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https://www.readbyqxmd.com/read/27928851/efficacy-of-a-single-40-mg-intravenous-dose-of-parecoxib-for-postoperative-pain-control-after-elective-cesarean-delivery-a-double-blind-randomized-placebo-controlled-trial
#1
Nittaya Inthigood, Tripop Lertbunnaphong, Atthapon Jaishuen
AIM: The aim of this study was to determine the efficacy of a single 40-mg intravenous (i.v.) dose of parecoxib as an adjunctive analgesia to intrathecal morphine after elective cesarean delivery (CD). METHODS: A total of 82 low-risk term pregnant women who were scheduled for elective CD during the June 2014-June 2015 study period were enrolled. Two hours after surgery, subjects were randomly assigned to receive either i.v. injection of 2 mL (40 mg) parecoxib (study group; n = 41) or 2 mL normal saline solution (control group; n = 41)...
December 8, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27924205/risperidone-in-a-child-with-untractable-emergency-delirium-a-case-report
#2
Young Hee Shin, Seung Hyeon Lee, Dae Yoon Kim
A 6-year-old boy was scheduled for thoracic magnetic resonance imaging under deep sedation with midazolam 1.8 mg and propofol 100 µg/kg/min via intravenous injection. He showed emergence delirium in the post-anesthesia care unit. The staff attempted to calm him by administering flumazenil as an antidote for midazolam, propofol for further sedation, and meperidine. However, this was not successful. A psychiatrist recommended the use of antipsychotics. Administration of risperidone led to immediate resolution of the boy's symptoms and relaxed him...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27924202/randomized-trial-of-subfascial-infusion-of-ropivacaine-for-early-recovery-in-laparoscopic-colorectal-cancer-surgery
#3
Sang Hyun Lee, Woo-Seog Sim, Go Eun Kim, Hee Cheol Kim, Joo Hyun Jun, Jin Young Lee, Byung-Seop Shin, Heejin Yoo, Sin-Ho Jung, Joungyoun Kim, Seung Hyeon Lee, Deok Kyu Yo, Yu Ri Na
BACKGROUND: There is a need for investigating the analgesic method as part of early recovery after surgery tailored for laparoscopic colorectal cancer (LCRC) surgery. In this randomized trial, we aimed to investigate the analgesic efficacy of an inverse 'v' shaped bilateral, subfascial ropivacaine continuous infusion in LCRC surgery. METHODS: Forty two patients undergoing elective LCRC surgery were randomly allocated to one of two groups to receive either 0.5% ropivacaine continuous infusion at the subfascial plane (n = 20, R group) or fentanyl intravenous patient controlled analgesia (IV PCA) (n = 22, F group) for postoperative 72 hours...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27856931/5-ht3-receptor-antagonists-for-the-prevention-of-postoperative-shivering-a-meta-analysis
#4
Chengmao Zhou, Yu Zhu, Zhen Liu, Lin Ruan
OBJECTIVE: We evaluated the efficacy of 5-HT3 receptor antagonists for the prevention of postoperative shivering. METHODS: We searched PubMed, the Cochrane Library, EMBASE and Web of Knowledge to find randomized controlled trials (RCT) of 5-HT3 receptor antagonists for the prevention of postoperative shivering. Two researchers independently screened studies, extracted data, and assessed quality in accordance with the inclusion and exclusion criteria, and then conducted a meta-analysis using RevMan 5...
November 17, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27847695/combined-ketamine-tramadol-subcutaneous-wound-infiltration-for-multimodal-postoperative-analgesia-a-double-blinded-randomized-controlled-trial-after-renal-surgery
#5
Mohammad Reza Khajavi, Marzieh Navardi, Reza Shariat Moharari, Pejman Pourfakhr, Narjes Khalili, Farhad Etezadi, Farsad Imani
BACKGROUND: Pain is an important consideration after renal surgery. A multimodal approach to postoperative pain management could enhance analgesia by risking fewer side effects after surgery. OBJECTIVES: The aim of this study was to evaluate the clinical efficacy of the subcutaneous infiltration of ketamine and tramadol at the incision site to reduce postoperative pain. METHODS: Sixty-four patients between 18 and 80 years old who were scheduled for elective renal surgery were enrolled in a double-blind randomized controlled study...
