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https://www.readbyqxmd.com/read/29166449/caesarean-birth-rates-in-public-and-privately-funded-hospitals-a-cross-sectional-study
#1
Bruna Dias Alonso, Flora Maria Barbosa da Silva, Maria do Rosário Dias de Oliveira Latorre, Carmen Simone Grilo Diniz, Debra Bick
OBJECTIVE: To examine maternal and obstetric factors influencing births by cesarean section according to health care funding. METHODS: A cross-sectional study with data from Southeastern Brazil. Caesarean section births from February 2011 to July 2012 were included. Data were obtained from interviews with women whose care was publicly or privately funded, and from their obstetric and neonatal records. Univariate and multivariate analyses were conducted to generate crude and adjusted odds ratios (OR) with 95% confidence intervals (95%CI) for caesarean section births...
2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29165984/on-chip-lipid-extraction-using-super-absorbent-polymers-for-mass-spectrometry
#2
Geul Bang, Young Hwan Kim, Junghyo Yoon, Yeong Jun Yu, Seok Chung, Jeong Ah Kim
Pre-treatment of samples is the one of most important steps in analytical methods for efficient and accurate results. Typically, an extraction method used for lipid analysis with mass spectrometry is accompanied by complex liquid-liquid extraction. We have devised a simple, rapid, and efficient lipid extraction method using super absorbent polymers (SAPs) and developed a high-throughput lipid extraction platform based on a microfluidic system. Since SAPs can rapidly absorb an aqueous solution from a raw sample and convert it into the gel, the lipid extraction process can be remarkably simplified...
November 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29165629/morbidity-mortality-and-socioeconomics-in-females-with-46-xy-disorders-of-sex-development-a-nationwide-study
#3
Agnethe Berglund, Trine H Johannsen, Kirstine Stochholm, Mette H Viuff, Jens Fedder, Katharina M Main, Claus H Gravholt
Context: Little is known about long-term health outcomes in phenotypic females with 46,XY disorders of sex development (XY females) and the socioeconomic profile is not described in detail. Objective: To describe morbidity, mortality and socioeconomic status in XY females in a comparison to the general population. Design: A nationwide registry study with complete follow-up. Setting: A uniform public health care system...
November 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29165139/analysis-of-the-evidence-practice-gap-to-facilitate-proper-medical-care-for-the-elderly-investigation-using-databases-of-utilization-measures-for-national-database-of-health-insurance-claims-and-specific-health-checkups-of-japan-ndb
#4
Takeo Nakayama, Yuichi Imanaka, Yasushi Okuno, Genta Kato, Tomohiro Kuroda, Rei Goto, Shiro Tanaka, Hiroshi Tamura, Shunichi Fukuhara, Shingo Fukuma, Manabu Muto, Motoko Yanagita, Yosuke Yamamoto
As Japan becomes a super-aging society, presentation of the best ways to provide medical care for the elderly, and the direction of that care, are important national issues. Elderly people have multi-morbidity with numerous medical conditions and use many medical resources for complex treatment patterns. This increases the likelihood of inappropriate medical practices and an evidence-practice gap. The present study aimed to: derive findings that are applicable to policy from an elucidation of the actual state of medical care for the elderly; establish a foundation for the utilization of National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), and present measures for the utilization of existing databases in parallel with NDB validation...
June 6, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164997/where-policy-meets-practice-employer-perspectives-on-scheduling-and-hours-for-home-care-aides
#5
Elizabeth Nisbet, Jennifer Craft Morgan
In a context of growing demand for home-based direct care services, the need to retain direct care workers (DCWs) is clear. The Patient Protection and Affordable Care Act, changes to the Fair Labor Standards Act, and state-level changes in Medicaid support for home-based care together have affected agencies that hire DCWs, with implications for an issue that affects worker satisfaction: scheduling. Many home-based aides employed by agencies cannot count on consistent or sufficient hours. Hours shortfall and instability have been recognized as important issues for retail and restaurant workers, but focused on less for care aides...
November 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/29164091/review-of-the-campaign-to-prevent-falls-in-construction
#6
REVIEW
Kevin O'Donnell
Roofing is one of the most dangerous activities in the construction industry according to the US Bureau of Labor Statistics. Although injuries are manifold in this industry element, the vast majority of them occur as a result of falls from elevation (1, 2). These events lead to physical injury, fatalities, and financial burdens to the individual injured, their families, the employer, and the construction market as a whole (3, 4). In order to reduce construction worker falls, Occupational Health and Safety Administration launched the nationwide Campaign to Prevent Falls in Construction on April 26, 2012 (5)...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29164014/patient-communication-satisfaction-and-trust-before-and-after-use-of-a-standardized-birth-plan
#7
Clare-Marie Anderson, Rosie Monardo, Reni Soon, Jennifer Lum, Mary Tschann, Bliss Kaneshiro
The birth plan was developed as a way for pregnant women to communicate their desires and expectations for labor and delivery. Standardized birth plans have been used by some birth facilities as a communication tool. In this quality improvement project, we sought to describe communication, trust, and satisfaction scores after delivery in a group of patients who used a standardized birth plan. All pregnant women at 24 or more weeks of gestation were asked to complete a short, standardized birth plan. Communication, trust, and satisfaction were assessed before and after delivery...
