keyword
MENU ▼
Read by QxMD icon Read
search

thyroid disease and pregnancy

keyword
https://www.readbyqxmd.com/read/29771756/thyrotropin-receptor-antibodies-an-overview
#1
Anupam Kotwal, Marius Stan
PURPOSE: Thyroid autoimmunity affects approximately 5% of the population, and its investigation relies heavily on the use of autoantibodies. Thyroid stimulating hormone receptor (TSHR) autoantibodies (TRAb) play a central role in the evaluation of Graves disease (GD), Graves ophthalmopathy (GO) and pretibial myxedema (PTM). However, there is still controversy regarding overall TRAb assay diagnostic accuracy and their prognostic utility. METHODS: We reviewed and analyzed the literature reporting TRAb assays and their clinical utility...
May 2, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29764026/-advances-in-postoperative-thyroid-stimulating-hormone-suppression-therapy-in-females-with-thyroid-cancer
#2
F Song, H L Yi
Differentiated thyroid cancer is the most common malignant carcinoma in female population.Postoperative long-term thyroid-stimulating hormone(TSH) suppression therapy can reduce the risk of recurrence for differentiated thyroid cancer and control the progress of the disease, but it also induces simultaneously subclinical hypothyroidism and imposes negative effect on female. In addition to cardiovascular disease, TSH suppression therapy can lead to the alteration of sex hormone metabolism, menstrual disorder, poor influence on pregnancy and osteoporosis...
May 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29757392/thyroid-function-in-early-pregnancy-child-iq-and-autistic-traits-a-meta-analysis-of-individual-participant-data
#3
Deborah Levie, Tim I M Korevaar, Sarah C Bath, Albert Dalmau-Bueno, Mario Murcia, Mercedes Espada, Mariana Dineva, Jesús M Ibarluzea, Jordi Sunyer, Henning Tiemeier, Marisa Rebagliato, Margaret P Rayman, Robin P Peeters, Mònica Guxens
Context: Low maternal free thyroxine (FT4) has been associated with poor child neurodevelopment in some single-centre studies. Evidence remains scarce for potential adverse effects of high FT4 and whether associations differ in countries with a different iodine status. Objective: To assess the association of maternal thyroid function in early pregnancy with child neurodevelopment in countries with a different iodine status. Design, Setting and Participants: Meta-analysis of individual-participant data compromising 9,036 mother-child pairs from three prospective population-based birth cohorts: INMA (Spain), Generation R (The Netherlands) and ALSPAC (United Kingdom)...
May 10, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29727207/the-impact-of-autoimmunity-related-early-ovarian-aging-on-icsi-cycle-outcome
#4
Gulay Beydilli Nacak, Enis Ozkaya, Cigdem Yayla Abide, Bulent Emre Bilgic, Belgin Devranoglu, Reyyan Gokcen Iscan
The aim of this study was to investigate the impact of anti-thyroid peroxidase antibodies (Anti-TPO) on the in vitro fertilization and embryo transfer (IVF-ET) outcome in women with poor ovarian reserve but normal thyrotropin levels. A total of 300 patients with poor ovarian reserve undergoing ICSI cycle from April 2015 to December 2017 were analyzed retrospectively. Subjects were divided into two groups: Group 1: Women with early ovarian aging, Group 2: Women with age related poor ovarian reserve. All subjects underwent anti-thyroid peroxidase antibody (anti-TPO) analysis...
May 4, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29725285/ovarian-endometriosis-risk-factor-analysis-and-prediction-of-malignant-transformation
#5
YanNa Zhou, Ke-Qin Hua
Introduction: For the prediction of endometriosis associated ovarian carcinoma (EAOC), the risk factors for malignant ovarian endometriosis (MOE) were explored. Material and methods: A group of 104 EAOC patients was compared with a group of 104 ovarian endometrial cyst patients. Using single and multivariate risk analysis of EAOC by calculating the area under the curve (AUC) of receiver-operator characteristics (ROC) curves, risks of MOE transformation were calculated for various burdens of risk factors...
March 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29707880/risk-factors-for-adverse-maternal-and-perinatal-outcomes-in-women-with-preeclampsia-analysis-of-1396-cases
#6
Xun Li, Weishe Zhang, Jianhua Lin, Huai Liu, Zujing Yang, Yincheng Teng, Si Duan, Xinxiu Lin, Yingming Xie, Yuanqiu Li, Liangqun Xie, Qiaozhen Peng, Lu Xia
Preeclampsia is a major cause of adverse maternal and perinatal outcomes, but how to identify women and fetuses at increased risk for later adverse events is a challenge. This study aimed to investigate the risk factors for adverse maternal and perinatal outcomes in women with preeclampsia. Data from 1396 women with preeclampsia were retrospectively collected and analyzed. Eighteen candidate risk factors and 12 adverse outcomes were investigated. The following factors were found to be significantly associated with at least one adverse outcome: maternal age 35 years or older, multiple birth, the usage of assisted reproductive technology, living in a rural area, history of pregnancy-induced hypertension, male fetus, multigravida, or having polycystic ovary syndrome, hemolysis, elevated liver enzymes, and low platelet count syndrome, intrahepatic cholestasis of pregnancy, cardiovascular disease, gestational diabetes mellitus, systemic lupus erythematosus, thyroid disease, or liver disease...
