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https://www.readbyqxmd.com/read/28637136/virtual-environment-navigation-with-look-around-mode-to-explore-new-real-spaces-by-people-who-are-blind
#1
Orly Lahav, Hadas Gedalevitz, Steven Battersby, David Brown, Lindsay Evett, Patrick Merritt
BACKGROUND: This paper examines the ability of people who are blind to construct a mental map and perform orientation tasks in real space by using Nintendo Wii technologies to explore virtual environments. The participant explores new spaces through haptic and auditory feedback triggered by pointing or walking in the virtual environments and later constructs a mental map, which can be used to navigate in real space. METHODS: The study included 10 participants who were congenitally or adventitiously blind, divided into experimental and control groups...
February 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28637069/-preference-changes-regarding-future-work-area-and-intended-position-among-german-residents-after-four-years-of-residency
#2
Stine Ziegler, Hendrik van den Bussche, Farina Römer, Lea Krause-Solberg, Martin Scherer
Introduction We investigated the preferences of medical residents in Germany with regard to future working place (hospital or private practice) and position (employment/self-employment in private practice; resp. specialist/senior or chief physician in the hospital). This is analysed in a gender comparative perspective, including the influence of parenthood. Methods Annual postal surveys among graduates of seven medical faculties in Germany from their last year ("Practical Year") until after four years of postgraduate training...
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28636482/impact-of-freeway-weaving-segment-design-on-light-duty-vehicle-exhaust-emissions
#3
Qing Li, Fengxiang Qiao, Lei Yu, Shuyan Chen, Tiezhu Li
In United States, 26% of greenhouse gas emissions is emitted from the transportation sector, which meanwhile accompanies with enormous toxic emissions to humans, such as CO, NOx, and HC, approximately 2.5% and 2.44% of a total exhaust emission for a petrol and diesel engine, respectively. These exhaust emissions are typically subject to vehicles' intermittent operations, such as hard acceleration and hard braking. In practice, drivers are inclined to operate intermittently while driving through a weaving segment, due to complex vehicle maneuvering for weaving...
June 21, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28635403/psychomotor-skills-assessment-by-motion-analysis-in-minimally-invasive-surgery-on-an-animal-organ
#4
Erlend Fagertun Hofstad, Cecilie Våpenstad, Lars Eirik Bø, Thomas Langø, Esther Kuhry, Ronald Mårvik
BACKGROUND: A high level of psychomotor skills is required to perform minimally invasive surgery (MIS) safely. To be able to measure these skills is important in the assessment of surgeons, as it enables constructive feedback during training. The aim of this study was to test the validity of an objective and automatic assessment method using motion analysis during a laparoscopic procedure on an animal organ. MATERIAL AND METHODS: Experienced surgeons in laparoscopy (experts) and medical students (novices) performed a cholecystectomy on a porcine liver box model...
February 8, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28634632/can-a-virtual-reality-surgical-simulation-training-provide-a-self-driven-and-mentor-free-skills-learning-investigation-of-the-practical-influence-of-the-performance-metrics-from-the-virtual-reality-robotic-surgery-simulator-on-the-skill-learning-and-associated
#5
Gyusung I Lee, Mija R Lee
BACKGROUND: While it is often claimed that virtual reality (VR) training system can offer self-directed and mentor-free skill learning using the system's performance metrics (PM), no studies have yet provided evidence-based confirmation. This experimental study investigated what extent to which trainees achieved their self-learning with a current VR simulator and whether additional mentoring improved skill learning, skill transfer and cognitive workloads in robotic surgery simulation training...
June 20, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28631283/assessing-causal-effects-of-early-life-course-factors-on-early-childhood-caries-in-5-year-old-ugandan-children-using-directed-acyclic-graphs-dags-a-prospective-cohort-study
#6
Nancy Birungi, Lars T Fadnes, Arabat Kasangaki, Victoria Nankabirwa, Isaac Okullo, Stein A Lie, James K Tumwine, Anne N Åstrøm
OBJECTIVE: To estimate the effect of distal and proximal early life-course factors on early childhood caries (ECC) in 5-year-old Ugandan children, particularly focusing on the causal effect of exclusive breast feeding (EBF) on ECC using directed acyclic graphs (DAGs) for confounder selection. METHODS: This study had a nested prospective cohort design, focusing on 5 years of follow-ups of caregiver-children pairs from the PROMISE-EBF trial (ClinicalTrials.gov no: NCT00397150) conducted in 2011 in Eastern Uganda...
