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Training performance modeling

Cecilia Nilsson, Jette Led Sorensen, Lars Konge, Mikkel Westen, Morten Stadeager, Bent Ottesen, Flemming Bjerrum
BACKGROUND: Inexperienced operating assistants are often tasked with the important role of handling camera navigation during laparoscopic surgery. Incorrect handling can lead to poor visualization, increased operating time, and frustration for the operating surgeon-all of which can compromise patient safety. The objectives of this trial were to examine how to train laparoscopic camera navigation and to explore the transfer of skills to the operating room. MATERIALS AND METHODS: A randomized, single-center superiority trial with three groups: The first group practiced simulation-based camera navigation tasks (camera group), the second group practiced performing a simulation-based cholecystectomy (procedure group), and the third group received no training (control group)...
October 21, 2016: Surgical Endoscopy
Ruifeng Liu, Xueping Yu, Anders Wallqvist
Chemical toxicity is conventionally evaluated in animal models. However, animal models are resource intensive; moreover, they face ethical and scientific challenges because the outcomes obtained by animal testing may not correlate with human responses. To develop an alternative method for assessing chemical toxicity, we investigated the feasibility of using chemical-induced genome-wide expression changes in cultured human cells to predict the potential of a chemical to cause specific organ injuries in humans...
October 21, 2016: Chemical Research in Toxicology
Brun Jean-Frédéric, Varlet-Marie Emmanuelle, Fédou Christine, Raynaud de Mauverger Eric
We investigated to what extent a prediction of the 'ideal' hematocrit based on individual hemorheological profile with an equation of viscosity is relevant in trained athletes, and how the agreement between theoretical and actual values is modified by changes in training volume and performance. Elite soccer players (national level: 18-32 yr, weight 61-83 kg, body mass index 20.9-25.8 kg/m2) were seen twice at one year interval. Hemorheologic parameters were measured with the MT90 viscometer and the Myrenne aggregometer the theoretical bell-shaped curve of hematocrit/viscosity ratio as a function of hematocrit was reconstructed with Quemada's equation using actual plasma viscosity and red cell rigidity to predict hematocrit/viscosity at various hematocrit levels...
October 15, 2016: Clinical Hemorheology and Microcirculation
Brun Jean-Frédéric, Varlet-Marie Emmanuelle, Raynaud de Mauverger Eric
The hemorheological theory of optimal hematocrit suggests that the best value of hematocrit (hct) should be that which results in the highest value of the hematocrit/viscosity (h/η) ratio. Trained athletes compared to sedentary subjects have a lower hct, but a higher h/η, and endurance training reduces the discrepancy between the actual hct and the ⪡ideal⪢ hct that can be predicted with a theoretical curve of h/ηvs hct constructed with Quemada's model. In this study we investigated what becomes this homeostasis of h/η and hct during acute exercise in 19 athletes performing a 25 min exercise test...
October 17, 2016: Clinical Hemorheology and Microcirculation
Noortje H Rijken, Remko Soer, Ewold de Maar, Hilco Prins, Wouter B Teeuw, Jan Peuscher, Frits G J Oosterveld
The aim of this pilot study was to investigate the effects of an intervention consisting of mental coaching combined with either electro encephalogram (EEG) alpha power feedback or heart rate variability (HRV) feedback on HRV, EEG outcomes and self-reported factors related to stress, performance, recovery and sleep quality in elite athletes. A prospective pilot study was performed with two distinct cohorts. Soccer players were provided with four sessions of mental coaching combined with daily HRV biofeedback (Group A); track and field athletes were provided with four sessions of mental coaching in combination with daily neurofeedback (Group B)...
October 19, 2016: Applied Psychophysiology and Biofeedback
Michel van Schaardenburgh, Martin Wohlwend, Øivind Rognmo, Erney J R Mattsson
PURPOSE: Mitochondria are essential for energy production in the muscle cell and for this they are dependent upon a sufficient supply of oxygen by the circulation. Exercise training has shown to be a potent stimulus for physiological adaptations and mitochondria play a central role. Whether changes in mitochondrial respiration are seen after exercise in patients with a reduced circulation is unknown. The aim of the study was to evaluate the time course and whether one session of calf raise exercise stimulates mitochondrial respiration in the calf muscle of patients with peripheral vascular disease...