April 30, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29706030/preconception-management-of-thyroid-dysfunction
#7
Onyebuchi E Okosieme, Ishrat Khan, Peter N Taylor
Uncorrected thyroid dysfunction in pregnancy has well recognised deleterious effects on fetal and maternal health. The early gestation period is one of critical fetal vulnerability during which maternal thyroid dysfunction may have lasting repercussions. Accordingly, a pragmatic preconception strategy is key for ensuring optimal thyroid disease outcomes in pregnancy. Preconception planning in women with hypothyroidism should pre-empt and mirror the adaptive changes of the thyroid gland by careful levothyroxine dose adjustments to ensure adequate fetal thyroid hormone delivery in pregnancy...
April 29, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29700098/high-prevalence-of-iodine-deficiency-in-pregnant-women-living-in-adequate-iodine-area
#8
Veronica Carneiro Borges Mioto, Ana Carolina Castro Nassif Gomes Monteiro, Rosalinda Y A Camargo, Andreia Rodrigues Borel, Regina Maria Catarino, Sergio Kobayashi, Maria Cristina Chammas, Suemi Marui
INTRODUCTION: Iodine deficiency during pregnancy is associated with obstetrical and neonatal adverse outcomes. Serum thyroglobulin (sTg) and thyroid volume (TV) are optional tools to urinary iodine concentration (UIC) for defining iodine status. This cross sectional study aims to evaluate the iodine status of pregnant women living in iodine-adequate area by spot UIC and correlation with sTg, TV and thyroid function. METHODS: 273 pregnant women were evaluated at three trimesters...
April 26, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29699957/iodine-deficiency-in-pregnant-women-at-first-trimester-in-ankara
#9
Kazibe Koyuncu, Batuhan Turgay, Feride Söylemez
OBJECTIVE: Iodine deficiency in pregnant woman in Ankara was shown in previous studies. We aimed to conduct a study in a tertiary center to investigate for the need for iodine replacement in our population. MATERIAL AND METHODS: This was a single tertiary center, non-interventional, retrospective, cross-sectional study. Data were retrieved retrospectively from 440 women who had been in first trimester in gestational age. Maternal iodine status, TSH levels, T4 levels were examined...
April 27, 2018: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29644934/management-of-subclinical-hypothyroidism-in-pregnancy-a-comment-from-the-italian-society-of-endocrinology-sie-and-the-italian-thyroid-association-ait-to-the-2017-ata-guidelines-the-italian-way
#10
Mario Rotondi, Luca Chiovato, Furio Pacini, Luigi Bartalena, Paolo Vitti
The 2017 ATA Guidelines for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum were published six years after the previous ones. They provide comprehensive clinical recommendations for the whole spectrum of thyroid diseases as well as for optimal iodine intake during pregnancy, post-partum and lactation. The present position statement mainly regards the recommended flow-chart for therapeutic decision making in pregnant women being diagnosed with subclinical hypothyroidism. The major biochemical and clinical situations and the corresponding therapeutic indications will be commented...
April 12, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29607233/preterm-parturient-with-polyhydramnios-and-pancreatitis-primary-presentation-of-hyperparathyroidism
#11
Esther S Han, Katherine Fritton, Phoebe Bacon, Martin K Slodzinski, Cynthia Argani
Objective: To report a case of severe hypercalcemia secondary to primary hyperparathyroidism in a late-preterm pregnant patient and review medical and surgical treatments as well as obstetric and neonatal outcomes. Background: Diagnosis of parathyroid disease during pregnancy can be difficult due to nonspecific presentation. Management decisions are complex and require multidisciplinary collaboration. Case: A 29-year-old G2P1001 woman at 35 weeks and 3 days' gestation presented with preterm contractions, polyhydramnios, pancreatitis, and severe hypercalcemia...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29606182/review-dairy-foods-red-meat-and-processed-meat-in-the-diet-implications-for-health-at-key-life-stages
#12
D I Givens
Social and health care provision have led to substantial increases in life expectancy. In the UK this has become higher than 80 years with an even greater proportional increase in those aged 85 years and over. The different life stages give rise to important nutritional challenges and recent reductions in milk consumption have led to sub-optimal intakes of calcium by teenage females in particular when bone growth is at its maximum and of iodine during pregnancy needed to ensure that supply/production of thyroid hormones to the foetus is adequate...
April 2, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29605392/prediction-of-neonatal-hyperthyroidism
#13
Maïa Banigé, Michel Polak, Dominique Luton
OBJECTIVES: To assess whether it is possible to identify the neonatal predictors of neonatal hyperthyroidism at the presymptomatic stage of the disease. STUDY DESIGN: This retrospective multicenter study in 10 maternity units was based on the medical records of all patients monitored for a pregnancy between January 1, 2007, and January 1, 2014. Among 280 000 births, 2288 medical records of women with thyroid dysfunction were selected and screened. Of these, 415 women had Graves disease and were positive for thyrotropin receptor antibody during pregnancy, and were included...
