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https://www.readbyqxmd.com/read/29779388/-the-role-of-ultrasonography-in-the-investigation-of-male-infertility
#1
Zsuzsanna Fejes, Norbert Pásztor, Lilla Karczagi, Ádám Brzózka, István Király, Zita Morvay, András Palkó
Unintended childlessness affects approximately 9-15% of couples in the reproductive age. It is known that a remarkable proportion of infertility is caused by the disorders of the male reproductive functions. Diagnostic imaging methods and especially ultrasonography play a crucial role in the infertility work-up, the ultrasound examination has become the method of choice for imaging in diseases affecting the testis. With the development of high resolution transducers and technology using colour Doppler, pulsed Doppler, share wave elastography and strain elastography, it is now possible to make accurate diagnoses...
May 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29766732/-remission-of-the-disease-associated-related-with-immunoglobulin-igg4-accompanied-by-multiple-lymphadenopathy-after-treatment-with-rituximab-and-dexamethasone-a-case-report
#2
Zdeněk Adam, Zita Chovancová, Markéta Nová, Pavel Fabian, Zdeněk Řehák, Renata Koukalová, Marek Slávik, Luděk Pour, Marta Krejčí, Aleš Čermák, Zdeněk Král, Jiří Mayer
A disease associated with immunoglobulin IgG4 is a rare unit with very variable symptoms. We describe the course and treatment of the disease in a patient who presented with multiple lymphadenopathy and infiltrates in the area of the retroperitoneum and pelvis and signs of chronic sclerosing pancreatitis. The disease was clinically manifested by a significant loss of weight, but also by a loss of perception of taste and smell. The diagnosis was made based on a high amount of IgG4 expressing plasma cells in the sampled tissue and an increased concentration of immunoglobulins of type IgG and mainly subclass IG4...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29766018/usefulness-of-simultaneous-screening-for-hiv-and-hepatitis-c-specific-antibodies-and-hepatitis-b-surface-antigen-by-capillary-based-multiplex-immunochromatographic-rapid-test-to-strengthen-prevention-strategies-and-linkage-to-care-in-childbearing-aged-women
#3
Ralph-Sydney Mboumba Bouassa, Zita Aleyo Nodjikouambaye, Damtheou Sadjoli, Ali Mahamat Moussa, Chatte Adawaye, Donato Koyalta, Laurent Bélec
Childbearing-aged women (n = 266) attending a gynecological clinic in Chad were subjected to multiplex immunochromatographic rapid test for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV). Ten (3.7%) and 8 (3.0%) were seropositive for HIV and HCV, respectively, and 20 (7.5%) for HBV surface antigen, allowing diagnosis of chronic viral infections in 1 of 7 (14.3%) women.
May 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29694713/older-and-wiser-changes-in-unprofessional-content-on-urologists-social-media-from-residency-to-practice
#4
Kevin Koo, Max S Bowman, Zita Ficko, E Ann Gormley
OBJECTIVE: To characterize changes in the frequency and nature of unprofessional content on urologists' Facebook accounts during the transition from residency to practice. METHODS: Facebook was queried with the names of all 2015 U.S. urology graduates one year after completion of residency. We identified unprofessional and potentially-objectionable content on the public Facebook accounts using a rubric based on professionalism guidelines by the American Urological Association, American Medical Association, and Accreditation Council for Graduate Medical Education...
April 25, 2018: BJU International
https://www.readbyqxmd.com/read/29689814/revision-of-the-species-related-to-lalagetes-subfasciatus-boheman-and-transfer-of-remaining-lalagetes-species-to-other-genera-of-embrithini-coleoptera-curculionidae-entiminae
#5
Roman Borovec, JiŘÍ Skuhrovec
The genus Lalagetes Schoenherr, 1842 is redefined, compared with related genera and all known species placed among three genera. Four new species from South Africa are described: L. andersoni sp. nov. (Mpumalanga), L. howdenorum sp. nov. (Limpopo), L. sarkae sp. nov. (KwaZulu-Natal) and L. zitae sp. nov. (KwaZulu-Natal). Lectotypes of Lalagetes seminulum Fåhraeus, 1871 and L. subfasciatus Boheman, 1842 are designated here, and both species redescribed. All of the following species are keyed and illustrated...
