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https://www.readbyqxmd.com/read/29679400/the-development-of-hoof-balance-and-landing-preference-in-the-postnatal-period
#1
B M C Gorissen, F M Serra Bragança, C F Wolschrijn, W Back, P R van Weeren
BACKGROUND: Foals can follow the herd within hours of birth, but it has been shown that kinetic gait parameters and static balance still have to mature. However, development of dynamic balance has not been investigated. OBJECTIVES: To objectively quantify landing and pressure pattern dynamics under the hoof during the first half year of life. STUDY DESIGN: Prospective, cohort study performed at a single stud farm. METHODS: Pressure plate measurements at walk and trot from ten Dutch warmblood foals during the first 24 weeks of life were used to quantify toe-heel and medial-lateral hoof balance asymmetry indexes and to determine preferred landing strategy...
April 20, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29679378/prominent-microglial-activation-in-cortical-white-matter-is-selectively-associated-with-cortical-atrophy-in-primary-progressive-aphasia
#2
Daniel T Ohm, Garam Kim, Tamar Gefen, Alfred Rademaker, Sandra Weintraub, Eileen Bigio, M-Marsel Mesulam, Emily Rogalski, Changiz Geula
AIMS: Primary progressive aphasia (PPA) is a clinical syndrome characterized by selective language impairments associated with focal cortical atrophy favouring the language dominant hemisphere. PPA is associated with Alzheimer's disease (AD), frontotemporal lobar degeneration (FTLD), and significant accumulation of activated microglia. Activated microglia can initiate an inflammatory cascade that may contribute to neurodegeneration, but their quantitative distribution in cortical white matter and their relationship with cortical atrophy are unknown...
April 21, 2018: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/29678489/impact-of-bone-volume-upon-condylar-activity-in-patients-with-unilateral-condylar-hyperplasia
#3
Luc H E Karssemakers, Jitske W Nolte, D Bram Tuinzing, Geerling E J Langenbach, Alfred G Becking, Pieter G Raijmakers
PURPOSE: Unilateral condylar hyperplasia or hyperactivity (UCH) is a bone overgrowth disorder affecting the mandible. The purpose of this study was to determine the relations among age, condylar bone structure, condylar bone volume, and condylar bone activity on single-photon emission computed tomographic (SPECT) scans in patients with UCH. MATERIALS AND METHODS: This study included 20 patients with a clinical presentation of progressive mandibular asymmetry and a positive bone SPECT scan...
March 28, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29677359/essential-infantile-esotropia-potential-pathogenetic-role-of-extended-subcortical-neuroplasticity
#4
Michael C Brodsky
Essential infantile esotropia is generated by prenuclear visual pathways that increase esotonus and gradually drive the eyes into a convergent position. Contrary to the prevailing notion that infantile esotropia reflects a primary disturbance within the visual cortex, accumulating evidence suggests that infantile esotropia is generated by lower subcortical centers that subserve nasalward optokinesis. These phylogenetically older visuo-vestibular pathways include the nucleus of the optic tract, accessory optic system, inferior olive, cerebellar flocculus, and vestibular nucleus...
April 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29676213/manual-asymmetry-in-older-adults-on-a-complex-coincidence-anticipation-task
#5
Paula Cristina Dos Santos Rodrigues, João Miguel Carvalho da Silva, João Manuel Pardal Barreiros, Maria Olga Fernandes Vasconcelos
Age-related asymmetrical functional decline was tested in a sample of 57 right-handed volunteers between 65 and 85 years of age. Participants performed a complex coincidence-anticipation (CA) task with both preferred and non-preferred hands. Results demonstrated that the proficiency of a complex CA task was similar for the 2 age groups, but different for the 2 hands. The non-preferred hand was more proficient for temporal accuracy but not for response timing, which was similar for both hands. Moreover, the lack of interaction between age and hand both in response timing and response accuracy reveal symmetric performance across ages...
