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https://www.readbyqxmd.com/read/29049220/the-association-between-ccnd1-g870a-polymorphism-and-colorectal-cancer-risk-a-meta-analysis
#1
Mei Xie, Fen Zhao, Xiaoling Zou, Shuai Jin, Shaoquan Xiong
BACKGROUND: CyclinD1 (CCND1) is a key cell cycle regulatory protein. A large number of epidemiological studies have assessed the potential correlation between the CCND1 G870A polymorphism and the risk of colorectal cancer (CRC), but their findings have been inconsistent. To obtain a more precise understanding of the association between the G870A polymorphism in the CCND1 gene and the CRC risk, we conducted a more comprehensive meta-analysis. METHODOLOGY: We searched PubMed, Ovid, Springer, Weipu, China National Knowledge Infrastructure (CNKI), and Wanfang databases, covering all publications (the last search was updated on January 10, 2017)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049177/association-of-bmp-14-rs143383-ploymorphism-with-its-susceptibility-to-osteoarthritis-a-meta-analysis-and-systematic-review-according-to-prisma-guideline
#2
Yi Yin, Yan Wang
BACKGROUND: Osteoarthritis (OA) is a complex disease which can be caused by both environmental and genetic factors. A functional locus rs143383 of bone morphogenetic protein-14 (BMP-14) has been pointed out to be associated with OA etiology, but conflicting conclusions have been reached. To provide a more comprehensive conclusion about this issue, we performed this meta-analysis. METHODS: Relevant studies were searched from electronic databases including PubMed, Chinese National Knowledge Infrastructure, Embase, and Wanfang...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29048974/strengthening-the-working-alliance-through-a-clinician-s-familiarity-with-the-12-step-approach
#3
Cory B Dennis, Brian D Roland, Barry M Loneck
BACKGROUND: The working alliance plays an important role in the substance use disorder treatment process. Many substance use disorder treatment providers incorporate the 12-Step approach to recovery into treatment. With the 12-Step approach known among many clients and clinicians, it may well factor into the therapeutic relationship. OBJECTIVE: We investigated how, from the perspective of clients, a clinician's level of familiarity with and in-session time spent on the 12-Step approach might affect the working alliance between clients and clinicians, including possible differences based on a clinician's recovery status...
October 19, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29046732/effect-of-a-diet-containing-folate-and-hazelnut-oil-capsule-on-the-methylation-level-of-the-adrb3-gene-lipid-profile-and-oxidative-stress-in-overweight-or-obese-women
#4
Raquel Patrícia Ataíde Lima, Rayner Anderson Ferreira do Nascimento, Rafaella Cristhine Pordeus Luna, Darlene Camati Persuhn, Alexandre Sérgio da Silva, Maria da Conceição Rodrigues Gonçalves, Alessio Tony Cavalcanti de Almeida, Ronei Marcos de Moraes, Eliseu Verly Junior, Emmanuelle Fouilloux-Meugnier, Hubert Vidal, Luciano Pirola, Marciane Magnani, Naila Francis Paulo de Oliveira, Patrícia Oliveira Prada, Maria José de Carvalho Costa
BACKGROUND: Studies of genes that play an important role in the development of obesity are needed, especially studies focusing on genes that regulate food intake and affect nutrient metabolism. For example, the beta-3 adrenergic receptor (ADRB3) responds to noradrenaline and mediates lipolysis in adipocytes. METHODS: This was a controlled intervention study involving 40 overweight and obese adult women in which food intake, anthropometric measurements, biochemical analyses, and methylation levels of the ADRB3 gene were evaluated before and after intervention...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/29046404/cranberry-reduces-the-risk-of-urinary-tract-infection-recurrence-in-otherwise-healthy-women-a-systematic-review-and-meta-analysis
#5
Zhuxuan Fu, DeAnn Liska, David Talan, Mei Chung
Background: Cranberry (Vaccinium spp.) has been advocated for treatment of urinary tract infection (UTI); however, its efficacy is controversial. Women have a 50% risk of UTI over their lifetime, and ∼20-30% experience a subsequent UTI recurrence.Objective: We conducted this meta-analysis to assess the effect of cranberry on the risk of UTI recurrence in otherwise healthy women.Methods: Literature published before January 2011 was obtained from 2 published systematic reviews, and we conducted updated searches in EMBASE and MEDLINE (through July 2017)...