January 17, 2018: Zootaxa
https://www.readbyqxmd.com/read/29684296/alcohol-and-drug-intoxications-in-adolescents-admitted-to-paediatric-wards-in-the-czech-republic-5-year-retrospective-study-2006-2010
#6
Pavel Kabíček, Jiří Kobr, Lumír Šašek, Zita Obdržálková, Ludmila Svitálková, Věra Hůrková, Jiří Zeman
OBJECTIVES: The aim of the study was to establish frequency, severity and circumstances of alcohol and drug intoxications in adolescents admitted to inpatient wards in the Czech Republic. METHODS: Chief physician of each participating ward (or their designated deputy) searched the patient records for required information. The data was then statistically processed. RESULTS: Thirty inpatient paediatric wards participated in the study (27 district wards and 3 university hospital wards), amounting to more than a third of all paediatric wards in the country...
March 2018: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29675791/chemotherapy-treatment-is-associated-with-altered-pd-l1-expression-in-lung-cancer-patients
#7
Lívia Rojkó, Lilla Reiniger, Vanda Téglási, Katalin Fábián, Orsolya Pipek, Attila Vágvölgyi, László Agócs, János Fillinger, Zita Kajdácsi, József Tímár, Balázs Döme, Zoltán Szállási, Judit Moldvay
OBJECTIVES: While the predictive value of programmed cell death ligand-1 (PD-L1) protein expression for immune checkpoint inhibitor therapy of lung cancer has been extensively studied, the impact of standard platinum-based chemotherapy on PD-L1 or programmed cell death-1 (PD-1) expression is unknown. The aim of this study was to determine the changes in PD-L1 expression of tumor cells (TC) and immune cells (IC), in PD-1 expression of IC, and in the amount of stromal mononuclear cell infiltration after platinum-based chemotherapy in patients with lung cancer...
April 19, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29629728/the-impact-of-drug-metabolism-gene-polymorphisms-on-therapeutic-response-and-survival-in-diffuse-large-b-cell-lymphoma-patients
#8
Ildikó Pál, Árpád Illés, Lajos Gergely, Tibor Pál, Zita Radnay, Zoltán Szekanecz, Erika Zilahi, László Váróczy
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) accounts for 30% of all non-Hodgkin lymphomas (NHL) and 80% of agressive lymphomas. Besides the traditional International Prognostic Index (IPI), some other factors may also influence the prognosis of DLBCL patients. OBJECTIVES: To study how the genetic polymorphisms in the metabolic pathway influence the event-free and overall survivals and therapeutic responses in DLBCL. METHODS: The study was comprised of 51 patients (32 men, 19 women)...
April 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29570976/spatial-systems-lipidomics-reveals-nonalcoholic-fatty-liver-disease-heterogeneity
#9
Klára Ščupáková, Zita Soons, Gökhan Ertaylan, Keely A Pierzchalski, Gert B Eijkel, Shane R Ellis, Jan W Greve, Ann Driessen, Joanne Verheij, Theo M De Kok, Steven W M Olde Damink, Sander S Rensen, Ron M A Heeren
Hepatocellular lipid accumulation characterizes nonalcoholic fatty liver disease (NAFLD). However, the types of lipids associated with disease progression are debated, as is the impact of their localization. Traditional lipidomics analysis using liver homogenates or plasma dilutes and averages lipid concentrations, and does not provide spatial information about lipid distribution. We aimed to characterize the distribution of specific lipid species related to NAFLD severity by performing label-free molecular analysis by mass spectrometry imaging (MSI)...
April 3, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29550332/reduction-of-nitrosative-stress-by-methane-neuroprotection-through-xanthine-oxidoreductase-inhibition-in-a-rat-model-of-mesenteric-ischemia-reperfusion
#10
Marietta Zita Poles, Nikolett Bódi, Mária Bagyánszki, Éva Fekete, András Tamás Mészáros, Gabriella Varga, Szilárd Szűcs, Anna Nászai, Liliána Kiss, Andrey V Kozlov, Mihály Boros, József Kaszaki
Our aim was to characterize the main components of the nitrosative response with quantitative changes of the nitrergic myenteric neurons in adjacent intestinal segments after transient superior mesenteric artery occlusion. We also tested the hypothesis that exogenous methane may modulate the evolution of nitroxidation by influencing xanthine oxidoreductase (XOR) activity. The microcirculatory consequences of a 50 min ischemia or ischemia-reperfusion were investigated in anesthetized rats (n = 124) inhaling normoxic air with or without 2...