November 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/29163023/perinatal-asphyxia-in-rat-alters-expression-of-novel-schizophrenia-risk-genes
#8
Alessandra Paparelli, Keiko Iwata, Tomoyasu Wakuda, Conrad Iyegbe, Robin M Murray, Nori Takei
Epidemiological studies suggest that obstetric complications, particularly those related to hypoxia during labor and delivery, are a risk factor for development of schizophrenia. The impact of perinatal asphyxia on postnatal life has been studied in a rodent model of global hypoxia, which is accompanied by cesarean section birth. This asphyxia model shows several behavioral, pharmacological, neurochemical, and neuroanatomical abnormalities in adulthood that have relevance to schizophrenia. Further, it is suggested that schizophrenia has a strong genetic component, and indeed novel candidate genes were recently identified by a genome-wide association study...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29163007/from-mice-to-mole-rats-species-specific-modulation-of-adult-hippocampal-neurogenesis
#9
Maria K Oosthuizen
Rodent populations living in their natural environments have very diverse ecological and life history profiles that may differ substantially from that of conventional laboratory rodents. Free-living rodents show species-specific neurogenesis that are dependent on their unique biology and ecology. This perspective aims to illustrate the benefit of studying wild rodent species in conjunction with laboratory rodents. African mole-rats are discussed in terms of habitat complexity, social structures, and longevity...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29162952/oral-health-status-and-fertility-treatment-including-ivf
#10
REVIEW
Sunali Sundeep Khanna, Prita A Dhaimade, Shalini Malhotra
Oral health is extremely important for the general wellbeing of the individual. From a number of research articles, it is established that there is a definitive connection between periodontal health and many systemic diseases, like type II diabetes, cardiovascular diseases and even preterm labor and low birth weight of babies. The significant rate of failure in the treatment of infertility and IVF (in vitro fertilization) even with multiple advancements in the last decade has made scientist take interest in newer parameters of health, an important one among them being periodontal health...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162743/akap95-mediated-nuclear-anchoring-of-pka-mediates-cortisol-induced-ptgs2-expression-in-human-amnion-fibroblasts
#11
Jiangwen Lu, Wangsheng Wang, Yabing Mi, Chuyue Zhang, Hao Ying, Luyao Wang, Yawei Wang, Leslie Myatt, Kang Sun
Phosphorylation of the transcription factors cyclic adenosine monophosphate response element-binding protein (CREB) and signal transducer and activator of transcription 3 (STAT3) by protein kinase A (PKA) is required for the cortisol-induced production of cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) in human amnion fibroblasts, which critically mediates human parturition (labor). We found that PKA was confined in the nucleus by A-kinase-anchoring protein 95 (AKAP95) in amnion fibroblasts and that this localization was key to the cortisol-induced expression of PTGS2, the gene encoding COX-2...
November 21, 2017: Science Signaling
https://www.readbyqxmd.com/read/29161301/detection-and-quantification-of-dengue-virus-using-a-novel-biosensor-system-based-on-dengue-ns3-protease-activity
#12
Ming-Shu Hsieh, Mei-Yu Chen, Chun-Hsiang Hsieh, Chien-Hsiung Pan, Guann-Yi Yu, Hsin-Wei Chen
BACKGROUND: The traditional methods, plaque assays and immuno-focus assays, used to titrate infectious dengue virus (DENV) particles are time consuming and labor intensive. Here, we developed a DENV protease activity detection system (DENPADS) to visualize DENV infection in cells based on dengue protease activity. METHODOLOGY/PRINCIPAL FINDINGS: Dengue NS3 protease cleaves NS4B-NS5. BHK-21 cells stably expressing the sensor module comprising DENV-2 NS4 and the 10 amino-terminal amino acids of NS5 (N10NS5) fused with the SV40 nuclear localization signal (NLS) and Cre recombinase (Cre), were generated...
2017: PloS One
https://www.readbyqxmd.com/read/29160483/nurses-in-the-labor-market-professional-insertion-competencies-and-skills
#13
Vilanice Alves de Araújo Püschel, Dafeni Costa, Priscila Patrício Reis, Larissa Bertacchini de Oliveira, Fábio da Costa Carbogim
OBJECTIVE: to characterize nurses graduated from the School of Nursing of the University of São Paulo, from 2006 to 2012; verify their entry, facilitating factors and difficulties of these graduates in the labor market and to consider their skills and competences in the world of work. METHOD: an exploratory, descriptive study with a qualitative approach. RESULTS: out of 505 graduates, 172 (34.1%) participated in the research. Entry into the labor market was mainly via public hospital institutions, in the SE of Brazil, in the caregiving sectors...
