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https://www.readbyqxmd.com/read/28822197/-systematic-review-of-kudiezi-injection-drug-safety
#1
Shan-Shan Gao, Rui-Zhao Cui, Yan-Ming Xie, Xing Liao, Xiao-Yan Gao, Ji-Dong Wang
To systematically evaluate the safety of Kudiezi injection. Databases such as Cochrane library, Medline, EMbase, Web of Science, Clinical Trials, CBM, CNKI, VIP, Wanfang and Chinese Clinical Trial Register were searched to collect the literature on all the study types of Kudiezi injection. Two researchers screened literature, assessed quality and extracted data according to inclusion and exclusion criteria. All studies were assessed by using internationally recognized methodological quality assessment tools or reporting quality evaluation criteria; Meta-analysis of adverse drug reaction/adverse events (ADR/AE) of Kudiezi injection was performed by using Stata 12...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28820664/association-of-socioeconomic-status-with-consumption-of-cigarettes-illicit-drugs-and-alcohol
#2
Maryam Marzban, Maryam Hadji, Mahin Gholipour, Hamideh Rashidian, Abbas Rezaianzadeh, Jafar Hasanzadeh, Ali Akbar Haghdoost, Afarin Rahimi-Movaghar, Reza Ghiasvand, Abdolvahab Moradi, Hossein Khavari-Daneshvar, Elisabete Weiderpass, Farin Kamangar, Kazem Zendehdel
INTRODUCTION AND AIMS: Socioeconomic Status (SES) is considered as one of the important factors associated with use of various drugs. The present study aimed to investigate the effect of SES on cigarette smoking, alcohol use, drug use, and passive exposure to opium and cigarette smoke. DESIGN AND METHODS: In this study, which is part of a multicenter case-control study, the research hypothesis was checked among controls who had referred to hospitals. Data were collected through a questionnaire and laboratory tests to determine the actual consumers of opium and other illicit drugs...
August 18, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28819377/effect-of-pomalidomide-on-relapsed-refractory-multiple-myeloma-a-systematic-review-and-meta-analysis
#3
Runzhe Chen, Yujie Wang, Chengxin Luan, Chong Gao, Xiaoping Zhang, Baoan Chen
In this work, we aim to further analyze the effect of pomalidomide for relapsed and/or refractory multiple myeloma (RRMM). A systematic literature search of PubMed, MEDLINE and EMBASE was conducted on September 20, 2016. Pooled effect size (ES) with corresponding 95% confidence intervals (CIs) were calculated using random-effects model. STATA software (version 12.0; Stata Corporation; College Station, TX, USA) was employed to do all statistical analyses. A total of 8 studies were included for analysis. The combined results demonstrated that the pooled proportion of overall response rate (ORR) was 0...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28814320/intrathecal-morphine-versus-femoral-nerve-block-for-pain-control-after-total-knee-arthroplasty-a-meta-analysis
#4
Yi Tang, Xu Tang, Qinghua Wei, Hui Zhang
BACKGROUND: This meta-analysis aims to illustrate the efficacy and safety of intrathecal morphine (ITM) versus femoral nerve block (FNB) for pain control after total knee arthroplasty (TKA). METHODS: In April 2017, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, Cochrane Database of Systematic Reviews, Cami Info. Inc., Casalini databases, EBSCO databases, Verlag database and Google database. Data on patients prepared for TKA surgery in studies that compared ITM versus FNB for pain control after TKA were collected...
