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CPP-ACP

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https://www.readbyqxmd.com/read/28052211/cpp-acp-effect-on-dental-plaque-acidity-after-water-rinsing-following-topical-fluoride-therapy
#1
Mazhari Fatemeh, Sharifi Marjan, Noorollahian Homa, Sharifi Mahsa
OBJECTIVES: There is some evidence that water rinsing immediately after topical fluoride therapy has the potential to reduce the effectiveness of fluoride. The aim was to determine if covering fluoridated teeth with a layer of mousse containing CPP-ACP could prevent the adverse effect of rinsing on fluoride and consequently its buffering effect on dental plaque pH during cariogenic challenge. STUDY DESIGN: This randomized, controlled, crossover, in situ study was conducted on 25 participants...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28045314/efficacy-of-a-casein-phosphopeptide-amorphous-calcium-phosphate-cpp-acp-paste-in-preventing-white-spot-lesions-in-patients-with-fixed-orthodontic-appliances-a-prospective-clinical-trial
#2
E Esenlik, E Uzer Çelik, E Bolat
AIM: The aim of this prospective study was to test the efficacy of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste applied in-office to prevent white spot lesions (WSL) in patients undergoing fixed orthodontic treatment. MATERIALS AND METHODS: Study design: this study was designed as a randomised controlled clinical trial. Fifty-seven patients undergoing nonextraction fixed orthodontic treatment were enrolled and divided randomly into two groups (control n = 28, experimental n = 29)...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28032049/the-efficiency-of-child-formula-dentifrices-containing-different-calcium-and-phosphate-compounds-on-artificial-enamel-caries
#3
Praphasri Rirattanapong, Kadkao Vongsavan, Chavengkiat Saengsirinavin, Ploychompoo Khumsub
OBJECTIVES: Fluoride toothpaste has been extensively used to prevent dental caries. However, the risk of fluorosis is concerning, especially in young children. Calcium phosphate has been an effective remineralizing agent and is present in commercial dental products, with no risk of fluorosis to users. This in vitro study aimed to compare the effects of different calcium phosphate compounds and fluoride-containing dentifrices on artificial caries in primary teeth. MATERIALS AND METHODS: Fifty sound primary incisors were coated with nail varnish, leaving two 1 mm(2) windows on the labial surface before immersion in demineralizing solution for 96 hours to produce artificial enamel lesions...
November 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28024772/effects-of-casein-phosphopeptide-amorphous-calcium-phosphate-application-after-interproximal-stripping-on-enamel-surface-an-in-vivo-study
#4
Mehmet Bayram, Adem Kusgoz, Cemal Yesilyurt, Metin Nur
INTRODUCTION: The aim of this study was to investigate the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) application after interproximal stripping on enamel surface structures in vivo. METHODS: Fifteen patients with a mean age of 15.8 years participated in this study. For each patient, the extraction of 4 first premolars was part of the orthodontic treatment plan. The patients were randomly divided into 5 groups of 3 patients. With the exception of group 1, the mesial and distal surfaces of all first premolars were stripped with a stripping disc (Komet; Gebr Brasseler, Lemgo, Germany) under air cooling and then polished with Sof-Lex polishing discs (3M Dental Products, St Paul, Minn)...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27939657/prevention-of-secondary-caries-using-silver-diamine-fluoride-treatment-and-casein-phosphopeptide-amorphous-calcium-phosphate-modified-glass-ionomer-cement
#5
Irene Shuping Zhao, May Lei Mei, Michael F Burrow, Edward Chin-Man Lo, Chun-Hung Chu
OBJECTIVE: To study the effect of silver diamine fluoride (SDF) treatment and incorporating casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into a glass-ionomer cement (GIC) to prevent secondary caries. METHOD: A cervical cavity was prepared on 32 premolars for the following restoration groups: group 1, conventional GIC restoration; group 2, SDF (38%) treatment and conventional GIC restoration; group 3, CPP-ACP (3%) modified GIC; and group 4, SDF treatment and CPP-ACP modified GIC...
