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https://www.readbyqxmd.com/read/29035687/acute-glutamine-ingestion-modulates-lymphocytic-responses-to-exhaustive-exercise-in-the-heat
#1
Chen Zheng, Xiang-Ke Chen, Yue Zhou
The purpose of this study was to determine if acute intake of glutamine modulates homeostatic, hematologic, immune, and inflammatory responses to exhaustive exercise in the heat. Thirteen healthy untrained young men participated in this randomized, double-blind, placebo-controlled, crossover study. They served as their own control and completed two trials of treadmill exercise at 40% VO2max to exhaustion in a hot environment (38.0 ± 1.0 °C, 60.0 ± 5.0 % relative humidity, and 20.8% oxygen) following placebo (PLA) and glutamine (GLN) consumption...
October 16, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29033851/effects-of-alpha-lactalbumin-or-whey-protein-isolate-on-muscle-damage-muscle-pain-and-mood-states-following-prolonged-strenuous-endurance-exercise
#2
Lu Qin, Stephen H S Wong, Feng-Hua Sun, Yu Huang, Sinead Sheridan, Cindy H P Sit
This study compared the effect of alpha-lactalbumin and whey protein on muscle damage, muscle pain, and mood states during short term recovery following strenuous prolonged exercise. In a two-stage crossover counterbalanced design, 12 endurance male runners were recruited (age: 30.4 ± 2.8 year, height: 172.7 ± 5.6 cm, body mass: 66.7 ± 6.5 kg, VO2max: 58.0 ± 6.9 ml/kg(-)/min), ran for 90 min at 70% VO2max, and followed by a 4-h recovery. Two treatments (carbohydrate+alpha-lactalbumin, CA; carbohydrate+whey protein isolate, CW) were applied during the main trials...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29031455/does-permanent-atrial-fibrillation-modify-response-to-cardiac-resynchronization-therapy-in-heart-failure-patients
#3
Ana Abreu, Mário Oliveira, Pedro Silva Cunha, Helena Santa Clara, Guilherme Portugal, Inês Gonçalves Rodrigues, Vanessa Santos, Luis Morais, Mafalda Selas, Rui Soares, Luísa Branco, Rui Ferreira, Miguel Mota Carmo
INTRODUCTION: The benefits of cardiac resynchronization therapy (CRT) documented in heart failure (HF) may be influenced by atrial fibrillation (AF). We aimed to compare CRT response in patients in AF and in sinus rhythm (SR). METHODS: We prospectively studied 101 HF patients treated by CRT. Rates of clinical, echocardiographic and functional response, baseline NYHA class and variation, left ventricular ejection fraction, volumes and mass, atrial volumes, cardiopulmonary exercise test (CPET) duration (CPET dur), peak oxygen consumption (VO2max) and ventilatory efficiency (VE/VCO2 slope) were compared between AF and SR patients, before and at three and six months after implantation of a CRT device...
October 12, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29029009/the-effect-of-physical-activity-and-cardiorespiratory-fitness-on-all-cause-mortality-in-hong-kong-chinese-older-people
#4
Zhihui Lu, Jean Woo, Timothy Kwok
Background: It is unclear whether physical activity (PA) could predict all-cause mortality independently of cardiorespiratory fitness, and there are relatively few studies evaluating the combined effect of PA and cardiorespiratory fitness on mortality. Methods: We invited 1,242 Chinese older adults aged 69 to 94 years from the MrOs and MsOs cohort (Hong Kong) study for a 7-year follow-up. PA was measured by the Physical Activity Scale of the Elderly (PASE). Cardiorespiratory fitness, expressed as maximal oxygen uptake (VO2max), was assessed by performing symptom-limited maximal exercise testing on an electrically braked bicycle ergometer and 6-meter walk test...
September 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29027266/reliable-and-sensitive-physical-testing-of-elite-trapeze-sailors
#5
Jonathan Bay, Jens Bojsen-Møller, Nikolai B Nordsborg
It was investigated, if a newly developed discipline specific test for elite-level trapeze sailors is reli-able and sensitive. Furthermore, the physical demands of trapeze sailing were examined. In part 1, nine national team athletes were accustomed to a simulated sailing test, which subsequently was completed on four occasions to determine test reliability and sensitivity to manipulations in body-weight. Rope-pulling mean power output (MPO), oxygen consumption (VO2 ), heart rate (HR) and blood lactate values were acquired in all trials...