March 28, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29589552/evaluation-and-management-of-the-child-with-thyrotoxicosis
#14
Alexander K C Leung, Alexander A C Leung
BACKGROUND: Uncontrolled thyrotoxicosis, especially in early infancy, may cause irreversible damage to the central nervous system as well as profound effects on the function of many organs. Thyrotoxicosis has multiple etiologies and treatment depends on the underlying etiology. An accurate diagnosis is essential so that appropriate treatment can be initiated without undue delay. OBJECTIVE: To review in depth the evaluation, diagnosis, and treatment of children with thyrotoxicosis...
March 26, 2018: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
https://www.readbyqxmd.com/read/29572405/thyroid-disrupting-chemicals-and-brain-development-an-update
#15
Bilal B Mughal, Jean-Baptiste Fini, Barbara Demeneix
This review covers recent findings on the main categories of thyroid hormone disrupting chemicals and their effects on brain development. We draw mostly on epidemiological and experimental data published in the last decade. For each chemical class considered, we deal with not only the thyroid hormone disrupting effects but also briefly mention the main mechanisms by which the same chemicals could modify estrogen and/or androgen signalling, thereby exacerbating adverse effects on endocrine-dependent developmental programs...
March 23, 2018: Endocrine Connections
https://www.readbyqxmd.com/read/29557233/aetiology-of-recurrent-miscarriage-and-the-role-of-adjuvant-treatment-in-its-management-a-retrospective-cohort-review
#16
Samuel James Alexander Dobson, Kanna Mannadiar Jayaprakasan
We conducted a retrospective review into the role of commonly prescribed conventional adjuvant treatments in improving live birth rates after recurrent miscarriage (RM). Data from 301 couples attending the RM clinic in two Tertiary teaching hospitals were analysed with their live birth rate following a further pregnancy and a prevalence of conditions investigated in RM being the main outcomes measured. We found that 26% of women had explained RM and 74% had unexplained RM. Adjuvant versus conservative management did not improve the live birth rates in those with unexplained RM (68...
March 20, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29544795/associations-of-maternal-iodine-status-and-thyroid-function-with-adverse-pregnancy-outcomes-in-henan-province-of-china
#17
Jin Yang, Yang Liu, Hongjie Liu, Heming Zheng, Xiaofeng Li, Lin Zhu, Zhe Wang
OBJECTIVE: The study aimed to explore the effects of maternal iodine status and thyroid diseases on adverse pregnancy outcomes. METHODS: A prospective study was conducted on 2347 pregnant women, who provided 2347 urinary samples tested for iodine, 1082 serum samples tested for thyroid function, and 2347 questionnaires about demographic information. Their pregnancy outcomes were recorded and compared between different urinary iodine concentration (UIC) and thyroid function groups...
May 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29535929/a-systematic-review-on-normative-values-of-trimester-specific-thyroid-function-tests-in-indian-women
#18
Subramanian Kannan, Shriraam Mahadevan, Alben Sigamani
Background: Small cross-sectional studies are published on the trimester-specific normal ranges of thyrotropin and thyroxine levels in Indian women from various parts of the country. Objective: We sought to review the published literature on thyroid function tests in normal pregnant Indian women to see if the pooled data from various studies can define normative data and hypothyroidism in pregnancy. Methods: We retrieved 56 studies from online databases with detailed search using multiple search terms...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29527855/thyroid-disease-in-pregnancy-a-clinical-survey-among-endocrinologists-gynecologists-and-obstetricians-in-israel
#19
Ronit Koren, Yifat Wiener, Karen Or, Carlos A Benbassat, Shlomit Koren
OBJECTIVES: To study the current practices in the management of subclinical hypothyroidism (SCH) and thyroid nodules during pregnancy of obstetricians/gynecologists (OB/GYNs) and endocrinologists in Israel. METHODS: An electronic questionnaire was sent by email to all members of the Israeli Endocrine Society and the Israel Society of Obstetrics and Gynecology. Questionnaires included demographic data and clinical scenarios with questions regarding the screening and management of pregnant women with SCH, hypothyroxinemia, and a palpable thyroid nodule...
March 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29526990/false-positive-tsh-receptor-antibody-a-pitfall-of-third-generation-tsh-receptor-antibody-measurements-in-neonates
#20
Michiko Wada, Makoto Kita, Kaoru Kawasaki, Toru Kusakabe, Tetsuya Tagami, Noriko Satoh-Asahara, Akira Shimatsu, Koshi Hashimoto
Maternal Graves' disease (GD) during pregnancy may influence thyroid function in fetuses. Neonates born to mothers with high serum TSH receptor antibody (TRAb) levels have been reported to develop 'neonatal GD'. Therefore, evaluations of serum thyroid hormone and TRAb levels in neonates upon birth are crucial for a prompt diagnosis. At delivery, we measured TRAb with third-generation TRAb test using an M22 human monoclonal antibody in neonates by collecting umbilical cord blood in a blood collection tube with lithium-heparin, which provides a whole blood/plasma sample...
March 10, 2018: Endocrine Journal
keyword
keyword
93615
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"