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"Neonatal loss"

Mohamed Rezk, Osama Elkelani, Abdelhamid Shaheen, Awni Gamal, Hassan Badr
OBJECTIVE: to assess prospectively the maternal cardiovascular hemodynamic changes and obstetric outcome in women with rheumatic heart disease (RHD) and to detect predictors of poor outcome. METHODS: This prospective observational study included 204 pregnant patients with RHD who were divided into two groups; successful pregnancy group with living fetus (n = 126) and poor obstetric outcome group with fetal or neonatal loss (n = 78). Hemodynamic changes, maternal and fetal outcome were assessed and recorded...
April 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
Rahat Wadhwa Desai, Mary Alice Smith
About one in seven cases of listeriosis occurs in pregnant women, and, although listeriosis is rare, it is the third leading cause of death from food-borne infections. Pregnancy-related listeriosis increases the risk for fetal and neonatal mortality by approximately 21%. During pregnancy, infections are more likely to occur in the third trimester (66%) than the first trimester (3%). However, fetal and neonatal adverse effects are less common as gestational age increases or with older gestational age at birth...
March 15, 2017: Birth defects research
Suhong Qian, Wenchun Fan, Ping Qian, Huanchun Chen, Xiangmin Li
BACKGROUND: Seneca valley virus (SVV), a member of the Picornaviridae family, is a small non-enveloped RNA virus, that is linked to porcine idiopathic vesicular disease (PIVD). SVV infection in swine results in vesicular disease and epidemic transient neonatal losses (ETNL). The first case of SVV infection was reported in Guangdong, South China in 2015. RESULTS: We isolated and characterized an SVV HB-CH-2016 strain from vesicular lesion tissue specimens from piglets with PIVD in Hubei, Central China...
October 19, 2016: Virology Journal
T Sun, O L Rojas, C Li, L A Ward, D J Philpott, J L Gommerman
Although we know a great deal about which types of dendritic cells (DCs) promote T-cell priming in the periphery, less is known about which DC subset(s) provoke antiviral responses within the gut. Here we report that conventional Zbtb46-dependent DCs were critically required for antiviral CD8(+) T-cell responses against rotavirus (RV), the major cause of childhood gastroenteritis worldwide. Furthermore, we found that in adult mice, Batf3-dependent DCs were required for generating optimal RV-specific CD8(+) T-cell responses...
May 2017: Mucosal Immunology
Budhan S Pukazhenthi
Wild ungulates throughout the world face the impending risk of extinction. Small founding population size, lack of interest in exhibiting wild ungulates and declining space in zoos are not sustaining ex situ populations. Animals managed in ex situ collections continue to experience >20% neonate loss globally. To ensure population sustainability there is a critical need to: (1) manage ungulates in large herds, increasing mate choice and reproductive efficiency; (2) improve husbandry and genetic management; and (3) develop consistent assisted reproductive technologies, including sperm cryopreservation and AI...
January 6, 2016: Reproduction, Fertility, and Development
Jessica I Lundin, Gina M Ylitalo, Rebecca K Booth, Bernadita Anulacion, Jennifer A Hempelmann, Kim M Parsons, Deborah A Giles, Elizabeth A Seely, M Bradley Hanson, Candice K Emmons, Samuel K Wasser
Persistent organic pollutants (POPs), specifically PCBs, PBDEs, and DDTs, in the marine environment are well documented, however accumulation and mobilization patterns at the top of the food-web are poorly understood. This study broadens the understanding of POPs in the endangered Southern Resident killer whale population by addressing modulation by prey availability and reproductive status, along with endocrine disrupting effects. A total of 140 killer whale scat samples collected from 54 unique whales across a 4 year sampling period (2010-2013) were analyzed for concentrations of POPs...
June 21, 2016: Environmental Science & Technology
Pengtao Gong, Lili Cao, Yanbing Guo, Hang Dong, Shuxian Yuan, Xinhua Yao, Wenzhi Ren, Lin Yao, Zhilin Xu, Qiang Sun, Xichen Zhang
The intracellular parasite Toxoplasma gondii is a major cause of abortion and neonatal loss in livestock, and can cause severe illness to human with weakened immune system. The heavy incidence and severe consequence indicate the development of vaccines against T. gondii is required. In this study, DNA vaccines encoding GRA1 and MIC3 antigens were developed. The parasite-specific immune responses and protection efficiency against toxoplasmosis by these DNA vaccines were evaluated in BALB/c mice. The results demonstrated that the IgG antibody production was significantly increased in multi-antigenic vaccine encoding GRA1 and MIC3 immunized group, as well as the IFN-γ level, when compared with single-gene vaccines and controls groups (p < 0...