December 6, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27891308/comparative-evaluation-of-the-efficacy-of-fluoride-varnish-and-casein-phosphopeptide-amorphous-calcium-phosphate-in-reducing-streptococcus-mutans-counts-in-dental-plaque-of-children-an-in-vivo-study
#6
Shweta Chandak, Ashish Bhondey, Amit Bhardwaj, Jitesh Pimpale, Manisha Chandwani
AIM: To assess the comparative efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complex visa viz. Streptococcus mutans in plaque, and thereby the role that these two agents could play in the prevention of dental caries. MATERIALS AND METHODS: A cluster sample of 120 caries inactive individuals belonging to moderate and high caries risk group were selected from 3-5-year-old age group based on the criteria given by Krassee and were randomized to four groups, namely, fluoride varnish - Group I, CPP-ACP complex - Group II, mixture of CPP-ACP complex -Gourp III, and fluoride and routine oral hygiene procedures as control - Group IV...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27843950/a-12-week-assessment-of-the-treatment-of-white-spot-lesions-with-cpp-acp-paste-and-or-fluoride-varnish
#7
Zeynep Aslı Güçlü, Alev Alaçam, Nichola Jayne Coleman
This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the first month (FV); twice daily self-applications of CPP-ACP paste (CPP-ACP); weekly applications of fluoride varnish for the first month and twice daily self-applications of CPP-ACP paste (CPP-ACP-FV); and no intervention (control)...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27670292/effect-of-fluoride-varnish-with-added-casein-phosphopeptide-amorphous-calcium-phosphate-on-the-acid-resistance-of-the-primary-enamel
#8
Nuray Tuloglu, Sule Bayrak, Emine Sen Tunc, Fusun Ozer
BACKGROUND: This study aimed to investigate the effects of a fluoride varnish with added Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) treatments on acid resistance of primary teeth enamel. METHODS: Enamel specimens obtained from 40 primary incisors (for surface microhardness testing) and 40 primary molars (for demineralization depth measurement) were randomly divided into four groups (n = 10 incisors and 10 molars) each according to surface treatment: no treatment (control), MI varnish (1-8 % sodium fluoride and 1-5 % CPP-ACP), Clinpro White (1-5 % sodium fluoride and <5 % modified tricalcium phosphate), Duraphat (<5 % sodium fluoride)...
2016: BMC Oral Health
https://www.readbyqxmd.com/read/27627567/the-impact-of-selected-fluoridated-toothpastes-on-dental-erosion-in-profilometric-measurement
#9
COMPARATIVE STUDY
Katarzyna Fita, Urszula Kaczmarek
BACKGROUND: Some fluoridated toothpastes, available commercially, are described to have a protective effect against dental erosion. OBJECTIVES: To evaluate the influence of the selected marketed toothpastes on the human enamel exposed to acid beverages. MATERIAL AND METHODS: Enamel specimens from extracted human teeth were prepared (n = 40). Specimens were randomly divided into 10 experimental groups, 4 specimens each, which were subjected to acid challenge for 10 min using orange juice (pH 3...
March 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27617382/comparison-of-cpp-acp-tri-calcium-phosphate-and-hydroxyapatite-on-remineralization-of-artificial-caries-like-lesions-on-primary-enamel-an-in-vitro-study
#10
COMPARATIVE STUDY
Meghna Bajaj, P Poornima, S Praveen, N B Nagaveni, K B Roopa, I E Neena, K P Bharath
OBJECTIVES: To compare CPP-ACP, Tri-calcium phosphate and Hydroxyapatite on remineralization of artificial caries like lesions on primary enamel. STUDY DESIGN: Ten extracted Primary molars coated with nail varnish, leaving a window of 2×4 mm on buccal and lingual surface were immersed in demineralizing solution for 96 hours and sectioned longitudinally to obtain 40 sections (4 sections per tooth) and were randomly divided into 4 groups (A to D) n=10; Group A: negative control, Group B: CPP-ACP, Group C: Tri-calcium phosphate, Group D: Hydroxyapatite...
