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Dietary nitrate

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https://www.readbyqxmd.com/read/29660828/storage-stability-of-dietary-nitrate-and-phenolic-compounds-in-beetroot-beta-vulgaris-and-arugula-eruca-sativa-juices
#1
Karen A Corleto, Jashbir Singh, G K Jayaprakasha, Bhimanagouda S Patil
Nitrate and polyphenols from the diet may enhance the production and bioavailability of nitric oxide, a radical signaling molecule critical for cardiovascular health. Understanding the stability of these bioactives in beetroot and arugula juices is important for their functions. In this study, the stability of nitrate and phenolics in beetroot and arugula juices was measured for 32 days at different temperatures (25, 4, -20, and -80 °C). The levels of nitrate were measured by reversed-phase HPLC and initial levels were found to be 4965...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29628462/-long-term-dietary-nitrite-and-nitrate-deficiency-causes-metabolic-syndrome-endothelial-dysfunction-and-cardiovascular-death-in-mice
#2
Mika Kina-Tanada, Mayuko Sakanashi, Akira Arasaki, Masato Tsutsui
Nitric oxide (NO) is synthesized not only from L-arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate. Green leafy vegetables are abundant in nitrate, however whether or not a deficiency in dietary nitrite/nitrate spontaneously causes disease remains to be clarified. In this study, we tested our hypothesis that long-term dietary nitrite/nitrate deficiency induces metabolic syndrome (MetS) in mice. To this end, we prepared a low nitrite/nitrate diet (LND) consisting of an amino acid-based low nitrite/nitrate chow in which the contents of L-arginine, fat, carbohydrates, protein, and energy were identical with a regular chow, and potable ultrapure water...
2018: Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
https://www.readbyqxmd.com/read/29625952/effects-of-dietary-inorganic-nitrate-supplementation-on-exercise-performance-in-patients-with-heart-failure-protocol-for-a-randomized-placebo-controlled-cross-over-trial
#3
Mary N Woessner, Itamar Levinger, Christopher Neil, Cassandra Smith, Jason D Allen
BACKGROUND: Chronic heart failure is characterized by an inability of the heart to pump enough blood to meet the demands of the body, resulting in the hallmark symptom of exercise intolerance. Chronic underperfusion of the peripheral tissues and impaired nitric oxide bioavailability have been implicated as contributors to the decrease in exercise capacity in these patients. nitric oxide bioavailability has been identified as an important mediator of exercise tolerance in healthy individuals, but there are limited studies examining the effects in patients with chronic heart failure...
April 6, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29606168/temperament-and-dominance-relate-to-feeding-behaviour-and-activity-in-beef-cattle-implications-for-performance-and-methane-emissions
#4
P Llonch, M Somarriba, C A Duthie, S Troy, R Roehe, J Rooke, M J Haskell, S P Turner
In beef cattle, feeding behaviour and activity are associated with feed efficiency and methane (CH4) emissions. This study aimed to understand the underlying traits responsible for the contribution of cattle behaviour to individual differences in feed efficiency, performance and CH4 emissions. A total of 84 steers (530±114 kg BW) of two different breeds (crossbreed Charolais and Luing) were used. The experiment was a 2×2×3 factorial design with breed, basal diets (concentrate v. mixed) and dietary treatments (no additive, calcium nitrate or rapeseed cake) as the main factors...
April 2, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29589768/ioc-consensus-statement-dietary-supplements-and-the-high-performance-athlete
#5
Ronald J Maughan, Louise M Burke, Jiri Dvorak, D Enette Larson-Meyer, Peter Peeling, Stuart M Phillips, Eric S Rawson, Neil P Walsh, Ina Garthe, Hans Geyer, Romain Meeusen, Luc van Loon, Susan M Shirreffs, Lawrence L Spriet, Mark Stuart, Alan Vernec, Kevin Currell, Vidya M Ali, Richard G M Budgett, Arne Ljungqvist, Margo Mountjoy, Yannis Pitsiladis, Torbjørn Soligard, Uğur Erdener, Lars Engebretsen
Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition program. Nonetheless, supplement use is widespread at all levels of sport. Products described as supplements target different issues, including the management of micronutrient deficiencies, supply of convenient forms of energy and macronutrients, and provision of direct benefits to performance or indirect benefits such as supporting intense training regimens...