June 20, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28630744/maternal-predictors-of-neonatal-outcomes-after-emergency-cesarean-section-a-retrospective-study-in-three-rural-district-hospitals-in-rwanda
#7
Naome Nyirahabimana, Christine Minani Ufashingabire, Yihan Lin, Bethany Hedt-Gauthier, Robert Riviello, Jackline Odhiambo, Joel Mubiligi, Martin Macharia, Stephen Rulisa, Illuminee Uwicyeza, Patient Ngamije, Fulgence Nkikabahizi, Theoneste Nkurunziza
BACKGROUND: In sub-Saharan Africa, neonatal mortality post-cesarean delivery is higher than the global average. In this region, most emergency cesarean sections are performed at district hospitals. This study assesses maternal predictors for poor neonatal outcomes post-emergency cesarean delivery in three rural district hospitals in Rwanda. METHODS: This retrospective study includes a random sample of 441 neonates from Butaro, Kirehe and Rwinkwavu District Hospitals, born between 01 January and 31 December 2015...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28629879/prediction-of-cognition-in-parkinson-s-disease-with-a-clinical-genetic-score-a-longitudinal-analysis-of-nine-cohorts
#8
Ganqiang Liu, Joseph J Locascio, Jean-Christophe Corvol, Brendon Boot, Zhixiang Liao, Kara Page, Daly Franco, Kyle Burke, Iris E Jansen, Ana Trisini-Lipsanopoulos, Sophie Winder-Rhodes, Caroline M Tanner, Anthony E Lang, Shirley Eberly, Alexis Elbaz, Alexis Brice, Graziella Mangone, Bernard Ravina, Ira Shoulson, Florence Cormier-Dequaire, Peter Heutink, Jacobus J van Hilten, Roger A Barker, Caroline H Williams-Gray, Johan Marinus, Clemens R Scherzer
BACKGROUND: Cognitive decline is a debilitating manifestation of disease progression in Parkinson's disease. We aimed to develop a clinical-genetic score to predict global cognitive impairment in patients with the disease. METHODS: In this longitudinal analysis, we built a prediction algorithm for global cognitive impairment (defined as Mini Mental State Examination [MMSE] ≤25) using data from nine cohorts of patients with Parkinson's disease from North America and Europe assessed between 1986 and 2016...
June 16, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28629684/united-states-medical-licensing-examination-and-american-board-of-pediatrics-certification-examination-results-does-the-residency-program-contribute-to-trainee-achievement
#9
Thomas R Welch, Brad G Olson, Elizabeth Nelsen, Gary L Beck Dallaghan, Gloria A Kennedy, Ann Botash
OBJECTIVE: To determine whether training site or prior examinee performance on the US Medical Licensing Examination (USMLE) step 1 and step 2 might predict pass rates on the American Board of Pediatrics (ABP) certifying examination. STUDY DESIGN: Data from graduates of pediatric residency programs completing the ABP certifying examination between 2009 and 2013 were obtained. For each, results of the initial ABP certifying examination were obtained, as well as results on National Board of Medical Examiners (NBME) step 1 and step 2 examinations...
June 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28629488/supporting-in-an-existential-crisis-a-mixed-methods-evaluation-of-a-training-model-in-palliative-care
#10
Lisa Sand, Mariann Olsson, Peter Strang
BACKGROUND: Palliative care staff often report that they lack the skills and confidence to provide support during an existential crisis. Consequently, there is a definite need for a training program in this area. OBJECTIVE: Our aim was to investigate whether a training model could give palliative care staff increased knowledge, awareness, and preparedness-all useful tools for providing support. METHODS: A mixed-methods research design was used...