October 13, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29025406/impact-of-empagliflozin-on-subclinical-left-ventricular-dysfunctions-and-on-the-mechanisms-involved-in-myocardial-disease-progression-in-type-2-diabetes-rationale-and-design-of-the-empa-heart-trial
#6
Andrea Natali, Lorenzo Nesti, Iacopo Fabiani, Enrico Calogero, Vitantonio Di Bello
BACKGROUND: Asymptomatic left ventricular (LV) dysfunction is highly prevalent in type 2 diabetes patients. Unlike the other hypoglycemic drugs, SGLT2 inhibitors have shown potential benefits for reducing cardiovascular death and risk factors, aside from lowering plasma glucose levels. With this study we aim at determining whether the treatment with empagliflozin is associated with an improvement in LV functions in diabetic patients with asymptomatic LV dysfunction against Sitagliptin, which is presumably neutral on myocardial function...
October 12, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29024325/dose-response-effects-of-p-synephrine-on-fat-oxidation-rate-during-exercise-of-increasing-intensity
#7
Jorge Gutiérrez-Hellín, Juan Del Coso
The aim of this investigation was to determine the effects different doses of p-synephrine on maximal fat oxidation during exercise. Seventeen healthy subjects volunteered to participate in a double-blind and randomised experimental design composed of four identical experimental trials. On four trials separated by 72 h, participants ingested a placebo or 1, 2 or 3 mg/kg of p-synephrine. After resting for 60 min to allow substance absorption, participants performed an exercise test of increasing intensity on a cycle ergometer while gas exchange was measured continuously...
October 11, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29021828/endurance-exercise-training-decreased-serum-levels-of-surfactant-protein-d-and-improved-aerobic-fitness-of-obese-women-with-type-2-diabetes
#8
Sajjad Rezaei, Mahdieh Molanouri Shamsi, Mehdi Mahdavi, Azadeh Jamali, Jonato Prestes, Ramires Alsamir Tibana, James Wilfred Navalta, Fabrício Azevedo Voltarelli
BACKGROUND: Surfactant protein D (SP-D) is a member of the collectin family and is an important component of the pulmonary innate host defense. To find the relationship between exercise training and SP-D in diabetes, we examined the possible effects of a 10-week endurance exercise-training program on serum levels of SP-D, leptin, lipid profile and insulin resistance in obese women with type-2 diabetes mellitus (T2DM). METHODS: Twenty-two obese women with T2DM were randomly assigned to either exercise training (ET) or control (C) group...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29018351/upper-body-muscular-endurance-training-improves-performance-following-50-min-of-double-poling-in-well-trained-cross-country-skiers
#9
Jørgen Børve, Steffen N Jevne, Bjarne Rud, Thomas Losnegard
This study investigated the effect of muscular endurance training on O2-cost and performance in double poling (DP) on a rollerski treadmill. Twenty-two well-trained cross-country skiers (31 ± 4 years, 77 ± 9 kg, 181 ± 8 cm, VO2max running: 64 ± 5 mL·kg(-1)·min(-1)) were counter-balanced to either a combined muscular endurance and running interval training group [MET; n = 11 (♂ = 9, ♀ = 2)], or an endurance running interval training group [ET; n = 11 (♂ = 9, ♀ = 2)]. Both groups continued their normal low-and moderate intensity training, but replaced 2 weekly high intensity-training sessions with two project-specific sessions for 6 weeks...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29016241/analysing-a-cycling-grand-tour-can-we-monitor-fatigue-with-intensity-or-load-ratios
#10
Dajo Sanders, Mathieu Heijboer, Matthijs K C Hesselink, Tony Myers, Ibrahim Akubat
This study evaluated the changes in ratios of different intensity (rating of perceived exertion; RPE, heart rate; HR, power output; PO) and load measures (session-RPE; sRPE, individualized TRIMP; iTRIMP, Training Stress Score™; TSS) in professional cyclists. RPE, PO and HR data was collected from twelve professional cyclists (VO2max 75 ± 6 ml∙min∙kg(-1)) during a two-week baseline training period and during two cycling Grand Tours. Subjective:objective intensity (RPE:HR, RPE:PO) and load (sRPE:iTRIMP, sRPE:TSS) ratios and external:internal intensity (PO:HR) and load (TSS:iTRIMP) ratios were calculated for every session...