October 18, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/29045636/the-diagnostic-accuracy-of-the-ascertain-dementia-8-questionnaire-for-detecting-cognitive-impairment-in-primary-care-in-the-community-clinics-and-hospitals-a-systematic-review-and-meta-analysis
#6
Hsin-Hao Chen, Fang-Ju Sun, Tzu-Lin Yeh, Hsueh-Erh Liu, Hsiu-Li Huang, Benjamin Ing-Tiau Kuo, Hsin-Yi Huang
Background: The prevalence of cognitive impairment is increasing due to the aging population, and early detection is essential clinically. The Ascertain Dementia 8 (AD8) questionnaire is a brief informant-based measure recently developed to assess early cognitive impairment, however, its overall diagnostic performance is controversial. The objective of this meta-analysis was to assess the diagnostic accuracy of the AD8 for cognitive impairment. Methods: All relevant studies were collected from databases including MEDLINE, EMBASE and the Cochrane Library up to April 2017...
October 14, 2017: Family Practice
https://www.readbyqxmd.com/read/29043878/the-association-between-homocysteine-and-systemic-sclerosis-a-review-of-the-literature-and-meta-analysis
#7
Yan-Jie Zhang, Li Zhang, Xiao-Lei Huang, Yu Duan, Li-Juan Yang, Jing Wang
OBJECTIVES: The main objective of this study was to summarize the existing evidence and quantitatively evaluate whether serum/plasma levels of homocysteine (Hcy) were associated with sclerosis (SSc) diseases by performing a meta-analysis of previous studies. METHODS: PubMed, Elsevier ScienceDirect and Cochrane Library databases were used to obtain all relative published literatures. Stata version 11.0 (StataCorp, College Station, TX) was used for statistical analysis...
October 18, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/29043708/comparison-of-in-vitro-fertilization-intracytoplasmic-sperm-injection-cycle-outcome-in-patients-with-and-without-polycystic-ovary-syndrome-a-modified-poisson-regression-model
#8
Amir Almasi-Hashiani, Mohammad Ali Mansournia, Mahdi Sepidarkish, Samira Vesali, Azadeh Ghaheri, Arezoo Esmailzadeh, Reza Omani-Samani
Background: Polycystic ovary syndrome (PCOS) is a frequent condition in reproductive age women with a prevalence rate of 5-10%. This study intends to determine the relationship between PCOS and the outcome of assisted reproductive treatment (ART) in Tehran, Iran. MATERIALS AND METHODS: In this historical cohort study, we included 996 infertile women who referred to Royan Institute (Tehran, Iran) between January 2012 and December 2013. PCOS, as the main variable, and other potential confounder variables were gathered...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29043086/hepatitis-b-vaccination-coverage-and-the-determinants-of-vaccination-among-health-care-workers-in-selected-health-facilities-in-lusaka-district-zambia-an-exploratory-study
#9
Namwaka Mungandi, Mpundu Makasa, Patrick Musonda
BACKGROUND: Hepatitis B is a viral infection of the liver and causes both acute and chronic disease. It is transmitted through contact with an infected person's bodily fluids. It is an occupational hazard for healthcare workers and can be prevented by the administration of a vaccine. It is recommended that healthcare workers be vaccinated against vaccine preventable diseases including hepatitis B. The study objective was to determine the prevalence and determinants of hepatitis B vaccination among healthcare workers in selected health facilities in Lusaka...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29042393/effects-of-polyethylene-glycol-2-l-alone-or-with-ascorbic-acid-compared-with-polyethylene-glycol-4-l-alone-for-bowel-preparation-before-colonoscopy-protocol-for-a-systematic-review-and-network-meta-analysis
#10
Xu Tian, Wei-Qing Chen, Jie-Li Huang, Lan-Ying He, Bang-Lun Liu, Xi Liu, Hang Zhou, Bing-Rong Liu
INTRODUCTION: Colonoscopy has been regarded as a standard method of detecting and removing gastrointestinal lesions early, while adequate bowel preparation is the prerequisite of determining the diagnostic accuracy and treatment safety of this process. Polyethylene glycol (PEG) based bowel preparation regimens remain the first recommendation, but the optimal option is still uncertain. The aim of this systematic review and network meta-analysis of randomised controlled trials (RCTs) is to determine the optimal PEG based bowel preparation regimen before colonoscopy...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042340/mental-and-emotional-self-help-technology-apps-cross-sectional-study-of-theory-technology-and-mental-health-behaviors
#11
Benjamin T Crookston, Joshua H West, P Cougar Hall, Kaitana Martinez Dahle, Thomas L Heaton, Robin N Beck, Chandni Muralidharan
BACKGROUND: Mental and emotional self-help apps have emerged as potential mental illness prevention and treatment tools. The health behavior theory mechanisms by which these apps influence mental health-related behavior change have not been thoroughly examined. OBJECTIVE: The objective of this study was to examine the association between theoretical behavior change mechanisms and use of mental and emotional self-help apps and whether the use of such apps is associated with mental health behaviors...
