keyword
MENU ▼
Read by QxMD icon Read
search

Data display

keyword
https://www.readbyqxmd.com/read/29166406/revised-geochronology-correlation-and-dinosaur-stratigraphic-ranges-of-the-santonian-maastrichtian-late-cretaceous-formations-of-the-western-interior-of-north-america
#1
Denver Warwick Fowler
Interbasinal stratigraphic correlation provides the foundation for all consequent continental-scale geological and paleontological analyses. Correlation requires synthesis of lithostratigraphic, biostratigraphic and geochronologic data, and must be periodically updated to accord with advances in dating techniques, changing standards for radiometric dates, new stratigraphic concepts, hypotheses, fossil specimens, and field data. Outdated or incorrect correlation exposes geological and paleontological analyses to potential error...
2017: PloS One
https://www.readbyqxmd.com/read/29166384/neanderthal-hunting-strategies-inferred-from-mortality-profiles-within-the-abric-roman%C3%A3-sequence
#2
Juan Marín, Palmira Saladié, Antonio Rodríguez-Hidalgo, Eudald Carbonell
Ungulate mortality profiles are commonly used to study Neanderthal subsistence strategies. To assess the hunting strategies used by Neanderthals, we studied the ages at death of the cervids and equids found in levels E, H, I, Ja, Jb, K, L and M of the Abric Romaní sequence. These levels date between 43.2 ± 1.1 ka BP (14C AMS) and 54.5 ± 1.7 ka BP (U-series). The degree of eruption and development of the teeth and their wear stages were used to determine the ages of these animals at death, and mortality profiles were constructed using these data...
2017: PloS One
https://www.readbyqxmd.com/read/29166348/the-economics-of-prepectoral-breast-reconstruction
#3
Scot Bradley Glasberg
The world of breast reconstruction over the last several years has seen a dramatic shift in focus to discussion and the application of placing tissue expanders and implants back into the prepectoral space. Although this technique failed during the early advent of breast reconstruction, newer technologies such as advances in fat grafting, improved acellular dermal matrices, better methods of assessing breast flap viability, and enhanced implants appear to have set the stage for the resurgence and positive early results seen with this technique...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29165610/gramene-2018-unifying-comparative-genomics-and-pathway-resources-for-plant-research
#4
Marcela K Tello-Ruiz, Sushma Naithani, Joshua C Stein, Parul Gupta, Michael Campbell, Andrew Olson, Sharon Wei, Justin Preece, Matthew J Geniza, Yinping Jiao, Young Koung Lee, Bo Wang, Joseph Mulvaney, Kapeel Chougule, Justin Elser, Noor Al-Bader, Sunita Kumari, James Thomason, Vivek Kumar, Daniel M Bolser, Guy Naamati, Electra Tapanari, Nuno Fonseca, Laura Huerta, Haider Iqbal, Maria Keays, Alfonso Munoz-Pomer Fuentes, Amy Tang, Antonio Fabregat, Peter D'Eustachio, Joel Weiser, Lincoln D Stein, Robert Petryszak, Irene Papatheodorou, Paul J Kersey, Patti Lockhart, Crispin Taylor, Pankaj Jaiswal, Doreen Ware
Gramene (http://www.gramene.org) is a knowledgebase for comparative functional analysis in major crops and model plant species. The current release, #54, includes over 1.7 million genes from 44 reference genomes, most of which were organized into 62,367 gene families through orthologous and paralogous gene classification, whole-genome alignments, and synteny. Additional gene annotations include ontology-based protein structure and function; genetic, epigenetic, and phenotypic diversity; and pathway associations...
November 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29165594/revisiting-fis-fst-wahlund-effects-and-null-alleles
#5
Thierry De Meeûs
Null alleles and Wahlund effects are well known causes of heterozygote deficits in empirical population genetics studies as compared to Hardy-Weinberg genotypic expectations. Some authors have theoretically studied the relationship of Wright's FIS computed from subsamples displaying a Wahlund effect and FST before the Wahlund effect, as can occasionally be obtained from populations of long-lived organisms. In the two subsample case, a positive relationship between these two parameters across loci would represent a signature of Wahlund effects...