June 20, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28629165/a-cost-effective-vehicle-localization-solution-using-an-interacting-multiple-model-unscented-kalman-filters-imm-ukf-algorithm-and-grey-neural-network
#11
Qimin Xu, Xu Li, Ching-Yao Chan
In this paper, we propose a cost-effective localization solution for land vehicles, which can simultaneously adapt to the uncertain noise of inertial sensors and bridge Global Positioning System (GPS) outages. First, three Unscented Kalman filters (UKFs) with different noise covariances are introduced into the framework of Interacting Multiple Model (IMM) algorithm to form the proposed IMM-based UKF, termed as IMM-UKF. The IMM algorithm can provide a soft switching among the three UKFs and therefore adapt to different noise characteristics...
June 18, 2017: Sensors
https://www.readbyqxmd.com/read/28628601/the-damage-control-surgery-in-austere-environments-research-group-dcsaerg-a-dynamic-program-to-facilitate-real-time-telementoring-telediagnosis-to-address-exsanguination-in-extreme-and-austere-environments
#12
Andrew W Kirkpatrick, Jessica L McKee, Paul B McBeth, Chad G Ball, Anthony LaPorta, Timothy Broderick, Tim Leslie, David King, Heather E Wright Beatty, Jocelyn Keillor, Homer Tien
Hemorrhage is the most preventable cause of posttraumatic death. Many cases are potentially anatomically salvageable, yet remain lethal without logistics or trained personnel to deliver diagnosis or resuscitative surgery in austere environments. Revolutions in technology for remote mentoring of ultrasound and surgery may enhance capabilities to utilize the skill sets of non-physicians. Thus, our research collaborative explored remote mentoring to empower non-physicians to address junctional and torso hemorrhage control in austere environments...
July 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28628163/-quantitative-structure-activity-relationship-model-for-prediction-of-cardiotoxicity-of-chemical-components-in-traditional-chinese-medicines
#13
(no author information available yet)
OBJECTIVE: Some quantitative structure-activity relationship (QSAR) models have been developed to predict cardiac toxicity of drugs, which have limited predictive power due to based on hERG channel inhibition. The objective of this study was try to develop a QSAR model based on all kinds of cardiac adverse effects, and to predict the potential cardiotoxicity of chemical components in traditional Chinese medicines (TCM). METHODS: In this study, the compounds data of all kinds of cardiac adverse reactions were selected as the training set...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28627811/energy-based-neural-networks-as-a-tool-for-harmony-based-virtual-screening
#14
Nelly I Zhokhova, Igor I Baskin
In Energy-Based Neural Networks (EBNNs), relationships between variables are captured by means of a scalar function conventionally called "energy". In this article, we introduce a procedure of "harmony search", which looks for compounds providing the lowest energies for the EBNNs trained on active compounds. It can be considered as a special kind of similarity search that takes into account regularities in the structures of active compounds. In this paper, we show that harmony search can be used for performing virtual screening...
June 19, 2017: Molecular Informatics
https://www.readbyqxmd.com/read/28627505/monitoring-alert-and-drowsy-states-by-modeling-eeg-source-nonstationarity
#15
Sheng-Hsiou Hsu, Tzyy-Ping Jung
As a human brain performs various cognitive functions within ever-changing environments, states of the brain characterized by recorded brain activities such as electroencephalogram (EEG) are inevitably nonstationary. The challenges of analyzing the nonstationary EEG signals include finding neurocognitive sources that underlie different brain states and using EEG data to quantitatively assess the state changes. Approach. This study hypothesizes that brain activities under different states, e.g. levels of alertness, can be modeled as distinct compositions of statistically independent sources using independent component analysis (ICA)...
