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https://www.readbyqxmd.com/read/28918567/expansion-of-parents-undetermined-experience-in-socioeducational-programs-extending-the-dialogical-self-theory
#1
Dany Boulanger
The Dialogic Self Theory (DST-Hermans et al. Integrative Psychology and Behavioral Sciences, 51(4), 1-31, 2017) is extended here in its dynamic aspects through focusing on the notions of indeterminacy, emptiness and movement. Linking with Husserl, I propose moving the dialogical self (DS) from a clear position in the "repertory of the Self" to an undetermined horizon. This makes it possible to introduce "holes" (emptiness) into the schematic representation of the "repertory of the Self". Yet Husserl's concept of horizon seems to focus too much on making the indeterminable determinate...
September 16, 2017: Integrative Psychological & Behavioral Science
https://www.readbyqxmd.com/read/28913650/does-levonorgestrel-releasing-intrauterine-system-increase-breast-cancer-risk-in-peri-menopausal-women-an-hmo-perspective
#2
Nava Siegelmann-Danieli, Itzhak Katzir, Janet Vesterman Landes, Yaakov Segal, Rachel Bachar, Hadas Rotem Rabinovich, Martin Bialik, Joseph Azuri, Avi Porath, Yossef Lomnicky
PURPOSE: To evaluate the association between levonorgestrel-releasing intrauterine system (LNG-IUS) use and breast cancer (BC) risk. METHODS: A cohort of all Maccabi Healthcare Services (MHS) female members aged 40-50 years between 1/2003 and 12/2013 was used to identify LNG-IUS users as "cases," and 2 age-matched non-users as "controls." Exclusion criteria included: prior BC diagnosis, prior (5 years pre-study) and subsequent treatment with other female hormones or prophylactic tamoxifen...
September 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28913157/non-functioning-gastroenteropancreatic-gep-tumors-a-111-in-pentetreotide-spect-ct-diagnostic-study
#3
Angela Spanu, Orazio Schillaci, Bastiana Piras, Diego F Calvisi, Antonio Falchi, Roberta Danieli, Susanna Nuvoli, Franca Dore, Giuseppe Madeddu
In a retrospective study performed in non-functioning GEP tumor patients we further investigated (111)In-Pentetreotide SPECT/CT usefulness in diagnosis, staging and follow-up also evaluating whether the procedure may give more information than conventional imaging procedures (CIP), such as CT, MRI, US. We enrolled 104 consecutive patients with non-functioning GEP tumors, 30 in initial diagnosis and staging phases (IDS) and 74 in follow-up (FU). All patients underwent somatostatin receptor scintigraphy (SRS) whole body scan at 4, 24 and, if necessary, 48 hours followed by abdominal and chest SPECT/CT after (111)In-Pentetreotide 148-222 MBq i...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28912904/fasciatherapy-and-reflexology-compared-to-hypnosis-and-music-therapy-in-daily-stress-management
#4
Bernard Payrau, Nadine Quere, Elisabeth Breton, Christine Payrau
BACKGROUND: Patients suffering from stress symptoms due to every-day life who are looking for a non-pharmacological response to their relief expectation are many. Furthermore, early reckoning of the day-to-day stress which may lead to clinical diagnosis is the best way of preventing the stress-related diseases. Among the many alternative medicinal options, there is little evidence that fasciatherapy (Fs) and reflexology (Rf) are effective in this field. PURPOSE: assess incidence of fasciatherapy Danis Bois Method (DBM) and of reflexology on patients' stress level in everyday-life, and provide a more informed choice among the numerous mind and body techniques by comparing them with hypnosis (Hp) and music therapy (Mt)...
September 2017: International Journal of Therapeutic Massage & Bodywork
https://www.readbyqxmd.com/read/28910658/postural-regulatory-strategies-during-quiet-sitting-are-affected-in-individuals-with-thoracic-spinal-cord-injury
#5
Matija Milosevic, Dany H Gagnon, Philippe Gourdou, Kimitaka Nakazawa
Thoracic spinal cord injury (SCI) can have significant negative consequences, which can affect the ability to maintain unsupported sitting. The objectives of this study were to compare postural control of individuals with high- and low-thoracic SCI to able-bodied people and evaluate the effects of upper-limb support on postural control during quiet sitting. Twenty-five individuals were recruited into: (a) high-thoracic SCI; (b) low-thoracic SCI; and (c) able-body subgroups. Participants were seated and asked to maintain a steady balance in the following postures: (1) both hands resting on thighs; (2) both arms crossed over the chest; and (3) both arms extended...
