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https://www.readbyqxmd.com/read/29760569/concomitant-use-of-opioid-medications-with-triptans-or-serotonergic-antidepressants-in-us-office-based-physician-visits
#1
Kyle C Molina, Kathleen A Fairman, David A Sclar
Background: Opioids are not recommended for routine treatment of migraine because their benefits are outweighed by risks of medication overuse headache and abuse/dependence. A March 2016 US Food and Drug Administration (FDA) safety communication warned of the risk of serotonin syndrome from using opioids concomitantly with 5-hydroxytryptamine receptor agonists (triptans) or serotonergic antidepressants: selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs)...
2018: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/29756066/postanaesthetic-shivering-from-pathophysiology-to-prevention
#2
REVIEW
Maria Bermudez Lopez
Postoperative shivering is a common complication of anaesthesia. Shivering is believed to increase oxygen consumption, increase the risk of hypoxemia, induce lactic acidosis, and catecholamine release. Therefore, it might increase the postoperative complications especially in high-risk patients. Moreover, shivering is one of the leading causes of discomfort for postsurgical patients. Shivering is usually triggered by hypothermia. However, it occurs even in normothermic patients during the perioperative period...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29732033/comparison-of-preemptive-effect-of-intravenous-ketorolac-versus-meperidine-on-postoperative-shivering-and-pain-in-patients-undergoing-cesarean-section-under-spinal-anesthesia-a-prospective-randomized-double-blind-study
#3
Marzieh Beigom Khezri, Maryam Al-Sadat Mosallaei, Mehdi Ebtehaj, Navid Mohammadi
Background: Pain and shivering are two unpleasant problems in postoperative period. Various techniques are used to alleviate the postoperative shivering and pain. We compared the preemptive prescription of a single dose of intravenous meperidine and ketorolac on postoperative pain and shivering in patients undergoing cesarean section with spinal anesthesia. Methods: One hundred and fifty patients who were scheduled for elective cesarean section under spinal anesthesia were randomly allocated to one of three study groups to receive intravenous ketorolac (group K), meperidine (group M) or normal saline (group P)...
2018: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29723643/transvaginal-natural-orifice-transluminal-endoscopic-surgery-for-female-to-male-transgender-men
#4
Yi-Le Lee, Teh-Fu Hsu, Ling-Yu Jiang, Hsiang-Tai Chao, Peng-Hui Wang, Yi-Jen Chen
STUDY OBJECTIVE: Previous studies suggest female-to-male transgender men tend to choose less invasive procedures, but the superior route of hysterectomy for them remains undetermined. DESIGN: Retrospective study (Canadian Task Force Classification II-3) SETTING: Academic tertiary hospital PATIENTS: Fifty-six female-to-male transsexuals received total vaginal hysterectomy (VH) with bilateral salpingo-oophorectomy (BSO) between April 2008 and August 2016 at Taipei Veterans General Hospital...
April 30, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29714490/efficacy-of-ketamine-in-pediatric-sedation-dentistry-a-systematic-review
#5
Samuel Oh, Karl Kingsley
BACKGROUND: Ketamine has been used as a safe and effective sedative to treat adults and children exhibiting high levels of anxiety or fear during dental treatment. Pediatric dentistry often involves patients with high levels of anxiety and fear and possibly few positive dental experiences. Patient management can involve behavioral approaches, as well as the use of sedation or general anesthesia with a variety of agents, including midazolam, diazepam, hydroxyzine, meperidine, and ketamine...
May 2018: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29618226/the-effect-of-rectus-muscle-re-approximation-at-cesarean-delivery-on-pain-perceived-after-operation-a-randomized-control-trial
#6
Eman F Omran, Hadeer Meshaal, Sarah M Hassan, Amira S Dieb, Hala Nabil, Hani Saad
BACKGROUND: Cesarean section rate has increased dramatically worldwide but there is still debate about the optimum operative technique of cesarean section. OBJECTIVE: The purpose of this study was to assess the effect of rectus muscle reapproximation at cesarean delivery on the postoperative pain. METHODS: This study was a prospective, double-blind, randomized controlled trial. It included 280 primigravidas, with a singleton pregnancy, who underwent elective lower segment cesarean section at term...
April 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29608639/transition-to-nonopioid-analgesia-does-not-impair-pain-control-after-major-aesthetic-plastic-surgery
#7
Thu-Hoai C Nguyen, Nicholas F Lombana, Dmitry Zavlin, Clayton L Moliver
Background: Multimodal analgesic protocols are increasingly favored over traditional opioid regimens due to decreased adverse side effects and reduced opioid consumption. Concomitant use of selective cyclooxygenase (COX)-2 inhibitor celecoxib and anticonvulsant gabapentin have been proposed to adequately control acute postoperative pain. Objectives: To determine efficacy of postoperative pain control using nonopioid pain regimen vs traditional opioids for all aesthetic plastic surgery procedures...