April 20, 2018: Laterality
https://www.readbyqxmd.com/read/29675375/the-association-between-demodex-infestation-and-ocular-surface-manifestations-in-meibomian-gland-dysfunction
#6
Xiao-Bo Zhang, Ying-Hui Ding, Wei He
AIM: To investigate the association between ocular demodex folliculorum infestation and ocular surface manifestations in meibomian gland dysfunction (MGD). METHODS: Eight-six patients with MGD were enrolled. All enrolled subjects were tested in the following sequence: ocular surface disease index (OSDI), slit-lamp biomicroscope examination, corneal surface regularity index (SRI) and surface asymmetry index (SAI), tear fluid collection, fluorescein tear film break-up time (F-BUT), corneal fluorescein staining (CFS), Schirmer I test (SIT) and demodex folliculorum counting...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675342/surgical-treatment-of-unilateral-severe-simple-congenital-ptosis
#7
REVIEW
Ju-Hyang Lee, Yoon-Duck Kim
Unilateral congenital ptosis with poor levator function of ≤4 mm continues to be a difficult challenge for the oculoplastic surgeon. Surgical correction can be accomplished with unilateral frontalis suspension, maximal levator resection, or bilateral frontalis suspension with or without levator muscle excision of the normal eyelid. Bilateral frontalis suspension was proposed by Beard and Callahan to overcome the challenge of postoperative asymmetry, allowing symmetrical lagophthalmos on downgaze, postoperatively...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675288/systematic-evaluation-of-chromatographic-parameters-for-isoquinoline-alkaloids-on-xb-c18-core-shell-column-using-different-mobile-phase-compositions
#8
Ireneusz Sowa, Sylwia Zielińska, Jan Sawicki, Anna Bogucka-Kocka, Michał Staniak, Ewa Bartusiak-Szcześniak, Maja Podolska-Fajks, Ryszard Kocjan, Magdalena Wójciak-Kosior
Chelidonium majus L. is a rich source of isoquinoline alkaloids with confirmed anti-inflammatory, choleretic, spasmolytic, antitumor, and antimicrobial activities. However, their chromatographic analysis is difficult because they may exist both in charged and uncharged forms and may result in the irregular peak shape and the decrease in chromatographic system efficacy. In the present work, the separation of main C. majus alkaloids was optimized using a new-generation XB-C18 endcapped core-shell column dedicated for analysis of alkaline compounds...
2018: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/29674416/altered-white-matter-microstructure-in-the-corpus-callosum-and-its-cerebral-interhemispheric-tracts-in-adolescent-idiopathic-scoliosis-diffusion-tensor-imaging-analysis
#9
C Xue, L Shi, S C N Hui, D Wang, T P Lam, C-B Ip, B K W Ng, J C Y Cheng, W C W Chu
BACKGROUND AND PURPOSE: Neural system was one of the important contributors to the etiopathogenesis of adolescent idiopathic scoliosis; additionally, the morphology of corpus callosum interconnecting both hemispheres of the brain was found to be altered morphologically. Our aim was to evaluate and compare the microstructural changes of the corpus callosum and its interhemispheric white matter fiber tracts interconnecting both cerebral hemispheres in patients with adolescent idiopathic scoliosis and matched controls using diffusion tensor imaging...
April 19, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29673567/electric-acoustic-forward-masking-in-cochlear-implant-users-with-ipsilateral-residual-hearing
#10
Marina Imsiecke, Benjamin Krüger, Andreas Büchner, Thomas Lenarz, Waldo Nogueira
In order to investigate the temporal mechanisms of the auditory system, psychophysical forward masking experiments were conducted in cochlear implant users who had preserved acoustic hearing in the ipsilateral ear. This unique electric-acoustic stimulation (EAS) population allowed the measurement of threshold recovery functions for acoustic or electric probes in the presence of electric or acoustic maskers, respectively. In the electric masking experiment, the forward masked threshold elevation of acoustic probes was measured as a function of the time interval after the offset of the electric masker, i...