August 16, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28810978/factors-associated-with-medical-school-entrants-interest-in-military-financial-assistance-in-exchange-for-a-service-obligation-the-michigan-state-university-college-of-human-medicine-cohort
#5
Dean G Sienko, Kathleen Oberst
INTRODUCTION: The U.S. military offers comprehensive scholarships to medical students to help offset costs in exchange for either reserve or active duty service commitments. Our goal was to describe to what degree newly admitted students to Michigan State University's College of Human Medicine were aware of and interested in these opportunities. MATERIALS AND METHODS: We surveyed 176 newly admitted students at the beginning and immediately following a presentation on military medicine opportunities...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28803602/short-and-long-term-therapeutic-efficacies-of-intravenous-transplantation-of-bone-marrow-stem-cells-on-cardiac-function-in-rats-with-acute-myocardial-infarction-a-meta-analysis-of-randomized-controlled-trials
#6
Can Jiang, Dong Zheng, Yun-Lu Feng, Jun Guo, Hai-Rui Li, Ai-Dong Zhang
Objective To investigate the short- and long-term therapeutic efficacies of intravenous trans- plantation of bone marrow stem cells (MSCs) in rats with experimental myocardial infarction by meta- analysis. Methods Randomized controlled trials were systematically searched from PubMed, Science Citation Index (SCI), Chinese journal full-text database (CJFD) up to December 2014. While the experimental groups (MSCs groups) were injected MSCs intravenously, the control groups were injected Delubecco's minimum essential medium (DMEM) or phosphate buffered saline (PBS)...
September 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28800602/mefv-m694v-mutation-has-a-role-in-susceptibility-to-ankylosing-spondylitis-a-meta-analysis
#7
Linqing Zhong, Hongmei Song, Wei Wang, Ji Li, Mingsheng Ma
OBJECTIVE: The aim of the current study was to determine the contributions of several common mutations in the Mediterranean fever (MEFV) gene, namely, E148Q, M680I, M694V and V726A, to ankylosing spondylitis (AS) susceptibility. METHODS: Two investigators independently searched the literature regarding the association of MEFV with AS in the PubMed, EMBASE, Web of Science, and Scopus databases. They independently selected eligible articles and then extracted data from the included studies...
2017: PloS One
https://www.readbyqxmd.com/read/28797919/the-efficacy-and-safety-of-using-a-bipolar-sealer-to-prevent-blood-loss-in-spine-surgery-a-meta-analysis
#8
REVIEW
Di Lu, Wei-Guo Ding, Hong-Feng Sheng, Xin-Wei Xu, Ying-Xiao Zhang, Weixing Xu
OBJECTIVE: The purpose of this systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to evaluate the effect of using a bipolar sealer to prevent surgical bleeding in spine surgery. METHODS: In June 2017, the PubMed, Embase, Cochrane controlled trials register, Web of Science, Google, and Chinese Wanfang databases were used to identify RCTs and non-RCTs comparing the effects of intraoperative placement of a bipolar sealer versus standard electrocautery with regard to blood loss and blood transfusion...
August 7, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28797918/oral-tranexamic-acid-can-reduce-blood-loss-after-total-knee-and-hip-arthroplasty-a-meta-analysis
#9
REVIEW
Guang-Lei Li, Yong-Mei Li
OBJECTIVE: The aim of the present study was to compare the efficacy and safety of oral tranexamic acid (TXA) with controls or intravenous TXA in patients undergoing total joint arthroplasty (TJA) in a systematic review and meta-analysis. METHODS: We systematically searched randomized controlled trials (RCTs) from PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science and Google databases. Any studies comparing oral TXA versus a control group or intravenous TXA for patients prepared for TJA were included...
August 7, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28797296/intermittent-preventive-treatment-of-malaria-in-pregnancy-a-cross-sectional-survey-to-assess-uptake-of-the-new-sulfadoxine-pyrimethamine-five-dose-policy-in-ghana
#10
Ivy Owusu-Boateng, Francis Anto
BACKGROUND: Malaria in pregnancy poses a great risk to both mother and fetus. In Ghana, malaria accounts for 3.4% of deaths and 16.8% of all hospital admissions in pregnant women. In 2014, Ghana updated her policy on intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) to reflect the updated policy of the WHO. This study determined the level of uptake of sulfadoxine pyrimethamine (SP) to serve as baseline for monitoring progress and also reviewed stock levels of SP, a key factor in the programme implementation...
