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Emmet Andrews

Jonathan A Silversides, Emmet Major, Andrew J Ferguson, Emma E Mann, Daniel F McAuley, John C Marshall, Bronagh Blackwood, Eddy Fan
BACKGROUND: It is unknown whether a conservative approach to fluid administration or deresuscitation (active removal of fluid using diuretics or renal replacement therapy) is beneficial following haemodynamic stabilisation of critically ill patients. PURPOSE: To evaluate the efficacy and safety of conservative or deresuscitative fluid strategies in adults and children with acute respiratory distress syndrome (ARDS), sepsis or systemic inflammatory response syndrome (SIRS) in the post-resuscitation phase of critical illness...
October 12, 2016: Intensive Care Medicine
Yuanyang Rong, Daping He, Adrian Sanchez-Fernandez, Craig Evans, Karen J Edler, Richard Malpass-Evans, Mariolino Carta, Neil B McKeown, Tomos J Clarke, Stuart H Taylor, Andrew J Wain, John M Mitchels, Frank Marken
Vacuum carbonization of organic precursors usually causes considerable structural damage and collapse of morphological features. However, for a polymer with intrinsic microporosity (PIM-EA-TB with a Brunauer-Emmet-Teller (BET) surface area of 1027 m(2)g(-1)), it is shown here that the rigidity of the molecular backbone is retained even during 500 °C vacuum carbonization, yielding a novel type of microporous heterocarbon (either as powder or as thin film membrane) with properties between those of a conducting polymer and those of a carbon...
November 10, 2015: Langmuir: the ACS Journal of Surfaces and Colloids
Noel P Lynch, Mark A Corrigan, David E Kearney, Emmet J Andrews
Obturator hernia is a rare pelvic hernia that occurs primarily in multiparous, elderly (>70 years of age), thin females. This case highlights the successful laparoscopic mesh repair of an incarcerated obturator hernia in an octogenarian. The authors report a case of an incarcerated obturator hernia in an elderly female with subsequent high-grade small bowel and its successful laparoscopic operative management. A review of the relevant literature was also performed following a search on the online literature databases such as PUBMED and EMBASE...
2013: Journal of Surgical Case Reports
Conor O'Shea, Denis Kelliher, Emmet Andrews, Mícheál O'Ríordáin, Michael O'Shea, Timothy Power, Pádraig Cantillon-Murphy
Laparoscopic colectomy is the gold standard in the treatment of malignant tumours arising in the mucosa of the colon wall. The procedure is performed under general endotracheal anaesthesia and involves establishing a pneumoperitoneum with the patient in the Trendelenburg position. However this position can cause anaesthetic difficulties due to excess blood flow to the head and neck, increased pressure on the diaphragm and increased venous pressure. In the absence of steep head-down positioning, the bowels fall or "spill" into the operating field, obstructing the surgical space...
September 2014: Annals of Biomedical Engineering
Abubakr Ahmed, Gaitri Sadadcharam, Emmet Andrews
INTRODUCTION: Changes in medical practice have promoted a culture of standardized care. Care pathways have been proven to raise the quality of clinical care. Their effect as an educational tool has not been evaluated to date. AIMS: To examine the educational role of care pathways in elective surgical admissions during surgical internship and the effect of their introduction on interns' confidence in performing tasks. METHODS: A questionnaire survey was filled in by interns to determine their confidence in performing different tasks during elective surgical admission and postoperative care...
March 2013: Journal of Surgical Education
Caitriona M Guinane, Amany Tadrous, Fiona Fouhy, C Anthony Ryan, Eugene M Dempsey, Brendan Murphy, Emmet Andrews, Paul D Cotter, Catherine Stanton, R Paul Ross
UNLABELLED: The human appendix has historically been considered a vestige of evolutionary development with an unknown function. While limited data are available on the microbial composition of the appendix, it has been postulated that this organ could serve as a microbial reservoir for repopulating the gastrointestinal tract in times of necessity. We aimed to explore the microbial composition of the human appendix, using high-throughput sequencing of the 16S rRNA gene V4 region. Seven patients, 5 to 25 years of age, presenting with symptoms of acute appendicitis were included in this study...
2013: MBio
Andrew L Samuelson, Maximilian Lee, Ahmad Kamal, Emmet B Keeffe, Aijaz Ahmed
BACKGROUND: Patients with diabetes mellitus overall experience worse health outcomes than non-diabetics, but whether this is true among recipients of liver transplantation still remains unclear. The aim of this study was to compare the mortality of diabetic and non-diabetic patients following liver transplantation. METHODS: We conducted a retrospective analysis of 530 adult patients undergoing liver transplantation at Stanford University Medical Center from February 1995 to July 2006...
