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Pattern hair loss

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https://www.readbyqxmd.com/read/28932068/familial-cicatricial-alopecia-report-of-familial-frontal-fibrosing-alopecia-and-fibrosing-alopecia-in-a-pattern-distribution
#1
Dandara Meurer Missio, Maria Fernanda Reis Gavazzoni Dias, Ralph Michel Trüeb
Frontal fibrosing alopecia (FFA) and fibrosing alopecia in a pattern distribution (FAPD) as originally reported by Kossard in 1994 and by Zinkernagel and Trüeb in 2000, respectively, represent two distinct patterns of cicatricial pattern hair loss. Both share a patterned distribution and histological evidence of a lichenoid follicular inflammation with fibrosis. FFA is characterized by a marginal alopecia along the frontotemporal hairline, and FAPD by a progressive alopecia of the centroparietal scalp. Since the original reports, evidence has accumulated that there exists considerable clinical overlap among FFA, FAPD, and lichen planopilaris, with coexistence of features of the three conditions within the same individual...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28932059/prevalence-of-nutritional-deficiencies-in-hair-loss-among-indian-participants-results-of-a-cross-sectional-study
#2
Dinesh Gowda, V Premalatha, D B Imtiyaz
BACKGROUND: Nutritional deficiencies are known to be associated with hair loss; however, the exact prevalence is not known. AIMS: The aim of this study is to evaluate the prevalence of nutritional deficiencies in participants with hair loss. MATERIALS AND METHODS: In this cross-sectional study, 100 enrolled participants were divided into telogen effluvium (TE), male-pattern hair loss (MPHL), and female-pattern hair loss (FPHL) based on the type of hair loss...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28932058/classification-of-male-pattern-hair-loss
#3
REVIEW
Christopher Toshihiro Wirya, Wenyu Wu, Kejia Wu
Male-pattern hair loss (MPHL) is a condition that affects the majority of men during adulthood. This condition is not life threatening but needs constant treatment and monitoring, especially in recent years where male appearance is gaining significant importance in society. An ideal classification with high amount of detail, practicality, and reproducibility is required to accurately diagnose and monitor this condition regularly and to assess the outcome of treatment. Numerous classifications have been invented, but many variants with different levels of detail, practicality, and reproducibility may cause confusion among clinicians...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28925723/expression-patterns-of-members-of-the-isocitrate-dehydrogenase-gene-family-in-murine-inner-ear
#4
Y-R Kim, K-H Kim, S Lee, S-K Oh, J-W Park, K-Y Lee, J-I Baek, U-K Kim
Age-related hearing loss (ARHL) is characterized by an age-dependent decline of auditory function characterized by with loss of sensory hair cells, spiral ganglion neurons, and stria vascularis (SV) cells in the cochlea of the inner ear. Aging and age-related diseases result from accumulated oxidative damage caused by reactive oxygen species (ROS) generated by mitochondria. The isocitrate dehydrogenase (IDH) family includes three enzymes in human cells: IDH1, IDH2, and IDH3. Although all three enzymes catalyze the same enzymatic reaction, that is, oxidative decarboxylation of isocitrate to produce α-ketoglutarate, each IDH enzyme has unique features...
September 19, 2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/28852294/a-spilt-head-study-of-efficacy-of-placebo-versus-platelet-rich-plasma-injections-in-the-treatment-of-androgenic-alopecia
#5
Dilip Kachhawa, Gauri Vats, Durgesh Sonare, Pankaj Rao, Sandeep Khuraiya, Rohit Kataiya
BACKGROUND: Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma with haemostatic and tissue repairing effects. Being enriched by various growth factors, PRP has become the focus of attention in numerous fields of medicine. Androgenic alopecia (AGA) is a common chronic hair loss disorder, characterised by progressive hair loss. Despite the therapeutic options available, there is low patient compliance and satisfaction rate...
April 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28838968/tbx1-and-jag1-act-in-concert-to-modulate-the-fate-of-neurosensory-cells-of-the-mouse-otic-vesicle
#6
Stephania Macchiarulo, Bernice E Morrow
The domain within the otic vesicle (OV) known as the neurosensory domain (NSD), contains cells that will give rise to the hair and support cells of the otic sensory organs, as well as the neurons that form the cochleovestibular ganglion (CVG). The molecular dynamics that occur at the NSD boundary relative to adjacent OV cells is not well defined. The Tbx1 transcription factor gene expression pattern is complementary to the NSD, and inactivation results in an expansion of the NSD and expression of the Notch ligand, Jag1 mapping, in part to the NSD...
