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https://www.readbyqxmd.com/read/28732352/cerebral-blood-flow-changes-in-remitted-early-and-late-onset-depression-patients
#1
Wenxiang Liao, Ze Wang, Xiangrong Zhang, Hao Shu, Zan Wang, Duan Liu, Zhijun Zhang
Abnormal cerebral blood flow (CBF) is reportedly associated with major depressive disorder (MDD). We have investigated CBF changes in early-onset depression (EOD) and late-onset depression (LOD), and their impact on cognitive function. Thirty-two remitted EOD patients, 32 remitted LOD patients, and 43 age-matched healthy controls were recruited, and the pulsed arterial spin labeling data were scanned under 3.0T MRI and processed through voxel-by-voxel statistical analysis. Compared to healthy controls, LOD patients had decreased normalized CBF in the bilateral precuneus, cuneus, right fronto-cingulate-striatal areas, and right temporal, occipital and parietal lobes, but increased normalized CBF in the left frontal and temporal cortices and the cingulate gyrus...
July 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28731756/stochastic-chaos-in-a-turbulent-swirling-flow
#2
D Faranda, Y Sato, B Saint-Michel, C Wiertel, V Padilla, B Dubrulle, F Daviaud
We report the experimental evidence of the existence of a random attractor in a fully developed turbulent swirling flow. By defining a global observable which tracks the asymmetry in the flux of angular momentum imparted to the flow, we can first reconstruct the associated turbulent attractor and then follow its route towards chaos. We further show that the experimental attractor can be modeled by stochastic Duffing equations, that match the quantitative properties of the experimental flow, namely, the number of quasistationary states and transition rates among them, the effective dimensions, and the continuity of the first Lyapunov exponents...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731753/new-measurements-of-the-beam-normal-spin-asymmetries-at-large-backward-angles-with-hydrogen-and-deuterium-targets
#3
D Balaguer Ríos, K Aulenbacher, S Baunack, J Diefenbach, B Gläser, D von Harrach, Y Imai, E-M Kabuß, R Kothe, J H Lee, H Merkel, M C Mora Espí, U Müller, E Schilling, C Weinrich, L Capozza, F E Maas, J Arvieux, M A El-Yakoubi, R Frascaria, R Kunne, M Morlet, S Ong, J van de Wiele, S Kowalski, Y Prok
New measurements of the beam normal single spin asymmetry in the electron elastic and quasielastic scattering on the proton and deuteron, respectively, at large backward angles and at ⟨Q^{2}⟩=0.22  (GeV/c)^{2} and ⟨Q^{2}⟩=0.35  ( GeV/c)^{2} are reported. The experimentally observed asymmetries are compared with the theoretical calculation of Pasquini and Vanderhaeghen [Phys. Rev. C 70, 045206 (2004).PRVCAN0556-281310.1103/PhysRevC.70.045206]. The agreement of the measurements with the theoretical calculations shows a dominance of the inelastic intermediate excited states of the nucleon, πN and the Δ resonance...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731569/diversity-in-thermal-affinity-among-key-piscivores-buffers-impacts-of-ocean-warming-on-predator-prey-interactions
#4
Rebecca L Selden, Ryan D Batt, Vincent S Saba, Malin L Pinsky
Asymmetries in responses to climate change have the potential to alter important predator-prey interactions, in part by altering the location and size of spatial refugia for prey. We evaluated the effect of ocean warming on interactions between four important piscivores and four of their prey in the U.S. Northeast Shelf by examining species overlap under historical conditions (1968-2014) and with a doubling in CO2 . Because both predator and prey shift their distributions in response to changing ocean conditions, the net impact of warming or cooling on predator-prey interactions was not determined a priori from the range extent of either predator or prey alone...