2016: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27613394/effect-of-surface-treatments-on-the-mechanical-properties-and-antimicrobial-activity-of-desiccated-glass-ionomers
#11
Jennifer O Simmons, Erik J Meyers, Wen Lien, Rosalia L Banfield, Howard W Roberts, Kraig S Vandewalle
OBJECTIVES: The purpose of this study was to evaluate the effect of various surface treatments on the mechanical properties and antibacterial activity of desiccated glass-ionomer (GI) and resin-modified glass-ionomer (RMGI) materials. METHODS: One hundred GI and RMGI specimens were fabricated in a mold, stored in 100% humidity for 24h, placed in air to desiccate for 24h, and then stored for one week in one of the five media [casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), chlorhexidine (CHX), sodium fluoride (NaF), cetylpyridinium chloride (CPC), or 100% humidity (control)]...
September 6, 2016: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/27589264/casein-phosphopeptide-amorphous-calcium-phosphate-reduces-streptococcus-mutans-biofilm-development-on-glass-ionomer-cement-and-disrupts-established-biofilms
#12
Stuart G Dashper, Deanne V Catmull, Sze-Wei Liu, Helen Myroforidis, Ilya Zalizniak, Joseph E A Palamara, N Laila Huq, Eric C Reynolds
Glass ionomer cements (GIC) are dental restorative materials that are suitable for modification to help prevent dental plaque (biofilm) formation. The aim of this study was to determine the effects of incorporating casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) into a GIC on the colonisation and establishment of Streptococcus mutans biofilms and the effects of aqueous CPP-ACP on established S mutans biofilms. S. mutans biofilms were either established in flow cells before a single ten min exposure to 1% w/v CPP-ACP treatment or cultured in static wells or flow cells with either GIC or GIC containing 3% w/w CPP-ACP as the substratum...
2016: PloS One
https://www.readbyqxmd.com/read/27557918/effect-of-tooth-mousse-on-streptococcus-mutans-in-the-plaque-of-high-caries-risk-preschool-children-a-triple-blind-randomized-clinical-trial
#13
Amira N Fadl, Magda M ElTekeya, Karin L Dowidar, Nadia Mokhles, Maha M El Tantawi
PURPOSE: Control of Streptococcus mutans can prevent caries in high-risk preschool children. The purpose of this study was to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on Streptococcus mutans in the plaque of high-risk preschool children. METHODS: A triple blind, randomized, controlled clinical trial included 40 healthy three- to five-year-olds with at least one white spot lesion. They were randomized into test (daily applications of GC Tooth Mousse:CPP-ACP) and control groups (placebo mousse)...
2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/27504408/an-in-vitro-comparative-evaluation-of-three-remineralizing-agents-using-confocal-microscopy
#14
Krunal Chokshi, Achala Chokshi, Sapna Konde, Sunil Raj Shetty, Kumar Narayan Chandra, Sinjana Jana, Sanjana Mhambrey, Sneha Thakur
INTRODUCTION: The caries process has been thought to be irreversible, resulting in the permanent loss of tooth substance and eventually the development of a cavity. Recent approaches focused on application of remineralizing agents to incipient carious lesions, aim at controlling demineralization and promoting remineralization. Remineralizing agents create a supersaturated environment around the lesion; thus, preventing mineral loss and forces calcium and phosphate ions in the vacant areas...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27437352/assessment-of-white-spot-lesions-and-in-vivo-evaluation-of-the-effect-of-cpp-acp-on-white-spot-lesions-in-permanent-molars-of-children
#15
Deepti Munjal, Shalini Garg, Abhishek Dhindsa, Gagandeep Kaur Sidhu, Harsimran Singh Sethi
INTRODUCTION: As hindrance of remineralisation process occurs during orthodontic therapy resulting in decalcification of enamel because number of plaque retention sites increases due to banding and bonding of appliances to teeth. AIM: The present analytic study was undertaken to assess the occurrence of white spot lesions in permanent molars of children with and without orthodontic therapy and to evaluate the effect of Casein PhosphoPeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in post-orthodontic patients in a given period of time...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27430013/influence-of-calcium-phosphate-and-apatite-containing-products-on-enamel-erosion
#16
A Kensche, S Pötschke, C Hannig, G Richter, W Hoth-Hannig, M Hannig
For the purpose of erosion prevention the present study aimed to compare the efficacy of two biomimetic products and a fluoride solution to optimize the protective properties of the pellicle. After 1 min of in situ pellicle formation on bovine enamel slabs, 8 subjects adopted CPP-ACP (GC Tooth Mousse), a mouthwash with hydroxyapatite microclusters (Biorepair), or a fluoride based mouthwash (elmex Kariesschutz) for 1 min each. Afterwards, samples were exposed in the oral cavity for 28 min. Native enamel slabs and slabs exposed to the oral cavity for 30 min without any rinse served as controls...