October 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27833499/anesthesia-in-a-child-with-kinsbourne-syndrome-does-anesthesia-technique-matters
#6
N Nisa, P Talawar, B Vasudevan
Kinsbourne syndrome is a rare neurological paraneoplastic syndrome associated with neuroblastic tumors. There are very few literatures on its anesthetic management and interaction with anesthetic agents. The epileptogenic potential of certain anesthetic agents such as ketamine, etomidate, and meperidine might trigger opsoclonus and myoclonus and have an impact on the long-term neurological outcome. The objective of this case report is to discuss the safety of anesthetic agents and their relationship in a patient with Kinsbourne syndrome...
October 2016: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/27829941/a-comparison-of-propofol-and-midazolam-meperidine-sedation-in-upper-gastrointestinal-endoscopy
#7
Sinan Uzman, Bunyamin Gurbulak, Esin Kabul Gurbulak, Turgut Donmez, Adnan Hut, Dogan Yildirim
INTRODUCTION: There is increasing interest in sedation for upper gastrointestinal endoscopy (UGE). Prospective randomized studies comparing sedation properties and complications of propofol and midazolam/meperidine in upper gastrointestinal endoscopy (UGE) are few. AIM: To compare propofol and midazolam/meperidine sedation for UGE in terms of cardiopulmonary side effects, patient and endoscopist satisfaction and procedure-related times. MATERIAL AND METHODS: This was a prospective, randomized, double-blind study of propofol versus midazolam and meperidine in 100 patients scheduled for diagnostic upper gastrointestinal endoscopy...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/27756210/prevalence-associated-factors-and-treatment-of-post-spinal-shivering-in-a-sub-saharan-tertiary-hospital-a-prospective-observational-study
#8
Tonny Stone Luggya, Richard Nicholas Kabuye, Cephas Mijumbi, Joseph Bahe Tindimwebwa, Andrew Kintu
BACKGROUND: Surgery and anaesthesia cause shivering due to thermal dysregulation as a compensatory mechanism and is worsened by vasodilatation from spinal anaesthesia that redistributes core body heat. Due to paucity of data Mulago Hospital's post spinal shivering burden is unknown yet it causes discomfort and morbidity. METHODS: Ethical approval was obtained to perform the study among consenting mothers due for elective caesarean section from March to May 2011...
October 18, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27687359/a-comparison-of-prophylactic-use-of-meperidine-meperidine-plus-dexamethasone-and-ketamine-plus-midazolam-for-preventing-of-shivering-during-spinal-anesthesia-a-randomized-double-blind-placebo-controlled-study
#9
Ali Solhpour, Alireza Jafari, Masoud Hashemi, Behnam Hosseini, Sajad Razavi, Gholamreza Mohseni, Maryam Vosoughian, Faranak Behnaz, Reza Amin Nejad, Mohamad Amin Pourhoseingholi, Fereshteh Soltani
STUDY OBJECTIVES: The aim of this study is to compare the efficacy of combination of meperidine and dexamethasone with that of placebo, meperidine alone, and the combination of ketamine and midazolam in preventing shivering during spinal anesthesia. DESIGN: This is a prospective, placebo-controlled study. SETTING: The setting is at an operating room of a university-based teaching hospital. PATIENTS: Two hundred American Society of Anesthesiologists I and II patients undergoing orthopedic and urologic surgery under spinal anesthesia were included...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27632391/meta-analysis-of-randomized-controlled-trials-on-the-efficacy-and-safety-of-ondansetron-in-preventing-postanesthesia-shivering
#10
Min Li, Xiaolan Hu, Yuan Tan, Baoping Yang, Kun Li, Zhenyu Tang
OBJECTIVES: Considerable controversy exists regarding the efficacy of ondansetron in preventing postanesthesia shivering (PAS). We performed a meta-analysis of randomized controlled trials to examine the controversy. MATERIALS AND METHODS: Randomized controlled trials assessing the effect of ondansetron on the prevention of PAS were identified from electronic databases (PubMed and EMBASE). The meta-analysis was performed with the fixed-effect model or random-effect model according to heterogeneity...
