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https://www.readbyqxmd.com/read/28078665/computerized-pharmacy-surveillance-and-alert-system-for-drug-related-problems
#1
O Ferrández, O Urbina, S Grau, J Mateu-de-Antonio, M Marin-Casino, J Portabella, S Mojal, M Riu, E Salas
WHAT IS KNOWN AND OBJECTIVE: Because of the impact of drug-related problems (DRPs) on morbidity and mortality, there is a need for computerized strategies to increase drug safety. The detection and identification of the causes of potential DRPs can be facilitated by the incorporation of a pharmacy warning system (PWS) in the computerized prescriber order entry (CPOE) and its application in the routine validation of inpatient drug therapy. A limited number of studies have evaluated a clinical decision support system to monitor drug treatment...
January 12, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28076697/development-and-characterization-of-a-mucoadhesive-sublingual-formulation-for-pain-control-extemporaneous-oxycodone-films-in-personalized-therapy
#2
Brunella Parodi, Eleonora Russo, Sara Baldassari, Guendalina Zuccari, Sara Pastorino, Mengying Yan, Karthik Neduri, Gabriele Caviglioli
OBJECTIVE: The aim of this work was the development of mucoadhesive sublingual films, prepared using a casting method, for the administration of oxycodone. MATERIALS AND METHODS: A solvent casting method was employed to prepare the mucoadhesive films. A calibrated pipette was used to deposit single aliquots of different polymeric solutions on a polystyrene plate lid. Among the various tested polymers, hydroxypropylcellulose at low and medium molecular weight (HPC) and pectin at two different degrees of esterification (PC) were chosen for preparing solutions with good casting properties, capable of producing films suitable for mucosal application...
January 11, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28070147/liposomal-bupivacaine-in-total-hip-arthroplasty-do-the-results-justify-the-cost
#3
Jason A Beachler, Daniel M Kopolovich, Creighton C Tubb, Siraj A Sayeed
INTRODUCTION: Liposomal bupivacaine has a paucity of data regarding narcotic requirements and hospital length of stay in comparison to other peri-articular injections, specifically in the total hip arthroplasty (THA) population. METHODS: 69 patients who underwent THA by a single surgeon were divided into two cohorts over a 3 year period in this retrospective study comparing narcotic requirements, hospital length of stay and cost. The study group (n = 29) received liposomal bupivacaine whereas a matched control group (n = 40) received a pharmacy-mixed cocktail in peri-articular structures...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28069680/medication-errors-associated-with-transition-from-insulin-pens-to-insulin-vials
#4
Adam N Trimble, Bryan Bishop, Nancy Rampe
PURPOSE: Three insulin administration errors that occurred after a hospital's transition from insulin pens to vials are described, and process improvement initiatives implemented to prevent future errors are reviewed. SUMMARY: In response to numerous reports and warnings related to the risk of insulin pen sharing, a 450-bed community hospital made a transition from insulin pens to insulin vials. Shortly after this transition, three major medication errors involving insulin occurred...
January 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28064169/potentially-inappropriate-medication-prescribing-is-associated-with-socioeconomic-factors-a-spatial-analysis-in-the-french-nord-pas-de-calais-region
#5
Jean-Baptiste Beuscart, Michael Genin, Corrine Dupont, David Verloop, Alain Duhamel, Marguerite-Marie Defebvre, François Puisieux
BACKGROUND: potentially inappropriate medication (PIM) prescribing is common in older people and leads to adverse events and hospital admissions. OBJECTIVE: to determine whether prevalence of PIM prescribing varies according to healthcare supply and socioeconomic status. METHODS: all prescriptions dispensed at community pharmacies for patients aged 75 and older between 1 January  and 31 March 2012 were retrieved from French Health Insurance Information System of the Nord-Pas-de-Calais Region for patients affiliated to the Social Security scheme...
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28060051/e-prescribing-and-adverse-drug-events-an-observational-study-of-the-medicare-part-d-population-with-diabetes
#6
Meghan Hufstader Gabriel, Christopher Powers, William Encinosa, Julie P W Bynum
BACKGROUND: Although the adoption of e-prescriptions among physicians has increased substantially under the Medicare Improvements for Patients and Providers Act and Meaningful Use programs, little is known of its impact on patient outcomes. OBJECTIVE: To examine the impact of e-prescribing on emergency visits or hospitalizations for diabetes-related adverse drug events (ADEs) including hypoglycemia. DESIGN: This is a prospective, observational cohort study with patient fixed effects...
