Pedro E P Carvalho, Douglas M Gewehr, Isabele A Miyawaki, Alleh Nogueira, Nicole Felix, Philippe Garot, Arthur Darmon, Patrizio Mazzone, Alberto Preda, Bruno R Nascimento, Luiz F Kubrusly, Rhanderson Cardoso
BACKGROUND: The optimal antithrombotic therapy following left atrial appendage occlusion (LAAO) in patients with nonvalvular atrial fibrillation (AF) remains uncertain. OBJECTIVES: In this study, the authors sought to compare the efficacy and safety of various antithrombotic strategies after LAAO. METHODS: We searched the Medline, Cochrane, EMBASE, LILACS, and ClinicalTrials.gov databases for studies reporting outcomes after LAAO, stratified by antithrombotic therapy prescribed at postprocedural discharge...
October 31, 2023: Journal of the American College of Cardiology