July 2016: Experimental Parasitology
Emily Shelkowitz, Sharon L Vessella, Patricia O'Reilly, Richard Tucker, Beatrice E Lechner
BACKGROUND: The death of a newborn is a traumatic life changing event in the lives of parents. We hypothesized that bereaved parents of newborn infants want to have choices in the personal care of their infant at the end of life. METHODS: Parents who had suffered a perinatal or neonatal loss between 1 and 6 years before the survey in a regional level IV neonatal intensive care unit (NICU) and associated labor and delivery room were invited to participate. Parents chose between an online survey, paper survey or telephone interview...
2015: BMC Palliative Care
Karen Shapiro, Melissa A Miller, Andrea E Packham, Beatriz Aguilar, Patricia A Conrad, Elizabeth Vanwormer, Michael J Murray
Toxoplasma gondii and Sarcocystis neurona are protozoan parasites with terrestrial definitive hosts, and both pathogens can cause fatal disease in a wide range of marine animals. Close monitoring of threatened southern sea otters (Enhydra lutris nereis) in California allowed for the diagnosis of dual transplacental transmission of T. gondii and S. neurona in a wild female otter that was chronically infected with both parasites. Congenital infection resulted in late-term abortion due to disseminated toxoplasmosis...
March 2016: Parasitology
L Williams, K Kennedy, R D Boss
No abstract text is available yet for this article.
October 2015: Journal of Perinatology: Official Journal of the California Perinatal Association
Sandiren Naiken, Mary-Ann Griffiths, Lindsay Edouard, Nada Padayatchy
The cynomolgus monkey is widely used in reproductive research. However, the effects on their reproductive parameters of infant and maternal factors such as birth order, sex of infants, twin births, maternal age and lactation status have not been fully examined. The aim of this retrospective study was to determine how such infant and maternal factors impact on infant birth weight, birth viability, neonatal loss and retained placenta in cynomolgus monkeys. The study was based on birth data from a cohort of 789 females over an eight-year period...
December 2015: American Journal of Primatology
Daniela N Vasquez, Andrea V Das Neves, Laura Vidal, Miriam Moseinco, Jorge Lapadula, Graciela Zakalik, Analía Santa-Maria, Raúl A Gomez, Mónica Capalbo, Claudia Fernandez, Enrique Agüero-Villareal, Santiago Vommaro, Marcelo Moretti, Silvana B Soli, Florencia Ballestero, Juan P Sottile, Viviana Chapier, Carlos Lovesio, José Santos, Fernando Bertoletti, Alfredo D Intile, Pablo M Desmery, Elisa Estenssoro
OBJECTIVE: To evaluate pregnant/postpartum patients requiring ICUs admission in Argentina, describe characteristics of mothers and outcomes for mothers/babies, evaluate risk factors for maternal-fetal-neonatal mortality; and compare outcomes between patients admitted to public and private health sectors. DESIGN: Multicenter, prospective, national cohort study. SETTING: Twenty ICUs in Argentina (public, 8 and private, 12). PATIENTS: Pregnant/postpartum (< 42 d) patients admitted to ICU...
September 2015: Critical Care Medicine
Cali E Willet, Mariano Makara, George Reppas, George Tsoukalas, Richard Malik, Bianca Haase, Claire M Wade
Spondylocostal dysostosis is a congenital disorder of the axial skeleton documented in human families from diverse racial backgrounds. The condition is characterised by truncal shortening, extensive hemivertebrae and rib anomalies including malalignment, fusion and reduction in number. Mutations in the Notch signalling pathway genes DLL3, MESP2, LFNG, HES7 and TBX6 have been associated with this defect. In this study, spondylocostal dysostosis in an outbred family of miniature schnauzer dogs is described. Computed tomography demonstrated that the condition mirrors the skeletal defects observed in human cases, but unlike most human cases, the affected dogs were stillborn or died shortly after birth...
2015: PloS One
Jane Treadwell Holston
Around 20,000 neonatal deaths occur each year, many from congenital heart defects such as hypoplastic left heart syndrome. Nurses are on the frontline of caring for families experiencing neonatal loss. Careful spiritual and cultural assessment, attention to beliefs, focusing on relationship, and helping families create legacy can assist with grieving and making meaning out of loss.