November 20, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/29164434/isolated-cutaneous-granuloma-caused-by-candida-glabrata-a-rare-case-report-and-literature-review
#6
REVIEW
Yibin Fan, Weili Pan, Guizhen Wang, Youming Huang, Yali Li, Wei Fang, Xiaohua Tao
The incidence of candidiasis due to non-albicans Candida species (especially Candida glabrata) has significantly increased in recent decades. Candida glabrata often invades immunocompromised hosts and causes systemic or mucosal infections, whereas cutaneous infections are rarely reported. We present a rare case of cutaneous infection caused by C. glabrata and review all similar cases available in the PubMed database. A patient was admitted to the hospital with a 2-month history of a plaque on the face. Histopathological examination displayed typical infectious granulomas in the deep dermis, and the pathogen was finally confirmed as C...
November 22, 2017: Mycopathologia
https://www.readbyqxmd.com/read/29164102/anti-tumor-and-anti-angiogenic-ergosterols-from-ganoderma-lucidum
#7
Shaodan Chen, Tianqiao Yong, Yifang Zhang, Jiyan Su, Chunwei Jiao, Yizhen Xie
This study was carried out to isolate chemical constituents from the lipid enriched fraction of Ganoderma lucidum extract and to evaluate their anti-proliferative effect on tumor cells and human umbilical vein endothelial cells (HUVECs). Ergosterol derivatives (1-14) were isolated and purified from the lipid enriched fraction of G. lucidum. Their chemical structures were established by spectroscopic analyses or by comparison of mass and NMR spectral data with those reported previously. Amongst, compound 1 was purified and identified as a new one...
2017: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29163613/a-comparison-of-petiole-hydraulics-and-aquaporin-expression-in-an-anisohydric-and-isohydric-cultivar-of-grapevine-in-response-to-water-stress-induced-cavitation
#8
Megan C Shelden, Rebecca Vandeleur, Brent N Kaiser, Stephen D Tyerman
We report physiological, anatomical and molecular differences in two economically important grapevine (Vitis vinifera L.) cultivars cv. Grenache (near-isohydric) and Chardonnay (anisohydric) in their response to water-stress induced cavitation. The aim of the study was to compare organ vulnerability (petiole and stem) to cavitation by measuring ultrasonic acoustic emissions (UAE) and percent loss of conductance of potted grapevines subject to the onset of water-stress. Leaf (ψL) and stem water potential (ψS), stomatal conductance (gs), transpiration (E), petiole hydraulics (KPet), and xylem diameter were also measured...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163556/identification-of-mshsp20-gene-family-in-malus-sieversii-and-functional-characterization-of-mshsp16-9-in-heat-tolerance
#9
Meiling Yang, Yunxiu Zhang, Huanhuan Zhang, Hongbin Wang, Tao Wei, Shiyou Che, Lipeng Zhang, Baoquan Hu, Hong Long, Wenqin Song, Weiwei Yu, Guorong Yan
Heat shock proteins (Hsps) are common molecular chaperones present in all plants that accumulate in response to abiotic stress. Small heat shock proteins (sHsps) play important roles in alleviating diverse abiotic stresses, especially heat stress. However, very little is known about the MsHsp20 gene family in the wild apple Malus sieversii, a precious germplasm resource with excellent resistance characteristics. In this study, 12 putative M. sieversii Hsp20 genes were identified from RNA-Seq data and analyzed in terms of gene structure and phylogenetic relationships...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163529/nlrp10-enhances-cd4-t-cell-mediated-ifn%C3%AE-response-via-regulation-of-dendritic-cell-derived-il-12-release
#10
Maurizio Vacca, Julia Böhme, Lia Paola Zambetti, Hanif Javanmard Khameneh, Bhairav S Paleja, Federica Laudisi, Adrian W S Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Amit Singhal, Alessandra Mortellaro
NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products. Here, we generated a Nlrp10(-/-) mouse to delineate the role of NLRP10 in the host immune response and found that Nlrp10(-/-) dendritic cells (DCs) elicited sub-optimal IFNγ production by antigen-specific CD4(+) T cells compared to wild-type (WT) DCs. In response to T-cell encounter, CD40 ligation or Toll-like receptor 9 stimulation, Nlrp10(-/-) DCs produced low levels of IL-12, due to a substantial decrease in NF-κB activation...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163505/il17escan-a-tool-for-the-identification-of-peptides-inducing-il-17-response
#11
Sudheer Gupta, Parul Mittal, Midhun K Madhu, Vineet K Sharma
