keyword
MENU ▼
Read by QxMD icon Read
search

Risks for CAP

keyword
https://www.readbyqxmd.com/read/28551746/occurrence-removal-and-risk-assessment-of-antibiotics-in-12-wastewater-treatment-plants-from-dalian-china
#1
Xin Zhang, Hongxia Zhao, Juan Du, Yixuan Qu, Chen Shen, Feng Tan, Jingwen Chen, Xie Quan
In this study, the occurrence and removal efficiencies of 31 antibiotics, including 11 sulfonamides (SAs), five fluoroquinolones (FQs), four macrolides (MLs), four tetracyclines (TCs), three chloramphenicols (CAPs), and four other antibiotics (Others), were investigated in 12 municipal wastewater treatment plants (WWTPs) in Dalian, China. A total of 29 antibiotics were detected in wastewater samples with the concentration ranging from 63.6 to 5404.6 ng/L. FQs and SAs were the most abundant antibiotic classes in most wastewater samples, accounting for 42...
May 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28544534/time-to-event-analysis-of-polatuzumab-vedotin-induced-peripheral-neuropathy-to-assist-in-the-comparison-of-clinical-dosing-regimens
#2
D Lu, W R Gillespie, S Girish, P Agarwal, C Li, J Hirata, Y-W Chu, M Kagedal, L Leon, V Maiya, J Y Jin
Polatuzumab vedotin, an antibody-drug conjugate containing monomethyl auristatin E, was associated with an incidence of grade ≥2 peripheral neuropathy (PN) of 55-72% in patients with indolent non-Hodgkin lymphoma in a phase II study, when dosed 1.8-2.4 mg/kg every 3 weeks until progression or for a maximum of 17 cycles. To quantify the correlation of conjugate exposure and treatment duration with PN risk, a time-to-event model was developed using data from phase I and II studies. The model suggested that PN risk increased with conjugate exposure and treatment cycles, and a trend for increased risk with body weight and albumin concentration...
May 23, 2017: CPT: Pharmacometrics & Systems Pharmacology
https://www.readbyqxmd.com/read/28542347/effectiveness-of-pneumococcal-vaccines-in-preventing-pneumonia-in-adults-a-systematic-review-and-meta-analyses-of-observational-studies
#3
Myint Tin Tin Htar, Anke L Stuurman, Germano Ferreira, Cristiano Alicino, Kaatje Bollaerts, Chiara Paganino, Ralf René Reinert, Heinz-Josef Schmitt, Cecilia Trucchi, Thomas Vestraeten, Filippo Ansaldi
INTRODUCTION: S. pneumoniae can cause a wide spectrum of diseases, including invasive pneumococcal disease and pneumonia. Two types of pneumococcal vaccines are indicated for use in adults: 23-valent pneumococcal polysaccharide vaccines (PPV23) and a 13-valent pneumococcal conjugate vaccine (PCV13). OBJECTIVE: To systematically review the literature assessing pneumococcal vaccine effectiveness (VE) against community-acquired pneumonia (CAP) in adults among the general population, the immunocompromised and subjects with underlying risk factors in real-world settings...
2017: PloS One
https://www.readbyqxmd.com/read/28532926/sequential-segmental-terminal-lenticular-side-cut-dissection-for-safe-and-effective-small-incision-lenticule-extraction-in-thin-lenticules
#4
Soosan Jacob, Amar Agarwal, Cosimo Mazzotta, Athiya Agarwal, John Michael Raj
Small-incision lenticule extraction may be associated with complications such as partial lenticular dissection, torn lenticule, lenticular adherence to cap, torn cap, and sub-cap epithelial ingrowth, some of which are more likely to occur during low-myopia corrections. We describe sequential segmental terminal lenticular side-cut dissection to facilitate minimally traumatic and smooth lenticular extraction. Anterior lamellar dissection is followed by central posterior lamellar dissection, leaving a thin peripheral rim and avoiding the lenticular side cut...
April 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28528893/body-temperature-responses-to-handling-stress-in-wintering-black-capped-chickadees-poecile-atricapillus-l
#5
Agnès Lewden, Andreas Nord, Magali Petit, François Vézina
Body temperature variation in response to acute stress is typically characterized by peripheral vasoconstriction and a concomitant increase in core body temperature (stress-induced hyperthermia). It is poorly understood how this response differs between species and within individuals of the same species, and how it is affected by the environment. We therefore investigated stress-induced body temperature changes in a non-model species, the Black-capped Chickadee, in two environmental conditions: outdoors in low ambient temperature (mean: -6...