March 28, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29605659/interscalene-brachial-plexus-bolus-block-versus-patient-controlled-interscalene-indwelling-catheter-analgesia-for-the-first-48-hours-after-arthroscopic-rotator-cuff-repair
#8
Jong-Ho Kim, Hyun Jung Koh, Dong Kyu Kim, Hyo-Jin Lee, Ki-Hyun Kwon, Kwang-Yeol Lee, Yang-Soo Kim
BACKGROUND: We sought to compare the efficacy of interscalene brachial plexus bolus blockade (IBPBB) and patient-controlled interscalene indwelling catheter analgesia (PCIA) for postoperative pain management within 48 hours postoperatively in patients undergoing arthroscopic rotator cuff repairs (ARCR). METHODS: Patients undergoing ARCR were randomized into 3 groups by postoperative analgesia method. The IBPBB group received a mixed solution of 16 mL of 0.75% ropivacaine and 4 mL of 2% lidocaine as a bolus postoperatively...
March 29, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29576175/50-years-ago-in-the-journal-of-pediatrics-the-effect-of-pretreatment-with-pentobarbital-meperidine-or-hyperbaric-oxygen-on-the-response-to-anoxia-and-resuscitation-in-newborn-rabbits
#9
https://www.readbyqxmd.com/read/29551331/trends-in-medical-use-of-opioids-in-the-u-s-2006-2016
#10
Brian J Piper, Dipam T Shah, Olapeju M Simoyan, Kenneth L McCall, Stephanie D Nichols
INTRODUCTION: The U.S. is experiencing an opioid epidemic which is at least partially iatrogenic and fueled by both prescription and illicit misuse. This study provides a nationwide examination of opioid distribution patterns during the last decade. METHODS: Data were obtained from the U.S. Drug Enforcement Administration's Automation of Reports and Consolidated Orders System for 2006-2016. Analyses include quantities of ten opioids legally dispensed nationwide by weight and converted to Morphine Milligram Equivalents...
March 9, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29506986/opioid-prescribing-and-adverse-events-in-opioid-naive-patients-treated-by-emergency-physicians-versus-family-physicians-a-population-based-cohort-study
#11
Bjug Borgundvaag, Shelley McLeod, Wayne Khuu, Catherine Varner, Mina Tadrous, Tara Gomes
BACKGROUND: Emergency physicians provide primary care to patients and often prescribe opioids for acutely painful self-limiting conditions. The objective of this study was to describe patterns of opioid prescribing by emergency physicians and family physicians and to explore the relation between setting of initiation of opioid treatment and adverse events over the subsequent 2 years. METHODS: This was a population-based cohort study using administrative data from Ontario...
March 1, 2018: CMAJ Open
https://www.readbyqxmd.com/read/29466048/effects-of-dexmedetomidine-combined-with-commonly-administered-opioids-on-clinical-variables-in-dogs
#12
Lilian T Nishimura, Adam Auckburally, Juliana Santilli, Beatriz H B Vieira, Debora O Garcia, Cristiane S Honsho, Ewaldo de Mattos-Junior
OBJECTIVE To evaluate cardiopulmonary, sedative, and antinociceptive effects of dexmedetomidine combined with commonly administered opioids in dogs. ANIMALS 8 healthy Beagles. PROCEDURES Dogs were sedated by IM administration of each of 7 treatments. Treatments comprised dexmedetomidine (0.01 mg/kg; Dex) and the same dose of dexmedetomidine plus butorphanol (0.15 mg/kg; Dex-But), meperidine (5 mg/kg; Dex-Mep), methadone (0.5 mg/kg; Dex-Meth), morphine (0.5 mg/kg; Dex-Mor), nalbuphine (0.5 mg/kg; Dex-Nal), or tramadol (5 mg/kg; Dex-Tram)...
March 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29335074/trends-in-narcotics-and-sedative-use-during-mechanical-ventilation-of-preterm-infants-in-canadian-neonatal-intensive-care-units
#13
(no author information available yet)
OBJECTIVE: Mechanical ventilation (MV) in preterm infants (PTI) causes discomfort. Whether it causes pain is controversial. Meta analysis reviews of published work on PTI during MV have shown no clinically significant impact of opioids on pain scales, and hence not recommended for routine use in neonatal intensive care units (NICUs). Similarly regular use of sedative midazolam is also not recommended. Therefore we hypothesized a downward trend in narcotics and sedatives used in MV of PTI in NICUs...
January 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29201800/effect-of-different-sedation-regimes-on-cognitive-functions-in-colonoscopy
#14
Perihan Ekmekçi, Gulbanu Erkan, Hakan Yilmaz, Baturay K Kazbek, Ulku C Köksoy, Güler Doganay, Doganay Filiz Tüzüner
Aim: To compare the effects of propofol/remifentanil and meperidine/midazolam on postprocedure cognitive function. Materials and methods: A total of 100 American Society of Anesthesiologists (ASA) score I to III patients undergoing elective colonoscopy were taken into the study and divided into two groups. Exclusion criteria were patient refusal, mini mental test (MMT) <26, The Amsterdam Preoperative Anxiety and Information Scale (APAIS) >10, advanced cardiopulmonary or psychiatric disease, chronic alcohol abuse, morbid obesity, and known allergy to study drugs...