September 12, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27623143/trends-in-the-distribution-of-opioids-in-puerto-rico-1999-2013
#11
Sausan El Burai Félix, Karin A Mack, Christopher M Jones
OBJECTIVE: Limited information has been published about opioid prescribing practices in Puerto Rico. The objective of this study was to create baseline trends of opioids distributed over a period of fourteen years in Puerto Rico. METHODS: We examined data from the U.S. Drug Enforcement Administration's Automation of Reports and Consolidated Orders System (ARCOS) for the period 1999-2013. ARCOS data reflects the amount of controlled substances legally dispensed. Analyses include the distribution of opioids (in morphine milligram equivalent kg per 10,000 persons) by year and entity (pharmacy, hospital, practitioner)...
September 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27622717/systematic-quality-assessment-of-published-antishivering-protocols
#12
Ko-Eun Choi, Bomi Park, Asma M Moheet, Amanda Rosen, Shouri Lahiri, Axel Rosengart
Shivering is a common side effect of targeted temperature modulation and general anesthesia. Antishivering strategies often employ a stepwise approach involving both pharmacological and physical interventions. However, approaches to treat shivering are often empiric and vary widely across care environments. We evaluated the quality of published antishivering protocols and guidelines with respect to methodological rigor, reliability, and consistency of recommendations. Using 4 medical databases, we identified 4027 publications that addressed shivering therapy, and excluded 3354 due to lack of relevance...
September 12, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27621675/meperidine-pethidine-versus-morphine-in-acute-pain-management-of-opioid-dependent-patients
#13
Hassan Solhi, Hossein Sanaei-Zadeh, Sadra Solhi, Mohammad Ali Azizi Nadian, Morteza Gharibi, Bahman Sadeghi Sedeh
The present study aimed to evaluate the effectiveness of morphine and meperidine (pethidine) as pain relief in opioid-dependent patients with acute pain. A total of 122 opioid-dependent patients with acute pain were included in the study. Their pain severity was assessed, using visual analog scale (VAS) scores ranging from 0 to 10. The patients randomly received intravenous morphine (up to 0.15 mg/kg) or meperidine (up to 1.5 mg/kg) for pain control by patient control analgesia (PCA) pump. The clinical opioid withdrawal scale (COWS) was employed for the assessment of withdrawal symptoms...
2016: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/27569734/sedation-and-use-of-analgesics-in-endoscopic-retrograde-cholangiopancreatography-a-double-blind-comparison-study-of-meperidine-midazolam-remifentanil-midazolam-and-remifentanil-alone
#14
Jinhua Zhang, Yong Huang, Zhao Li, Jian Li, Kunpeng Liu, Chenghui Li
PURPOSE: To compare the efficacy and remifentanil with midazolam for conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS: 99 patients scheduled for ERCP were randomly allocated to be treated with either meperidine/midazolam (group C, n = 33), remifentanil (group R, n = 33), or the remifentanil plus midazolam (group RM, n = 33). In group C, intermittent intravenous meperidine and midazolam were administrated during the procedure; in group R, remifentanil was infused continuously at a rate of 0...
November 2016: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27562966/lc-ms-ms-method-for-the-analysis-of-miscellaneous-drugs-in-wastewater-during-football-games-iii
#15
Brandon Stamper, Waseem Gul, Murrell Godfrey, Shahbaz W Gul, Mahmoud A ElSohly
Continuing our previous studies analyzing drugs of abuse in municipal wastewater, a method was developed for the analysis of miscellaneous drugs of abuse in wastewater samples using liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS). Eight drugs and metabolites were analyzed including 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrolidine (EDDP), fentanyl, norfentanyl, meperidine, normeperidine, methadone, phencyclidine and tramadol. These drugs were chosen because of their widespread abuse. Wastewater samples were collected at both the Oxford Waste Water Treatment Plant in Oxford, Mississippi (MS) and the University Wastewater Treatment Plant in University, MS...