August 31, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28906284/effect-of-transfusion-on-mortality-and-other-adverse-events-among-critically-ill-septic-patients-an-observational-study-using-a-marginal-structural-cox-model
#6
Claire Dupuis, Maité Garrouste-Orgeas, Sébastien Bailly, Christophe Adrie, Dany Goldgran-Toledano, Elie Azoulay, Stéphane Ruckly, Guillaume Marcotte, Bertrand Souweine, Michael Darmon, Yves Cohen, Carole Schwebel, Guillaume Lacave, Lila Bouadma, Jean-Francois Timsit
OBJECTIVES: RBC transfusion is often required in patients with sepsis. However, adverse events have been associated with RBC transfusion, raising safety concerns. A randomized controlled trial validated the 7 g/dL threshold, but previously transfused patients were excluded. Cohort studies led to conflicting results and did not handle time-dependent covariates and history of treatment. Additional data are thus warranted to guide patient's management. DESIGN: To estimate the effect of one or more RBC within 1 day on three major outcomes (mortality, ICU-acquired infections, and severe hypoxemia) at day 30, we used marginal structural models...
September 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28904258/prevalence-of-work-related-musculoskeletal-disorders-among-sonographers-in-china-results-from-a-national-web-based-survey
#7
Danying Zhang, Hanlin Huang
OBJECTIVES: The aims of present study were to determine the prevalence of work-related musculoskeletal disorders (WRMSDs) among sonographers in China and to provide evidence for appropriate intervention measures to be taken. METHODS: A self-reported questionnaire was used to screen WRMSDs experienced by sonographers during the past 12 months. This questionnaire survey was created and hosted on the WeChat official account platform for sonographers. RESULTS: In the present study, 567 sonographers from 521 medical institutions completed the questionnaire...
September 13, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28904003/preclinical-pharmacology-and-pharmacokinetics-of-inhaled-hexadecyl-treprostinil-c16tr-a-pulmonary-vasodilator-prodrug
#8
Michel R Corboz, Zhili Li, Vladimir Malinin, Adam J Plaunt, Donna M Konicek, Franziska G Leifer, Kuan-Ju Chen, Charles E Laurent, Han Yin, Marzena C Biernat, Dany Salvail, Jianguo Zhuang, Fadi Xu, Aidan Curran, Walter R Perkins, Richard W Chapman
This report describes the preclinical pharmacology and pharmacokinetics (PK) of hexadecyl-treprostinil (C16TR), a prodrug of treprostinil (TRE), formulated in a lipid nanoparticle (LNP) for inhalation as a pulmonary vasodilator. C16TR showed no activity (> 10 µM) in receptor binding and enzyme inhibition assays including binding to EP2, DP1, IP and EP4; TRE potently bound to each of these prostanoid receptors. C16TR had no effect (up to 200 nM) on platelet aggregation induced by adenosine diphosphate (ADP) in rat blood...
September 13, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/28903627/reliability-and-minimal-detectable-change-of-a-new-treadmill-based-progressive-workload-incremental-test-to-measure-cardiorespiratory-fitness-in-manual-wheelchair-users
#9
Cindy Gauthier, Jasmine Arel, Rachel Brosseau, Audrey L Hicks, Dany H Gagnon
Background Cardiorespiratory fitness training is commonly provided to manual wheelchair users (MWUs) in rehabilitation and physical activity programs, emphasizing the need for a reliable task-specific incremental wheelchair propulsion test. Objective Quantifying test-retest reliability and minimal detectable change (MDC) of key cardiorespiratory fitness measures following performance of a newly developed continuous treadmill-based wheelchair propulsion test (WPTTreadmill). Methods Twenty-five MWUs completed the WPTTreadmill on two separate occasions within one week...
