keyword
https://read.qxmd.com/read/38651546/risk-factors-for-inadequate-bowel-preparation-before-colonoscopy-a-meta-analysis
#1
REVIEW
Lina Feng, Jialun Guan, Ruonan Dong, Kai Zhao, Mingyu Zhang, Suhong Xia, Yu Zhang, Liping Chen, Fang Xiao, Jiazhi Liao
OBJECTIVE: This meta-analysis aimed to comprehensively explore the risk factors for inadequate bowel preparation (IBP). METHODS: We searched the Embase, PubMed, Web of Science, and The Cochrane Library databases up to August 24, 2023, to identify observational studies and randomized controlled trials (RCTs) that examined risk factors for IBP. A random effects model was used to pool the adjusted odds ratios and 95% confidence intervals. RESULTS: A total of 125 studies (91 observational studies, 34 RCTs) were included...
April 23, 2024: Journal of Evidence-based Medicine
https://read.qxmd.com/read/38623288/green-and-efficient-magnetic-micro-solid-phase-extraction-utilizing-tea-waste-impregnated-with-magnetic-nanoparticles-for-the-analysis-of-ibuprofen-in-water-samples-by-using-uv-vis-spectrophotometry
#2
JOURNAL ARTICLE
Yagulan Muniandy, Sharifah Mohamad, Muggundha Raoov
A green method based on magnetic micro-solid phase extraction (MNP-TW-μ-SPE) of tea waste impregnated with magnetic nanoparticles (MNP-TW) was developed for the extraction of ibuprofen (IBP) in water samples prior to UV-Vis spectrophotometric analysis. Experimenting parameters that affect the extraction efficiency of IBP, such as pH of the sample solution, sorbent dosage, extraction time, ionic strength, volume of the sample, type of desorption solvent, desorption time, and desorption volume, were studied and optimized in detail...
April 10, 2024: RSC Advances
https://read.qxmd.com/read/38621686/-diagnosis-and-classification-of-axial-spondyloarthritis-axspa-the-current-status
#3
JOURNAL ARTICLE
Jürgen Braun, Denis Poddubnyy
Axial spondyloarthritis (axSpA) is an inflammatory rheumatic disease typically characterized by inflammatory back pain (IBP). The term axSpA has largely replaced the long-used term ankylosing spondylitis (AS). IBP is caused by inflammation in the axial skeleton, with the sacroiliac joints (SIJ) being particularly frequently affected initially. The spine is usually added in later stages, which is then increasingly characterized structurally by the formation of new bone. The overall concept of spondyloarthritis includes other disease manifestations such as uveitis, psoriasis and colitis and comorbidities such as cardiovascular disease and osteoporosis...
April 2024: Deutsche Medizinische Wochenschrift
https://read.qxmd.com/read/38619594/repeated-dose-toxicity-and-toxicokinetic-study-of-isobutylparaben-in-rats-subcutaneously-treated-for-13%C3%A2-weeks
#4
JOURNAL ARTICLE
Jung Dae Lee, Jin-Sook Bae, Hyang Yeon Kim, Si-Whan Song, Jong-Choon Kim, Byung-Mu Lee, Kyu-Bong Kim
Parabens have historically served as antimicrobial preservatives in a range of consumables such as food, beverages, medications, and personal care products due to their broad-spectrum antibacterial and antifungal properties. Traditionally, these compounds were believed to exhibit low toxicity, causing minimal irritation, and possessing limited sensitization potential. However, recent evidence suggests that parabens might function as endocrine-disrupting chemicals (EDCs). Consequently, extensive research is underway to elucidate potential human health implications arising from exposure to these substances...
April 15, 2024: Archives of Toxicology
https://read.qxmd.com/read/38618898/rapid-identification-of-potential-nonsteroidal-anti-inflammatory-drug-overdose-induced-liver-toxicity-and-prediction-of-follow-up-exposure-integrating-bioanalytical-and-population-pharmacokinetic-assay
#5
JOURNAL ARTICLE
Sufeng Zhou, Tangping Zhao, Jie Wang, Luming Wang, Zimo Zhang, Jinying Zhu, Yuqing Zhao, Ying Zhu, Hao Sun, Feng Shao
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most frequently used drugs that can cause liver toxicity. The aim of this study was to integrate bioanalytical and population pharmacokinetic (PopPK) assay to rapidly screen and quantify the concentrations of NSAIDs in plasma and monitor clinical safety. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous quantification of acetaminophen (APAP), flurbiprofen (FLB), aspirin (ASP), and ibuprofen (IBP), four commonly used NSAIDs...