June 19, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28627411/impact-of-procedural-training-on-pregnancy-outcomes-and-career-satisfaction-in-female-post-graduate-medical-trainees-in-the-united-states
#16
Jennifer S Davids, Rebecca E Scully, Nelya Melnitchouk
BACKGROUND: Compared to non-procedural fields, procedural specialization requires longer training, less flexible schedules, and greater physical demands. The impact of these factors on pregnancy, maternity outcomes, and career satisfaction has not been well described. STUDY DESIGN: Data were gathered from 738 United States postgraduate medical trainee mothers via an anonymous, IRB-approved online survey. Univariate analysis was performed using Chi-squared tests...
June 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28626972/nirca-an-artificial-neural-network-based-insulin-resistance-calculator
#17
Konrad Stawiski, Iwona Pietrzak, Wojciech Młynarski, Wojciech Fendler, Agnieszka Szadkowska
BACKGROUND: Direct measurement of insulin sensitivity in children with type 1 diabetes is cumbersome and time consuming. OBJECTIVE: The aim of our study was to develop novel, accurate machine learning-based methods of insulin resistance estimation in children with type 1 diabetes. METHODS: A hyperinsulinemic hyperglycemic clamp study was performed to evaluate the glucose disposal rate (GDR) in a study group consisting of 315 patients aged 7...
June 19, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28625502/a-computable-phenotype-improves-cohort-ascertainment-in-a-pediatric-pulmonary-hypertension-registry
#18
Alon Geva, Jessica L Gronsbell, Tianxi Cai, Tianrun Cai, Shawn N Murphy, Jessica C Lyons, Michelle M Heinz, Marc D Natter, Nandan Patibandla, Jonathan Bickel, Mary P Mullen, Kenneth D Mandl
OBJECTIVES: To compare registry and electronic health record (EHR) data mining approaches for cohort ascertainment in patients with pediatric pulmonary hypertension (PH) in an effort to overcome some of the limitations of registry enrollment alone in identifying patients with particular disease phenotypes. STUDY DESIGN: This study was a single-center retrospective analysis of EHR and registry data at Boston Children's Hospital. The local Informatics for Integrating Biology and the Bedside (i2b2) data warehouse was queried for billing codes, prescriptions, and narrative data related to pediatric PH...
June 15, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28624156/a-noninvasive-blood-based-combinatorial-proteomic-biomarker-assay-to-detect-breast-cancer-in-women-under-the-age-of-50-years
#19
Ana P Lourenco, Kasey L Benson, Meredith C Henderson, Michael Silver, Elias Letsios, Quynh Tran, Kelly J Gordon, Sherri Borman, Christa Corn, Rao Mulpuri, Wendy Smith, Josie Alpers, Carrie Costantini, Nitin Rohatgi, Rebecca Yang, Ali Haythem, Shah Biren, Michael Morris, Fred Kass, David E Reese
BACKGROUND: Despite significant advances in breast imaging, the ability to detect breast cancer (BC) remains a challenge. To address the unmet needs of the current BC detection paradigm, 2 prospective clinical trials were conducted to develop a blood-based combinatorial proteomic biomarker assay (Videssa Breast) to accurately detect BC and reduce false positives (FPs) from suspicious imaging findings. PATIENTS AND METHODS: Provista-001 and Provista-002 (cohort one) enrolled Breast Imaging Reporting and Data System 3 or 4 women aged under 50 years...
May 23, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28623363/machine-learning-workflow-to-enhance-predictions-of-adverse-drug-reactions-adrs-through-drug-gene-interactions-application-to-drugs-for-cutaneous-diseases
#20
Kalpana Raja, Matthew Patrick, James T Elder, Lam C Tsoi
Adverse drug reactions (ADRs) pose critical public health issues, affecting over 6% of hospitalized patients. While knowledge of potential drug-drug interactions (DDI) is necessary to prevent ADR, the rapid pace of drug discovery makes it challenging to maintain a strong insight into DDIs. In this study, we present a novel literature-mining framework for enhancing the predictions of DDIs and ADR types by integrating drug-gene interactions (DGIs). The ADR types were adapted from a DDI corpus, including i) adverse effect; ii) effect at molecular level; iii) effect related to pharmacokinetics; and iv) DDIs without known ADRs...
June 16, 2017: Scientific Reports
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