Luiza Helena Falleiros-Arlant, Silvia E González Ayala, Carla Domingues, Jose Brea, Agustín De Colsa-Ranero
Oral poliovirus vaccine (OPV) has been instrumental in controlling the polio epidemic, and stands out for its safety, efficacy, ease of oral administration, and low cost. However, despite these advantages, as it is a live attenuated virus vaccine, there is the possibility of mutations that confer neurovirulence. Therefore, surveillance for acute flaccid paralysis (AFP) is important, whether associated with live vaccines (VAPP) or vaccine-derived viruses (VDPV). In this review we present important data from Latin America in recent years, where data on VDPV of community transmission, of ambiguous origin and associated with immunodeficiencies are reviewed...
December 2020: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología