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https://www.readbyqxmd.com/read/29054693/project-octo-pills-a-practice-model-engaging-community-pharmacists-in-the-care-of-patients-from-a-tertiary-hospital
#1
Kheng Yong Ong, Wing Lam Chung, Kaysar Mamun, Li Li Chen
Even while pharmacy practice evolves to a more patient-centric mode of practice, local hospitals, due to high patient load as well as space and resource constraints, find it challenging to conduct thorough medication review and physical medication reconciliation for all patients. In light of this, optimizing the local current healthcare system to involve community pharmacists in the care of patients from public hospitals could potentially better cater to the healthcare needs of the older population. Due to easy accessibility, community pharmacies are often the first point of contact in the healthcare system...
October 13, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29048753/medication-errors-at-hospital-admission-and-discharge-in-type-1-and-2-diabetes
#2
C Breuker, V Macioce, T Mura, Y Audurier, C Boegner, A Jalabert, M Villiet, A Castet-Nicolas, A Avignon, A Sultan
AIMS: To assess the prevalence and characteristics of medication errors at hospital admission and discharge in people with Type 1 and Type 2 diabetes, and identify potential risk factors for these errors. METHODS: This prospective observational study included all people with Type 1 (n = 163) and Type 2 diabetes (n = 508) admitted to the Diabetology-Department of the University Hospital of Montpellier, France, between 2013 and 2015. Pharmacists conducted medication reconciliation within 24 h of admission and at hospital discharge...
October 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29046815/non-adherence-to-inhalational-medications-and-associated-factors-among-patients-with-asthma-in-a-referral-hospital-in-ethiopia-using-validated-tool-tai
#3
Asnakew Achaw Ayele, Henok Getachew Tegegn
BACKGROUND: Asthma is a chronic inflammatory condition of the airways that affects roughly 358 million people globally. It is a serious global health problem with an increasing prevalence worldwide. Most people affected are in low- and middle-income countries including Ethiopia. The association between non -adherence and poor disease control is clearly stated in different literatures. The main objective of the present study was to assess self-reported non- adherence level and to identify the potential factors associated with non-adherence...
2017: Asthma research and practice
https://www.readbyqxmd.com/read/29041950/convenience-without-disclosure-a-formative-research-study-of-a-proposed-integrated-methadone-and-antiretroviral-therapy-service-delivery-model-in-dar-es-salaam-tanzania
#4
Alexis Cooke, Haneefa Saleem, Dorothy Mushi, Jessie Mbwambo, Saria Hassan, Barrot H Lambdin
BACKGROUND: Though timely initiation of antiretroviral therapy (ART) is a vital component of effective HIV prevention, care and treatment, people who inject drugs are less likely to receive ART than their non-drug using counterparts. In an effort to increase access to ART for people who inject drugs, we examined perceived benefits, challenges, and recommendations for implementing an integrated methadone and ART service delivery model at an opioid treatment program (OTP) clinic in Dar es Salaam, Tanzania...
October 18, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29037451/-city-hospital-network-and-quality-control-of-officinal-preparations
#5
C Curti, S Gallice, E Lamy, P Rathelot, P Vanelle
OBJECTIVES: In a hospital environment, the quality control of the hospital preparations allows to release homogeneous batches in a secure way. These controls are totally integrated into the process of production and can also, in certain cases, be realized for high-alert magistral preparations. In community pharmacy, these controls were not required, but the Agence régionale de santé (ARS) recently incited compounding community pharmacies to realize this type of analyses. This decision motivated the creation of a collaboration between the pharmacy department of a French teaching hospital and a society including around thirty community pharmacies having a preparatory...
October 13, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29030869/evaluation-of-the-predictive-performance-of-bleeding-risk-scores-in-patients-with-non-valvular-atrial-fibrillation-on-oral-anticoagulants
#6
S A Beshir, Z Aziz, L B Yap, K H Chee, Y L Lo
WHAT IS KNOWN AND OBJECTIVE: Bleeding risk scores (BRSs) aid in the assessment of oral anticoagulant-related bleeding risk in patients with atrial fibrillation. Ideally, the applicability of a BRS needs to be assessed, prior to its routine use in a population other than the original derivation cohort. Therefore, we evaluated the performance of 6 established BRSs to predict major or clinically relevant bleeding (CRB) events associated with the use of oral anticoagulant (OAC) among Malaysian patients...
October 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29029637/drug-resistance-patterns-following-pharmacy-stock-shortage-in-nigerian-antiretroviral-treatment-program
#7
Seema T Meloni, Beth Chaplin, John Idoko, Oche Agbaji, Sulaimon Akanmu, Godwin Imade, Prosper Okonkwo, Robert L Murphy, Phyllis J Kanki
BACKGROUND: For patients on antiretroviral therapy (ART), treatment interruptions can impact patient outcomes and result in the accumulation of drug resistance mutations leading to virologic failure. There are minimal published data on the impact of an ART stock shortage on development of drug resistance mutations (DRMs). In this report, we evaluate data from patients enrolled in the Government of Nigeria National ART Program that were receiving treatment at the time of a national drug shortage in late 2003...
