keyword
https://read.qxmd.com/read/38547205/changes-in-the-intestinal-microbiota-of-individuals-with-non-alcoholic-fatty-liver-disease-based-on-sequencing-an-updated-systematic-review-and-meta-analysis
#1
JOURNAL ARTICLE
Wenpin Cai, Ting Qiu, Weitao Hu, Taiyong Fang
BACKGROUND: Alterations in the composition and abundance of the intestinal microbiota occur in non-alcoholic fatty liver disease (NAFLD). However, the results are inconsistent because of differences in the study design, subject area, and sequencing methodology. In this study, we compared the diversity and abundance of the intestinal microbiota of patients with NAFLD and healthy individuals through a systematic review and meta-analysis. METHODS: Three databases (PubMed, EMBASE, and Cochrane Library) were searched from their inception to March 20, 2023...
2024: PloS One
https://read.qxmd.com/read/38547179/suicidal-ideation-and-associated-factors-among-pregnant-women-attending-antenatal-care-at-public-hospitals-of-harari-regional-state-eastern-ethiopia-a-cross-sectional-study
#2
JOURNAL ARTICLE
Tilahun Bete, Tilahun Ali, Tadesse Misgana, Abraham Negash, Teklu Abraham, Dekeba Teshome, Addisu Sirtsu, Kabtamu Nigussie, Abdulkerim Amano
BACKGROUND: Suicide is a global issue. It is the third responsible for death among the reproductive age group. Pregnancy is a complicated event and crucial in the life of a woman with considerable physiological, hormonal changes, social, and mental changes. However, third-world countries like Ethiopia have not been investigated well. Therefore, the study planned to assess the magnitude and factors associated with suicidal ideation. Furthermore, it will identify the role of hyperemesis gravidarum on suicidal ideation...
2024: PloS One
https://read.qxmd.com/read/38546902/the-value-of-neutrophil-to-lymphocyte-ratio-in-predicting-severity-of-coronary-involvement-and-long-term-outcome-of-percutaneous-coronary-intervention-in-patients-with-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#3
REVIEW
Farzad Shahsanaei, Shahin Abbaszadeh, Soudabeh Behrooj, Nima Rahimi Petrudi, Bahareh Ramezani
BACKGROUND: The value of counting inflammatory cells and especially their counting ratio in predicting adverse clinical outcomes in patients with acute coronary syndrome (ACS) undergoing revascularization has been shown, but the results of studies have been very diverse and paradoxical. The aim of the current study was to systematically review the studies that investigated the role of increased neutrophil-to-lymphocyte ratio (NLR) in predicting long-term clinical outcomes in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI)...
March 28, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38545720/carnosine-histidine-containing-dipeptide-supplementation-improves-depression-and-quality-of-life-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
JOURNAL ARTICLE
Robel Hussen Kabthymer, Saeede Saadati, Mark Lee, Rohit Hariharan, Jack Feehan, Aya Mousa, Barbora de Courten
CONTEXT: Mental ill-health is a common and growing issue, affecting 1 in 8 individuals or 970 million people worldwide in 2019. Histidine-containing dipeptides (HCDs) have been suggested to mitigate some aspects of mental ill-health, but a quantitative synthesis of the evidence is lacking. Therefore, a systematic review and meta-analysis of randomized controlled trials was conducted. OBJECTIVE: To summarize the evidence on the effects of HCDs on mental health outcomes...
March 27, 2024: Nutrition Reviews
https://read.qxmd.com/read/38545554/effectiveness-and-safety-of-danshen-injections-in-treatment-of-cardiac-failure-a-network-meta-analysis
#5
REVIEW
Yuchen Song, Nan Song, Lianqun Jia, Yupeng Pei
Objective: The purpose of this network meta-analysis (NMA) was to compare the therapeutic effects of various Danshen ( Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma]) injections on heart failure to determine the optimal Danshen injection combined with conventional treatment. Methods: 8 databases were searched from the inception of these databases to May 2023 to collect randomized controlled trials (RCTs) on the effectiveness and safety of Danshen injections in the treatment of heart failure...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38545444/hematological-abnormalities-and-associated-factors-among-patients-with-hypothyroidism-at-the-university-of-gondar-comprehensive-specialized-hospital
#6
JOURNAL ARTICLE
Dereje Mengesha Berta, Yemataw Gelaw, Elias Shiferaw, Abateneh Melkamu, Gebrehiwot Lema Legese, Tiruneh Adane, Befikad Mandefro
OBJECTIVE: Abnormalities in blood cells are frequently associated with thyroid hormone disorders as a result of their involvement in the proliferation and production of blood cells. This study aimed to determine the magnitude and associated factors of hematological abnormalities in patients with hypothyroidism. METHODS: A cross-sectional study was conducted from January 1 to June 30, 2023, at the University of Gondar Comprehensive Specialized Hospital. The present study included a total of 300 patients with hypothyroidism prospectively using the systematic random sampling technique...