August 24, 2017: Biology Open
https://www.readbyqxmd.com/read/28791288/a-practical-approach-to-the-diagnosis-and-management-of-hair-loss-in-children-and-adolescents
#7
REVIEW
Liwen Xu, Kevin X Liu, Maryanne M Senna
Hair loss or alopecia is a common and distressing clinical complaint in the primary care setting and can arise from heterogeneous etiologies. In the pediatric population, hair loss often presents with patterns that are different from that of their adult counterparts. Given the psychosocial complications that may arise from pediatric alopecia, prompt diagnosis and management is particularly important. Common causes of alopecia in children and adolescents include alopecia areata, tinea capitis, androgenetic alopecia, traction alopecia, trichotillomania, hair cycle disturbances, and congenital alopecia conditions...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28740409/hair-follicle-growth-by-stromal-vascular-fraction-enhanced-adipose-transplantation-in-baldness
#8
David Perez-Meza, Craig Ziering, Marcos Sforza, Ganesh Krishnan, Edward Ball, Eric Daniels
Great interest remains in finding new and emerging therapies for the treatment of male and female pattern hair loss. The autologous fat grafting technique is >100 years old, with a recent and dramatic increase in clinical experience over the past 10-15 years. Recently, in 2001, Zuk et al published the presence of adipose-derived stem cells, and abundant research has shown that adipose is a complex, biological active, and important tissue. Festa et al, in 2011, reported that adipocyte lineage cells support the stem cell niche and help drive the complex hair growth cycle...
2017: Stem Cells and Cloning: Advances and Applications
https://www.readbyqxmd.com/read/28728330/hair-diameter-variation-in-different-vertical-regions-of-the-occipital-safe-donor-area
#9
Seon Sik Yun, Jae Hyun Park, Young Cheon Na
BACKGROUND: Little is known concerning hair diameter variation within the safe donor area for hair transplantation surgery. Thicker or thinner hair may be needed, depending on the recipient area, hairline design, and the purpose of surgery. METHODS: Twenty-seven patients (7 men and 20 women; mean age, 28 years; range, 20-47 years) were included in this study. The midoccipital point was used as the reference point on the horizontal plane at the upper border of the helical rim...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28722458/-androgenetic-alopecia-in-women
#10
Jana Krabcová
Androgenetic alopecia is one of the most common diagnoses in a hair clinic. It is non-scarring pattern hair losses that affect individuals, independent on severity, age and gender. The incidence of AGA increases within the age. AGA affects women less frequently, is usually milder and is associated with diffuse thinning of the hair scalp. Prompt diagnosis and treatment are essential for obtaining optimal outcome.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28679963/transgenic-mice-display-hair-loss-and-regrowth-overexpressing-mutant-hr-gene
#11
Kuicheng Zhu, Cunshuan Xu, Jintao Zhang, Yingying Chen, Mengduan Liu
Mutations in the hairless (Hr) gene in both mice and humans have been implicated in the development of congenital atrichia, but the role of Hr in skin and hair follicle (HF) biology remains unknown. Here, we established transgenic mice (TG) overexpressing mutant Hr to investigate its specific role in the development of HF. Three transgenic lines were successfully constructed, and two of them (TG3 and TG8) displayed a pattern of hair loss and regrowth with alternation in the expression of HR protein. The mutant Hr gene inhibited the expression of the endogenous gene in transgenic individuals, which led to the development of alopecia...
July 5, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28668292/a-longitudinal-study-of-diurnal-cortisol-patterns-and-associated-factors-in-breast-cancer-patients-from-the-transition-stage-of-the-end-of-active-cancer-treatment-to-post-treatment-survivorship
#12
Fei-Hsiu Hsiao, Guey-Mei Jow, Wen-Hung Kuo, Ming-Yang Wang, King-Jen Chang, Yu-Ming Lai, Yu-Ting Chen, Chiun-Sheng Huang
OBJECTIVES: The aim of this study was to examine the changes in diurnal cortisol patterns and its associated factors among breast cancer patients over a 14-month follow up period. MATERIALS AND METHODS: A total of 85 breast cancer patients were recruited to participate in this study. Assessments were performed at baseline (T0), T1 (the 2nd month), T2 (the 5th month), T3 (the 8th month), and T4 (the 14th month). Salivary cortisol was measured and the following questionnaires were administered: BDI-II depression scale, European Organization for Research and Treatment of Cancer Core Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and its breast cancer-specific complementary measure (EORTC QLQ-BR23)...
June 28, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28618834/psychophysical-and-modeling-approaches-towards-determining-the-cochlear-phase-response-based-on-interaural-time-differences
#13
Hisaaki Tabuchi, Bernhard Laback
The cochlear phase response is often estimated by measuring masking of a tonal target by harmonic complexes with various phase curvatures. Maskers yielding most modulated internal envelope representations after passing the cochlear filter are thought to produce minimum masking, with fast-acting cochlear compression as the main contributor to that effect. Thus, in hearing-impaired (HI) listeners, reduced cochlear compression hampers estimation of the phase response using the masking method. This study proposes an alternative approach, based on the effect of the envelope modulation strength on the sensitivity to interaural time differences (ITDs)...