May 20, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29531092/metastudies-for-robust-tests-of-theory
#11
Beth Baribault, Chris Donkin, Daniel R Little, Jennifer S Trueblood, Zita Oravecz, Don van Ravenzwaaij, Corey N White, Paul De Boeck, Joachim Vandekerckhove
We describe and demonstrate an empirical strategy useful for discovering and replicating empirical effects in psychological science. The method involves the design of a metastudy, in which many independent experimental variables-that may be moderators of an empirical effect-are indiscriminately randomized. Radical randomization yields rich datasets that can be used to test the robustness of an empirical claim to some of the vagaries and idiosyncrasies of experimental protocols and enhances the generalizability of these claims...
March 13, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29524904/vulnerability-and-risk-of-deltaic-social-ecological-systems-exposed-to-multiple-hazards
#12
Michael Hagenlocher, Fabrice G Renaud, Susanne Haas, Zita Sebesvari
Coastal river deltas are hotspots of global change impacts. Sustainable delta futures are increasingly threatened due to rising hazard exposure combined with high vulnerabilities of deltaic social-ecological systems. While the need for integrated multi-hazard approaches has been clearly articulated, studies on vulnerability and risk in deltas either focus on local case studies or single hazards and do not apply a social-ecological systems perspective. As a result, vulnerabilities and risks in areas with strong social and ecological coupling, such as coastal deltas, are not fully understood and the identification of risk reduction and adaptation strategies are often based on incomplete assumptions...
August 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29524551/the-influence-of-familiarity-and-temperature-on-the-huddling-behavior-of-two-mouse-species-with-contrasting-social-systems
#13
Zita Groó, Péter Szenczi, Oxána Bánszegi, Zsófia Nagy, Vilmos Altbäcker
Huddling with other individuals is an effective way to reduce heat loss. This cooperative behavior requires that the individuals tolerate each other's presence at least for a certain time or under certain circumstances. In our study, we investigated the effects of ambient temperature and familiarity on the huddling behavior of two closely related mouse species, the mound-building mouse (Mus spicilegus) and the house mouse (Mus musculus musculus). While their geographic distribution overlaps, their social systems differ in many aspects...
June 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29523335/development-of-a-non-human-primate-bcg-infection-model-for-the-evaluation-of-candidate-tuberculosis-vaccines
#14
Stephanie A Harris, Andrew White, Lisa Stockdale, Rachel Tanner, Laura Sibley, Charlotte Sarfas, Joel Meyer, Jonathan Peter, Matthew K O'Shea, Zita-Rose Manjaly Thomas, Ali Hamidi, Iman Satti, Mike J Dennis, Helen McShane, Sally Sharpe
The lack of validated immunological correlates of protection makes tuberculosis vaccine development difficult and expensive. Using intradermal bacille Calmette-Guréin (BCG) as a surrogate for aerosol Mycobacterium tuberculosis (M.tb) in a controlled human infection model could facilitate vaccine development, but such a model requires preclinical validation. Non-human primates (NHPs) may provide the best model in which to do this. Cynomolgus and rhesus macaques were infected with BCG by intradermal injection...
January 2018: Tuberculosis
https://www.readbyqxmd.com/read/29511361/late-presentation-of-infected-silicone-granulomas-in-the-lower-limb
#15
Zita M Jessop, Matthew Welck, Emily Zinser, Nicholas Garlick, Susan Hopkins
Introduction: Dermal fillers are used for multiple cosmetic indications including gluteal and thigh augmentation. Complications, although infrequent, are increasing due to the dramatic growth of dermal filler use. Our aim was to describe how the complication of infected silicone granulomas can present following lower limb augmentation. Methods: Two cases presented with pain, oedema, and erythema at the site of previous silicone filler injection, following a considerable delay after the last injection (range 4-7 years)...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29487905/functional-odor-classification-through-a-medicinal-chemistry-approach
#16
Erwan Poivet, Narmin Tahirova, Zita Peterlin, Lu Xu, Dong-Jing Zou, Terry Acree, Stuart Firestein
Crucial for any hypothesis about odor coding is the classification and prediction of sensory qualities in chemical compounds. The relationship between perceptual quality and molecular structure has occupied olfactory scientists throughout the 20th century, but details of the mechanism remain elusive. Odor molecules are typically organic compounds of low molecular weight that may be aliphatic or aromatic, may be saturated or unsaturated, and may have diverse functional polar groups. However, many molecules conforming to these characteristics are odorless...