July 21, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28731076/simple-gd-3-neu5nac-complexation-results-in-nmr-chemical-shift-asymmetries-of-structurally-equivalent-complex-type-n-glycan-branches
#5
Konstantin Usachev, Yoshiki Yamaguchi, Masayuki Takamatsu, Nataliya Pavlova, Vladimir Klochkov, Almira Kurbangalieva, Takefumi Murase, Taiji Shimoda, Katsunori Tanaka
In the present Communication, we propose a quite simple but previously overlooked approach for conveniently analyzing, assigning, and extracting sialic acid-containing N-glycan structures using high-resolution NMR spectroscopy without pre-installing metal chelators. Paramagnetic metals, such as Gd(3+), appear to bind to the carboxyl groups of N-acetylneuraminic acid when introduced at room temperature, leading to the measurement of nonequivalent proton and carbon NMR spectral signals among otherwise "identical" glycan branched structures...
July 21, 2017: Analyst
https://www.readbyqxmd.com/read/28730658/ferroelectrics-as-smart-mechanical-materials
#6
Kumara Cordero-Edwards, Neus Domingo, Amir Abdollahi, Jordi Sort, Gustau Catalan
The mechanical properties of materials are insensitive to space inversion, even when they are crystallographically asymmetric. In practice, this means that turning a piezoelectric crystal upside down or switching the polarization of a ferroelectric should not change its mechanical response. Strain gradients, however, introduce an additional source of asymmetry that has mechanical consequences. Using nanoindentation and contact-resonance force microscopy, this study demonstrates that the mechanical response to indentation of a uniaxial ferroelectric (LiNbO3 ) does change when its polarity is switched, and use this mechanical asymmetry both to quantify its flexoelectricity and to mechanically read the sign of its ferroelectric domains...
July 21, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28730501/the-pseudo-sah-sign-an-imaging-pitfall-in-postmortem-computed-tomography
#7
Go Shirota, Wataru Gonoi, Masako Ikemura, Masanori Ishida, Yukako Shintani, Hiroyuki Abe, Masashi Fukayama, Tomohiko Higashida, Hidemi Okuma, Osamu Abe
Postmortem computed tomography (PMCT) of the brain has an important role in detection of subarachnoid hemorrhage (SAH), which has a high mortality rate. However, a phenomenon known as "pseudo-SAH," or high-attenuation areas along the cisterns mimicking SAH, may be seen on CT. The aim of this study was to evaluate the diagnostic accuracy of brain PMCT for SAH and to identify the characteristics of pseudo-SAH. Findings on PMCT (sulcal effacement, asymmetry, maximum thickness of SAH signs, presence of acute/subacute intraventricular/intraparenchymal hemorrhage) and clinical history (left ventricular assist device [LVAD] implantation, anticoagulation therapy/coagulation disorder, global ischemia) were compared between subjects with true SAH and those with pseudo-SAH...
July 20, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28730339/breast-cancer-neoplastic-seeding-in-the-setting-of-image-guided-needle-biopsies-of-the-breast
#8
REVIEW
Lumarie Santiago, Beatriz E Adrada, Monica L Huang, Wei Wei, Rosalind P Candelaria
PURPOSE: To identify clinicopathologic, technical, and imaging features associated with neoplastic seeding (NS) following image-guided needle breast biopsy. METHODS: We performed an institutional review board-approved retrospective review of patients presenting with a new diagnosis of breast cancer or suspicious breast findings requiring biopsy with subsequent diagnosis of NS. The time from biopsy to NS diagnosis was calculated. Histology, grade, estrogen receptor (ER) status, progesterone receptor (PR) status, HER2 status, T category, and N category were recorded...