October 13, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/29028437/stimulants-do-not-increase-the-risk-of-seizure-related-hospitalizations-in-children-with-epilepsy
#8
Xinyue Liu, Paul R Carney, Regina Bussing, Richard Segal, Linda B Cottler, Almut G Winterstein
OBJECTIVE: To evaluate the safety of stimulants in children with epilepsy. METHODS: In a retrospective cohort study based on Medicaid Analytic eXtract billing records from 26 U.S. states from 1999 to 2010, we identified incident stimulant use among children with epilepsy through outpatient encounter claims and pharmacy claims. We established a control group of nonusers and used frequency matching to generate index dates. We followed both cohorts for 12 months and calculated hazard ratios [HRs] of current and former use of stimulants versus no use on the outcome of seizure-related hospitalization using multivariate Cox proportional hazard models...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29028251/monitoring-surface-contamination-by-antineoplastic-drugs-in-italian-hospitals-performance-based-hygienic-guidance-values-hgvs-project
#9
Cristina Sottani, Elena Grignani, Enrico Oddone, Beatrice Dezza, Sara Negri, Simona Villani, Danilo Cottica
Antineoplastic drugs (ADs) will continue to represent a potential risk for personnel involved in the handling of these compounds and great concerns have been raised by the presence of ADs in many surveyed workplaces. Eight hospitals were investigated by means of wipe sampling for surface residue determination. Each wipe sample was tested for five ADs considered suitable exposure markers. Cyclophosphamide (CP), gemcitabine (GEM), 5-fluorouracil (5-FU), platinum-containing drugs (Pt), and epi-doxorubicin (EPI) contamination levels were measured in 85 per cent of the studied pharmacies and 93 per cent of outpatient care units (OpCUs)...
October 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29026296/trends-in-health-care-resource-utilization-and-pharmacological-management-of-copd-in-taiwan-from-2004-to-2010
#10
Ying-Huang Tsai, Tsung-Ming Yang, Chieh-Mo Lin, Shu-Yi Huang, Yu-Wen Wen
RATIONALE: COPD has attracted widespread attention worldwide. The prevalence of COPD in Taiwan has been reported, but little is known about trends in health care resource utilization and pharmacologic management in COPD treatment. OBJECTIVE: The objective of this article was to study trends in health care resource utilization, pharmacologic management, and medical costs of COPD treatment in Taiwan. MATERIALS AND METHODS: Reimbursement claims in the Taiwan National Health Insurance System from 2004 to 2010 were collected...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29025141/how-is-it-best-to-deliver-care-in-acute-medical-units-a-systematic-review
#11
L E M Reid, A J F Crookshanks, M C Jones, Z J Morrison, N I Lone, C J Weir
The majority of medical patients presenting to hospital in the UK are cared for in acute medical units (AMUs). Such units are also increasingly present internationally. Care delivery varies across units: this review aims to examine the evidence for how best to deliver AMU care.Six electronic databases and grey literature were searched. Inclusion criteria comprised interventions applied to undifferentiated patients in AMU settings. All studies were quality assessed. A narrative approach was undertaken.Nine studies, all conducted in the UK or Ireland, evaluated 1...
August 4, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29025066/supply-and-demand-application-of-lean-six-sigma-methods-to-improve-drug-round-efficiency-and-release-nursing-time
#12
Maríosa Kieran, Mary Cleary, Aoife De Brún, Aileen Igoe
Objective: To improve efficiency, reduce interruptions and reduce the time taken to complete oral drug rounds. Design: Lean Six Sigma methods were applied to improve drug round efficiency using a pre- and post-intervention design. Setting: A 20-bed orthopaedic ward in a large teaching hospital in Ireland. Participants: Pharmacy, nursing and quality improvement staff. Intervention(s): A multifaceted intervention was designed which included changes in processes related to drug trolley organization and drug supply planning...
August 19, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29024057/increasing-candidemia-incidence-from-2004-to-2015-with-a-shift-in-epidemiology-in-patients-pre-exposed-to-antifungals
#13
Berdieke Goemaere, Pierre Becker, Eric Van Wijngaerden, Johan Maertens, Isabel Spriet, Marijke Hendrickx, Katrien Lagrou
BACKGROUND: Candidemia is an important health problem in immunocompromised patients with an epidemiology varying with region, period and patient population involved. OBJECTIVES: The occurrence of candidemia and the associated species distribution over a 12-year period at a large tertiary care centre in Belgium were analysed. The trend in incidence in the intensive care units (ICUs) and non-ICUs was investigated as well as the influence of antifungal exposure on the species distribution...