February 2018: Science Advances
https://www.readbyqxmd.com/read/29478779/loss-of-function-of-the-nuclear-receptor-nr2f2-encoding-coup-tf2-causes-testis-development-and-cardiac-defects-in-46-xx-children
#17
Anu Bashamboo, Caroline Eozenou, Anne Jorgensen, Joelle Bignon-Topalovic, Jean-Pierre Siffroi, Capucine Hyon, Attila Tar, Péter Nagy, Janos Sólyom, Zita Halász, Annnabel Paye-Jaouen, Sophie Lambert, David Rodriguez-Buritica, Rita Bertalan, Laetitia Martinerie, Ewa Rajpert-De Meyts, John C Achermann, Ken McElreavey
Emerging evidence from murine studies suggests that mammalian sex determination is the outcome of an imbalance between mutually antagonistic male and female regulatory networks that canalize development down one pathway while actively repressing the other. However, in contrast to testis formation, the gene regulatory pathways governing mammalian ovary development have remained elusive. We performed exome or Sanger sequencing on 79 46,XX SRY-negative individuals with either unexplained virilization or with testicular/ovotesticular disorders/differences of sex development (TDSD/OTDSD)...
March 1, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29472575/glial-cell-type-specific-changes-in-spinal-dipeptidyl-peptidase-4-expression-and-effects-of-its-inhibitors-in-inflammatory-and-neuropatic-pain
#18
Kornél Király, Márk Kozsurek, Erika Lukácsi, Benjamin Barta, Alán Alpár, Tamás Balázsa, Csaba Fekete, Judit Szabon, Zsuzsanna Helyes, Kata Bölcskei, Valéria Tékus, Zsuzsanna E Tóth, Károly Pap, Gábor Gerber, Zita Puskár
Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various pain states, and remain difficult to treat. We have shown previously that spinal application of dipeptidyl peptidase 4 (DPP4) inhibitors induces strong antihyperalgesic effect during inflammatory pain. In this study we observed low level of DPP4 mRNA in the rat spinal dorsal horn in physiological conditions, which did not change significantly either in carrageenan-induced inflammatory or partial nerve ligation-generated neuropathic states...
February 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29461517/arthropods-dataset-from-different-genetically-modified-maize-events-and-associated-controls
#19
Zoltán Pálinkás, Mihály Zalai, Ágnes Szénási, Zita Dorner, József Kiss, Samuel North, Guy Woodward, Adalbert Balog
Arthropods from four genetically modified (GM) maize hybrids (coleopteran resistant, coleopteran and lepidopteran resistant, lepidopteran resistant+herbicide tolerant and coleopteran resistant and herbicide tolerant) and non-GM varieties were sampled during a two-year field assessment. A total number of 363 555 arthropod individuals were collected. This represents the most comprehensive arthropod dataset from GM maize, and together with weed data, is reasonable to determine functional groups of arthropods and interactions between species...
February 20, 2018: Scientific Data
https://www.readbyqxmd.com/read/29453021/towards-sustainable-feedstocks-a-guide-to-electron-donors-for-microbial-carbon-fixation
#20
REVIEW
Nico Joannes Claassens, Irene Sánchez-Andrea, Diana Zita Sousa, Arren Bar-Even
The replacement of fossil and agricultural feedstocks with sustainable alternatives for the production of chemicals and fuels is a societal and environmental necessity. This challenge can be tackled by using inorganic or one-carbon compounds as electron donors for microbial CO2 fixation and bioproduction. Yet, considering the wide array of microbial electron donors, which are the best suited for bioindustry? Here, we propose criteria to evaluate these compounds, considering factors such as production methods, physicochemical properties, and microbial utilization...
April 2018: Current Opinion in Biotechnology
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