July 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28729848/the-functional-genetics-of-handedness-and-language-lateralization-insights-from-gene-ontology-pathway-and-disease-association-analyses
#9
Judith Schmitz, Stephanie Lor, Rena Klose, Onur Güntürkün, Sebastian Ocklenburg
Handedness and language lateralization are partially determined by genetic influences. It has been estimated that at least 40 (and potentially more) possibly interacting genes may influence the ontogenesis of hemispheric asymmetries. Recently, it has been suggested that analyzing the genetics of hemispheric asymmetries on the level of gene ontology sets, rather than at the level of individual genes, might be more informative for understanding the underlying functional cascades. Here, we performed gene ontology, pathway and disease association analyses on genes that have previously been associated with handedness and language lateralization...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28729847/effects-of-intensive-crew-training-on-individual-and-collective-characteristics-of-oar-movement-in-rowing-as-a-coxless-pair
#10
Mathieu Feigean, Mehdi R'Kiouak, Reinoud J Bootsma, Jérôme Bourbousson
This case study examined how two rowers adapted their rowing patterns following crew training as a newly formed coxless pair. The two participants were expert (double-oar) single scull-boat rowers. Performing as a crew in the coxless-pair's sweep-boat, where each rower operates a single oar, on-the-water data were collected before and after a 6-week intensive team-training program. Rowing patterns were characterized by the horizontal oar angle, oar angular velocity and linear oar-water velocity profiles during the catch (minimal oar angle) to finish (maximal oar angle) half-cycles of the propulsive water phase...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28727564/causal-inference-on-multidimensional-data-using-free-probability-theory
#11
Furui Liu, Lai-Wan Chan
In this paper, we deal with the problem of inferring causal relations for multidimensional data. Based on the postulate that the distribution of the cause and the conditional distribution of the effect given cause are generated independently, we show that the covariance matrix of the mean embedding of the cause in reproducing kernel Hilbert space (RKHS) is free independent with the covariance matrix of the conditional embedding of the effect given cause. This, called freeness condition, induces a cause-effect asymmetry that a designed measurement is $0$ in the causal direction but smaller than $0$ in the anticausal direction, and it uncovers the causal direction...
July 18, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28727556/effective-screening-and-classification-of-cervical-precancer-biopsy-imagery
#12
Jaidip Jagtap, Nishigandha Patil, Abdul K Parchur, Chayanika Pantola, Asha Agarwal, Kiran Pandey, Asima Pradhan
Microscope images of biopsy samples of cervical precancers conventionally discriminated by histopathology, the current "gold standard" for cancer detection, showed that their correlation properties are segregated into different classes. The correlation domains clearly indicate increasing cellular clustering in different grades of precancer compared to their normal counterparts. This trend indicates the probability of pixel distribution of the corresponding tissue images. Because the cell density is not uniform in the higher grades, the skewness (asymmetry of a distribution), kurtosis (sharpness of a distribution), entropy (randomness), and standard deviation are affected...
July 18, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28726117/applying-a-new-bilateral-mammographic-density-segmentation-method-to-improve-accuracy-of-breast-cancer-risk-prediction
#13
Shiju Yan, Yunzhi Wang, Faranak Aghaei, Yuchen Qiu, Bin Zheng
PURPOSE: How to optimally detect bilateral mammographic asymmetry and improve risk prediction accuracy remains a difficult and unsolved issue. Our aim was to find an effective mammographic density segmentation method to improve accuracy of breast cancer risk prediction. METHODS: A dataset including 168 negative mammography screening cases was used. We applied a mutual threshold to bilateral mammograms of left and right breasts to segment the dense breast regions...
July 19, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28725930/infant-positioning-baby-gear-use-and-cranial-asymmetry
#14
Anne H Zachry, Vikki G Nolan, Sarah B Hand, Susan A Klemm
Objectives This study aimed to identify predictors of cranial asymmetry. We hypothesize that among infants diagnosed with cranial asymmetry in the sampled region, there is an association between exposure to more time in baby gear and less awake time in prone and side-lying than in infants who do not present with this condition. Methods The study employed a cross sectional survey of caregivers of typically developing infants and infants diagnosed with cranial asymmetry. Results A mutivariable model reveals that caregivers of children who are diagnosed with cranial asymmetry report their children spending significantly less time in prone play than those children without a diagnosis of cranial asymmetry...