November 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29158339/genome-wide-mapping-of-decay-factor-mrna-interactions-in-yeast-identifies-nutrient-responsive-transcripts-as-targets-of-the-deadenylase-ccr4
#14
Jason E Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B Franklin Pugh, Joseph C Reese
The Ccr4-Not complex is a major regulator of stress responses that controls gene expression at multiple levels, from transcription to mRNA decay. Ccr4, a core subunit of the complex, is the main cytoplasmic deadenylase in Saccharomyces cerevisiae, however its mRNA targets have not been mapped on a genome-wide scale. Here we describe a genome-wide approach, RNA immunoprecipitation-high throughput sequencing (RIP-seq), to identify the RNAs bound to Ccr4, and two proteins that associate with it, Dhh1 and Puf5...
November 20, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29158159/on-the-distributional-and-evolutionary-nature-of-the-obesity-wage-penalty
#15
Christian Brown, P Wesley Routon
The economics literature supports a link between labor market measures, such as earnings, and health conditions, such as obesity. There is reason to believe the effects of obesity on wages may vary for high- and low-earning individuals and that obesity wage effects may evolve over a lifecycle or from generation to generation. Drawing on data from two longitudinal surveys, we estimate quantile and fixed effect quantile regressions, among others, to further examine the obesity wage effect. Results suggest an increasingly severe penalty across the wage distribution for females...
October 19, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/29157455/identification-of-preterm-birth-based-on-rqa-analysis-of-electrohysterograms
#16
Marta Borowska, Ewelina Brzozowska, Paweł Kuć, Edward Oczeretko, Romuald Mosdorf, Piotr Laudański
BACKGROUND AND OBJECTIVE: Common methods for data analysis are mainly based on linear concepts, but in recent years nonlinear dynamics methods have been introduced. It is a well-known fact that In typical biological systems lack of stationarity and rather sudden changes of state are the properties distinguishing them from each other. There is an urgent need to better understand the mechanical activity of the myometrium (its contractility) to find a solution for preterm delivery problem, the largest cause of neonatal deaths and morbidity...
January 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29156443/ensuring-quality-pharmacokinetic-analyses-in-antimicrobial-drug-development-programs
#17
REVIEW
Elizabeth A Lakota, Justin C Bader, Christopher M Rubino
Pharmacokinetic studies and analyses can be expensive, time consuming, and labor intensive. However, it is crucial to understand that much of what happens in antimicrobial drug development, such as dose-selection and clinical study design, can be optimized with a strong understanding of the underlying pharmacokinetics of an agent. In this way, pharmacokinetics forms the bedrock of a pharmacometric approach to antimicrobial development. Thus, pharmacokinetic analyses must be considered an integral part of a drug's development strategy and studies must be planned and designed accordingly...
November 17, 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29156436/impact-of-changes-in-labor-resources-and-transfers-of-land-use-rights-on-agricultural-non-point-source-pollution-in-jiangsu-province-china
#18
Hua Lu, Hualin Xie
This study systematically explores the likely mechanisms driving the effect of the transfer of agricultural land use rights (ALURs) on agricultural non-point source pollution (ANSP) in the context of changing agricultural labor resources. It quantitatively estimates the direction and degree of this influence from a microeconomic perspective using data from rural households. The results reveal that economies of scale caused by ALURs transfers contribute to reducing both the ANSP and marginal costs of inputs...
November 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29155794/an-array-based-comparative-genomic-hybridization-platform-for-efficient-detection-of-copy-number-variations-in-fast-neutron-induced-medicago-truncatula-mutants
#19
Yuhui Chen, Xianfu Wang, Shunfei Lu, Hongcheng Wang, Shibo Li, Rujin Chen
Mutants are invaluable genetic resources for gene function studies. To generate mutant collections, three types of mutagens can be utilized, including biological such as T-DNA or transposon, chemical such as ethyl methanesulfonate (EMS), or physical such as ionization radiation. The type of mutation observed varies depending on the mutagen used. For ionization radiation induced mutants, mutations include deletion, duplication, or rearrangement. While T-DNA or transposon-based mutagenesis is limited to species that are susceptible to transformation, chemical or physical mutagenesis can be applied to a broad range of species...
November 8, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155616/uncovering-the-power-of-personality-to-shape-income
#20
Jaap J A Denissen, Wiebke Bleidorn, Marie Hennecke, Maike Luhmann, Ulrich Orth, Jule Specht, Julia Zimmermann
The notion of person-environment fit implies that personal and contextual factors interact in influencing important life outcomes. Using data from 8,458 employed individuals, we examined the combined effects of individuals' actual personality traits and jobs' expert-rated personality demands on earnings. Results from a response surface analysis indicated that the fit between individuals' actual personality and the personality demands of their jobs is a predictor of income. Conclusions of this combined analysis were partly opposite to conclusions reached in previous studies using conventional regression methods...
November 1, 2017: Psychological Science
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