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Introspection

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https://www.readbyqxmd.com/read/28508325/preliminary-results-of-a-novel-algorithmic-method-aiming-to-support-initial-causality-assessment-of-routine-pharmacovigilance-case-reports-for-medication-induced-liver-injury-the-pv-rucam
#1
Erik Scalfaro, Henk Johan Streefkerk, Michael Merz, Christoph Meier, David Lewis
INTRODUCTION: Data incompleteness in pharmacovigilance (PV) health records limits the use of current causality assessment methods for drug-induced liver injury (DILI). In addition to the inherent complexity of this adverse event, identifying cases of high causal probability is difficult. OBJECTIVE: The aim was to evaluate the performance of an improved, algorithmic and standardised method called the Pharmacovigilance-Roussel Uclaf Causality Assessment Method (PV-RUCAM), to support assessment of suspected DILI...
May 15, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28504525/introspection-of-subjective-feelings-is-sensitive-and-specific
#2
Laurence Questienne, Jean-Philippe van Dijck, Wim Gevers
Conversely to behaviorist ideas, recent studies suggest that introspection can be accurate and reliable. However, an unresolved question is whether people are able to report specific aspects of their phenomenal experience, or whether they report more general nonspecific experiences. To address this question, we investigated the sensitivity and validity of our introspection for different types of conflict. Taking advantage of the congruency sequence effect, we dissociated response conflict while keeping visual conflict unchanged in a Stroop and in a priming task...
May 15, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28504334/advances-in-functional-brain-imaging-technology-and-developmental-neuro-psychology-their-applications-in-the-jungian-analytic-domain
#3
Leon Petchkovsky
Analytical psychology shares with many other psychotherapies the important task of repairing the consequences of developmental trauma. The majority of analytic patients come from compromised early developmental backgrounds: they may have experienced neglect, abuse, or failures of empathic resonance from their carers. Functional brain imagery techniques including Quantitative Electroencephalogram (QEEG), and functional Magnetic Resonance Imagery (fMRI), allow us to track mental processes in ways beyond verbal reportage and introspection...
June 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28461740/pharmacokinetic-interactions-between-glimepiride-and-rosuvastatin-in-healthy-korean-subjects-does-the-slco1b1-or-cyp2c9-genetic-polymorphism-affect-these-drug-interactions-observations-and-introspection-of-the-bioanalysis
#4
https://www.readbyqxmd.com/read/28425736/implicit-approach-and-avoidance-in-patients-with-obsessive-compulsive-disorder
#5
Barbara Cludius, Anne Katrin Külz, Sarah Landmann, Steffen Moritz, Charlotte E Wittekind
Avoidance is regarded as an important feature for the development and maintenance of obsessive-compulsive disorder (OCD) and is usually assessed using explicit measures such as self-report scales. However, some behavioral schemata are unavailable to introspection, making them partially inaccessible by explicit measures. We used an approach-avoidance task (AAT) as an implicit measure to examine behavioral tendencies in patients with OCD, including patients with checking- and contamination-related symptoms (n = 63), compared with a healthy control group (n = 30)...
April 20, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28406348/motivations-for-using-mdma-ecstasy-molly-among-african-americans-implications-for-prevention-and-harm-reduction-programs
#6
Khary K Rigg
Despite the growing popularity of MDMA (ecstasy/molly) among African Americans, their motives for using the drug are still largely unknown. The purpose of this study was to identify and describe the most salient motivations for using MDMA among this understudied population. In-depth interviews (n = 15) were conducted with a sample of African American young adults in Southwest Florida between August 2014 and November 2015. The primary motivations for using MDMA included: (1) altering the effects of marijuana and alcohol; (2) lasting longer sexually; (3) enhancing sexual pleasure; and (4) facilitating "freaky" sexual experiences...
April 13, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28387587/multiple-object-tracking-as-a-tool-for-parametrically-modulating-memory-reactivation
#7
Jordan Poppenk, Ken A Norman
Converging evidence supports the "nonmonotonic plasticity" hypothesis that, although complete retrieval may strengthen memories, partial retrieval weakens them. Yet, the classic experimental paradigms used to study effects of partial retrieval are not ideally suited to doing so, because they lack the parametric control needed to ensure that the memory is activated to the appropriate degree (i.e., that there is some retrieval but not enough to cause memory strengthening). Here, we present a novel procedure designed to accommodate this need...