October 17, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29042250/eating-breakfast-and-snacks-while-television-viewing-are-associated-with-some-cardio-metabolic-risk-factors-among-iranian-children
#12
Saeed Ghobadi, Shiva Faghih
AIM: We aimed to investigate the association of eating meals while television viewing (TVV) and screen-based behaviors with cardio metabolic risk factors (CRFs) among school-aged children in Shiraz. MATERIALS AND METHODS: This cross-sectional study was done on 409 primary school children (217 boys), aged 6-9 years. Physical activity, time spent on screen-based behaviors and frequency of eating meals while TVV were measured using a questionnaire. Anthropometric indices, fasting blood sugar (FBS), blood lipids, blood pressure (BP), dietary intakes and physical activity were assessed...
September 22, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29041797/geographical-distribution-and-profile-of-medical-doctors-in-public-sector-hospitals-of-the-limpopo-province-south-africa
#13
Samuel T Ntuli, Edwin Maboya
BACKGROUND: The shortage and unequal distribution of medical doctors in low- and middle-income countries continues to be a public health concern. OBJECTIVE: To establish the geographical distribution and demographic profile of medical doctors in public sector hospitals of the Limpopo Province, South Africa. METHOD: The PERSAL system was used to obtain information on the number of medical doctors employed in public sector hospitals of the Limpopo Province...
September 27, 2017: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29039175/-comparison-of-limus-eluting-stent-with-paclitaxel-eluting-stent-for-patients-with-coronary-small-vessel-disease-a-systematic-review-and-meta-analysis
#14
Xiaoqun Zhang, Qiwen Wang, Xin Wang, Xiaolei Xu, Jianhua Zhu
OBJECTIVE: To compare the efficacy of limus-eluting stent (LES) with paclitaxel-eluting stent (PES) for patients with coronary small vessel disease. METHODS: The studies of LES and PES used for patients with coronary small vessel disease were searched in PubMed, Web of Science, ClinicalTrials, SinoMed, CNKI, Wanfang data and CQVIP. The relative risk (RR) estimates with 95% confidence intervals and other statistical variables were calculated with Stata 14.0, and the meta analysis was performed with RevMan 5...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29036846/perceptions-of-sexuality-in-individuals-with-amyotrophic-lateral-sclerosis-als-and-their-treating-clinicians
#15
Mona Shahbazi, Shara Holzberg, Saeyoan Thirunavukkarasu, Gioia Ciani
INTRODUCTION: Amyotrophic Lateral Sclerosis (ALS) may not affect an individual's sexual function directly, but it can indirectly impact their sexual activity. Sexual partners often become caregivers, diminishing sexuality within a relationship. This can result in decline of quality of life. OBJECTIVE: The study aimed to explore the perspectives of individuals with ALS and their treating clinicians regarding the importance of sexuality in rehabilitation within a multidisciplinary ALS center...