2016: PloS One
Frederico Rosário, Marcin Wojnar, Cristina Ribeiro
BACKGROUND: The effectiveness of interventions to increase general practitioners' management of alcohol problems is affected by their attitudes toward at-risk drinkers. Tailoring training programs to general practitioners' attitudes may be useful in increasing alcohol screening and brief advice. OBJECTIVES: to determine whether general practitioners could be divided into distinct groups based on their attitudes toward at-risk drinkers. Another aim of this study was to develop and validate a model for classifying general practitioners into distinct groups...
October 19, 2016: Substance Use & Misuse
Tomaž Nerat, Igor Locatelli, Mitja Kos
INTRODUCTION: Type 2 diabetes is a major burden for the payer, however, with proper medication adherence, diet and exercise regime, complication occurrence rates, and consequently costs can be altered. AIMS: The aim of this study was to conduct a cost-effectiveness analysis on real patient data and evaluate which medication adherence or lifestyle intervention is less cost demanding for the payer. METHODS: Medline was searched systematically for published type 2 diabetes interventions regarding medication adherence and lifestyle in order to determine their efficacies, that were then used in the cost-effectiveness analysis...
2016: Patient Preference and Adherence
Attila Oláh, Dalma Kellermayer, Csaba Mátyás, Balázs Tamás Németh, Árpád Lux, Lilla Szabó, Marianna Török, Mihály Ruppert, Anna Meltzer, Alex Ali Sayour, Kálmán Benke, István Hartyánszky, Béla Merkely, Tamás Radovits
PURPOSE: Long-term exercise training is associated with characteristic cardiac adaptation, termed athlete's heart. Our research group previously characterized in vivo left ventricular (LV) function of exercise-induced cardiac hypertrophy in detail in a rat model, however the effect of detraining on LV function is still unclear. We aimed at evaluating the reversibility of functional alterations of athlete's heart after detraining. METHODS: Rats (n=16) were divided into detrained exercised (DEx) and detrained control (DCo) groups...
October 14, 2016: Medicine and Science in Sports and Exercise
Ralf Jäger, Martin Purpura, Jason D Stone, Stephanie M Turner, Anthony J Anzalone, Micah J Eimerbrink, Marco Pane, Angela Amoruso, David S Rowlands, Jonathan M Oliver
Probiotics have immunomodulatory effects. However, little is known about the potential benefit of probiotics on the inflammation subsequent to strenuous exercise. In a double-blind, randomized, placebo controlled, crossover design separated by a 21-day washout, 15 healthy resistance-trained men ingested an encapsulated probiotic Streptococcus (S.) thermophilus FP4 and Bifidobacterium (B.) breve BR03 at 5 bn live cells (AFU) concentration each, or a placebo, daily for 3 weeks prior to muscle-damaging exercise (ClinicalTrials...
October 14, 2016: Nutrients
Tao Ma, Fen Wang, Jianjun Cheng, Yang Yu, Xiaoyun Chen
The development of intrusion detection systems (IDS) that are adapted to allow routers and network defence systems to detect malicious network traffic disguised as network protocols or normal access is a critical challenge. This paper proposes a novel approach called SCDNN, which combines spectral clustering (SC) and deep neural network (DNN) algorithms. First, the dataset is divided into k subsets based on sample similarity using cluster centres, as in SC. Next, the distance between data points in a testing set and the training set is measured based on similarity features and is fed into the deep neural network algorithm for intrusion detection...
October 13, 2016: Sensors
Sridhar Ravi, Dmitry Kolomenskiy, Thomas Engels, Kai Schneider, Chun Wang, Jörn Sesterhenn, Hao Liu
The natural wind environment that volant insects encounter is unsteady and highly complex, posing significant flight-control and stability challenges. It is critical to understand the strategies insects employ to safely navigate in natural environments. We combined experiments on free flying bumblebees with high-fidelity numerical simulations and lower-order modeling to identify the mechanics that mediate insect flight in unsteady winds. We trained bumblebees to fly upwind towards an artificial flower in a wind tunnel under steady wind and in a von Kármán street formed in the wake of a cylinder...
October 18, 2016: Scientific Reports
Santiago Marfà, Josep Marti, Adalgiza Reyes, Gregori Casals, Guillermo Fernández-Varo, Silvia Carvajal, J C García-Valdecasas, Josep Fuster, Wladimiro Jiménez
Colorectal cancer (CRC) is one of the most common cancers in the developed countries, and nearly 70% of patients with CRC develop colorectal liver metastases (CRLMs). During the last decades, several scores have been proposed to predict recurrence after CRLM resection. However, these risk scoring systems do not accurately reflect the prognosis of these patients. Therefore, this investigation was designed to identify a proteomic profile in human hepatic tumor samples to classify patients with CRLM as "mild" or "severe" based on the 5-year survival...