July 19, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28725189/inversion-reveals-perceptual-asymmetries-in-the-configural-processing-of-human-body
#15
Daniele Marzoli, Chiara Lucafò, Caterina Padulo, Giulia Prete, Laura Giacinto, Luca Tommasi
Ambiguous human bodies performing unimanual/unipedal actions are perceived more frequently as right-handed/footed rather than left-handed/footed, which suggests a perceptual and attentional bias toward the right side of others' body. A bias toward the right arm of human bodies could be adaptive in social life, most social interactions occurring with right-handed individuals, and the implicit knowledge that the dominant hand of humans is usually placed on their right side might also be included in body configural information...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28723996/bioethical-dimensions-of-international-cooperation-for-health-still-a-controversial-issue
#16
José Paranaguá de Santana
This essay stresses the importance of undertaking a critical analysis of international cooperation for health based upon reflections on diplomacy, acknowledging the ethical limits and possibilities of cooperation within this context. It emphasizes the importance of adopting an historical perspective, highlighting the circumstances surrounding the consolidation of the current international system, whereby, after two world wars, the victorious countries created the United Nations Organization, which today brings together all the world's nations, notwithstanding the fact that the majority of countries are in favor of significant changes to its institutional framework...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723994/structural-cooperation-the-fiocruz-experience
#17
José Roberto Ferreira, Luiz Eduardo Fonseca
This article examines the structural approach to health cooperation, focusing on its meaning as a method for promoting institutional policies to improve management models. We draw attention to the differences between this approach and the traditional disease-based approach, showing that the structural approach is centered on health systems, reinforces global governance, and embodies the Sustainable Development Goals (SDG), thus taking on a multi-sectoral dimension. This approach leverages the maximum potential of international cooperation by establishing structuring networks and promoting relations between partner countries through their national health institutions, schools of public health, and technical staff...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723781/assessment-of-optic-disc-and-ganglion-cell-layer-in-diabetes-mellitus-type-2
#18
Evre Pekel, Gökhan Tufaner, Hüseyin Kaya, Alper Kaşıkçı, Gökhan Deda, Gökhan Pekel
The purpose of this study was to compare the optic disc parameters, retinal nerve fiber (RNFL), and macular ganglion cell layers between patients with diabetes mellitus (DM) type 2 and healthy controls.In this cross-sectional study, 69 eyes of 69 diabetic patients without diabetic retinopathy and 47 eyes of 47 healthy controls were included. Optic disc parameters (i.e., rim area, disc area, cup to disc ratio, cup volume), RNFL, and macular ganglion cell-inner plexiform layers (GCL + IPL) thickness were measured by means of spectral domain optical coherence tomography...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28723733/hering-s-law-in-congenital-ptosis-evaluation-of-the-contralateral-response-to-unilateral-congenital-ptosis-repair
#19
Thomas J E Clark, Wesley J Klejch, Kai Wang, Richard C Allen, Jeffrey A Nerad, Keith D Carter, Erin M Shriver
PURPOSE: To determine the applicability and clinical relevance of Hering's law for the eyelids in cases of congenital ptosis. METHODS: A retrospective chart review and digital photograph analysis of patients who underwent unilateral congenital ptosis repair at a tertiary, university-based, Oculoplastics clinic was conducted. Pre- and postoperative eyelid height (marginal reflex distance), upper eyelid symmetry, and brow position were determined using ImageJ analysis software...
July 18, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28723655/long-non-coding-rna-tug1-as-a-potential-prognostic-biomarker-in-human-cancers-a-meta-analysis
#20
Peng-Ju Ma, Qing-Kai Guan, Lei Meng, Nan Qin, Jia Zhao, Bao-Zhe Jin
LncRNA taurine upregulated gene 1 (TUG1) is reportedly dysregulated in various cancers. We performed this meta-analysis to clarify the usefulness of TUG1 as a prognostic marker in malignant tumors. The PubMed, Medline, OVID, Cochrane Library, and Web of Science databases were searched from inception to Jan 11, 2017. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated to explore the relationship between TUG1 expression and overall survival (OS). Odds ratios (ORs) were calculated to assess the association between TUG1 expression and pathological parameters...
July 8, 2017: Oncotarget
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