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Functional dyspepsia

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https://www.readbyqxmd.com/read/29161458/proton-pump-inhibitors-for-functional-dyspepsia
#1
REVIEW
Maria Ines Pinto-Sanchez, Yuhong Yuan, Ahmed Hassan, Premysl Bercik, Paul Moayyedi
BACKGROUND: Functional dyspepsia (FD or non-ulcer dyspepsia) is defined as continuous or frequently recurring epigastric pain or discomfort for which no organic cause can be found. Acid suppressive therapy, including proton pump inhibitors (PPIs), has been proposed as a therapeutic option in FD, but its efficacy remains controversial. While PPIs are generally considered safe and well tolerated, they have been associated with adverse events, especially in the long term. For this reason, decisions on whether to initiate or continue PPI therapy should be made based on an appropriate clinical indication...
November 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29144152/new-psychometric-data-from-the-spanish-versions-of-the-glasgow-dyspepsia-severity-score-and-the-dyspepsia-related-health-scale-measures
#2
Miren Orive, Ane Antón-Ladislao, Nerea González, Begoña Matellanes, Jesús Ángel Padierna, José Luis Cabriada, Aitor Orive, Víctor Manuel Orive, José María Quintana
BACKGROUND AND OBJECTIVE: There are no structural abnormalities in functional dyspepsia, therefore it is essential to have a viable questionnaire to measure treatment outcome according to patient perception. The aim of the study was to extensively document psychometric characteristics of the Glasgow Dyspepsia Severity Score and the Dyspepsia-Related Health Scale that are currently available in Spanish. METHODS: Patients with functional dyspepsia (n = 158) were recruited from a randomized trial that assessed standard vs...
November 16, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29134293/medicinal-foods-for-functional-gi-disorders
#3
REVIEW
Brent W Acker, Brooks D Cash
PURPOSE OF REVIEW: Over the past 10 years, there has been a dramatic increase in basic and clinical research involving functional gastrointestinal disorders (FGIDs). New diagnostic and biomarker procedures are helping to identify physiologic disruptions associated with FGIDs on cellular and molecular levels. Simultaneously, clinicians are using new approaches to help manage patients with FGIDs. Among these, an important component of care has been the use of medical foods. These include probiotics, prebiotics, synbiotics, peppermint oil, caraway oil, curcumin, bovine immunoglobulin and many others...
November 13, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29132415/acupuncture-for-postprandial-distress-syndrome-apds-study-protocol-for-a-randomized-controlled-trial
#4
Jing-Wen Yang, Li-Wen Zhang, Guang-Xia Shi, Yi Du, Jun Wang, Jing-Jie Zhao, Yan Cao, Jian-Feng Tu, Shuai Zhang, Cheng Tan, San-San Chen, Cun-Zhi Liu
BACKGROUND: Postprandial distress syndrome (PDS) is referred to as meal-related functional dyspepsia (FD) and causes a reduced quality of life (QoL) for patients. Several randomized controlled trials (RCTs) have suggested that acupuncture is an effective treatment for FD, but few studies were particularly for PDS. This pilot study was designed to determine the feasibility and efficacy of acupuncture in patients with PDS characterized by postprandial fullness and early satiation according to the Rome III criteria...
November 13, 2017: Trials
https://www.readbyqxmd.com/read/29121988/efficacy-of-banha-sasim-tang-on-functional-dyspepsia-classified-as-excess-pattern-study-protocol-for-a-randomized-controlled-trial
#5
Yun Hee Kim, Jun Young Kim, So Young Jung, O-Jin Kwon, Jun-Hwan Lee, Chang-Gue Son
BACKGROUND: Functional dyspepsia (FD) refers to the presence of one or more gastrointestinal symptoms including postprandial fullness, epigastric pain, burning, and early satiety without an organic explanation for chronic symptoms. FD causes considerable discomfort in patients and affects their everyday activity and productivity. Because most conventional treatments have limited efficacy, numerous patients seek alternatives such as herbal medicines. In this proposed study, we will conduct a clinical trial of an herbal drug, Banha-sasim-tang (BST)...
November 9, 2017: Trials
https://www.readbyqxmd.com/read/29111202/intestinal-fructose-malabsorption-is-associated-with-increased-lactulose-fermentation-in-the-intestinal-lumen-of-patients-with-abdominal-pain
#6
Roberto Koity Fujihara Ozaki, Patrícia da Graça Leite Speridião, Ana Cristina Fontenele Soares, Mauro Batista de Morais
OBJECTIVE: To study fructose malabsorption in children and adolescents with abdominal pain associated with functional gastrointestinal disorders. As an additional objective, the association between intestinal fructose malabsorption and food intake, including the estimated fructose consumption, weight, height, and lactulose fermentability were also studied. METHODS: The study included 31 patients with abdominal pain (11 with functional dyspepsia, 10 with irritable bowel syndrome, and 10 with functional abdominal pain)...