May 19, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28527666/hepatic-steatosis-progresses-faster-in-hiv-mono-infected-than-hiv-hcv-co-infected-patients-and-is-associated-with-liver-fibrosis
#6
Thomas Pembroke, Marc Deschenes, Bertrand Lebouché, Amine Benmassaoud, Maida Sewitch, Peter Ghali, Philip Wong, Alex Halme, Elise Vuille-Lessard, Costa Pexos, Marina B Klein, Giada Sebastiani
BACKGROUND & AIMS: Hepatic steatosis (HS) seems common in patients infected with human immunodeficiency virus (HIV). However, the relative effect of HIV, as well as hepatitis C virus (HCV) in those co-infected, and the influence of HS on liver fibrosis progression are unclear. METHODS: The LIVEr disease in HIV (LIVEHIV) is a Canadian prospective Cohort using transient elastography and associated controlled attenuation parameter (CAP) to screen for HS and liver fibrosis in unselected HIV-infected adults...
May 17, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28521774/correlation-of-cell-free-dna-plasma-concentration-with-severity-of-non-alcoholic-fatty-liver-disease
#7
Thomas Karlas, Lara Weise, Stephanie Kuhn, Felix Krenzien, Matthias Mehdorn, David Petroff, Nicolas Linder, Alexander Schaudinn, Harald Busse, Volker Keim, Johann Pratschke, Johannes Wiegand, Katrin Splith, Moritz Schmelzle
BACKGROUND: The assessment of fibrosis and inflammatory activity is essential to identify patients with non-alcoholic fatty liver disease (NAFLD) at risk for progressive disease. Serum markers and ultrasound-based methods can replace liver biopsy for fibrosis staging, whereas non-invasive characterization of inflammatory activity remains a clinical challenge. Cell-free DNA (cfDNA) is a novel non-invasive biomarker for assessing cellular inflammation and cell death, which has not been evaluated in NAFLD...
May 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28508246/the-significance-of-histological-analysis-following-laser-transurethral-resection-of-the-prostate
#8
Shady Nafie, John Dormer, Masood A Khan
PURPOSE: Monopolar transurethral resection of the prostate is the gold standard for the treatment of benign prostatic hyperplasia. However, due to the associated risks of bleeding and TUR syndrome, laser prostate surgery is gaining popularity. We perform thulium-laser vaporesection of the prostate (TmLRP), where histological samples are generated in every case. We determined postoperative incidence and significance of prostate cancer detection, by retrospective histological examination of our cases...
May 15, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28501668/response-adjusted-for-days-of-antibiotic-risk-radar-evaluation-of-a-novel-method-to-compare-strategies-to-optimise-antibiotic-use
#9
Valentijn A Schweitzer, Maarten van Smeden, Douwe F Postma, Jan Jelrik Oosterheert, Marc J M Bonten, Cornelis H van Werkhoven
OBJECTIVES: The Response Adjusted for Days of Antibiotic Risk (RADAR)-statistic was proposed to improve efficiency of trials comparing antibiotic stewardship strategies to optimize antibiotic use. We studied the behaviour of RADAR in a non-inferiority trial in which a beta-lactam monotherapy strategy (BL, n=656) was non-inferior to fluoroquinolone monotherapy (FQL, n=888) for moderately-severe community-acquired pneumonia (CAP) patients. METHODS: Patients were ranked according to clinical outcome, using five or eight categories, and antibiotic use...
May 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28500489/population-based-study-of-grade-progression-in-patients-who-harboured-gleason-3%C3%A2-%C3%A2-3
#10
Fanny Sampurno, Arul Earnest, Jeremy Millar, Mark Frydenberg, Declan Murphy, Warwick Delprado, Sue Evans
PURPOSE: This study aimed to evaluate (1) the time interval between a decision to commence on active surveillance (AS) and grade progression in community practice; (2) factors predicting grade progression in localised prostate cancer (CaP) patients apparently undergoing AS. METHODS: Data from the Prostate Cancer Outcomes Registry-Victoria were used to analyze men with Gleason 3 + 3 CaP or less who had at least one repeat biopsy. Unadjusted and adjusted 5-year Kaplan-Meier survival curves were used to assess the time to grade progression...