March 28, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29588164/nitrated-fatty-acids-in-cardiovascular-diseases
#6
REVIEW
Martin Mollenhauer, Dennis Mehrkens, Volker Rudolph
Cardiovascular disease (CVD) is the leading cause of death and accounts for one third of disease-related mortality worldwide. Dysregulated redox mechanisms, in particular the formation of reactive oxygen species (ROS) play a pivotal pathogenetic role in CVD. Nitro-fatty acids (NO2 -FAs) are electrophilic molecules which have a NO2 -group bound to one of their olefinic carbons. They are endogenously formed by the reaction of reactive nitrogen species with unsaturated fatty acids. Basal levels of NO2 -FAs are in the low nanomolar range and higher concentrations can be encountered under acidic (stomach) and inflammatory (e...
March 24, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29576063/review-on-the-significance-of-chlorine-for-crop-yield-and-quality
#7
REVIEW
Christoph-Martin Geilfus
The chloride concentration in the plant determines yield and quality formation for two reasons. First, chlorine is a mineral nutrient and deficiencies thereof induce metabolic problems that interfere with growth. However, due to low requirement of most crops, deficiency of chloride hardly appears in the field. Second, excess of chloride, an event that occurs under chloride-salinity, results in severe physiological dysfunctions impairing both quality and yield formation. The chloride ion can effect quality of plant-based products by conferring a salty taste that decreases market appeal of e...
May 2018: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/29559721/increasing-vegetable-intake-to-obtain-the-health-promoting-and-ergogenic-effects-of-dietary-nitrate
#8
REVIEW
Cindy M T Van der Avoort, Luc J C Van Loon, Maria T E Hopman, Lex B Verdijk
Increased consumption of dietary nitrate increases plasma nitrate and nitrite concentrations, and has been shown to elicit cardio-protective effects and improve exercise performance. Nitrate consumption in the habitual diet is mainly dependent on nitrate-rich vegetables, such as green leafy and root vegetables, with total vegetable consumption accounting for approximately 50-85% of our daily nitrate intake. Whereas 'supplementation' with dietary nitrate in research studies has mainly been accomplished through the use of (concentrated) nitrate-rich beetroot juice, dietary strategies focusing on increased intake of nitrate-rich vegetables may represent a similarly effective alternative for increasing dietary nitrate intake and, as such, obtaining the associated cardiovascular health and ergogenic benefits...
March 20, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29553034/nitrate-supplementation-improves-physical-performance-specifically-in-non-athletes-during-prolonged-open-ended-tests-a-systematic-review-and-meta-analysis
#9
Helton O Campos, Lucas R Drummond, Quezia T Rodrigues, Frederico S M Machado, Washington Pires, Samuel P Wanner, Cândido C Coimbra
Nitrate (NO3 -) is an ergogenic nutritional supplement that is widely used to improve physical performance. However, the effectiveness of NO3 - supplementation has not been systematically investigated in individuals with different physical fitness levels. The present study analysed whether different fitness levels (non-athletes v. athletes or classification of performance levels), duration of the test used to measure performance (short v. long duration) and the test protocol (time trials v. open-ended tests v...
March 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29553033/dietary-nitrate-lowers-ambulatory-blood-pressure-in-treated-uncontrolled-hypertension-a-7-d-double-blind-randomised-placebo-controlled-cross-over-trial
#10
Conor P Kerley, Eamon Dolan, Philip E James, Liam Cormican
Dietary nitrate has been shown to increase nitrate/nitrite levels and decrease blood pressure (BP) in multiple populations. There are few reports among hypertensives and these reports have provided conflicting evidence. We aimed to assess the effect of daily nitrate compared with placebo in subjects with uncontrolled hypertension (HTN). On day 0, hypertensives wore an ambulatory BP monitor (ABPM) for 24 h and blood was taken. Subjects were then randomised to 7-d nitrate-rich beetroot juice (NO3 -) (12·9 mmol nitrate) followed by 7-d nitrate-depleted beetroot juice (0·5 mmol nitrate) or vice versa...