2024: Journal of Blood Medicine
https://read.qxmd.com/read/38544723/incidence-and-predictors-of-loss-to-follow-up-among-adult-patients-receiving-antiretroviral-therapy-in-central-ethiopia-a-multi-center-retrospective-cohort-study
#7
JOURNAL ARTICLE
Asfaw Anulo, Addisu Girma, Gezahegn Tesfaye, Fekede Asefa, Abera Cheru, Arega Abebe Lonsako
BACKGROUND: Globally, loss to follow-up (LTFU) remains a significant public health concern despite the rapid expansion of antiretroviral medication programs. It is a significant cause of treatment failure and threatens the enhancement of HIV treatment outcomes among patients on antiretroviral therapy (ART). However, there is a paucity of evidence on its incidence and predictors in Ethiopia. Thus, this study aimed to examine the incidence and predictors of LTFU among adult HIV patients receiving ART at hospitals in Central Ethiopia...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38543096/effect-of-botulinum-toxin-injections-in-the-treatment-of-spasticity-of-different-etiologies-an-umbrella-review
#8
REVIEW
Iris Otero-Luis, Arturo Martinez-Rodrigo, Iván Cavero-Redondo, Nerea Moreno-Herráiz, Irene Martínez-García, Alicia Saz-Lara
BACKGROUND: Spasticity is a very common neurological sequelae that significantly impacts the quality of life of patients, affecting more than 12 million people worldwide. Botulinum toxin is considered a reversible treatment for spasticity, but due to the large amount of available evidence, synthesis seems necessary. Therefore, we conducted an overview of existing systematic reviews and meta-analyses to evaluate the effect of botulinum toxin injections in the treatment of spasticity of different etiologies...
February 28, 2024: Pharmaceuticals
https://read.qxmd.com/read/38542695/the-effects-of-cranberry-consumption-on-glycemic-and-lipid-profiles-in-humans-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Xiangrui Li, Wenqing Chen, Jiayue Xia, Da Pan, Guiju Sun
This study aims to update the evidence and clarify whether cranberry possesses lipid-lowering and hypoglycemic properties in humans. PubMed, Web of Science, and Scopus were searched to identify relevant articles published up to December 2023. In total, 3145 publications were reviewed and 16 of them were included for qualitative synthesis and meta-analysis. Stata 15.0 and Review Manager 5.4 were applied for statistical analyses. The results revealed a significant decrease in the total cholesterol to high-density lipoprotein cholesterol ratio (TC/HDL-C) (MD = -0...
March 9, 2024: Nutrients
https://read.qxmd.com/read/38541634/comparative-analysis-of-antithrombotic-therapy-outcomes-in-mild-traumatic-brain-injury-patients-a-focus-on-bleeding-risk-and-hospital-stay-duration
#10
JOURNAL ARTICLE
Antonio Desai, Dana Shiffer, Mauro Giordano, Alice Giotta Lucifero, Elena Generali, Francesco Reggiani, Marta Calatroni, Gabriele Savioli, Sabino Luzzi, Antonio Voza
BACKGROUND: Traumatic brain injury (TBI) in the elderly is a noteworthy pathology due to the exponential increase in population age, and the effects of antiplatelet and anticoagulation on patients' outcomes are still a matter of dispute. The aim of the present study was to evaluate the impact of various antithrombotic agents on patients with mild TBI, focusing on the risk of intracranial bleeding (ICH) and length of hospitalization (LOS). METHODS: A retrospective analysis was conducted, including patients with a diagnosis of TBI admitted to the Emergency Department between 2021 and 2022...