October 2016: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/27547232/effects-of-electroacupuncture-on-pain-threshold-of-laboring-rats-and-the-expression-of-norepinephrine-transporter-and-%C3%AE-2-adrenergic-receptor-in-the-central-nervous-system
#16
Qianli Tang, Qiuyan Jiang, Suren R Sooranna, Shike Lin, Yuanyuan Feng, Qi Zhang, Meili Wang, Yu Wang
To observe the effects of electroacupuncture on pain threshold of laboring rats and the expression of norepinephrine transporter and α2 adrenergic receptor in the central nervous system to determine the mechanism of the analgesic effect of labor. 120 pregnant rats were divided into 6 groups: a control group, 4 electroacupuncture groups, and a meperidine group. After interventions, the warm water tail-flick test was used to observe pain threshold. NE levels in serum, NET, and α2AR mRNA and protein expression levels in the central nervous system were measured...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27509828/meperidine-induced-qtc-interval-prolongation-prevalence-risk-factors-and-correlation-to-plasma-drug-and-metabolite-concentrations%C3%A2
#17
Guillermo Alberto Keller, María Cecilia Villa Etchegoyen, Nicolás Fernández, Nancy Mónica Olivera, Patricia Noemí Quiroga, Roberto Alejandro Diez, Guillermo Di Girolamo
: A prolongation of the QTc-interval has been described for several opioids, including pethidine (meperidine). OBJECTIVE: To evaluate in the clinical setting the frequency and risk factors associated with the QT-interval prolongation induced by meperidine. RESEARCH DESIGN AND METHODS: We recruited patients requiring meperidine administration and recorded their medical history and comorbidities predisposing to QT-interval prolongation. Ionograms and electrocardiograms (ECGs) were performed at baseline and during treatment; QT was corrected using the Bazzet, Fridericia, Framinghan, and Hogdes formulas...
August 11, 2016: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27465337/effect-of-preemptive-ketamine-administration-on-postoperative-visceral-pain-after-gynecological-laparoscopic-surgery
#18
Hong-Qi Lin, Dong-Lin Jia
The pain following gynecological laparoscopic surgery is less intense than that following open surgery; however, patients often experience visceral pain after the former surgery. The aim of this study was to determine the effects of preemptive ketamine on visceral pain in patients undergoing gynecological laparoscopic surgery. Ninety patients undergoing gynecological laparoscopic surgery were randomly assigned to one of three groups. Group 1 received placebo. Group 2 was intravenously injected with preincisional saline and local infiltration with 20 mL ropivacaine (4 mg/mL) at the end of surgery...
August 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27451091/similar-risk-of-cardiopulmonary-adverse-events-between-propofol-and-traditional-anesthesia-for-gastrointestinal-endoscopy-a-systematic-review-and-meta-analysis
#19
Vaibhav Wadhwa, Danny Issa, Sushil Garg, Rocio Lopez, Madhusudhan R Sanaka, John J Vargo
BACKGROUND & AIMS: Even though propofol use for gastrointestinal endoscopic procedures has increased over the past decade, there is a perception that it causes a higher rate of cardiopulmonary adverse events. The aim of this study was to compare the sedation-related adverse events associated with use of propofol vs nonpropofol agents for endoscopic procedures. We also wanted to determine the influence of duration or complexity of the procedures and endoscopist-directed (gastroenterologist) vs non-gastroenterologist-directed sedation on the outcomes...
July 21, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27366504/the-incidence-of-delirium-at-the-postoperative-intensive-care-unit-in-adult-patients
#20
Emel Ünal Bilge, Menşure Kaya, Gülçin Özalp Şenel, Süheyla Ünver
OBJECTIVE: In this study, we aimed to determine the risk factors and the incidence of delirium in patients who were followed postoperatively in our surgical intensive care unit for 24 h using the confusion assessment method (CAM). METHODS: After obtaining approval from the ethics committee, 250 patients were included in the study. Patients who were operated under general anaesthesia or regional anaesthesia and followed in the surgical intensive care unit were evaluated by the Ramsay Sedation Scale on the first postoperative day...
August 2015: Turkish Journal of Anaesthesiology and Reanimation
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