March 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29550903/functional-nitric-oxide-nutrition-to-combat-cardiovascular-disease
#11
REVIEW
Nathan S Bryan
PURPOSE OF REVIEW: To reveal the mechanisms of nitric oxide (NO) production in humans and how lifestyle, drug therapy, and hygienic practices can decrease NO production. Furthermore, to show how functional nitric oxide nutrition can overcome these limitations to restore endogenous NO production and combat cardiovascular disease. RECENT FINDINGS: Research over the past decade has revealed that inorganic nitrate and nitrite found naturally in green leafy vegetables and other vegetables such as beets can provide the human body with a source of bioactive nitric oxide...
March 17, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29550811/gum-acacia-improves-renal-function-and-ameliorates-systemic-inflammation-oxidative-and-nitrosative-stress-in-streptozotocin-induced-diabetes-in-rats-with-adenine-induced-chronic-kidney-disease
#12
Mohammed Al Za'abi, Suhail Al Salam, Yousuf Al Suleimani, Priyadarsini Manoj, Abderrahim Nemmar, Badreldin H Ali
BACKGROUND/AIMS: The effect of treatment with gum acacia (GA), a prebiotic shown previously to ameliorate chronic kidney disease (CKD), in diabetic and non - diabetic rats with adenine - induced CKD has been investigated using several conventional and novel physiological, biochemical, and histopathological parameters. METHODS: Diabetes mellitus was induced in rats by a single injection of streptozotocin (STZ). Diabetic and non - diabetic rats were randomly divided into several groups, and given either normal food or food mixed with adenine (0...
March 13, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29550328/salivary-nitrite-production-is-elevated-in-individuals-with-a-higher-abundance-of-oral-nitrate-reducing-bacteria
#13
Mia C Burleigh, Luke Liddle, Chris Monaghan, David J Muggeridge, Nicholas Sculthorpe, John P Butcher, Fiona L Henriquez, Jason D Allen, Chris Easton
Nitric oxide (NO) can be generated endogenously via NO synthases or via the diet following the action of symbiotic nitrate-reducing bacteria in the oral cavity. Given the important role of NO in smooth muscle control there is an intriguing suggestion that cardiovascular homeostasis may be intertwined with the presence of these bacteria. Here, we measured the abundance of nitrate-reducing bacteria in the oral cavity of 25 healthy humans using 16S rRNA sequencing and observed, for 3.5hours, the physiological responses to dietary nitrate ingestion via measurement of blood pressure, and salivary and plasma NO metabolites...
March 14, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29549005/influence-of-dietary-nitrate-supplementation-on-lung-function-and-exercise-gas-exchange-in-copd-patients
#14
Mehrdad Behnia, Courtney M Wheatley, Alberto Avolio, Bruce D Johnson
BACKGROUND: During exercise as pulmonary blood flow rises, pulmonary capillary blood volume increases and gas exchange surface area expands through distention and recruitment. We have previously demonstrated that pulmonary capillary recruitment is limited in COPD patients with poorer exercise tolerance. Hypoxia and endothelial dysfunction lead to pulmonary vascular dysregulation possibly in part related to nitric oxide related pathways. PURPOSE: To determine if increasing dietary nitrate might influence lung surface area for gas exchange and subsequently impact exercise performance...
March 13, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29547495/dietary-nitrate-and-muscle-function-in-humans-acute-versus-chronic-mechanisms
#15
Andrew R Coggan
No abstract text is available yet for this article.