June 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28611622/psoriatic-alopecia-in-a-patient-with-systemic-lupus-erythematosus
#14
Wimolsiri Iamsumang, Tueboon Sriphojanart, Poonkiat Suchonwanit
Psoriasis is a chronic, recurrent, and relatively common inflammatory dermatologic condition, which demonstrates various clinical manifestations including hair loss. It was once believed that alopecia was not a presentation of scalp psoriasis, but it is now widely accepted that psoriatic alopecia exists. Although the majority of patients get hair regrowth, it can potentially lead to permanent hair loss. Herein, we report a case of 26-year-old female patient with systemic lupus erythematosus who presented with scalp hair loss and nonpruritic scaly plaques on the scalp...
January 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28589172/genome-wide-gene-expression-dataset-used-to-identify-potential-therapeutic-targets-in-androgenetic-alopecia
#15
R Dey-Rao, A A Sinha
The microarray dataset attached to this report is related to the research article with the title: "A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia" (Dey-Rao and Sinha, 2017) [1]. Male-pattern hair loss that is induced by androgens (testosterone) in genetically predisposed individuals is known as androgenetic alopecia (AGA). The raw dataset is being made publicly available to enable critical and/or extended analyses. Our related research paper utilizes the attached raw dataset, for genome-wide gene-expression associated investigations...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28566902/therapeutic-efficacy-of-a-combination-therapy-of-topical-17%C3%AE-estradiol-and-topical-minoxidil-on-female-pattern-hair-loss-a-noncomparative-retrospective-evaluation
#16
Sung Jay Choe, Solam Lee, Jaewoong Choi, Won-Soo Lee
BACKGROUND: A variety of agents have been used to treat female pattern hair loss (FPHL), including topical minoxidil, topical 17α-estradiol, oral anti-androgen agents, and mineral supplements. Compared with these single agent regimens, combination therapies could be a better therapeutic option in expectation of superior treatment outcome. OBJECTIVE: This study was designed to determine the efficacy of a combination therapy consisting of topical 0.025% 17α-estradiol and 3% minoxidil in Korean patients with FPHL...
June 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28526588/adam10-and-%C3%AE-secretase-regulate-sensory-regeneration-in-the-avian-vestibular-organs
#17
Mark E Warchol, Jennifer Stone, Matthew Barton, Jeffrey Ku, Rose Veile, Nicolas Daudet, Michael Lovett
The loss of sensory hair cells from the inner ear is a leading cause of hearing and balance disorders. The mammalian ear has a very limited ability to replace lost hair cells, but the inner ears of non-mammalian vertebrates can spontaneously regenerate hair cells after injury. Prior studies have shown that replacement hair cells are derived from epithelial supporting cells and that the differentiation of new hair cells is regulated by the Notch signaling pathway. The present study examined molecular influences on regeneration in the avian utricle, which has a particularly robust regenerative ability...
August 1, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28503741/the-effect-of-autologous-activated-platelet-rich-plasma-injection-on-female-pattern-hair-loss-a-randomized-placebo-controlled-study
#18
Abeer Attia Tawfik, Mai Abdel Raouf Osman
BACKGROUND: Hair is an essential part of a woman's appearance and attractiveness. This is reflected in the predominantly psychological morbidity that can be associated with female pattern hair loss. Platelet-rich plasma(PRP) has been used in numerous fields of medicine. Recently, PRP has received growing attention as a potential therapeutic tool for hair loss. OBJECTIVE: To evaluate the efficacy and safety of autologous platelet-rich plasma in the treatment of female pattern hair loss...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28502801/genome-wide-association-shows-that%C3%A2-pigmentation-genes-play-a-role-in-skin%C3%A2-aging
#19
Matthew H Law, Sarah E Medland, Gu Zhu, Seyhan Yazar, Ana Viñuela, Leanne Wallace, Sri Niranjan Shekar, David L Duffy, Veronique Bataille, Dan Glass, Tim D Spector, Diane Wood, Scott D Gordon, Julie M Barbour, Anjali K Henders, Alex W Hewitt, Grant W Montgomery, Richard A Sturm, David A Mackey, Adèle C Green, Nicholas G Martin, Stuart MacGregor
Loss of fine skin patterning is a sign of both aging and photoaging. Studies investigating the genetic contribution to skin patterning offer an opportunity to better understand a trait that influences both physical appearance and risk of keratinocyte skin cancer. We undertook a meta-analysis of genome-wide association studies of a measure of skin pattern (microtopography score) damage in 1,671 twin pairs and 1,745 singletons (N = 5,087) drawn from three independent cohorts. We identified that rs185146 near SLC45A2 is associated with a skin aging trait at genome-wide significance (P = 4...
September 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28492055/hormonal-therapy-in-female-pattern-hair-loss
#20
REVIEW
Kevin R Brough, Rochelle R Torgerson
No abstract text is available yet for this article.
March 2017: International Journal of Women's Dermatology
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