January 3, 2017: Medical Care
https://www.readbyqxmd.com/read/28059697/digital-literacy-knowledge-and-needs-of-pharmacy-staff-a-systematic-review
#7
Katie MacLure, Derek Stewart
OBJECTIVE: To explore the digital literacy knowledge and needs of pharmacy staff including pharmacists, graduate (pre-registration) pharmacists, pharmacy technicians, dispensing assistants and medicine counter assistants. METHODS: A systematic review was conducted following a pre-published protocol. Two reviewers systematically performed the reproducible search, followed by independent screening of titles/abstracts then full papers, before critical appraisal and data extraction...
October 7, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28058977/the-shrinking-of-formalized-nutrition-education-in-health-professions-curricula-and-postgraduate-training
#8
Gordon S Sacks
The quantity of formalized nutrition education is shrinking in curricula of health professions, such as physicians, nurses, dietitians, and pharmacists. The current nutrition education being taught in U.S. schools of healthcare professionals does not appropriately prepare students for identification of patients at nutrition risk or management of undernourished hospitalized patients with specialized nutrition therapies. In U.S. schools of pharmacy, parenteral nutrition is considered a highly specialized and advanced practice so little time is devoted to this area and more attention is focused on chronic disease state management (ie, hypertension, diabetes mellitus, and congestive heart failure)...
January 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28057958/reviewer-acknowledgments
#9
(no author information available yet)
We thank all the peer reviewers who completed manuscript reviews for Hospital Pharmacy in 2016. These professionals contributed their time and expertise to ensure that the articles published were clinically relevant and of high scientific quality and adhered to ethical standards. We honor their contributions to the field through this important, and often unrecognized, activity.
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28057953/daclizumab
#10
Anne P Kim, Danial E Baker
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are are available online to subscribers...
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28057948/impact-on-cdc-guideline-compliance-after-incorporating-pharmacy-in-a-pneumococcal-vaccination-screening-process
#11
Elizabeth Pickren, Brad Crane
Background: Centers for Disease Control and Prevention (CDC) guidelines for pneumococcal vaccinations were updated in 2014. Given the complexity of the guidelines and the fact that hospitals are no longer required to keep records for pneumococcal vaccinations, many hospitals are determining whether to continue this service. Objective: The primary objective of this study was to determine the impact on compliance with the revised pneumococcal vaccination guidelines from the CDC after involving pharmacy in the screening and selection processes...
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28057947/pentostatin-cyclophosphamide-and-rituximab-pcr-regimen
#12
Dominic A Solimando, J Aubrey Waddell
The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases. Questions or suggestions for topics should be addressed to Dominic A. Solimando, Jr., President, Oncology Pharmacy Services, Inc., 4201 Wilson Blvd #110-545, Arlington, VA 22203, email: OncRxSvc@comcast...
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28056998/factors-associated-with-occupancy-of-pharmacist-positions-in-public-sector-hospitals-in-uganda-a-cross-sectional-study
#13
Thomas Ocwa Obua, Richard Odoi Adome, Paul Kutyabami, Freddy Eric Kitutu, Pakoyo Fadhiru Kamba
BACKGROUND: Pharmacists are invaluable resources in health care. Their expertise in pharmacotherapy and medicine management both ensures that medicines of appropriate quality are available in health facilities at the right cost and are used appropriately. Unfortunately, some countries like Uganda have shortage of pharmacists in public health facilities, the dominant providers of care. This study investigated the factors that affect the occupancy of pharmacist positions in Uganda's public hospitals, including hiring patterns and job attraction and retention...
January 5, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28054236/antibiotic-resistance-patterns-of-escherichia-coli-urinary-isolates-and-comparison-with-antibiotic-consumption-data-over-10%C3%A2-years-2005-2014
#14
P J Stapleton, D J Lundon, R McWade, N Scanlon, M M Hannan, F O'Kelly, M Lynch
INTRODUCTION: Escherichia coli is a common cause of urinary tract infections (UTI). Reviews of antibiotic resistance of this organism can inform choice of empiric treatment of UTI and other infections and strategies for combating antimicrobial resistance. We reviewed laboratory and hospital pharmacy records to assess trends in non-susceptibility rates and the effect of antimicrobial stewardship interventions. METHODS: A retrospective observational study of isolates of E...