IL-17 cytokines are pro-inflammatory cytokines and are crucial in host defense against various microbes. Induction of these cytokines by microbial antigens has been investigated in the case of ischemic brain injury, gingivitis, candidiasis, autoimmune myocarditis, etc. In this study, we have investigated the ability of amino acid sequence of antigens to induce IL-17 response using machine-learning approaches. A total of 338 IL-17-inducing and 984 IL-17 non-inducing peptides were retrieved from Immune Epitope Database...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163333/mutation-analysis-of-consanguineous-moroccan-patients-with-parkinson-s-disease-combining-microarray-and-gene-panel
#12
Ahmed Bouhouche, Christelle Tesson, Wafaa Regragui, Mounia Rahmani, Valérie Drouet, Houyam Tibar, Zouhayr Souirti, Rafiqua Ben El Haj, Naima Bouslam, Mohamed Yahyaoui, Alexis Brice, Ali Benomar, Suzanne Lesage
During the last two decades, 15 different genes have been reported to be responsible for the monogenic form of Parkinson's disease (PD), representing a worldwide frequency of 5-10%. Among them, 10 genes have been associated with autosomal recessive PD, with PRKN and PINK1 being the most frequent. In a cohort of 145 unrelated Moroccan PD patients enrolled since 2013, 19 patients were born from a consanguineous marriage, of which 15 were isolated cases and 4 familial. One patient was homozygous for the common LRRK2 G2019S mutation and the 18 others who did not carry this mutation were screened for exon rearrangements in the PRKN gene using Affymetrix Cytoscan HD microarray...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29163314/dual-routes-and-the-cost-of-determining-least-costs
#13
Steven Phillips, Yuji Takeda, Fumie Sugimoto
Theories of cognition that posit complementary dual-route processes afford better fits to the data when each route explains a part of the data not explained by the other route. However, such theories must also explain why each route is invoked, lest one can fit any data set with enough alternatives. One possible explanation is that route selection is based on a least-cost principle: the route that requires fewer cognitive resources (including time) relative to the goal at hand. We investigated this explanation with a dual-display version of visual search, where the target could be identified via opposing (easy or hard forms of) feature and conjunction search conditions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29163118/semi-automated-anatomical-labeling-and-inter-subject-warping-of-high-density-intracranial-recording-electrodes-in-electrocorticography
#14
Liberty S Hamilton, David L Chang, Morgan B Lee, Edward F Chang
In this article, we introduce img_pipe, our open source python package for preprocessing of imaging data for use in intracranial electrocorticography (ECoG) and intracranial stereo-EEG analyses. The process of electrode localization, labeling, and warping for use in ECoG currently varies widely across laboratories, and it is usually performed with custom, lab-specific code. This python package aims to provide a standardized interface for these procedures, as well as code to plot and display results on 3D cortical surface meshes...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/29162852/predicting-nosocomial-lower-respiratory-tract-infections-by-a-risk-index-based-system
#15
Yong Chen, Xue Shan, Jingya Zhao, Xuelin Han, Shuguang Tian, Fangyan Chen, Xueting Su, Yansong Sun, Liuyu Huang, Hajo Grundmann, Hongyuan Wang, Li Han
Although belonging to one of the most common type of nosocomial infection, there was currently no simple prediction model for lower respiratory tract infections (LRTIs). This study aims to develop a risk index based system for predicting nosocomial LRTIs based on data from a large point-prevalence survey. Among the 49328 patients included, the prevalence of nosocomial LRTIs was 1.70% (95% confidence interval [CI], 1.64% to 1.76%). The areas under the receiver operating characteristic (ROC) curve for logistic regression and fisher discriminant analysis were 0...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162797/3d-collagen-architecture-induces-a-conserved-migratory-and-transcriptional-response-linked-to-vasculogenic-mimicry
#16
D O Velez, B Tsui, T Goshia, C L Chute, A Han, H Carter, S I Fraley
The topographical organization of collagen within the tumor microenvironment has been implicated in modulating cancer cell migration and independently predicts progression to metastasis. Here, we show that collagen matrices with small pores and short fibers, but not Matrigel, trigger a conserved transcriptional response and subsequent motility switch in cancer cells resulting in the formation of multicellular network structures. The response is not mediated by hypoxia, matrix stiffness, or bulk matrix density, but rather by matrix architecture-induced β1-integrin upregulation...