April 15, 2024: Biomedical Chromatography: BMC
https://read.qxmd.com/read/38618560/assessing-the-quality-and-reliability-of-youtube-videos-as-a-source-of-information-on-inflammatory-back-pain
#6
JOURNAL ARTICLE
Mete Kara, Erkan Ozduran, Müge Mercan Kara, Volkan Hanci, Yüksel Erkin
BACKGROUND: Inflammatory back pain is a chronic condition with localized pain, particularly in the axial spine and sacroiliac joints, that is associated with morning stiffness and improves with exercise. YouTube is the second most frequently used social media platform for accessing health information. This study sought to investigate the quality and reliability of YouTube videos on inflammatory back pain (IBP). METHODS: The study design was planned as cross-sectional...
2024: PeerJ
https://read.qxmd.com/read/38609245/novel-foods-old-issues-metabarcoding-revealed-mislabeling-in-insect-based-products-sold-by-e-commerce-on-the-eu-market
#7
JOURNAL ARTICLE
Alice Giusti, Gabriele Spatola, Simone Mancini, Roberta Nuvoloni, Andrea Armani
Insects intended for human consumption are considered Novel Foods according to EU legislation. marketed in form of powders, bars, snacks are increasingly available on the EU market, especially on e-commerce. The commercial form and the way of distribution make IBPs particularly prone to mislabeling. Literature concerning the mislabeling occurrence in IBPs is extremely scarce. In this study, 46 processed IBPs were collected on nine EU e-commerce platforms (e-CO) to be authenticated by metabarcoding. A 200 bp region from 16S rRNA gene was used as molecular target...
May 2024: Food Research International
https://read.qxmd.com/read/38574292/role-for-carboxylic-acid-moiety-in-nsaids-favoring-the-binding-at-site-ii-of-bovine-serum-albumin
#8
JOURNAL ARTICLE
Luiza de Carvalho Bertozo, Hugo Cesar Tadeu, Anila Sebastian, Martyna Maszota-Zieleniak, Sergey A Samsonov, Valdecir Farias Ximenes
The molecular structures of nonsteroidal anti-inflammatory drugs (NSAIDs) vary, but most contain a carboxylic acid functional group (RCOOH). This functional group is known to be related to the mechanism of cyclooxygenase inhibition and also causes side effects, such as gastrointestinal bleeding. This study proposes a new role for RCOOH in NSAIDs: facilitating the interaction at the binding site II of serum albumins. We used bovine serum albumin (BSA) as a model to investigate the interactions with ligands at site II...
April 4, 2024: Molecular Pharmaceutics
https://read.qxmd.com/read/38558651/a-survey-exploring-inflammatory-back-pain-in-patients-with-inflammatory-bowel-disease
#9
JOURNAL ARTICLE
Onkarpreet K Jassel, Hasan Tahir, Sian Bamford, Paolo Giuffrida
Background Diagnostic delay of axial spondyloarthritis (axSpA) is a widely recognized issue worldwide, providing a great burden for patients with this disease. AxSpA is present in a significant proportion of patients with inflammatory bowel disease (IBD). This UK study primarily aims to identify the presence of inflammatory back pain (IBP) in patients attending IBD clinic. Further aims of this study include investigating if participants had received further referrals and diagnoses for their IBP and considering factors contributing to diagnostic delay...
February 2024: Curēus
https://read.qxmd.com/read/38527127/extended-temperature-range-of-the-ice-binding-protein-activity
#10
JOURNAL ARTICLE
Vera Sirotinskaya, Maya Bar Dolev, Victor Yashunsky, Liat Bahari, Ido Braslavsky
Ice-binding proteins (IBPs) are expressed in various organisms for several functions, such as protecting them from freezing and freeze injuries. Via adsorption on ice surfaces, IBPs depress ice growth and recrystallization and affect nucleation and ice shaping. IBPs have shown promise in mitigating ice growth under moderate supercooling conditions, but their functionality under cryogenic conditions has been less explored. In this study, we investigate the impact of two types of antifreeze proteins (AFPs): type III AFP from fish and a hyperactive AFP from an insect, the Tenebrio molitor AFP, in vitrified dimethylsulfoxide (DMSO) solutions...