January 4, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28049901/improvement-of-clinical-skills-through-pharmaceutical-education-and-clinical-research
#15
Junko Ishizaki
 Professors and teaching staff in the field of pharmaceutical sciences should devote themselves to staying abreast of relevant education and research. Similarly those in clinical pharmacies should contribute to the advancement of pharmaceutical research and the development of next generation pharmacists and pharmaceuticals. It is thought that those who work in clinical pharmacies should improve their own skills and expertise in problem-finding and -solving, i.e., "clinical skills". They should be keen to learn new standard treatments based on the latest drug information, and should try to be in a position where collecting clinical information is readily possible...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28049892/maintenance-of-clinical-expertise-and-clinical-research-by-the-clinical-professors-at-gifu-pharmaceutical-university
#16
Tomoya Tachi, Yoshihiro Noguchi, Hitomi Teramachi
 The clinical professors at Gifu Pharmaceutical University (GPU) provide pharmaceutical services at GPU Pharmacy, Gifu University Hospital, and Gifu Municipal Hospital to keep their clinical skills up-to-date; they also perform clinical research in collaboration with many clinical institutes. The Laboratory of Clinical Pharmacy is part of the Department of Pharmacy Practice and Science, to which the clinical professors belong, and is composed of three clinical professors (a professor, an associate professor, and an assistant professor)...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28049889/importance-of-pharmaceutical-training-and-clinical-research-at-medical-facilities
#17
Michiaki Myotoku
 To respond to advancements in medical techniques, and to address the separation of medical and dispensary practices, clinical professors are required to educate human resource staff to become highly-skilled pharmacists. For this purpose, it is extremely important for these professors to learn about cutting-edge practical skills and knowledge, as well as to advance their expertise. In addition, they need to conduct clinical research in cooperation with relevant facilities. As our university does not have its own hospital or pharmacy, it is important to provide training for clinical professors in clinical facilities...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28045653/intelligent-monitoring-system-for-antiviral-pharmacotherapy-in-patients-with-chronic-hepatitis-c-simon-vc
#18
Luis Margusino-Framiñán, Purificación Cid-Silva, Álvaro Mena-de-Cea, Ana Isabel Sanclaudio-Luhía, José Antonio Castro-Castro, Guillermo Vázquez-González, Isabel Martín-Herranz
Two out of six strategic axes of pharmaceutical care in our hospital are quality and safety of care, and the incorporation of information technologies. Based on this, an information system was developed in the outpatient setting for pharmaceutical care of patients with chronic hepatitis C, SiMON-VC, which would improve the quality and safety of their pharmacotherapy. The objective of this paper is to describe requirements, structure and features of Si- MON-VC. Requirements demanded were that the information system would enter automatically all critical data from electronic clinical records at each of the visits to the Outpatient Pharmacy Unit, allowing the generation of events and alerts, documenting the pharmaceutical care provided, and allowing the use of data for research purposes...
January 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28045651/pharmacotherapy-follow-up-of-patients-under-treatment-with-biologic-agents-for-chronic-inflammatory-systemic-conditions-an-agreement-among-hospital-pharmacists-for-the-standardized-collection-of-a-minimum-set-of-data
#19
Miguel Ángel Calleja Hernández, Alicia Herrero Ambrosio, María Jesús Lamas Díaz, Julio Martínez Cutillas, Jose Luis Poveda Andrés, Belén Aragón
BACKGROUND AND OBJECTIVE: The objective of this study was to reach a consensus on the minimum set of data that would allow to optimize the pharmacotherapy follow-up of patients on biologic agents for chronic systemic inflammatory conditions, through structured and standardized collection with an electronic tool in the hospital pharmacy. MATERIALS AND METHOD: A scientific committee was formed (n = 5 hospital pharmacists). The Delphi Technique was used, 2 rounds of consultation by e-mail for hospital pharmacists...
January 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28044455/health-care-resource-utilization-and-costs-of-california-medicaid-patients-with-schizophrenia-treated-with-paliperidone-palmitate-once-monthly-or-atypical-oral-antipsychotic-treatment
#20
Jacqueline A Pesa, Dilesh Doshi, Li Wang, Huseyin Yuce, Onur Baser
OBJECTIVE: To compare all-cause health care utilization and costs between patients with schizophrenia treated with once-monthly paliperidone palmitate (PP1M; Invega® Sustenna(®)) and atypical oral antipsychotic therapy (OAT). METHODS: This was a retrospective claims-based analysis among adult California Medicaid (Medi-Cal) patients with schizophrenia having ≥2 claims for PP1M or OAT from 01JUL2009-31DEC2013 and continuous health plan enrollment for ≥1 year pre- and post-index date (PP1M or OAT initiation date)...
January 3, 2017: Current Medical Research and Opinion
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