October 10, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28988307/effects-of-normoxic-and-hypoxic-exercise-regimens-on-lymphocyte-apoptosis-induced-by-oxidative-stress-in-sedentary-males
#11
Jong-Shyan Wang, Yi-Ching Chen, Wan-Ling Chen, Chin-Pu Lin
PURPOSE: Oxidative stress-induced lymphocyte apoptosis is linked to hypoxemic individuals suffering from cardiopulmonary disorders or exposed to hypoxic environments. What kind of the exercise strategy under hypoxic condition improves exercise performance and simultaneously minimizes lymphocyte dysfunction caused by oxidative stress has not yet been established. This study elucidates how various exercises regimens with/without hypoxia affect lymphocyte apoptosis induced by oxidative stress...
October 7, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28988230/urinary-kidney-injury-molecule-1-but-not-urinary-neutrophil-gelatinase-associated-lipocalin-is-increased-after-short-maximal-exercise
#12
Wojciech Wołyniec, Wojciech Ratkowski, Robert Urbański, Maria Bartoszewicz, Danuta Siluk, Zuzanna Wołyniec, Katarzyna Kasprowicz, Katarzyna Zorena, Marcin Renke
BACKGROUND AND AIMS: Urinary neutrophil gelatinase associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are markers of acute kidney injury. The albuminuria is a well-known abnormality after physical exercise. The aim of this study was to investigate changes in uNGAL and uKIM-1 after intensive exercise causing albuminuria. METHODS: The study population consisted of 19 participants (10 males and 9 females). The mean age of participants was 35...
October 7, 2017: Nephron
https://www.readbyqxmd.com/read/28985267/effect-of-exercise-on-arterial-stiffness-is-there-a-ceiling-effect
#13
David Montero, Andreas Breenfeldt-Andersen, Laura Oberholzer, Thomas Haider
BACKGROUND: Whether arterial stiffness (AS) can be improved by regular exercise in healthy individuals remains equivocal according to cross-sectional and longitudinal studies assessing arterial properties at discrete time points. The purpose of the present study was to pinpoint the time course of training-induced adaptations in central AS. METHODS: Aorta characteristic impedance (Zc) and carotid distensibility (CD) were determined with ultrasonography prior to (week 0) and across 8 weeks (weeks 2, 4, and 8) of supervised endurance training (ET) (3 × 60 minutes cycle ergometry sessions per week), in 9 previously untrained healthy normotensive adults (27 ± 4 years) with no history of cardiovascular disease...
August 31, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28968656/aerobic-fitness-explains-individual-differences-in-the-functional-brain-connectome-of-healthy-young-adults
#14
Tanveer Talukdar, Aki Nikolaidis, Chris E Zwilling, Erick J Paul, Charles H Hillman, Neal J Cohen, Arthur F Kramer, Aron K Barbey
A wealth of neuroscience evidence demonstrates that aerobic fitness enhances structural brain plasticity, promoting the development of gray matter volume and maintenance of white matter integrity within networks for executive function, attention, learning, and memory. However, the role of aerobic fitness in shaping the functional brain connectome remains to be established. The present work therefore investigated the effects of aerobic fitness (as measured by VO2max) on individual differences in whole-brain functional connectivity assessed from resting state fMRI data...
September 14, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28967304/systemic-smad7-gene-therapy-increases-striated-muscle-mass-and-enhances-exercise-capacity-in-a-dose-dependent-manner
#15
Joseph Maricelli, Yemeserach Bishaw, Bo Wang, Min Du, Buel Dantese Rodgers
Striated muscle wasting occurs with a variety of disease indications, contributing to mortality and compromising life quality. Recent studies indicate that the recombinant adeno-associated viral (serotype 6) Smad7 gene therapeutic, AVGN7, enhances skeletal and cardiac muscle mass and prevents cancer-induced wasting of both tissues. This is accomplished by attenuating ActRIIb intracellular signaling and as a result, the physiological actions of myostatin and other ActRIIb ligands. AVGN7 also enhances isolated skeletal muscle twitch force, but is unknown to similarly improve systemic muscle function, especially exercise capacity...