April 9, 2018: Hearing Research
https://www.readbyqxmd.com/read/29673166/revisiting-strephosymbolie-the-connection-between-interhemispheric-transfer-and-developmental-dyslexia
#11
Roberta Daini, Paola De Fabritiis, Chiara Ginocchio, Carlo Lenti, Cristina Michela Lentini, Donatella Marzorati, Maria Luisa Lorusso
The hypothesis that an atypical hemispheric specialization is associated to developmental dyslexia (DD) is receiving renewed interest, lending some support to Orton’s theory. In this article, we investigated whether interhemispheric transfer processes (IHT) are likely to be involved in developmental dyslexia. In this study, we tested 13 children with developmental dyslexia and 13 matched controls (aged 8 to 13 years) in four different tasks. In a tactile transfer task, the dyslexic children’s performance was less accurate...
April 17, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29672932/investigation-of-knee-control-as-a-lower-extremity-injury-risk-factor-a-prospective-study-in-youth-football
#12
Anu M Räisänen, Hillevi Arkkila, Tommi Vasankari, Kathrin Steffen, Jari Parkkari, Pekka Kannus, Hannele Forsman, Kati Pasanen
This prospective study in youth football examined the relationship between frontal plane knee projection angle (FPKPA) during the single-leg squat and sustaining an acute lower extremity injury or acute non-contact lower extremity injury. Secondly, side-to-side asymmetry in FPKPA and sex as injury risk factors were explored. In addition, we investigated the influence of age, sex and leg dominance on the FPKPA. A total of 558 youth football players (U11 to U14), participated in the single-leg squat test and prospective injury registration...
April 19, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29672904/growth-hormone-gh-insulin-like-growth-factor-1-igf-1-axis-hyperactivity-on-bone-fibrous-dysplasia-in-mccune-albright-syndrome
#13
Daniele Tessaris, Alison M Boyce, Margaret Zacharin, Patrizia Matarazzo, Roberto Lala, Luisa de Sanctis, Michael T Collins
CONTEXT: In fibrous dysplasia (BFD) normal bone and bone marrow are replaced by fibro-osseous tissue, leading to fracture, deformity and pain. BFD may be isolated, or in association with cutaneous hyperpigmentation and/or hyperfunctioning endocrinopathies, termed McCune-Albright syndrome (MAS). GH hypersecretion has been described in 10-20% of MAS-BFD patients. Aim of the study is to determine the impact of GH-insulin like growth factor 1 (IGF1) axis hyperactivity on MAS-BFD morbidities and the efficacy of GH excess therapy...
April 19, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29672644/the-relative-age-effect-is-larger-in-italian-soccer-top-level-youth-categories-and-smaller-in-serie-a
#14
Paolo Riccardo Brustio, Corrado Lupo, Alexandru Nicolae Ungureanu, Riccardo Frati, Alberto Rainoldi, Gennaro Boccia
The relative age effect (RAE; i.e., an asymmetry in the birth distribution) is a bias observed in sport competitions that may favour relatively older athletes in talent identification. Therefore, the aim of this study was to investigate the presence of RAE in elite soccer players competing in the Italian championships, even considering the discriminations of younger and older Serie A players (in relation to the median age of the sample), and different positional roles (i.e., goalkeeper, defender, midfielder, forward) for each observed category...
2018: PloS One
https://www.readbyqxmd.com/read/29671735/how-tattoos-can-complement-breast-reconstruction
#15
Lisa Franczak
Tattooing offers expanded possibilities for creative expression for women who have undergone mastectomies and breast reconstruction surgeries. Tattoo techniques for areola restoration, such as repigmentation, do not address breast asymmetry or heavy scarring, but breast tattoos can embolden a woman's sexuality, self-confidence, and sense of body reclamation, as well as strengthen her postsurgical capacity for relating to her breasts and expressing her identity. There are many factors involved when a tattoo artist is asked to design an image for a patient...