September 13, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28900789/gradient-reconstitution-of-membrane-proteins-for-solid-state-nmr-studies
#10
Denis Lacabanne, Alons Lends, Clément Danis, Britta Kunert, Marie-Laure Fogeron, Vlastimil Jirasko, Claire Chuilon, Lauriane Lecoq, Cédric Orelle, Vincent Chaptal, Pierre Falson, Jean-Michel Jault, Beat H Meier, Anja Böckmann
We here adapted the GRecon method used in electron microscopy studies for membrane protein reconstitution to the needs of solid-state NMR sample preparation. We followed in detail the reconstitution of the ABC transporter BmrA by dialysis as a reference, and established optimal reconstitution conditions using the combined sucrose/cyclodextrin/lipid gradient characterizing GRecon. We established conditions under which quantitative reconstitution of active protein at low lipid-to-protein ratios can be obtained, and also how to upscale these conditions in order to produce adequate amounts for NMR...
September 12, 2017: Journal of Biomolecular NMR
https://www.readbyqxmd.com/read/28900430/prins-non-coding-rna-regulates-nucleic-acid-induced-innate-immune-responses-of-human-keratinocytes
#11
Judit Danis, Anikó Göblös, Zsuzsanna Bata-Csörgő, Lajos Kemény, Márta Széll
Cytosolic DNA fragments are recognized as pathogen- and danger-associated molecular patterns that induce a cascade of innate immune responses. Moreover, excessive cytosolic DNA can enhance chronic inflammation, predominantly by activating inflammasomes, and thereby contributing to the pathogenesis of chronic diseases, such as psoriasis. Psoriasis associated non-protein coding RNA induced by stress (PRINS) is a long non-coding RNA, which has been shown to be associated with psoriasis susceptibility and cellular stress responses; however, the precise mechanism of its action has not been determined...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28899285/predicting-rehabilitation-length-of-stay-in-canada-it-s-not-just-about-impairment
#12
B Catharine Craven, Dilnur Kurban, Farnoosh Farahani, Carly S Rivers, Chester Ho, A Gary Linassi, Dany H Gagnon, Colleen O'Connell, Karen Ethans, Laurent J Bouyer, Vanessa K Noonan
INTRODUCTION: Current tertiary Spinal Cord Injury (SCI) rehabilitation funding and rehabilitation length of stay (R-LOS) in most North American jurisdictions are linked to an individual's impairment. Our objectives were to: 1) describe the impact of relevant demographic, impairment and medical complexity variables at rehabilitation admission on R-LOS among adult Canadians with traumatic SCI; and 2) identify factors which extend R-LOS. METHODS: Data from 1,376 adults with traumatic SCI were obtained via chart abstraction and administrative data linkage from 15 Rick Hansen SCI Registry sites (2004-2014)...
September 12, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28898406/dc-sign-reacts-with-tlr4-and-regulates-inflammatory-cytokine-expression-via-nf-%C3%AE%C2%BAb-activation-in-renal-tubular-epithelial-cells-during-acute-renal-injury
#13
Danying Feng, Yanping Wang, Yan Liu, Liping Wu, Xiao Li, Yufan Chen, Yuanyuan Chen, Yafeng Chen, Chundi Xu, Ke Yang, Tong Zhou
In the pathological process of acute kidney injury (AKI), innate immune receptors are essential in inflammatory response modulation; however, the precise molecular mechanisms are still unclear. Our study sought to demonstrate the inflammatory response mechanisms in renal tubular epithelial cells via Toll-like receptor 4 (TLR4) and dendritic cell-specific ICAM-3-grabbing non-integrin 1 (DC-SIGN) signaling. We found that DC-SIGN exhibited strong expression in renal tubular epithelial cells of human acute renal injury tissues...
September 12, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28888035/analysis-of-earthworm-sub-lethal-toxic-responses-to-atrazine-exposure-using-1-h-nuclear-magnetic-resonance-nmr-based-metabolomics
#14
Vivek D Dani, André J Simpson, Myrna J Simpson
Atrazine toxicity to earthworms is still not fully understood, particularly at sub-lethal concentrations. Because of the ubiquity of atrazine in the environment, it is imperative to understand the impacts of atrazine presence on soil-dwelling organisms. To examine this in detail, we used (1) H nuclear magnetic resonance (NMR)-based metabolomics to elucidate earthworm (Eisenia fetida) responses after a 48 h of atrazine exposure in contact tests. Earthworms were exposed to four sub-lethal concentrations of 362...