July 2017: Euroasian journal of hepato-gastroenterology
https://www.readbyqxmd.com/read/29201797/effectiveness-of-sedoanalgesia-in-percutaneous-liver-biopsy-premedication
#15
Orhan Sezgin, Serkan Yaras, Fehmi Ates, Engin Altintas, Bunyamin Saritas
Aim: Percutaneous needle liver biopsy (PLB) is frequently associated with pain and anxiety. This may discourage the patients for biopsy, and rebiopsies, if needed. We planned a study to investigate the efficacy of additional analgesia or sedation for PLB. Materials and methods: The study has been designed as a single-center, prospective study. The PLB was planned for 18- to 65-year-old consecutive patients who were included in the study. The patients were divided into three premedication groups as control, Meperidine, and Midazolam...
July 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29127294/preventing-shivering-with-adjuvant-low-dose-intrathecal-meperidine-a-meta-analysis-of-randomized-controlled-trials-with-trial-sequential-analysis
#16
Yu-Cih Lin, Chien-Yu Chen, Yuan-Mei Liao, Alan Hsi-Wen Liao, Pi-Chu Lin, Chuen-Chau Chang
The aim of this systematic review and meta-analysis is to evaluate the pros and cons of adjuvant low dose intrathecal meperidine for spinal anaesthesia. We searched electronic databases for randomized controlled trials using trial sequential analysis (TSA) to evaluate the incidence of reduced rescue analgesics, shivering, pruritus, nausea and vomiting when applying adjuvant intrathecal meperidine. Twenty-eight trials with 2216 patients were included. Adjuvant intrathecal meperidine, 0.05-0.5 mg kg-1 , significantly reduced incidence of shivering (relative risk, RR, 0...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29108129/simultaneous-quantitation-of-meperidine-normeperidine-tramadol-propoxyphene-and-norpropoxyphene-in-human-plasma-using-solid-phase-extraction-and-gas-chromatography-mass-spectrometry-method-validation-and-application-to-cardiovascular-safety-of-therapeutic-doses
#17
Nicolás Fernández, Nancy Mónica Olivera, Guillermo Alberto Keller, Roberto Alberto Diez, Guillermo Di Girolamo, Patricia Noemí Quiroga
No abstract text is available yet for this article.
December 15, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29099518/diffuse-skin-rash-altered-mental-status-%C3%A2-dx
#18
Caitlyn T Reed, Allison R Cruse, Jeremy D Jackson
A 74-YEAR-OLD CAUCASIAN MAN presented to the hospital with intractable back and chest pain, a diffuse skin rash, and altered mental status. He said that 2 days ago, he'd gone to a different local hospital for treatment of back pain and a headache that had begun 3 days earlier. He was treated with intravenous hydromorphone and sent home with a prescription for meperidine. He said that several hours after being treated with the hydromorphone, the rash developed on his head and then spread to his trunk and upper extremities...
November 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/29048952/increasing-availability-of-illicit-and-prescription-opioids-among-people-who-inject-drugs-in-a-canadian-setting-2010-2014
#19
Joel Ho, Kora DeBeck, M-J Milloy, Huiru Dong, Evan Wood, Thomas Kerr, Kanna Hayashi
BACKGROUND: Nonmedical use of prescription opioid and illicit opioid has been increasing at an alarming rate in North America over the past decade. OBJECTIVE: We sought to examine the temporal trends and correlates of the availability of illicit and prescription opioids among people who inject drugs (PWID) in Vancouver, Canada. METHODS: Data were derived from three prospective cohort studies of PWID in Vancouver between 2010 and 2014. In semiannual interviews, participants reported the availability of five sets of illicit and prescription opioids: (1) heroin; (2) Percocet (oxycodone/acetaminophen), Vicodin (hydrocodone/acetaminophen), or Demerol (meperidine); (3) Dilaudid (hydromorphone); (4) Morphine; (5) oxycontin/OxyNEO (controlled-release oxycodone)...
2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29046773/dexamethasone-alone-versus-in-combination-with-intra-operative-super-hydration-for-postoperative-nausea-and-vomiting-prophylaxis-in-female-patients-undergoing-laparoscopic-cholecystectomy-a-randomized-clinical-trial
#20
Eman A Ismail, Mohamed H Bakri, Sayed Kaoud Abd-Elshafy
BACKGROUND: Dexamethasone has a prophylactic effect on postoperative nausea and vomiting (PONV) and perioperative hydration is believed to play a role in PONV prophylaxis. This study was performed to examine the combined effects of pre-induction dexamethasone plus super-hydration on PONV and pain following laparoscopic cholecystectomy (LC). METHODS: A total of 100 female patients undergoing LC were enrolled and randomized equally into two groups. Group DF received 5 mg dexamethasone (pre-induction) plus 30 ml/kg Ringer's lactate (intraoperative) and group D received 5 mg dexamethasone (pre-induction) alone...
October 2017: Korean Journal of Anesthesiology
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