February 27, 2024: Life
https://read.qxmd.com/read/38540551/measuring-occupational-well-being-indicators-scale-construction-and-validation
#11
JOURNAL ARTICLE
Hanvedes Daovisan, Ungsinun Intarakamhang
The purpose of this study is to carry out the scale development of occupational well-being (OWB) (affective, professional, social, cognitive, psychological and psychosomatic well-being) in Laos. Using multiple sampling data, we developed a valid OWB scale with a large Laotian sample ( n = 1745). The validity of the OWB-47 scale was analyzed using exploratory factor analysis (EFA). Cross-validity, the initial model, and confirmatory factor analysis (CFA) were performed using Stata 19 to assess the validity of the scale development...
March 19, 2024: Behavioral Sciences
https://read.qxmd.com/read/38539158/coverage-and-determinants-of-hiv-testing-and-counseling-services-among-mothers-attending-antenatal-care-in-sub-saharan-african-countries-a-multilevel-analysis
#12
JOURNAL ARTICLE
Temam Beshir Raru, Bedasa Taye Merga, Alemayehu Deressa, Abdi Birhanu, Galana Mamo Ayana, Belay Negash, Mulugeta Gamachu, Addisu Alemu, Fila Ahmed Hassen, Ahmed Mohammed, Dawit Firdisa, Lemma Demissie Regassa
BACKGROUND: HIV/AIDS is one of the top global public health threats that causes significant cases, deaths, and socioeconomic impact. Even though both HIV testing and counseling are identified as essential HIV interventions during pregnancy, large population-representative data shows that service coverage and determinants are limited. Therefore, this study aimed to assess the coverage and determinants of HIV testing and counseling services among pregnant mothers attending antenatal care services in sub-Saharan African countries using different nationwide data...
March 27, 2024: BMC Public Health
https://read.qxmd.com/read/38538352/-meta-analysis-of-the-predictive-efficacy-of-various-derived-indicators-of-sequential-organ-failure-assessment-in-outcomes-of-patients-with-sepsis
#13
JOURNAL ARTICLE
Wen Li, Zhiling Zhao, Qingtao Zhou, Qinggang Ge
OBJECTIVE: To systematically review and evaluate the predictive efficacy of various derived indicators of sequential organ failure assessment (SOFA) in mortality rate of sepsis patients. METHODS: Literature on sepsis and SOFA scores were searched in PubMed, Embase and Cochrane Library. The retrieval time will be set to the time of database-building to February, 2023. The main outcome measures included 28-day mortality, 30-day mortality, in-hospital mortality, intensive care unit (ICU) mortality and long-term mortality...
March 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/38538305/the-predictive-value-of-confusion-assessment-method-intensive-care-unit-and-intensive-care-delirium-screening-checklist-for-delirium-in-critically-ill-patients-in-the-intensive-care-unit-a-systematic-review-and-meta-analysis
#14
REVIEW
Yujie Diao, Xiaomin Yu, Qin Zhang, Xiaoli Chen
BACKGROUND: Approximately 16%-89% of patients developed delirium during hospitalization in the intensive care unit (ICU). Studies on the accuracy and clinical application of ICU delirium screening tools exist, but the results are inconsistent. Moreover, the accuracy of different screening tools varied greatly. AIM: To compare the diagnostic accuracy of Confusion Assessment Method-Intensive Care Unit (CAM-ICU) and Intensive Care Delirium Screening Checklist (ICDSC) for delirium screening in critically ill patients in the ICU...
March 27, 2024: Nursing in Critical Care
https://read.qxmd.com/read/38538222/the-impact-of-pcsk9-gene-polymorphisms-on-ischemic-stroke-a-systematic-review-and-meta-analysis
#15
Jianhong Wang, Shuang Li, Yi Ren, Guiquan Wang, Weirong Li
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in the proprotein convertase subtilisin/kexin type 9 ( PCSK9 ) gene are known to be associated with susceptibility to several cerebrovascular diseases, including ischemic stroke (IS). The aims of this study was to evaluate associations between PCSK9 gene polymorphisms and the risk of IS. Based on previous reports linking PCSK9 SNPs to plasma lipid levels and to atherosclerosis, and to inconsistencies in the reported associations between the SNPs, plasma lipid levels and IS risk, we choose the PCSK9 rs505151, rs529787, and rs17111503 to performe the association analysis...