March 25, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38508562/polyethyleneimine-functionalized-magnetic-sugarcane-bagasse-cellulose-film-for-the-efficient-adsorption-of-ibuprofen
#11
JOURNAL ARTICLE
Yang Liu, Yan-Shu Xiong, Ming-Xing Li, Wen Li, Kai Li
Polyethyleneimine-modified magnetic sugarcane bagasse cellulose film (P-SBC/Fe3 O4 film) was simply fabricated for the removal of ibuprofen (IBP), a typical emerging organic contaminant. The P-SBC/Fe3 O4 film exhibited an equilibrium adsorption amount of 370.52 mg/g for IBP and a corresponding removal efficiency of 92.63 % under following adsorption conditions: 318 K, pH 4, and 0.25 mg/mL dosage. Thermodynamic studies indicated that adsorption of IBP on the P-SBC/Fe3 O4 film was spontaneous (∆G < 0) and endothermic (∆H > 0)...
March 18, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38506687/balloon-pressure-and-clinical-effectiveness-of-percutaneous-microballoon-compression-in-the-treatment-of-primary-trigeminal-neuralgia
#12
JOURNAL ARTICLE
Yingqian Peng, Cong Zou, Yonglin Li, Qing Li, Hui Long, Wuzhou Yang, Zhenping Xiao, Liping Jiang, Wei Gao, Yunwu He
BACKGROUND: Primary trigeminal neuralgia (PTN) is a type of chronic neuropathic pain disorder caused by neurovascular compression. Percutaneous balloon compression (PBC) is a widely used method for the treatment of PTN. OBJECTIVES: To examine the correlation of balloon pressure (BP) during percutaneous microballoon compression (PBC) with postoperative pain relief and complications in the treatment of primary trigeminal neuralgia (PTN). STUDY DESIGN: Forty-five patients diagnosed with PTN and treated with PBC were recruited...
March 2024: Pain Physician
https://read.qxmd.com/read/38503051/doppler-ultrasound-is-more-accurate-than-pulse-oximeter-plethysmography-in-the-measurement-of-systolic-arterial-pressure-from-the-median-caudal-artery-in-anesthetized-dogs
#13
JOURNAL ARTICLE
John H Whittaker, Nathaniel Kapaldo, Eduarda M Bortoluzzi, David C Rankin
OBJECTIVE: To compare the accuracy of doppler ultrasound (DOP) and pulse oximeter plethysmography (POP) in the measurement of systolic arterial pressure (SAP) to invasive blood pressure (IBP) in anesthetized dogs. ANIMALS: 40 client-owned healthy dogs > 10 kg. METHODS: Dogs were anesthetized for surgical procedures in dorsal recumbency. Invasive blood pressure was measured from a dorsal pedal artery. DOP and POP device probes were placed over the median caudal artery with a flow-occluding cuff for noninvasive blood pressure measurement...
March 23, 2024: American Journal of Veterinary Research
https://read.qxmd.com/read/38479110/clinical-and-imaging-outcomes-of-different-phenotypes-of-axial-spondyloarthritis-5-year-analysis-of-the-desir-cohort
#14
JOURNAL ARTICLE
Alexandre Sepriano, Sofia Ramiro, Désirée van der Heijde, Anna Moltó, Cécile Gaujoux-Viala, Maxime Dougados, Robert Landewé
OBJECTIVES: To compare the long-term outcomes of three phenotypes of axial SpA (axSpA). METHODS: Patients with a clinical diagnosis of axSpA from the DESIR cohort were grouped into three phenotypes at baseline: 'Pure axSpA' ('Axial'), 'axSpA with peripheral signs' ('IBP+Peripheral') and 'axSpA at risk' ('At risk') by latent class analysis. Clinical and imaging data were collected up to 5 years. Clinical outcomes, measured in each visit, included disability (BASFI) and quality of life (QoL; SF36)...
March 2, 2024: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/38452678/insight-into-roles-of-carbon-anodes-for-removal-of-refractory-organic-contaminants-in-electro-peroxone-system-mechanism-performance-and-stability
#15
JOURNAL ARTICLE
Zekun Dong, Jie Yao, Zhihui Hu, Jiao Yang, Yan Zhang
Electro-peroxone (EP) is a novel technique for the removal of refractory organic contaminants (ROCs), while the role of anode in this system is neglected. In this work, the EP system with graphite felt anode (EP-GF) and activated carbon fiber anode (EP-ACF) was developed to enhance ibuprofen (IBP) removal. The results showed that 91.2% and 98.6% of IBP was removed within 20 min in EP-GF and EP-ACF, respectively. Hydroxy radical (O⋅H) was identified as the dominant reactive species, contributing 80...