May 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28492131/personal-protective-equipment-in-animal-research
#11
Jason S Villano, Janet M Follo, Mark G Chappell, Morris T Collins
The occupational health and safety program is an integral component of a comprehensive animal care and use program. Itisimportant to mitigate the risk of exposures of animal care and research personnel to allergens and physical, chemical, radiologic,and biologic hazards during the conduct of various tasks. This need is especially true in infectious disease and biocontainment research. One aspect of the program is the provision of personal protective equipment (PPE). Commercially available PPE should be carefully evaluated based on their material composition and performance according to manufacturer data...
May 10, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28489751/polyp-missing-rate-and-its-associated-risk-factors-of-referring-hospitals-for-endoscopic-resection-of-advanced-colorectal-neoplasia
#12
Jae Gyu Shin, Hyung Wook Kim, Su Bum Park, Cheol Woong Choi, Dae Hwan Kang, Su Jin Kim, Hyeong Seok Nam, Dae Gon Ryu
Missed polyps are frequently observed in surveillance colonoscopy or referral resection. We evaluated the polyp missing rate and its associated risk factors in patients who were referred to a tertiary hospital for endoscopic resection of advanced colorectal neoplasia.A total of 388 patients with advanced neoplasia who underwent colonoscopy in their referring hospitals and only endoscopic resection without total colonoscopy in Pusan National University Yangsan Hospital from 2009 to 2014 and who underwent surveillance colonoscopy within 6 to 12 months were retrospectively analyzed...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28483678/inequity-in-organ-allocation-for-patients-awaiting-liver-transplantation-rationale-for-uncapping-the-model-for-end-stage-liver-disease
#13
Mitra K Nadim, Joseph DiNorcia, Lingyun Ji, Susan Groshen, Josh Levitsky, Randall S Sung, W Ray Kim, Kenneth Andreoni, David Mulligan, Yuri S Genyk
BACKGROUND: The goal of organ allocation is to distribute a scarce resource equitably to the sickest patients. In the United States, the Model for End-stage Liver Disease (MELD) is used to allocate livers for transplantation. Patients with greater MELD scores have greater risk of death on the waitlist and are prioritized for liver transplant (LT). The MELD is capped at 40, however, and patients with calculated MELD scores >40 are not prioritized despite increased mortality. METHODS: Using United Network for Organ Sharing data, we identified patients listed for LT from February 2002 through December 2012...
May 5, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28480236/serial-procalcitonin-as-a-predictor-of-bacteremia-and-need-for-intensive-care-unit-care-in-adults-with-pneumonia-including-those-with-highest-severity-a-prospective-cohort-study
#14
Suzanne M McCluskey, Philipp Schuetz, Michael S Abers, Benjamin Bearnot, Maria E Morales, Debora Hoffman, Shreya Patel, Lauren Rosario, Victor Chiappa, Blair A Parry, Ryan T Callahan, Sheila A Bond, Kent Lewandrowski, William Binder, Michael R Filbin, Jatin M Vyas, Michael K Mansour
BACKGROUND: Procalcitonin (PCT) is a prohormone that rises in bacterial pneumonia and has promise in reducing antibiotic use. Despite these attributes, there are inconclusive data on its use for clinical prognostication. We hypothesize that serial PCT measurements can predict mortality, intensive care unit (ICU) admission, and bacteremia. METHODS: A prospective cohort study of inpatients diagnosed with pneumonia was performed at a large tertiary care center in Boston, Massachusetts...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28477055/link-between-community-acquired-pneumonia-and-vitamin%C3%A2-d-levels-in-older-patients
#15
Dongxi Lu, Jiandong Zhang, Chunming Ma, Yuanyuan Yue, Zhehua Zou, Changying Yu, Fuzai Yin
PURPOSE: To investigate the correlation between the level of 25-hydroxyvitamin D [25-(OH)D] and community-acquired pneumonia (CAP) in elderly patients. METHODS: A total of 163 older patients were chosen from those hospitalized between October 2011 and October 2012. Patients were divided into pneumonia and non-pneumonia groups, and the concentrations of 25-(OH)D (nmol/L) in serum were measured. Clinical data were then compared between the two groups and pneumonia-related risk factors were analyzed using logistic regression...