April 7, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28374336/therapeutic-potential-and-utility-of-elacridar-with-respect-to-p-glycoprotein-inhibition-an-insight-from-the-published-in-vitro-preclinical-and-clinical-studies
#8
Ranjeet Prasad Dash, R Jayachandra Babu, Nuggehally R Srinivas
The occurrence of efflux mechanisms via Permeability-glycoprotein (P-gp) recognized as an important physiological process impedes drug entry or transport across membranes into tissues. In some instances, either low oral bioavailability or lack of brain penetration has been attributed to P-gp mediated efflux activity. Therefore, the objective of development of P-gp inhibitors was to facilitate the attainment of higher drug exposures in tissues. Many third-generation P-gp inhibitors such as elacridar, tariquidar, zosuquidar, etc...
April 3, 2017: European Journal of Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/28356722/from-therapeutic-patient-education-principles-to-educative-attitude-the-perceptions-of-health-care-professionals-a-pragmatic-approach-for-defining-competencies-and-resources
#9
Benoit Pétré, Remi Gagnayre, Vincent De Andrade, Olivier Ziegler, Michèle Guillaume
Educative attitude is an essential, if implicit, aspect of training to acquire competency in therapeutic patient education (TPE). With multiple (or nonexistent) definitions in the literature, however, the concept needs clarification. The primary aim of this study was to analyze the representations and transformations experienced by health care professionals in the course of TPE training in order to characterize educative attitude. We conducted an exploratory qualitative study using several narrative research-based tools with participants of two TPE continuing education courses...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28348983/future-of-profession
#10
EDITORIAL
Raman Kumar
Being a doctor in today's time is a tough experience in many parts of the world. Many young people motivated by the traditional image of profession and desire for service opted for this vocation without anticipating today's challenging environment. Bad press, violence against doctors, tough employment conditions, unemployment, and lack of societal respect have become common phenomenon across the world. It is indeed time to introspect. The institution of medical profession is rapidly transforming not necessarily only under the influence of rapidly changing technology...
October 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28341897/researcher-readiness-for-participating-in-community-engaged-dissemination-and-implementation-research-a-conceptual-framework-of-core-competencies
#11
Christopher M Shea, Tiffany L Young, Byron J Powell, Catherine Rohweder, Zoe K Enga, Jennifer E Scott, Lori Carter-Edwards, Giselle Corbie-Smith
Participating in community-engaged dissemination and implementation (CEDI) research is challenging for a variety of reasons. Currently, there is not specific guidance or a tool available for researchers to assess their readiness to conduct CEDI research. We propose a conceptual framework that identifies detailed competencies for researchers participating in CEDI and maps these competencies to domains. The framework is a necessary step toward developing a CEDI research readiness survey that measures a researcher's attitudes, willingness, and self-reported ability for acquiring the knowledge and performing the behaviors necessary for effective community engagement...
March 24, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28316205/-research-on-yi-yu-medical-education-a-professional-journal-on-medical-education-during-the-period-of-anti-japanese-war
#12
L P He
Founded in October, 1935, Yi yu (Medical Education) was the first professional journal of medical education in China. Unlike other medical journals, Yi yu had strong official background. It was sponsored by the Medical Education Committee of Ministry of Education of the National Government, whose chief editor, editors and authors were mostly authoritative scholars. Its publication time was 1935-1941, and was once an important basis reflecting the development levels and results of Chinese medicine during the Anti-Japanese War, introspecting Chinese medicine education, spreading medical knowledge...
January 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28280279/behavioural-phenotypes-and-the-structure-of-human-cognition
#13
Dana Bentzen-Bilkvist, Andrea Migliano, Lucio Vinicius
Human cognitive uniqueness is often defined in terms of cognitive abilities such as introspection, imitation and cooperativeness. However, little is known about how those traits vary in populations or correlate across individuals. Here we test whether those three cognitive domains are correlated manifestations of an underlying factor, analogous to the psychometric 'g' factor, or independent 'behavioural phenotypes', analogous to the 'Big-Five' personality components. We selected eight variables measuring introspection and extraversion, verbal and physical imitation, cooperation and punishment, and evaluated their individual variability, domain-consistency and sub-structuring in a sample of 84 individuals...
2017: Evolutionary Biology
https://www.readbyqxmd.com/read/28256458/fats-fatty-acids-in-indian-diets-time-for-serious-introspection
#14
REVIEW
Indu Mani, Anura V Kurpad
Recommended dietary allowances for fat and fatty acid (FA) intakes are set on global standards aimed at prevention of lifestyle diseases. Yet, the fat composition of a diet is both ethnic/region specific as well as income dependent. Indian diets are predominantly vegetarian and relatively low in fat. Furthermore, the main sources of fat are of plant origin rather than animal origin. This results in a diet that is relatively low in saturated FA, high in n-6 polyunsaturated fatty acids (PUFA), and very low in n-3 PUFA...