April 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29671435/electro-wetting-of-a-nanoscale-water-droplet-on-a-polar-solid-surface-in-electric-fields
#16
Fenhong Song, Long Ma, Jing Fan, Qicheng Chen, Guangping Lei, Ben Q Li
Molecular dynamics simulations were applied to study the wetting properties of nanoscale droplets on a polar silica solid substrate subjected to constant and alternative electric fields with various field frequencies. Results show that the external applied electric fields have significant effects on the wetting of the nanoscale droplet on a polar solid substrate. The droplet spreads asymmetrically under the effect of the external applied field, and this asymmetry culminates to the maximum when the electric field equals to 0...
April 19, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29670972/ionic-structure-around-polarizable-metal-nanoparticles-in-aqueous-electrolytes
#17
Bendix Petersen, Rafael Roa, Joachim Dzubiella, Matej Kanduč
Metal nanoparticles are receiving increased scientific attention owing to their unique physical and chemical properties that make them suitable for a wide range of applications in diverse fields, such as electrochemistry, biochemistry, and nanomedicine. Their high metallic polarizability is a crucial determinant that defines their electrostatic character in various electrolyte solutions. Here, we introduce a continuum-based model of a metal nanoparticle with explicit polarizability in the presence of different kinds of electrolytes...
April 19, 2018: Soft Matter
https://www.readbyqxmd.com/read/29670717/the-importance-of-the-posterior-joint-space-for-functional-mandibular-movements-a-laboratory-cross-sectional-study
#18
Cláudia-da Costa Cordeiro, Daniel-Humberto Pozza, Tadachi Tamaki, Antônio-Sérgio Guimarães
Background: The search for the ideal, healthy and reproducible position of the condyles is of utmost importance for dental diagnosis and treatment. Thus, the objective of this laboratory cross-sectional study was to verify the relationship between the posterior joint space and the mandibular lateral movements. Material and Methods: Dental casts from 15 women and 15 men with normal mastication, 28 natural teeth and no history of temporomandibular disorders or pain, were fabricated and mounted on a fully adjustable articulator...
January 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29670573/gait-asymmetry-in-people-with-parkinson-s-disease-is-linked-to-reduced-integrity-of-callosal-sensorimotor-regions
#19
Brett W Fling, Carolin Curtze, Fay B Horak
Background: Individuals with Parkinson's disease (PD) often manifest significant temporal and spatial asymmetries of the lower extremities during gait, which significantly contribute to mobility impairments. While the neural mechanisms underlying mobility asymmetries within this population remain poorly understood, recent evidence points to altered microstructural integrity of white matter fiber tracts within the corpus callosum as potentially playing a substantial role. Objectives: The purpose of this study was to quantify spatial and temporal gait asymmetries as well as transcallosal microstructural integrity of white matter fiber tracts connecting the primary and secondary sensorimotor cortices in people with PD and age-matched control participants...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29670571/electromyographical-gait-characteristics-in-parkinson-s-disease-effects-of-combined-physical-therapy-and-rhythmic-auditory-stimulation
#20
Christopher A Bailey, Federica Corona, Mauro Murgia, Roberta Pili, Massimiliano Pau, Julie N Côté
Background: In persons with Parkinson's disease (PD), gait dysfunctions are often associated with abnormal neuromuscular function. Physical therapy combined with auditory stimulation has been recently shown to improve motor function and gait kinematic patterns; however, the underlying neuromuscular control patterns leading to this improvement have never been identified. Objectives: (1) Assess the relationships between motor dysfunction and lower limb muscle activity during gait in persons with PD; (2) Quantify the effects of physical therapy with rhythmic auditory stimulation (PT-RAS) on lower limb muscle activity during gait in persons with PD...
2018: Frontiers in Neurology
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