May 5, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28476529/is-suspicious-upstaging-on-multiparametric-magnetic-resonance-imaging-useful-in-improving-the-reliability-of-prostate-cancer-research-international-active-surveillance-prias-criteria-use-of-the-k-cap-registry
#16
Sagnjun Yoo, Jun Hyuk Hong, Seok-Soo Byun, Ji Youl Lee, Byung Ha Chung, Choung-Soo Kim
BACKGROUND AND OBJECTIVE: To evaluate the clinical effects of suspicious upstaging on multiparametric magnetic resonance imaging (mpMRI) for improving the quality of Prostate Cancer Research International Active Surveillance (PRIAS) criteria. MATERIAL AND METHODS: A total of 363 patients with low-risk prostate cancer (PCa) were selected from the K-CaP registry (the multicenter Korean PCa Database). Patients were divided into 2 groups according to the results of mpMRI (with or without suspicious upstaging)...
May 2, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28476005/toxicological-implications-of-selenium-nanoparticles-with-different-coatings-along-with-se-4-on-lemna-minor
#17
Roshanak Tarrahi, Alireza Khataee, Ali Movafeghi, Farkhondeh Rezanejad, Gholamreza Gohari
Nanoparticles have potential high risks for living organisms in the environment due to their specific qualities and their easy access. In the present study, selenium nanoparticles (Se NPs) with two different coatings (l-cysteine and tannic acid) were synthesized. The characteristics of particles were analyzed using XRD, FT-IR and SEM. The impact of the nanoparticles besides Se(4+), on the aquatic higher plant Lemna minor was evaluated and compared. Entrance of l-cysteine and tannic acid capped Se NPs in the roots of Lemna minor was proved by TEM and fluorescence microscopy...
April 28, 2017: Chemosphere
https://www.readbyqxmd.com/read/28474099/a-three-step-diagnosis-of-pediatric-pneumonia-at-the-emergency-department-using-clinical-predictors-c-reactive-protein-and-pneumococcal-pcr
#18
Gabriel Alcoba, Kristina Keitel, Veronica Maspoli, Laurence Lacroix, Sergio Manzano, Mario Gehri, René Tabin, Alain Gervaix, Annick Galetto-Lacour
Recommendations for the management of community-acquired pneumonia (CAP) advocate that, in the absence of the clinical and laboratory findings typical of bacterial CAP, antibiotics are not required. However, the true value of the clinical and laboratory predictors of pediatric CAP still needs to be assessed. This prospective cohort study in three emergency departments enrolled 142 children with radiological pneumonia. Pneumonia with lung consolidation was the primary endpoint; complicated pneumonia (bacteremia, empyema, or pleural effusion) was the secondary endpoint...
May 4, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28473100/coronary-artery-calcification-from-mechanism-to-molecular-imaging
#19
REVIEW
Takehiro Nakahara, Marc R Dweck, Navneet Narula, David Pisapia, Jagat Narula, H William Strauss
Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence of calcification may change portions of the arterial conduit to a noncompliant structure. Calcifications may also seed the cap of a thin cap fibroatheroma, altering tensile forces on the cap and rendering the lesion prone to rupture. Many local and systemic factors participate in this process, including hyperlipidemia, ongoing inflammation, large necrotic cores, and diabetes. Vascular cells can undergo chondrogenic or osteogenic differentiation, causing mineralization of membranous bone and formation of endochondral bone...
May 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28462806/role-of-antibiotic-prophylaxis-in-antenatal-hydronephrosis-a-systematic-review-from-the-european-association-of-urology-european-society-for-paediatric-urology-guidelines-panel
#20
REVIEW
Mesrur Selcuk Silay, Shabnam Undre, Arjun K Nambiar, Hasan Serkan Dogan, Radim Kocvara, Rien J M Nijman, Raimund Stein, Serdar Tekgul, Christian Radmayr
BACKGROUND: The benefits and harms of continuous antibiotic prophylaxis (CAP) versus observation in patients with antenatal hydronephrosis (ANH) are controversial. OBJECTIVE: The aim was to determine the effectiveness of CAP for ANH, and if beneficial to determine the best type and regimen of antibiotic and the most harmful to provide guidance for clinical practice. METHODS: A systematic literature search was performed in databases including Medline, Embase, and Cochrane in June 2015...
March 19, 2017: Journal of Pediatric Urology
keyword
keyword
93712
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"