October 28, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29099094/functional-dyspepsia
#7
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
November 3, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29099093/functional-dyspepsia
#8
REVIEW
Paul Enck, Fernando Azpiroz, Guy Boeckxstaens, Sigrid Elsenbruch, Christine Feinle-Bisset, Gerald Holtmann, Jeffrey M Lackner, Jukka Ronkainen, Michael Schemann, Andreas Stengel, Jan Tack, Stephan Zipfel, Nicholas J Talley
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders. Functional dyspepsia comprises three subtypes with presumed different pathophysiology and aetiology: postprandial distress syndrome (PDS), epigastric pain syndrome (EPS) and a subtype with overlapping PDS and EPS features. Functional dyspepsia symptoms can be caused by disturbed gastric motility (for example, inadequate fundic accommodation or delayed gastric emptying), gastric sensation (for example, sensations associated with hypersensitivity to gas and bloating) or gastric and duodenal inflammation...
November 3, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29092728/extensive-gastric-mucosal-atrophy-is-a-possible-predictor-of-clinical-effectiveness-of%C3%A2-acotiamide-in-patients-with-functional-dyspepsia%C3%A2
#9
Atsushi Miki, Takatsugu Yamamoto, Kyohei Maruyama, Naohiro Nakamura, Hitoshi Aoyagi, Akari Isono, Koichiro Abe, Hiroto Kita
BACKGROUND: Acotiamide is known as an effective agent for functional dyspepsia. However, clinical factors related to its effectiveness have not been fully elucidated, so it is difficult to predict the drug's effectiveness prior to its administration in patients. AIMS: The present retrospective study was conducted to examine the relationship between clinical factors and the effectiveness of acotiamide for functional dyspepsia. MATERIALS AND METHODS: The study subjects were 149 patients with functional dyspepsia who were prescribed acotiamide...
October 26, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29083538/functional-dyspepsia-and-duodenal-eosinophilia-a-new-disease-model
#10
REVIEW
Kening Fan, Nicholas J Talley
Functional dyspepsia (FD) is a highly prevalent disorder that affects more than 10% of the population. In the past decade, the conceptual underpinning of FD has begun to change, and new data are unraveling the underlying pathophysiological mechanisms of this disorder with a focus on the duodenum. The Rome IV criteria were published in 2016, and notably suggests that gastroesophageal reflux disease and irritable bowel syndrome may all be part of the same disease spectrum as FD. Helicobacter pylori explains a minority of FD cases and in Rome IV is considered a separate entity...
October 30, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29073345/interpreting-the-chinese-version-of-quality-of-life-questionnaire-for-functional-digestive-disorders
#11
Zheng-Kun Hou, Hong Mi, Feng-Bin Liu, Zhuo-Qun Chen, Xin-Lin Chen, Yu-Hang Wu, Xiao-Lu Che
BACKGROUND AND AIM: The Chinese version Quality of Life Questionnaire for Functional Digestive Disorders (Chin-FDDQL) is a useful health assessment instrument for functional dyspepsia. This study aims to identify its score interpretation for clinical practice. METHODS: Data of Chin-FDDQL from the FD patients (≥18yrs) between Nov. 2009 and Apr. 2013 were enrolled in the 1st and 14th day. After baseline and responsiveness analysis, the single score interpretation and percentile ranks were established...
October 26, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29072022/-progress-on-the-relationship-between-the-regulation-of-gastrointestinal-system-function-by-acupuncture-and-central-nuclei
#12
Fan-You Bu, Feng Wei, Xue-Shuang Dai, Qi-Wen Tan, Bin Cheng
Acupuncture has a good curative effect in the treatment of gastrointestinal system diseases, such as functional dyspepsia, ulcerative colitis, and constipation. The central nuclei which are involved in the mechanism of acupuncture in regulating the gastrointestinal system have become a research hotspot in recent years. In the present paper, the authors summarized the effect of acupuncture and the central nervous system on gastrointestinal function regulation. It was found that the regulation of gastrointestinal function by acupuncture involved many brain regions such as the amygdala, paraventricular nucleus, locus coeruleus, raphe nucleus, and dorsal nucleus of the vagus nerve...
August 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29063898/pattern-of-presentation-of-gastroesophageal-reflux-disease-among-patients-with-dyspepsia-in-kano-nigeria
#13
Abubakar Sadiq Maiyaki, Musa Muhammed Borodo, Adamu Alhaji Samaila, Abdulmumini Yakubu
BACKGROUND: Dyspepsia is a symptom complex rather than a specific disease entity. It can be caused by both organic and functional gastrointestinal (GI) disorders. Gastroesophageal reflux disease (GORD) though a common digestive disorder worldwide is scarcely reported in Nigeria. The aim of this study is to determine the pattern of presentation of GORD among patients with dyspepsia. METHODS: One hundred and seventy dyspeptic patients were recruited consecutively as they were referred to the Gastroenterology Unit of Aminu Kano Teaching Hospital for upper GI endoscopy...