April 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29544657/functional-foods-for-augmenting-nitric-oxide-activity-and-reducing-the-risk-for-salt-induced-hypertension-and-cardiovascular-disease-in-japan
#16
REVIEW
Theodore W Kurtz, Stephen E DiCarlo, Michal Pravenec, R Curtis Morris
High salt intake is one of the major dietary determinants of hypertension and cardiovascular disease in Japan and throughout the world. Although dietary salt restriction may be of clinical benefit in salt-sensitive individuals, many individuals may not wish, or be able to, reduce their intake of salt. Thus, identification of functional foods that can help protect against mechanistic abnormalities mediating salt-induced hypertension is an issue of considerable medical and scientific interest. According to the "vasodysfunction" theory of salt-induced hypertension, the hemodynamic abnormality initiating salt-induced increases in blood pressure usually involves subnormal vasodilation and abnormally increased vascular resistance in response to increased salt intake...
March 12, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29540367/ioc-consensus-statement-dietary-supplements-and-the-high-performance-athlete
#17
Ronald J Maughan, Louise M Burke, Jiri Dvorak, D Enette Larson-Meyer, Peter Peeling, Stuart M Phillips, Eric S Rawson, Neil P Walsh, Ina Garthe, Hans Geyer, Romain Meeusen, Lucas J C van Loon, Susan M Shirreffs, Lawrence L Spriet, Mark Stuart, Alan Vernec, Kevin Currell, Vidya M Ali, Richard Gm Budgett, Arne Ljungqvist, Margo Mountjoy, Yannis P Pitsiladis, Torbjørn Soligard, Uğur Erdener, Lars Engebretsen
Nutrition usually makes a small but potentially valuable contribution to successful performance in elite athletes, and dietary supplements can make a minor contribution to this nutrition programme. Nonetheless, supplement use is widespread at all levels of sport. Products described as supplements target different issues, including (1) the management of micronutrient deficiencies, (2) supply of convenient forms of energy and macronutrients, and (3) provision of direct benefits to performance or (4) indirect benefits such as supporting intense training regimens...
April 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29529987/potential-benefits-of-dietary-nitrate-ingestion-in-healthy-and-clinical-populations-a-brief-review
#18
Sinead T J Mcdonagh, Lee J Wylie, Christopher Thompson, Anni Vanhatalo, Andrew M Jones
This article provides an overview of the current literature relating to the efficacy of dietary nitrate (NO3 - ) ingestion in altering aspects of cardiovascular and metabolic health and exercise capacity in healthy and diseased individuals. The consumption of NO3 - -rich vegetables, such as spinach and beetroot, have been variously shown to promote nitric oxide bioavailability, reduce systemic blood pressure, enhance tissue blood flow, modulate muscle O2 utilisation and improve exercise tolerance both in normoxia and in hypoxia, as is commonly observed in a number of disease states...
March 13, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29523272/nitrate-rich-dietary-supplementation-during-pregnancy-the-pros-and-cons
#19
Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi, Asghar Ghasemi
Inorganic nitrate (NO3 ) due to its potential endogenous conversion to nitric oxide (NO), is suggested as a compensatory fuel for disrupted NO pathways in the case of pathological stats during pregnancy. Dietary NO3 -rich supplement in the NO-deficient pregnant women is now suggested as a more appealing choice with fewer off-target effects which can attenuate hypertension and preeclampsia, improve placental blood flow and subsequently enhance maternal and neonatal health. There is also an increasing public interest and common health claims regarding beneficial effects of NO3 -rich dietary supplements like beetroot byproducts in pregnant women...
January 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29522355/eight-weeks-of-nitrate-supplementation-improves-blood-flow-and-reduces-the-exaggerated-pressor-response-during-forearm-exercise-in-peripheral-arterial-disease
#20
Nicholas T Kruse, Kenichi Ueda, William E Hughes, Darren P Casey
Peripheral arterial disease (PAD) is characterized by a reduced blood flow (BF) and elevated blood pressure (pressor) response during lower extremity exercise. Although PAD is evident in the upper extremities no studies have determined BF and pressor responses during upper extremity exercise in PAD. Emerging evidence suggests that inorganic nitrate (NO3 ) supplementation may serve as an alternative dietary strategy to boost nitric oxide bioavailability, improving exercising BF and pressor responses during exercise...
March 9, 2018: American Journal of Physiology. Heart and Circulatory Physiology
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