January 2015: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
Tea Meloni, Piera A Martino, Valeria Grieco, Maria C Pisu, Barbara Banco, Alessandro Rota, Maria C Veronesi
Bacterial infections represent the second cause of neonatal morbidity and mortality in dogs, so the present study aimed to investigate the bacterial involvement in canine neonatal mortality and to evaluate the antibiotic susceptibility of the isolated bacteria. Fifty-one newborn purebred puppies, born dead or dead within 28 days of age, belonging to 36 different litters, were enrolled and the following procedures were performed on their fresh dead bodies: necropsy, collection of swabs by liver, kidney, lung, small bowel, and possible thoracic and/ or abdominal effusion, for both bacteriological examination and antimicrobial susceptibility testing, and collection of samples by the same organs for histology...
December 29, 2014: Veterinaria Italiana
Christelle Robert, Pablo Fuentes-Utrilla, Karen Troup, Julia Loecherbach, Frances Turner, Richard Talbot, Alan L Archibald, Alan Mileham, Nader Deeb, David A Hume, Mick Watson
BACKGROUND: The domestic pig (Sus scrofa) is both an important livestock species and a model for biomedical research. Exome sequencing has accelerated identification of protein-coding variants underlying phenotypic traits in human and mouse. We aimed to develop and validate a similar resource for the pig. RESULTS: We developed probe sets to capture pig exonic sequences based upon the current Ensembl pig gene annotation supplemented with mapped expressed sequence tags (ESTs) and demonstrated proof-of-principle capture and sequencing of the pig exome in 96 pigs, encompassing 24 capture experiments...
July 3, 2014: BMC Genomics
Eileen K Hutton, Angela Reitsma, Julia Thorpe, Ginny Brunton, Karyn Kaufman
BACKGROUND: There has been a renewed interest in the place of birth, including intended home birth, for low risk women. In the absence of adequately-sized randomised controlled trials, a recent Cochrane review recommended that a systematic review and meta-analysis, including observational studies, be undertaken to inform this topic. The objective of this review is to determine if women intending at the onset of labour to give birth at home are more or less likely to experience a foetal or neonatal loss compared to a cohort of women who are comparable to the home birth cohort on the absence of risk factors but who intend to give birth in a hospital setting...
2014: Systematic Reviews
S Basude, L McDermott, S Newell, B Wreyford, M Denbow, J Hutchinson, S Abdel-Fattah
OBJECTIVES: To assess the accuracy of antenatal diagnosis of hemivertebra, to quantify the association with coexisting anomalies and to determine the perinatal outcome. METHOD: This was a retrospective observational study of all cases of suspected fetal or neonatal hemivertebra identified via the UK Southwest Congenital Anomaly Register (SWCAR) between 2002 and 2012. RESULTS: From a total of 88 cases of hemivertebra identified during the study period, data were obtained for 67 of them: 45 (10 isolated and 35 with coexisting anomalies) cases were suspected antenatally and 22 (10 isolated and 12 with coexisting anomalies) were diagnosed postnatally...
April 2015: Ultrasound in Obstetrics & Gynecology
Ingrid H Holmøy, Steinar Waage, Yrjö T Gröhn
A case-control study was conducted to identify ewe characteristics that affect the risk of a ewe losing at least one lamb during the first 5 days post lambing. Data were from a national sheep registry, and only ewes that lambed in the spring of 2010 belonging to flocks that reported disease events were included. Ewes registered with abortion or stillbirth were excluded. Cases (n=4850) and controls (n=85,354) from 1153 flocks were studied using logistic regression models, accounting for within flock correlation...
June 1, 2014: Preventive Veterinary Medicine
Mitike Molla Sisay, Robel Yirgu, Abebe Gebremariam Gobezayehu, Lynn M Sibley
INTRODUCTION: In Ethiopia, neonatal mortality and stillbirth are high and underreported. This study explored values related to neonatal mortality and stillbirth and the visibility of these deaths in rural Ethiopia among 3 generations of women. METHODS: We conducted a qualitative study in 6 rural districts of the Oromiya and Amhara regional states during May 2012. We included 30 focus groups representing grandmothers, married women (mothers), and unmarried girls in randomly selected kebeles (villages)...
January 2014: Journal of Midwifery & Women's Health
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