October 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28243158/an-assessment-of-meaning-in-life-threatening-illness-development-of-the-healing-experience-in-all-life-stressors-heals
#15
Danetta Hendricks Sloan, Karlynn BrintzenhofeSzoc, Tiffany Kichline, Karen Baker, Jean-Paul Pinzon, Christina Tafe, Lingsheng Li, M Jennifer Cheng, Ann Berger
CONTEXT: Patients with life-threatening or chronic illness report an experience of increased positive psychological, social, and/or spiritual change during diagnosis and/or treatment of their illness, even in the face of unfavorable prognosis. This transformation begins through the ability to make their life meaningful by forming meaningful connections that emerge through self-introspection and relationships with a divine entity, nature, and other people. The Healing Experience in All Life Stressors (HEALS) assessment provides a way to identify distress-causing changes that may interfere with the development of meaning and psycho-social-spiritual homeostasis...
2017: Patient related Outcome Measures
https://www.readbyqxmd.com/read/28222380/libet-s-experiment-questioning-the-validity-of-measuring-the-urge-to-move
#16
Tomáš Dominik, Daniel Dostál, Martin Zielina, Jan Šmahaj, Zuzana Sedláčková, Roman Procházka
The time of subjectively registered urge to move (W) constituted the central point of most Libet-style experiments. It is therefore crucial to verify the W validity. Our experiment was based on the assumption that the W time is inferred, rather than introspectively perceived. We used the rotating spot method to gather the W reports together with the reports of the subjective timing of actual movement (M). The subjects were assigned the tasks in two different orders. When measured as first in the respective session, no significant difference between W and M values was found, which suggests that uninformed subjects tend to confuse W for M reports...
March 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28220146/horseback-riding-improves-the-ability-to-cause-the-appropriate-action-go-reaction-and-the-appropriate-self-control-no-go-reaction-in-children
#17
Nobuyo Ohtani, Kenji Kitagawa, Kinuyo Mikami, Kasumi Kitawaki, Junko Akiyama, Maho Fuchikami, Hidehiko Uchiyama, Mitsuaki Ohta
BACKGROUND: There are many obvious health benefits to riding, including developing a strong core and legs, but there are also many less obvious benefits, such as increased confidence and introspection. Few studies have addressed the effects of horseback riding on children and the mechanisms underlying how riding affects humans. We examined the effects of horseback riding on the ability to distinguish Go/No-go tasks and solve arithmetic problems in children. METHODS: The subjects were 34 boys and 72 girls, aged 10-12 years old, which were divided into three groups (horse riding, walking, and resting)...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28216746/whither-orthopaedics-today-an-introspection
#18
Rakesh Bhargava
No abstract text is available yet for this article.
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28208890/operational-assessment-of-icds-scheme-at-grass-root-level-in-a-rural-area-of-eastern-india-time-to-introspect
#19
Jyotiranjan Sahoo, Preetam B Mahajan, Sourabh Paul, Vikas Bhatia, Abhinash K Patra, Dilip Kumar Hembram
INTRODUCTION: Integrated Child Development Service (ICDS), a flagship program of Government of India (GoI) for early childhood development hasn't delivered the desired results since its inception four decades ago. This could be due to infrastructural problems, lack of awareness and proper utilization by the local people, inadequate program monitoring and corruption in food supplies, etc. This study is an audit of 36 Anganwadi centres at Khordha district, Odisha, to evaluate the implementation of the ICDS...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28196093/a-massive-experiment-on-choice-blindness-in-political-decisions-confidence-confabulation-and-unconscious-detection-of-self-deception
#20
Andrés Rieznik, Lorena Moscovich, Alan Frieiro, Julieta Figini, Rodrigo Catalano, Juan Manuel Garrido, Facundo Álvarez Heduan, Mariano Sigman, Pablo A Gonzalez
We implemented a Choice Blindness Paradigm containing political statements in Argentina to reveal the existence of categorical ranges of introspective reports, identified by confidence and agreement levels, separating easy from very hard to manipulate decisions. CBP was implemented in both live and web-based forms. Importantly, and contrary to what was observed in Sweden, we did not observe changes in voting intentions. Also, confidence levels in the manipulated replies where significantly lower than in non-manipulated cases even in undetected manipulations...
2017: PloS One
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