July 2010: Digestive Diseases and Sciences
Hasan Al Chalabi, Dara O Kavanagh, Lana Hassan, Kate O Donnell, Emmeline Nugent, Emmet Andrews, Frank B V Keane, Diarmuid S O'Riordain, Andrew Miller, Paul Neary
BACKGROUND: Enhanced recovery programmes (ERPs) have demonstrated reduced morbidity and length of hospital stay in patients undergoing open elective colorectal resections. The application of laparoscopic techniques to colorectal surgery is associated with shorter length of stay and morbidity compared to open resections. In the setting of laparoscopic surgery, it is unclear whether there is an additive effect on length of stay and morbidity by combining these. The current study addresses the benefit of an ERP (RAPID protocol) in a cohort of matched patients undergoing laparoscopic sigmoid colon resection MATERIALS AND METHODS: Consecutive patients over a 40-month period who underwent laparoscopic sigmoid colon resection were assigned either to the RAPID protocol (group 1) or traditional post operative care (group 2) in a non-randomised manner...
June 2010: International Journal of Colorectal Disease
Jia-Xing Jiang, Fabing Su, Abbie Trewin, Colin D Wood, Hongjun Niu, James T A Jones, Yaroslav Z Khimyak, Andrew I Cooper
A series of rigid microporous poly(aryleneethynylene) (PAE) networks was synthesized by Sonogashira-Hagihara coupling chemistry. PAEs with apparent Brunauer-Emmet-Teller surface areas of more than 1000 m(2)/g were produced. The materials were found to have very good chemical and thermal stability and retention of microporosity under a variety of conditions. It was shown that physical properties such as micropore size, surface area, and hydrogen uptake could be controlled in a "quantized" fashion by varying the monomer strut length, as for metal-organic and covalent organic frameworks, even though the networks were amorphous in nature...
June 18, 2008: Journal of the American Chemical Society
Shane D Killeen, Emmet J Andrews, Henry P Redmond, Gregory J Fulton
BACKGROUND: Intuitively, vascular procedures performed by high-volume vascular subspecialists working at high-volume institutions should be associated with improved patient outcome. Although a large number of studies assess the relationship between volume and outcome, a single contemporary compilation of such studies is lacking. METHODS: A review of the English language literature was performed incorporating searches of the Medline, EMBASE, and Cochrane collaboration databases for abdominal aortic aneurysm repair (elective and emergent), carotid endarterectomy, and arterial lower limb procedures for any volume outcome relationship...
March 2007: Journal of Vascular Surgery
Vijayan Balan, David Schwartz, George Y Wu, Andrew J Muir, Reem Ghalib, John Jackson, Emmet B Keeffe, Lorenzo Rossaro, Alfreda Burnett, Betty L Goon, Peter J Bowers, Gerhard J Leitz et al.
OBJECTIVES: In hepatitis C virus (HCV)-infected patients receiving pegylated interferon (PEG-IFN)/ribavirin (RBV) combination therapy, anemia is a well-known side effect. The purpose of this study was to describe the time course and extent of hemoglobin (Hb) changes and the erythropoietic response to PEG-IFN/RBV-induced anemia. METHODS: In this multicenter, observational, 8-wk study, laboratory parameters were measured weekly for 8 wk or until early withdrawal. Primary endpoints included changes in Hb and serum erythropoietin (sEPO) from baseline to week 8; other measures were changes in reticulocytes and RBV dose...
February 2005: American Journal of Gastroenterology
Conor J Shields, Desmond C Winter, Jiang Huai Wang, Emmet Andrews, Walter E Laug, H Paul Redmond
BACKGROUND: Hypertonic saline infusion dampens inflammatory responses and suppresses neutrophil-endothelial interaction by reducing adhesion molecule expression. This study tested the hypothesis that hypertonic saline attenuates tumor cell adhesion to the endothelium through a similar mechanism. METHODS: Human colon cancer cells (LS174T) were transfected with green fluorescent protein and exposed to lipopolysaccharide, tumor necrosis factor-alpha, and interleukin-6 under hypertonic and isotonic conditions for 1 and 4 hours...
July 2004: Surgery
Emmet Andrews, B C Ramesh, L Nölke, H P Redmond, T Aherne, A O'Donnell
Insertion of a chest drain can be associated with serious complications. It is recommended that the drain is inserted with blunt dissection through the chest wall but there is no specific instrument to aid this task. We describe a new reusable forceps that has been designed specifically to facilitate the insertion of chest drains.A feasibility study of its use in patients who required a chest drain as part of elective cardiothoracic operations was undertaken. The primary end-point was successful and accurate placement of the drain...
December 2003: Injury
Andrew B Nevins, Emmet B Keeffe
Acute pancreatitis is a well-recognized complication of endoscopic retrograde cholangiopancreatography but is not considered to be a complication associated with other endoscopic procedures. We present a case of acute pancreatitis that occurred after uneventful upper and lower gastrointestinal endoscopy. The temporal relationship of the endoscopic procedures and development of acute pancreatitis suggests a causal relation. Furthermore, the patient had none of the usual etiologic factors associated with pancreatitis, i...
January 2002: Journal of Clinical Gastroenterology
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