November 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/29162558/surgical-interventions-for-the-treatment-of-supracondylar-humerus-fractures-in-children-protocol-of-a-systematic-review
#17
Oreste Lemos Carrazzone, João Carlos Belloti, Fabio Teruo Matsunaga, Nacime Salomão Barbachan Mansur, Marcelo Hide Matsumoto, Flavio Faloppa, Marcel Jun Sugawara Tamaoki
BACKGROUND: The treatment of supracondylar humerus fracture in children (SHFC) is associated with complications such as functional deficit, residual deformity, and iatrogenic neurological damage. The standard treatment is closed reduction and percutaneous Kirschner wire fixation with different configurations. Despite this fact, there is still no consensus on the most effective technique for the treatment of these fractures. OBJECTIVE: The aim of this systematic review will be to evaluate the effect of surgical interventions on the treatment of Gartland type II and III SHFC by assessing function, complications, and error as primary outcomes...
November 21, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29162308/a-novel-series-of-enoyl-reductase-inhibitors-targeting-the-eskape-pathogens-staphylococcus-aureus-and-acinetobacter-baumannii
#18
Jieun Kwon, Tina Mistry, Jinhong Ren, Michael E Johnson, Shahila Mehboob
S. aureus and A. baumannii are among the ESKAPE pathogens that are increasingly difficult to treat due to the rise in the number of drug resistant strains. Novel therapeutics targeting these pathogens are much needed. The bacterial enoyl reductase (FabI) is as potentially significant drug target for developing pathogen-specific antibiotics due to the presence of alternate FabI isoforms in many other bacterial species. We report the identification and development of a novel N-carboxy pyrrolidine scaffold targeting FabI in S...
November 11, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29161861/a-mathematical-model-for-the-seasonal-transmission-of-schistosomiasis-in-the-lake-and-marshland-regions-of-china
#19
Yingke Li, Zhidong Teng, Shigui Ruan, Mingtao Li, Xiaomei Feng
Schistosomiasis, a parasitic disease caused by \textit{ Schistosoma Japonicum}, is still one of the most serious parasitic diseases in China and remains endemic in seven provinces, including Hubei, Anhui, Hunan, Jiangsu, Jiangxi, Sichuan, and Yunnan. The monthly data of human schistosomiasis cases in Hubei, Hunan, and Anhui provinces (lake and marshland regions) released by the Chinese Center for Disease Control and Prevention (China CDC) display a periodic pattern with more cases in late summer and early autumn...
October 2017: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/29161743/pharmacological-foundations-of-cannabis-chemovars
#20
Mark A Lewis, Ethan B Russo, Kevin M Smith
An advanced Mendelian Cannabis breeding program has been developed utilizing chemical markers to maximize the yield of phytocannabinoids and terpenoids with the aim to improve therapeutic efficacy and safety. Cannabis is often divided into several categories based on cannabinoid content. Type I, Δ(9)-tetrahydrocannabinol-predominant, is the prevalent offering in both medical and recreational marketplaces. In recent years, the therapeutic benefits of cannabidiol have been better recognized, leading to the promotion of additional chemovars: Type II, Cannabis that contains both Δ(9)-tetrahydrocannabinol and cannabidiol, and cannabidiol-predominant Type III Cannabis...
November 21, 2017: Planta Medica
keyword
keyword
93571
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"