March 20, 2024: Journal of Integrative Neuroscience
https://read.qxmd.com/read/38537444/adding-chinese-herbal-medicine-bath-therapy-to-conventional-therapies-for-psoriasis-vulgaris-a-systematic-review-with-meta-analysis-of-randomised-controlled-trials
#16
JOURNAL ARTICLE
Junyue Wang, Claire Shuiqing Zhang, Anthony Lin Zhang, Haiming Chen, Charlie Changli Xue, Chuanjian Lu
BACKGROUND: Chinese herbal medicine (CHM) bath is commonly used in China as an adjuvant therapy for managing psoriasis vulgaris. Previous systematic reviews showed that CHM bath therapy was effective and safe for psoriasis vulgaris, however, without exploration of the specifics of CHM bath therapy such as the optimal temperature, duration of each session, and the total treatment duration. PURPOSE: To evaluate the add-on effects of CHM bath therapy to conventional therapies for adult psoriasis vulgaris...
February 1, 2024: Phytomedicine
https://read.qxmd.com/read/38537056/perioperative-outcomes-and-long-term-survival-of-cryosurgery-on-unresectable-pancreatic-cancer-a-systematic-review-and-meta-analysis
#17
JOURNAL ARTICLE
Kang Xue, Xiaofeng Liu, Xiaolin Xu, Li Wang, Bole Tian
BACKGROUND: Pancreatic cancer (PC) continues to rank as one of the deadliest forms of cancer, with the majority of patients being diagnosed with unresectable disease. The implementation of cryoablation-based comprehensive treatment is expected to lead to a reduction in tumor size and potentially achieve complete resection. However, the availability of systematic and evidence-based treatment guidelines for cryoablation in pancreatic cancer is currently limited. MATERIALS AND METHODS: A computerized search was conducted in the Medline, Embase, Cochrane Library databases, and Clinicaltrials to retrieve studies published from August 1987 to June 2023...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38536886/socio-economic-disparities-and-predictors-of-fertility-among-adolescents-aged-15-to-19-in-zambia-evidence-from-the-zambia-demographic-and-health-survey-2018
#18
JOURNAL ARTICLE
Samson Shumba, Vanessa Moonga, Thomas Osman Miyoba, Stephen Jere, Jessy Mutale Nkonde, Peter Mumba
Globally, 12 million girls aged 15-19 give birth each year, and Africa hosts 19% of youth aged 15-24. In Zambia, 29% of adolescents experience childbirth, with variations by age. Projections suggest a continued rise in these trends by 2030. Zambia came up with Adolescent Health Strategic Plan 2011-2015 among the specific policies being advocated for was Adolescent-Friendly Health Services (ADFHS) in order to mitigate among others adolescent fertility. The study aims to investigate socio-economic disparities and predictors of fertility in Zambian adolescents aged 15 to 19...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536824/copayment-mechanism-in-selected-districts-of-uganda-availability-market-share-and-price-of-quality-assured-artemisinin-based-combination-therapies-in-private-drug-outlets
#19
JOURNAL ARTICLE
Moses Ocan, Winnie Nambatya, Caroline Otike, Loyce Nakalembe, Sam Nsobya
BACKGROUND: Malaria remains one of the leading causes of morbidity, and mortality in Uganda. A large proportion of malaria symptomatic patients seek healthcare in private sector. However, availability and affordability are major barriers to access to effective treatment. The private sector copayment mechanism in Uganda aims to increase availability and affordability of antimalarial agents. Our study assessed availability, price, and market share of quality assured artemisinin-based combination therapies (QAACTs) in private drug outlets in selected districts during the implementation of copayment mechanism...
2024: PloS One
https://read.qxmd.com/read/38536804/prevalence-of-physical-violence-against-people-in-insecure-migration-status-a-systematic-review-and-meta-analysis
#20
JOURNAL ARTICLE
Alexandria Innes, Sophie Carlisle, Hannah Manzur, Elizabeth Cook, Jessica Corsi, Natalia V Lewis
OBJECTIVES: This study summarised evidence on the prevalence of interpersonal, community and state physical violence against people in insecure migration status. METHODS: We conducted a systematic review and meta-analysis of primary studies that estimated prevalence of physical violence against a population in insecure migration status. We searched Embase, Social Policy and Practice, Political Science Complete, SocINDEX and Web of Science Social Sciences Citation Index for reports published from January 2000 until 31 May 2023...
2024: PloS One
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