2016: TheScientificWorldJournal
https://www.readbyqxmd.com/read/27403057/role-of-enamel-deminerlization-and-remineralization-on-microtensile-bond-strength-of-resin-composite
#17
Abbas Rizvi, Muhammad S Zafar, Yasser Al-Wasifi, Wamiq Fareed, Zohaib Khurshid
OBJECTIVE: This study is aimed to establish the microtensile bond strength of enamel following exposure to an aerated drink at various time intervals with/without application of remineralization agent. In addition, degree of remineralization and demineralization of tooth enamel has been assessed using polarized light microscopy. MATERIALS AND METHODS: Seventy extracted human incisors split into two halves were immersed in aerated beverage (cola drink) for 5 min and stored in saliva until the time of microtensile bond testing...
July 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/27383699/evaluation-of-the-remineralization-capacity-of-cpp-acp-containing-fluoride-varnish-by-different-quantitative-methods
#18
Selcuk Savas, Fevzi Kavrìk, Ebru Kucukyìlmaz
OBJECTIVE: The aim of this study was to evaluate the efficacy of CPP-ACP containing fluoride varnish for remineralizing white spot lesions (WSLs) with four different quantitative methods. MATERIAL AND METHODS: Four windows (3x3 mm) were created on the enamel surfaces of bovine incisor teeth. A control window was covered with nail varnish, and WSLs were created on the other windows (after demineralization, first week and fourth week) in acidified gel system. The test material (MI Varnish) was applied on the demineralized areas, and the treated enamel samples were stored in artificial saliva...
May 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27294918/the-interactions-of-cpp-acp-with-saliva
#19
Noorjahan Laila Huq, Helen Myroforidis, Keith J Cross, David P Stanton, Paul D Veith, Brent R Ward, Eric C Reynolds
The repair of early dental caries lesions has been demonstrated by the application of the remineralisation technology based on casein phosphopeptide-stabilised amorphous calcium phosphate complexes (CPP-ACP). These complexes consist of an amorphous calcium phosphate mineral phase stabilised and encapsulated by the self-assembly of milk-derived phosphopeptides. During topical application of CPP-ACP complexes in the oral cavity, the CPP encounters the enamel pellicle consisting of salivary proteins and peptides...
June 9, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27241671/in-situ-effect-of-chewing-gum-with-and-without-cpp-acp-on-enamel-surface-hardness-subsequent-to-ex-vivo-acid-challenge
#20
M C Jordão, C R B Alencar, I M Mesquita, M A R Buzalaf, A C Magalhães, M A A M Machado, H M Honório, D Rios
The erosion-protective effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is controversial. This study aimed to investigate the ability of CPP-ACP chewing gum to prevent a single event of erosive demineralization in situ. Bovine enamel blocks (n = 120) were randomly assigned to 3 phases according to the baseline surface hardness: phase I (PI) - chewing gum with CPP-ACP, phase II (PII) - chewing gum without CPP-ACP, and control phase (PIII) - salivary effect without stimulation (no gum). Nineteen volunteers participated in this study during 3 crossover phases of 2 h...
2016: Caries Research
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