Izem Olcay Sahin, Hilal Akalin, Seyma Aktas Paskal, Busra Tan, Ezgi Yalcinkaya, Mikail Demir, Mustafa Yakubi, Busra Ozguc Caliskan, Ozlem Gokce Ekinci, Mehmet Ercan, Tugce Yasar Kucuk, Gizem Gokgoz, Aslihan Kiraz, Huseyin Per, Mahmut Tuncay Ozgun, Numan Baydilli, Yusuf Ozkul, Munis Dundar
BACKGROUND AND AIM: Chromosomal analysis is a laboratory technique used to examine the chromosomes of an individual, offering insights into chromosome numbers, structures, and arrangements to diagnose and comprehend genetic diseases. This retrospective study provides a comprehensive understanding of the distribution by indications in a large cohort of 14,242 patients and the frequency of chromosomal abnormalities in different clinical populations. METHOD: The study examined various indications for karyotype evaluation, with recurrent pregnancy loss being the most common indication, followed by intellectual disability, dysmorphic features, congenital anomalies, and developmental delay...
December 19, 2023: Journal of Clinical Laboratory Analysis