October 1, 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/28966706/the-effect-of-psychomotor-performance-cerebral-and-arterial-blood-saturation-between-african-american-and-caucasian-males-before-during-and-after-normobaric-hypoxic-exercise
#16
Matthew R Feeback, Yongsuk Seo, Matthew Dancy, Ellen L Glickman
To further elucidate physiological and cognitive performance differences between African-American (AA) and Caucasian individuals (CAU) before, during or after hypoxic and normoxic exercise. Twelve college aged (18-25) apparently healthy African-American (six volunteers) and Caucasian (six subjects) males took part in two trials consisting of normobaric normoxia and normobaric hypoxia (12% oxygen). Each subject cycled at 50% of their altitude adjusted VO2max (-26% of normoxia VO2max) for one hour after a two-hour baseline...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28966704/assessment-of-differences-in-the-anthropometric-physiological-and-training-characteristics-of-finishers-and-non-finishers-in-a-tropical-161-km-ultra-marathon
#17
Philip Ls Tan, Frankie Hy Tan, Andrew N Bosch
This study aimed to compare and determine the differences in the physiological, anthropometric and training characteristics of the finishers (FIN) and non-finishers (N-FIN) in a 161-km race. Two groups of runners (FIN; N=12 and N-FIN; N=14) completed a series of anthropometric and physiological measurements over two separate sessions at least three weeks prior to the race. Training sessions starting from six weeks prior to the race were recorded. Sum of 7 skinfolds, arm and calf girths, VO2max and peak treadmill speed (PTS) were taken during session 1 while the lactate threshold (LT) and running economy (RE) were assessed during session 2...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28965346/impact-of-5-days-of-sprint-training-in-hypoxia-on-performance-and-muscle-energy-substances
#18
Nobukazu Kasai, Chihiro Kojima, Daichi Sumi, Hideyuki Takahashi, Kazushige Goto, Yasuhiro Suzuki
The present study was designed to determine the effect of 5 consecutive days of repeated sprint training under hypoxia on anaerobic performance and energy substances. Nineteen male sprinters performed repeated sprints for 5 consecutive days under a hypoxic (HYPO; fraction of inspired oxygen [FiO2], 14.5%) or normoxic (NOR; FiO2, 20.9%) condition. Before and after the training period, 10-s maximal sprint, repeated sprint ability (5×6-s sprints), 30-s maximal sprint, and maximal oxygen uptake (VO2max) tests were conducted...
October 1, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28965267/exercise-performance-and-quality-of-life-in-children-with-cystic-fibrosis-and-mildly-impaired-lung-function-relation-with-antibiotic-treatments-and-hospitalization
#19
Kristof Vandekerckhove, Michiel Keyzer, Jasper Cornette, Ilse Coomans, Filip Pyl, Frans De Baets, Petra Schelstraete, Filomeen Haerynck, Daniel De Wolf, Sabine Van Daele, Jan Boone
This study evaluates the impact of antibiotic treatments and hospitalization on exercise performance and health-related quality of life (QOL) in children with mild cystic fibrosis (CF) lung disease. Forty-seven children between 7 and 17 years with mild CF underwent a maximal exercise test including spiro-ergometry and filled out a QOL-questionnaire (PedsQL™). Amount of antibiotic treatments (AB) and hospitalization days in the last 3 years were reviewed. FEV1% was mildly decreased (91.7 ± 17.9 L/min, p = 0...
September 30, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28950400/standardized-met-value-underestimates-the-energy-cost-of-treadmill-running-in-men
#20
Helouane M Ázara, Paulo T V Farinatti, Adrian W Midgley, Fabrício Vasconcellos, Patrícia Vigário, Felipe A Cunha
The main purpose of the present study was to compare the reference metabolic equivalent (MET) value and observed resting oxygen uptake (VO2) for defining cardiorespiratory fitness (VO2max) and characterizing the energy cost of treadmill running. A heterogeneous cohort of 114 healthy men volunteered to participate. In Part 1 of the study, 114 men [mean±SD, age: 24±5 years; height: 177.1±7.9 cm; body mass: 75.0±10.0 kg] visited the laboratory twice for assessment of resting and maximal VO2 values to compare the reference MET value vs...
September 26, 2017: International Journal of Sports Medicine
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