-alopecia-universalis-with-the-novel-antirheumatic-therapy-tofacitinib-a-case-series
#10
Morton Scheinberg, Regina Adalva de Lucena Couto Océa, Boris Afonso Cruz, Sineida Berbert Ferreira
INTRODUCTION: Alopecia universalis is an autoimmune disorder for which there is no known effective therapy. Tofacitinib-a novel antirheumatic therapy for rheumatoid arthritis-has been shown in some reports to induce sustained hair growth in patients with alopecia universalis. CASE SERIES: Here, we review the experiences of four different rheumatologists across the country regarding four Brazilian patients with alopecia universalis who were treated with tofacitinib ...
December 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28705291/lichenoid-dermatitis-in-an-adult-with-immune-dysregulation-polyendocrinopathy-enteropathy-x-linked-ipex-syndrome
#11
Young M Choi, Yen T Wang, Bob Geng, Maria Garcia-Lloret, Chandra N Smart
A 23-year-old man presented to our practice with erythroderma and an unusual retiform eruption, along with alopecia universalis and nail dystrophy. He had had no skin findings at birth, but since early infancy had had localized eczematous eruptions of his skin. At 10 years of age, he had developed a generalized eczematous flare requiring hospitalization, and another generalized episode occurred in October 2010. He was prescribed prednisone 60 mg daily, which initially provided an improvement, but tapering of the corticosteroid resulted in another generalized flare...
2017: Skinmed
https://www.readbyqxmd.com/read/28704810/long-term-prognosis-of-alopecia-totalis-and-alopecia-universalis-a-longitudinal-study-with-more-than-10-years-of-follow-up-better-than-reported
#12
Yong Hyun Jang, Nam-Soo Hong, Sun Young Moon, Dong Hyuk Eun, Won Kee Lee, Seong Geun Chi, Jun Young Kim, Weon Ju Lee, Seok-Jong Lee, Do Won Kim
BACKGROUND: In alopecia totalis (AT) and alopecia universalis (AU), the chance of full hair regrowth is known to be less than 10%. However, this information is based on a few older studies conducted in the 1950s and 1960s. OBJECTIVE: We investigated the current long-term prognosis of individuals with AT/AU. METHODS: A retrospective chart review was performed in patients with AT/AU between 1994 and 2005. Outcome data were collected by reviewing outpatient clinical files or by phone interviews...
2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28635319/a-case-of-topical-ruxolitinib-treatment-failure-in-alopecia-areata
#13
Maya Deeb, Renée A Beach
Alopecia areata (AA) is an autoimmune-mediated, nonscarring form of hair loss. Despite its prevalence, current management options are limited, especially when the disease has progressed to alopecia totalis (AT) or alopecia universalis (AU). Recent evidence that janus kinase (JAK) signaling contributes to AA pathogenesis prompted the investigation of JAK inhibitors such as tofacitinib and ruxolitinib as possible oral treatments. However, the potential for significant adverse effects with systemic JAK inhibition makes local administration a more attractive option...
November 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28632888/excellent-response-to-tofacitinib-treatment-in-a-patient-with-alopecia-universalis
#14
Funda Erduran, Esra Adışen, Ahmet Burhan Aksakal
Alopecia universalis (AU) is generally considered a variant of alopecia areata (AA), in which the treatment options seldom provide satisfactory results. However, successful treatment of several cases of AA and its variants with oral Janus kinase (JAK) inhibitors have been reported recently. Here we report a 23-year-old female patient with AU successfully treated with tofacitinib, a selective JAK-3 inhibitor. The initial tofacitinib dose was 5 mg twice daily. After 2 months of treatment, partial hair regrowth was seen on the scalp and eyebrows...
June 2017: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/28627278/methotrexate-for-the-treatment-of-pediatric-alopecia-areata
#15
Erin T Landis, Rita O Pichardo-Geisinger
PURPOSE: Alopecia areata is a form of nonscarring hair loss that occurs in pediatric and adult patients, with presentation varying from round or ovoid patches of alopecia to alopecia totalis or universalis. While frustrating for patients, it can also be frustrating for clinicians to treat, as there is no definitive treatment. Dermatologists are very familiar with the use of methotrexate for psoriasis and other inflammatory skin diseases, and this medication is generally well tolerated in children...
June 30, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28536724/successful-hair-regrowth-in-a-korean-patient-with-alopecia-universalis-following-tofacitinib-treatment
#16
Bo Young Kim, Hyun-Sook Kim
No abstract text is available yet for this article.
May 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28515996/dermoscopy-of-alopecia-areata-a-retrospective-analysis
#17
Abhijeet K Jha, Uday K Udayan, P K Roy, Amar K J Amar, R K P Chaudhary
BACKGROUND: Dermoscopy devices can overcome the refractive properties of stratum corneum by interface medium or cross polarization such that the lesion can be easily seen. AIM: To examine the dermoscopic feature in alopecia areata and correlate the severity of disease with dermoscopic features. MATERIALS AND METHODS: Retrospective analysis of 72 patients suffering from alopecia areata (AA), irrespective of age and sex, who visited the dermatology outpatient department of a tertiary care center in Eastern India was carried out...
April 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28492603/recovery-of-hair-in-the-psoriatic-plaques-of-a-patient-with-coexistent-alopecia-universalis
#18
Christine Anastasiou, Carolyn Goh, Vanessa Holland
No abstract text is available yet for this article.
April 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28378336/review-of-treatment-for-alopecia-totalis-and-alopecia-universalis
#19
REVIEW
Sama Kassira, Dorota Z Korta, Lance W Chapman, Francis Dann
Alopecia areata (AA) is an autoimmune disease directed at the hair follicle. Although usually limited to patchy hair loss over the scalp (focalis), AA can present as total loss of scalp hair (totalis; AT) or as total loss of both scalp and body hair (universalis; AU). Management of AT and AU can be challenging, and although multiple treatment modalities have been explored, no therapy is currently FDA-approved. This review focuses on the evidence for current treatment options for AT and AU. The PubMed database was searched from January 1, 2000, to September 1, 2016, for clinical trials, retrospective studies, and case reports of treatments for AT and AU...
August 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28349112/treatment-of-alopecia-universalis-with-oral-alitretinoin-a-case-report
#20
Pierre-Olivier Grenier, Hélène Veillette
No abstract text is available yet for this article.
March 2017: JAAD Case Reports
keyword
keyword
93734
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"