August 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28797275/sero-prevalence-of-hepatitis-b-infection-among-blood-donors-in-a-secondary-care-hospital-ghana-2014-a-retrospective-analysis
#11
Eric Osei, Sylvester Yao Lokpo, Eric Agboli
BACKGROUND: The prevalence of transfusion associated hepatitis B virus infection varies across different geographical populations. Establishing the sero-prevalence of the disease is important to informing the direction of preventive and control strategies. We sought to estimate the sero-prevalence of hepatitis B surface antigen among blood donors in Ho Municipal Hospital, Ghana. METHODS: This was a retrospective study which involved reviewing of blood donation records for the year 2014 in Ho Municipal Hospital...
August 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28797050/correlation-between-p-stat3-overexpression-and-prognosis-in-lung-cancer-a-systematic-review-and-meta-analysis
#12
Mengting Tong, Jing Wang, Nanyu Jiang, Hongming Pan, Da Li
OBJECTIVE: Previous studies have shown the correlation between p-STAT3 overexpression and prognosis in a variety of human tumors. However, their correlation in lung cancer remains controversial. We performed a systematic review and meta-analysis to explore the correlation between p-STAT3 overexpression and prognosis in lung cancer patients. METHODS: We searched PubMed, Embase, Web of Science, CNKI, VIP, and WanFang Data to identify relevant studies. Two reviewers independently screened the literature search results, extracted data, and assessed the methodological quality of the included studies...
2017: PloS One
https://www.readbyqxmd.com/read/28797030/one-step-nucleic-acid-amplification-assay-is-an-accurate-technique-for-sentinel-lymph-node-biopsy-of-breast-cancer-patients-a-meta-analysis
#13
Fang Shi, Qian Zhang, Zhenzhen Liang, Mengmeng Zhang, Xin Liu
BACKGROUND: To estimate the accuracy of one-step nucleic acid amplification (OSNA) assay as an intra-operative sentinel lymph node biopsy (SLNB) for sentinel lymph node (SLN) metastasis in breast cancer. METHODS: PubMed, Cochrane Library and Web of Science databases were searched by two independent reviewers to retrieve literature with per-patient analysis. The deadline was up until December 2016. A meta-analysis was performed using STATA, Meta-Disc, and Revman software...
August 10, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28795920/risk-factors-associated-with-neonatal-deaths-a-matched-case-control-study-in-indonesia
#14
Asnawi Abdullah, Krishna Hort, Yuli Butu, Louise Simpson
Background Similar to global trends, neonatal mortality has fallen only slightly in Indonesia over the period 1990-2010, with a high proportion of deaths in the first week of life. Objective This study aimed to identify risk factors associated with neonatal deaths of low and normal birthweight infants that were amenable to health service intervention at a community level in a relatively poor province of Indonesia. Design A matched case-control study of neonatal deaths reported from selected community health centres (puskesmas) was conducted over 10 months in 2013...
December 2016: Global Health Action
https://www.readbyqxmd.com/read/28795402/meta-analysis-of-the-association-between-dietary-inflammatory-index-dii-and-cancer-outcomes
#15
Mackenzie E Fowler, Tomi F Akinyemiju
Pro-inflammatory dietary patterns have been associated with increased cancer risk and mortality. We present a systematic review and meta-analysis of the current published literature on a Dietary Inflammatory Index (DII) score and its association with cancer risk and mortality outcomes. Published articles from online databases (PubMed, Scopus, and Embase) examining the association between DII and any cancer risk, incidence, or mortality between 1980 and November 2016 were selected for review. Results of studies meeting inclusion criteria were summarized and meta-analyzed using STATA to generate summary measures of association across studies...