September 9, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28885340/a-case-report-of-lung-adenocarcinoma-with-polyserous-effusions-as-the-onset-symptom
#15
Ping Han, Ruipin Yao, Dongxia Zhai, Chao Cheng, Fangyong Yang, Shuai Sun, Danying Zhang, Chaoqin Yu
RATIONALE: Coexistence of lung adenocarcinoma and polyserous effusions is quite rare. This complexity of etiology adds difficulty to the diagnosis and is likely to cause misdiagnosis and maldiagnosis. PATIENT CONCERNS: A 43-year-old woman was admitted with symptoms of dry cough, chest suffocation, polyserous effusions, and generalized edema. Only a small number of heterocysts were detected in the ascites, and malignant cells were detected in the pleural and pericardial effusions...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28885155/a-nonlinear-dynamics-based-estimator-for-functional-electrical-stimulation-preliminary-results-from-lower-leg-extension-experiments
#16
Marcus Allen, Qiang Zhong, Nicholas Kirsch, Ashwin Dani, William W Clark, Nitin Sharma
Miniature inertial measurement units (IMUs) are wearable sensors that measure limb segment or joint angles during dynamic movements. However, IMUs are generally prone to drift, external magnetic interference, and measurement noise. This paper presents a new class of nonlinear state estimation technique called state-dependent coefficient (SDC) estimation to accurately predict joint angles from IMU measurements. The SDC estimation method uses limb dynamics, instead of limb kinematics, to estimate the limb state...
September 7, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28882094/competing-risks-modeling-of-cumulative-effects-of-time-varying-drug-exposures
#17
Coraline Danieli, Michal Abrahamowicz
An accurate assessment of drug safety or effectiveness in pharmaco-epidemiology requires defining an etiologically correct time-varying exposure model, which specifies how previous drug use affects the hazard of the event of interest. An additional challenge is to account for the multitude of mutually exclusive events that may be associated with the use of a given drug. To simultaneously address both challenges, we develop, and validate in simulations, a new approach that combines flexible modeling of the cumulative effects of time-varying exposures with competing risks methodology to separate the effects of the same drug exposure on different outcomes...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28878243/the-environmental-impacts-of-one-of-the-largest-tailing-dam-failures-worldwide
#18
Vanessa Hatje, Rodrigo M A Pedreira, Carlos Eduardo de Rezende, Carlos Augusto França Schettini, Gabriel Cotrim de Souza, Danieli Canaver Marin, Peter Christian Hackspacher
The impacts of the SAMARCO iron tailing spill along more than 650 km, between the dam and the plume of the Doce River in the Atlantic, were assessed by the determination of toxic metals. The tailing spill caused a substantial increase in suspended sediment loads (up to 33,000 mg L(-1)), in addition to large depositions of waste along the Doce basin. The highest estimated transport of dissolved metals was observed for Fe (58.8 μg s(-1)), Ba (37.9 μg s(-1)) and Al (25.0 μg s(-1)). Sediments reached the highest enrichment factors (EFs) for Hg (4,234), Co (133), Fe (43), and Ni (16), whereas As (55), Ba (64), Cr (16), Cu (17), Mn (41), Pb (38) and Zn (82) highest EFs were observed for suspended particulate matter (SPM)...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28873789/effectiveness-of-service-dogs-for-veterans-with-ptsd-preliminary-outcomes
#19
Claude Vincent, Geneviève Belleville, Dany H Gagnon, Frédéric Dumont, Edouard Auger, Vicky Lavoie, Markus Besemann, Noël Champagne, Geneviève Lessart
Limited scientific evidence on the effectiveness of psychiatric service dogs used by Veterans with post-traumatic stress disorder (PTSD) is available. This study investigated their short-term effectiveness among 15 Canadian veterans who received a first psychiatric service dog. Preliminary results suggest potential beneficial effects at 3 months on the psychiatric symptoms.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28871983/phase-1-2-study-of-dual-energy-computed-tomography-for-assessment-of-pulmonary-function-in-radiation-therapy-planning
#20
Houda Bahig, Marie-Pierre Campeau, Andréanne Lapointe, Stephane Bedwani, David Roberge, Jacques de Guise, Danis Blais, Toni Vu, Louise Lambert, Carl Chartrand-Lefebvre, Martin Lord, Edith Filion
PURPOSE: To quantify lung function according to a dual-energy computed tomography (DECT)-derived iodine map in patients treated with radiation therapy for lung cancer, and to assess the dosimetric impact of its integration in radiation therapy planning. METHODS AND MATERIALS: Patients treated with stereotactic ablative radiation therapy for early-stage or intensity modulated radiation therapy for locally advanced lung cancer were prospectively enrolled in this study...
October 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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