Jessica Warnink-Kavelaars, Lisanne E de Koning, Annelies E van der Hulst, Annemieke I Buizer, Nicole Poissonnier, Laura E Wijninga, Leonie A Menke, Laura Muiño Mosquera, Lies Rombaut, Raoul H H Engelbert
Children with Marfan (MFS) and Loeys-Dietz syndrome (LDS) report limitations in physical activities, sports, school, leisure, and work participation in daily life. This observational, cross-sectional, multicenter study explores associations between physical fitness and cardiovascular parameters, systemic manifestations, fatigue, and pain in children with MFS and LDS. Forty-two participants, aged 6-18 years (mean (SD) 11.5(3.7)), diagnosed with MFS (n = 36) or LDS (n = 6), were enrolled...
March 11, 2024: European Journal of Pediatrics