October 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29035442/long-noncoding-rna-pvt1-as-a-potent-predictor-of-prognosis-in-cancers-a-meta-analysis
#16
Xuefeng Pan, Baohui Li, Naijun Fan, Juntang Li, Fengbo Cai, Guang Zhao, Guobao Zheng, Chunfang Gao
BACKGROUND: Plasmacytoma variant translocation 1 (PVT1), an oncogenic long noncoding RNA located in a recognized cancer-risk gene region-8q24, is significantly overexpressed in various cancers. Many studies have found that high expression of PVT1 was correlated with poor prognosis. METHODS: This meta-analysis was performed by searching electronic databases Pubmed, Web of Science, Chinese National Knowledge Infrastructure, WanFang, and ChongQing VIP for eligible papers on the prognostic impact and clinicopathological characteristics of PVT1 expression in cancer from inception to January 31, 2017...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29035163/uptake-and-correlates-of-cervical-cancer-screening-among-hiv-infected-women-attending-hiv-care-in-uganda
#17
Rhoda K Wanyenze, John Baptist Bwanika, Jolly Beyeza-Kashesya, Shaban Mugerwa, Jim Arinaitwe, Joseph K B Matovu, Violet Gwokyalya, Dickson Kasozi, Justine Bukenya, Fred Makumbi
BACKGROUND: Human immunodeficiency virus (HIV)-infected women are at high risk of cervical cancer. OBJECTIVE: This study assessed uptake and correlates of cervical screening among HIV-infected women in care in Uganda. METHODS: A nationally representative cross-sectional survey of HIV-infected women in care was conducted from August to November 2016. Structured interviews were conducted with 5198 women aged 15-49 years, from 245 HIV clinics...
2017: Global Health Action
https://www.readbyqxmd.com/read/29033311/brain-gray-matter-changes-in-type-2-diabetes-mellitus-a-meta-analysis-of-whole-brain-voxel-based-morphometry-study
#18
Guangyao Wu, Lin Lin, Qing Zhang, Jianlin Wu
AIMS: We aimed to identify alterations in global gray matter volumes (GMV) and consistent regional abnormalities in T2DM patients via meta-analysis. METHODS: A systematic search for relevant studies indexed in the PubMed and Embase databases was conducted. A quantitative meta-analysis of volumetric and whole-brain VBM data was conducted using STATA v.12.0 and AES-SDM software packages, respectively. RESULTS: A total of 15 volumetric studies and five VBM studies of GM in T2DM patients vs...
September 15, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29026874/australia-and-new-zealand-islets-and-pancreas-transplant-registry-annual-report-2017-pancreas-waiting-list-recipients-and-donors
#19
Angela C Webster, James Hedley, Abhijit Patekar, Paul Robertson, Patrick J Kelly
This is a registry report from the Australia and New Zealand Islet and Pancreas Transplant Registry. We report data for all solid organ pancreas transplant activity from inception in 1984 to end of 2016. Data analysis was performed using Stata Software version 14 (StataCorp, College Station, Tex). From 1984 to 2016 a total of 756 solid organ pancreas transplants have been performed in Australia and New Zealand, in 738 individuals. In 2016, 55 people received a pancreas transplant. These transplants were performed in Auckland (4), Monash (22), and Westmead (29)...
October 2017: Transplantation Direct
https://www.readbyqxmd.com/read/29026763/comparative-evaluation-of-indian-diabetes-risk-score-and-finnish-diabetes-risk-score-for-predicting-risk-of-diabetes-mellitus-type-ii-a-teaching-hospital-based-survey-in-maharashtra
#20
Shivshakti D Pawar, Jayashri D Naik, Priya Prabhu, Gajanan M Jatti, Sachin B Jadhav, B K Radhe
CONTEXT: India is currently becoming capital for diabetes mellitus. This significantly increasing incidence of diabetes putting an additional burden on health care in India. Unfortunately, half of diabetic individuals are unknown about their diabetic status. Hence, there is an emergent need of effective screening instrument to identify "diabetes risk" individuals. AIMS: The aim is to evaluate and compare the diagnostic accuracy and clinical utility of Indian Diabetes Risk Score (IDRS) and Finnish Diabetes Risk Score (FINDRISC)...
January 2017: Journal of Family Medicine and Primary Care
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