March 5, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38399241/controlling-the-quality-of-nanodrugs-according-to-their-new-property-radiothermal-emission
#16
JOURNAL ARTICLE
Gleb V Petrov, Daria A Galkina, Alena M Koldina, Tatiana V Grebennikova, Olesya V Eliseeva, Yana Yu Chernoryzh, Varvara V Lebedeva, Anton V Syroeshkin
Previous studies have shown that complexly shaped nanoparticles (NPs) have their intrinsic radiothermal emission in the millimeter range. This article presents a method for controlling the quality of nanodrugs-immunobiological preparations (IBPs)-based on the detection of their intrinsic radiothermal emissions. The emissivity of interferon (IFN) medicals, determined without opening the primary package, is as follows (µW/m2 ): IFN-α2b-80 ± 9 (105 IU per package), IFN-β1a-40 ± 5 (24 × 106 IU per package), IFN-γ-30 ± 4 (105 IU per package)...
January 26, 2024: Pharmaceutics
https://read.qxmd.com/read/38368367/enhancing-tube-feeding-method-for-neurosurgery-the-application-of-improved-picc-technique
#17
JOURNAL ARTICLE
Huiwen Wu, Yuru Qiu, Yucui Wang, Jiarong Li, Yihong Qiu
BACKGROUND AND PURPOSE: Peripherally inserted central catheter (PICC) used in neurosurgical patients requires changes in patients' head positions. However, such changes can worsen pressure on the brain tissue, lead to sudden acute brain herniation and respiratory arrest, resulting in a higher chance of patient death. This paper addresses the aforementioned problems by introducing a new PICC catheterization method. METHOD: In a retrospective study, the records of patients with PICC from April 2020 to April 2023 were reviewed, and they were divided into three groups based on the methods employed...
February 17, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38356207/enantioselective-separation-and-determination-of-ibuprofen-stereoselective-pharmacokinetics-pharmacodynamics-and-analytical-methods
#18
REVIEW
Vinod Kumar Vashistha, Tarun Kumar, Suman Yadav, Dipak Kumar Das
Ibuprofen (IBP), the 29th most prescribed drug in the United States in 2019, is a widely used nonsteroidal anti-inflammatory drug (NSAID) comprising two enantiomers, (R)-IBP and (S)-IBP, collectively known as (RS)-IBP. This critical review examines analytical techniques for the enantioselective separation and determination of IBP enantiomers, crucial for pharmaceutical and clinical applications. The review focuses on state-of-the-art methods, including chromatographic techniques including high-performance liquid chromatography, gas chromatography, liquid chromatography-tandem mass spectrometry, and some other techniques...
February 2024: Chirality
https://read.qxmd.com/read/38333437/a-patient-survey-exploring-the-burden-of-inflammatory-back-pain-in-patients-with-known-psoriasis
#19
JOURNAL ARTICLE
Sophia Watts, Lydia G Nagib, Sian Bamford, Adil Sheraz, Hasan Tahir
Background In the United Kingdom, diagnostic delay remains a challenge in axial spondyloarthritis (axSpA). Psoriasis is a frequently identified extra-musculoskeletal manifestation associated with axSpA. In this study, we aimed to determine the prevalence of inflammatory back pain (IBP) in psoriasis patients at a specialized psoriasis dermatology clinic in a London NHS Trust. Our primary goal was to identify psoriasis patients with IBP who were not referred to a rheumatologist, potentially leading to axSpA diagnostic delays...
January 2024: Curēus
https://read.qxmd.com/read/38331970/engineered-ice-binding-protein-ffibp-shows-increased-stability-and-resistance-to-thermal-and-chemical-denaturation-compared-to-the-wildtype
#20
JOURNAL ARTICLE
Yewon Nam, Dieu Linh Nguyen, Trang Hoang, Bogeun Kim, Jun Hyuck Lee, Hackwon Do
Many polar organisms produce antifreeze proteins (AFPs) and ice-binding proteins (IBPs) to protect themselves from ice formation. As IBPs protect cells and organisms, the potential of IBPs as natural or biological cryoprotective agents (CPAs) for the cryopreservation of animal cells, such as oocytes and sperm, has been explored to increase the recovery rate after freezing-thawing. However, only a few IBPs have shown success in cryopreservation, possibly because of the presence of protein denaturants, such as dimethyl sulfoxide, alcohols, or ethylene glycol, in freezing buffer conditions, rendering the IBPs inactive...
February 8, 2024: Scientific Reports
keyword
keyword
93452
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.