August 10, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28793340/neonatal-infant-and-under-five-mortalities-in-nigeria-an-examination-of-trends-and-drivers-2003-2013
#16
Oyewale Mayowa Morakinyo, Adeniyi Francis Fagbamigbe
Neonatal (NMR), infant (IMR) and under-five (U5M) mortality rates remain high in Nigeria. Evidence-based knowledge of trends and drivers of child mortality will aid proper interventions needed to combat the menace. Therefore, this study assessed the trends and drivers of NMR, IMR, and U5M over a decade in Nigeria. A nationally representative data from three consecutive Nigeria Demographic and Household Surveys (NDHS) was used. A total of 66,158 live births within the five years preceding the 2003 (6029), 2008 (28647) and 2013 (31482) NDHS were included in the analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28793114/elderly-who-take-care-of-elderly-a-study-on-the-frailty-syndrome
#17
Ariene Angelini Dos Santos-Orlandi, Tábatta Renata Pereira de Brito, Ana Carolina Ottaviani, Estefani Serafim Rossetti, Marisa Silvana Zazzetta, Sofia Cristina Iost Pavarini
Objective: Identifying prevalence of frailty in elderly caregivers inserted in a high social vulnerability context and its correlation with sociodemographic and health aspects. Method: Descriptive, correlational and cross-sectional study. Forty elderly caregivers were evaluated with: questionnaire for caregiver characterization, Mini Mental State Examination, Katz Index, Lawton instrumental activities of daily living scale, Geriatric Depression Scale and the frailty phenotype proposed by Fried...
July 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28793005/the-diagnostic-value-of-narrow-band-imaging-for-early-and-invasive-lung-cancer-a-meta-analysis
#18
Juanjuan Zhu, Wei Li, Jihong Zhou, Yuqing Chen, Chenling Zhao, Ting Zhang, Wenjia Peng, Xiaojing Wang
This study aimed to compare the ability of narrow-band imaging to detect early and invasive lung cancer with that of conventional pathological analysis and white-light bronchoscopy. We searched the PubMed, EMBASE, Sinomed, and China National Knowledge Infrastructure databases for relevant studies. Meta-disc software was used to perform data analysis, meta-regression analysis, sensitivity analysis, and heterogeneity testing, and STATA software was used to determine if publication bias was present, as well as to calculate the relative risks for the sensitivity and specificity of narrow-band imaging vs those of white-light bronchoscopy for the detection of early and invasive lung cancer...
July 2017: Clinics
https://www.readbyqxmd.com/read/28791983/a-descriptive-study-of-the-morbidity-pattern-of-older-persons-presenting-at-a-geriatric-centre-in-southwestern-nigeria
#19
E O Cadmus, L A Adebusoye, O O Olowookere, O G Oluwatosin, E T Owoaje, T O Alonge
CONTEXT: Rapid population ageing is a demographic reality in most countries of the world. Old age is associated with changes which may culminate in health problems, necessitating provision of appropriate preventive, curative, and rehabilitative services. However, reports from many low- and middle-income countries have shown lack of preparedness to cater for the healthcare needs of older persons. AIM: This study described the morbidity profile and its determinants among persons aged 60 years and above who presented at an established geriatric centre in southwestern Nigeria...
July 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28790842/association-of-fhit-expression-and-fhit-gene-hypermethylation-with-liver-cancer-risk-a-prisma-compliant-meta-analysis
#20
Yaping Zhang, Xiao Xu, Zhiliang Chen, Zhenhua Zhao
BACKGROUND: There have been suggestions that fragile histidine triad protein (FHIT) expression and FHIT gene hypermethylation were crucial to the pathogenesis of liver cancer. However, the conclusions remained unclear because of small sample size, disease subtype, and different detection techniques. Therefore, we performed a meta-analysis to estimate the associations of FHIT expression and FHIT gene hypermethylation with liver cancer pathogenesis. METHODS: Studies that were published in electronic databases, such as PubMed, Web of Knowledge, China National Knowledge Infrastructure (CNKI), VIP, and WanFang, were retrieved and selected for the meta-analysis...
2017: OncoTargets and Therapy
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