October 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/29043076/the-management-of-functional-dyspepsia-in-clinical-practice-what-lessons-can-be-learnt-from-recent-literature
#14
REVIEW
Maura Corsetti, Mark Fox
Functional dyspepsia is a prevalent functional gastrointestinal disorder that can significantly erode the quality of life of sufferers and places a major cost burden on healthcare services. In this article, we review the recent literature, selecting the information we consider relevant since it has changed our clinical management of patients with functional dyspepsia.
2017: F1000Research
https://www.readbyqxmd.com/read/29035975/breath-hydrogen-testing-in-east-and-southeast-asia
#15
Chu Kion Yao, Natural Hoi Sing Chu, Victoria Ping Yi Tan
Breath hydrogen tests are popular, noninvasive tests for the assessment of carbohydrate fermentation in patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). There is limited information regarding the utility of breath hydrogen and methane tests in IBS and FD patients in East and Southeast Asia. This review aims to summarize current literature about common indications of breath testing in this region, the genesis of functional gastrointestinal symptoms by provocative breath testing and provide suggestions for correct use...
October 13, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29021437/a-systematic-review-of-the-effectiveness-of-antianxiety-and-antidepressive-agents-for-functional-dyspepsia
#16
Mariko Hojo, Akihito Nagahara, Daisuke Asaoka, Yuji Shimada, Sasaki Hitoshi, Kohei Matsumoto, Tsutomu Takeda, Hiroya Ueyama, Kenshi Matsumoto, Sumio Watanabe
Background and Aim Functional dyspepsia (FD) is defined as persistent or recurrent pain or discomfort centered in the upper abdomen without organic disease. Psychosocial factors have been proposed as an important element in the pathophysiology of FD. Therefore, psychotropic agents having antianxiety or antidepressive action are expected to alleviate FD. We previously reported on the treatment of FD using such agents in a systematic review, wherein the effectiveness of the agents on FD was suggested, although there were several limitations...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29017683/the-appropriate-sample-to-define-functional-dyspepsia
#17
Rinaldo Pellicano, Ommara Jamil
No abstract text is available yet for this article.
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28992677/nationwide-multicenter-study-for-overlaps-of-common-functional-gastrointestinal-disorders-in-korean-patients-with-constipation
#18
Kyung Sik Park, Sam Ryong Jee, Bong Eun Lee, Kyoung Sup Hong, Jeong Eun Shin, Soo-Young Na, Joong Goo Kwon, Suck Chei Choi, Yong Sung Kim, Hyun Seok Lee, Tae Hee Lee, Kyeong Ok Kim, Jongkyoung Choi, Hee Seok Moon, Yeon Soo Kim, Moo In Park, Soo Jung Park, Seon-Young Park, Sung Noh Hong
Background/Aims: In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we investigated the patterns of overlaps between constipation and other common FGIDs. Methods: This study was designed as a prospective nationwide multi-center questionnaire study using Rome III questionnaires for functional dyspepsia (FD), irritable bowel syndrome (IBS), and functional constipation (FC), as well as various questionnaires about patients' information, degree of symptoms, and quality of life...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28992674/is-helicobacter-pylori-associated-functional-dyspepsia-correlated-with-dysbiosis
#19
REVIEW
Yeon-Ji Kim, Woo Chul Chung, Byung Wook Kim, Sung Soo Kim, Jin Il Kim, Na Jin Kim, Jinho Yoo, Soo Hwan Kim
Background/Aims: To assess the long-term effect of Helicobacter pylori eradication on symptomatic improvement according to the type of antibiotic and the duration of treatment in H. pylori-associated functional dyspepsia. Methods: We searched Pubmed, Embase, CINAHL, and the Cochrane library databases for randomized controlled trials written in English and undertaken up to August 2016 that met our eligibility criteria. The search methodology used combinations of the following keywords: Helicobacter pylori OR H...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28987135/non-coeliac-gluten-or-wheat-sensitivity-emerging-disease-or-misdiagnosis
#20
REVIEW
Michael DE Potter, Marjorie M Walker, Nicholas J Talley
Non-coeliac gluten or wheat sensitivity (NCG/WS) is a condition characterised by adverse gastrointestinal and/or extra-intestinal symptoms associated with the ingestion of gluten- or wheat-containing foods, in the absence of coeliac disease or wheat allergy. Up to one in 100 people in Australia may have coeliac disease but many more report adverse gastrointestinal and/or extra-intestinal symptoms after eating wheat products. In the absence of validated biomarkers, a diagnosis of NCG/WS can only be made by a double-blind, placebo-controlled, dietary crossover challenge with gluten, which is difficult to apply in clinical practice...
August 4, 2017: Medical Journal of Australia
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