October 2016: Translational Oncology
Loïc Peter, Diana Mateus, Pierre Chatelain, Denis Declara, Noemi Schworm, Stefan Stangl, Gabriele Multhoff, Nassir Navab
The examination of biopsy samples plays a central role in the diagnosis and staging of numerous diseases, including most cancer types. However, because of the large size of the acquired images, the localization and quantification of diseased portions of a tissue is usually time-consuming, as pathologists must scroll through the whole slide to look for objects of interest which are often only scarcely distributed. In this work, we introduce an approach to facilitate the visual inspection of large digital histopathological slides...
October 5, 2016: Medical Image Analysis
Leanne M Boehm, Eduard E Vasilevskis, Lorraine C Mion
BACKGROUND: The ABCDE bundle is a multifaceted, interprofessional intervention that is associated with reduced ventilator and delirium days as well as increased likelihood of mobility in intensive care. OBJECTIVES: The aim of this study is to describe organizational domains that contribute to variation in ABCDE bundle implementation as reported by intensive care unit providers and to examine the capability of a conceptual framework for identifying variation in ABCDE bundle implementation...
November 2016: Dimensions of Critical Care Nursing: DCCN
Renee E Shimizu, Allan D Wu, Barbara J Knowlton
Effective learning results not only in improved performance on a practiced task, but also in the ability to transfer the acquired knowledge to novel, similar tasks. Using a modified serial reaction time (RT) task, the authors examined the ability to transfer to novel sequences after practicing sequences in a repetitive order versus a nonrepeating interleaved order. Interleaved practice resulted in better performance on new sequences than repetitive practice. In a second study, participants practiced interleaved sequences in a functional MRI (fMRI) scanner and received a transfer test of novel sequences...
October 17, 2016: Behavioral Neuroscience
Georges Jabbour, Pascale Mauriege, Denis Joanisse, Horia-Daniel Iancu
The purpose of this study was to evaluate the effects of 6 weeks of supramaximal exercise training (SET) on performance variables and metabolic changes in sedentary obese adults. Twenty-four obese adults were randomly allocated into a non-trained (NT) [n = 12; body mass index (BMI) = 33(3)] and SET group [n = 12; BMI = (33(2)]. After baseline metabolic and fitness measurements, the participants completed a 6-week SET intervention. Metabolic, anthropometric, and fitness assessments were repeated post-intervention...
October 15, 2016: Journal of Sports Sciences
Thomas Wyss, Maria Boesch, Lilian Roos, Céline Tschopp, Klaus M Frei, Hubert Annen, Roberto La Marca
BACKGROUND: Good physical fitness seems to help the individual to buffer the potential harmful impact of psychosocial stress on somatic and mental health. The aim of the present study is to investigate the role of physical fitness levels on the autonomic nervous system (ANS; i.e. heart rate and salivary alpha amylase) responses to acute psychosocial stress, while controlling for established factors influencing individual stress reactions. METHODS: The Trier Social Stress Test for Groups (TSST-G) was executed with 302 male recruits during their first week of Swiss Army basic training...
December 2016: Sports Medicine—Open
Daniela Bassi, Renata Gonçalves Mendes, Vivian Maria Arakelian, Flávia Cristina Rossi Caruso, Ramona Cabiddu, José Carlos Bonjorno Júnior, Ross Arena, Audrey Borghi-Silva
BACKGROUND: Concurrent aerobic and resistance training (CART) programs have been widely recommended as an important strategy to improve physiologic and functional performance in patients with chronic diseases. However, the impact of a personalized CART program in patients with type 2 diabetes (T2D) requires investigation. Therefore, the primary aim of the current study is to investigate the impact of CART programs on metabolic profile, glycemic control, and exercise capacity in patients with diabetes...
December 2016: Sports Medicine—Open
Baldwin Yeung, Philip Chiu, Anthony Teoh, Linfu Zheng, Shannon Chan, Kelvin Lam, Raymond Tang, Enders K W Ng
Background and study aims: Submucosal tunnelling endoscopic resection (STER) is a novel endoscopic technique to remove submucosal tumour (SMT). We propose a novel, low cost simulator for training of techniques for STER. Patients and methods: The model consisted of an ex-planted porcine oesophagus, stomach and duodenum with marbles embedded surgically in the submucosal plane. Two expert endoscopists with experience in submucosal tunnelling and 5 board-certified endoscopists with no experience in submucosal tunnelling were recruited...
October 2016: Endoscopy International Open
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