October 12, 2017: Mycoses
https://www.readbyqxmd.com/read/29021008/medication-review-and-transitions-of-care-a-case-report-of-a-decade-old-medication-error
#14
Rachel Comer, Mitsi Lizer
A 69-year-old Caucasian male with a 25-year history of paranoid schizophrenia was brought to the emergency department because of violence toward the staff in his nursing facility. He was diagnosed with a urinary tract infection and was admitted to the behavioral health unit for medication stabilization. History included a five-year state psychiatric hospital admission and nursing facility placement. Because of poor cognitive function, the patient was unable to corroborate medication history, so the pharmacy student on rotation performed an in-depth chart review...
October 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29020857/optimizing-patient-education-of-oncology-medications-a-descriptive-survey-of-pharmacist-provided-patient-education-in-canada
#15
Gillian Donald, Samantha Scott, Larry Broadfield, Claudia Harding, Andrea Meade
Background The incidence of cancer is increasing in Canada due to an aging and growing population. This frequently necessitates chemotherapy, which is a high-risk treatment, often given as a part of a complex regimen with serious side effects. A review of the evidence of pharmacy-provided patient education initiatives targeted to oncology patients revealed that minimal is known about this service. Objective The objective of this study was to determine the different models of patient education of oncology medications delivered by pharmacists to adult oncology patients in a hospital or cancer center in Canada...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29020143/anti-infective-acquisition-costs-for-a-stewardship-program-getting-to-the-bottom-line
#16
Sarah K Parker, Amanda L Hurst, Cary Thurm, Matthew Millard, Timothy C Jenkins, Jason Child, Casey Dugan
Background: Though antimicrobial stewardship programs (ASPs) are in place for patient safety, financial justification is often required. In 2016, the Infectious Diseases Society of America (IDSA) recommended that anti-infective costs be measured by patient-level administration data normalized for patient census. Few publications use this methodology. Here, we aim to compare 3 methods of drug cost analysis during 3 phases of an ASP as an example of this recommendation's implementation...
July 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29019083/microbial-stability-of-pharmaceutical-and-cosmetic-products
#17
REVIEW
Huy Dao, Prit Lakhani, Anitha Police, Venkataraman Kallakunta, Sankar Srinivas Ajjarapu, Kai-Wei Wu, Pranav Ponkshe, Michael A Repka, S Narasimha Murthy
This review gives a brief overview about microbial contamination in pharmaceutical products. We discuss the distribution and potential sources of microorganisms in different areas, ranging from manufacturing sites, pharmacy stores, hospitals, to the post-market phase. We also discuss the factors that affect microbial contamination in popular dosage forms (e.g., tablets, sterile products, cosmetics). When these products are contaminated, the microorganisms can cause changes. The effects range from mild changes (e...
October 10, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/29017595/a-series-of-n-of-1-trials-to-assess-the-therapeutic-interchangeability-of-two-enalapril-formulations-in-the-treatment-of-hypertension-in-addis-ababa-ethiopia-study-protocol-for-a-randomized-controlled-trial
#18
Chalachew Alemayehu, Geoffrey Mitchell, Abraham Aseffa, Alexandra Clavarino, James McGree, Jane Nikles
BACKGROUND: Hypertension is one of the leading causes of morbidity and mortality in Ethiopia. Treatment usually involves lifelong medication use. Enalapril is a common drug for the treatment of hypertension in Ethiopia. However, the drug is expensive and, therefore, there is limited capacity for people to afford the treatment. Locally produced Enalapril is a cost-effective solution to treat the disease. However, as local medicines regulation does not include bioequivalence tests on locally produced drugs, physicians and patients need assurance about the effectiveness and safety of local generics...
October 10, 2017: Trials
https://www.readbyqxmd.com/read/29016245/effect-of-a-high-dosage-opioid-prior-authorization-policy-on-prescription-opioid-use-misuse-and-overdose-outcomes
#19
Daniel M Hartung, Hyunjee Kim, Sharia M Ahmed, Luke Middleton, Shellie Keast, Richard A Deyo, Kun Zhang, K John McConnell
High dosage opioid use is a risk factor for opioid-related overdose commonly cited in guidelines, recommendations, and policies. In 2012, the Oregon Medicaid program developed a prior authorization policy for opioid prescriptions above 120 mg per day morphine equivalent dose (MED). This study aimed to evaluate the effects of that policy on utilization, prescribing patterns, and health outcomes. Methods: Using administrative claims data from Oregon and a control state (Colorado) between 2011 and 2013, we used difference-in-differences analyses to examine changes in utilization, measures of high risk opioid use, and overdose after introduction of the policy...
October 10, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28991760/centenary-of-the-birth-of-academician-prof-dr-isak-tadzer-founder-of-the-pathophysiology-and-nuclear-medicine-in-macedonia
#20
Borislav Karanfilski
Academician Prof. Dr. Isak Tadzer was born a hundred years ago on December 24, 1916 in Sofia. He completed the primary and secondary education at the German College in Sofia. In 1935 he began his studies at the Medical Faculty in Vienna, which he had to stop because of the annexation of Austria to Germany in 1938. He returned to Bulgaria where he continued his studies and graduated from the Medical Faculty in Sofia in 1941. During the War, 1941-1944, he was forcedly mobilized and he worked as a doctor in several villages...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
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