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https://www.readbyqxmd.com/read/28318231/paraben-concentrations-in-maternal-urine-and-breast-milk-and-its-association-with-personal-care-product-use
#1
Mandy Fisher, Susan MacPherson, Joseph M Braun, Russ Hauser, Mark Walker, Mark Feeley, Ranjeeta Mallick, René Bérubé, Tye E Arbuckle
Parabens are broad-spectrum antimicrobial preservatives and fragrances used in a wide range of personal care products, pharmaceuticals, and food providing the opportunity for people to be exposed on a daily basis. In 2009-2010, 80 pregnant women from Ottawa Canada participated in the Plastics and Personal-Care Product Use in Pregnancy (P4) Study. A subset of women (n = 31) who provided multiple spot urine samples (n = 542) collected over two 24-h periods had their samples analyzed for methylparaben (MP), n-propylparaben (PP), ethylparaben (EP), butylparaben (BP), isobutylparaben (IBP), and benzylparaben (BzP)...
March 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28298771/attenuation-of-hemodynamic-response-to-skull-pin-head-holder-insertion-intravenous-clonidine-versus-intravenous-lignocaine-infusion
#2
Nethra H Nanjundaswamy, Vinay Marulasiddappa
BACKGROUND: Insertion of skull pin induces a significant increase in heart rate (HR), blood pressure (BP) and intracranial pressure. Alpha 2 agonist clonidine and intravenous (i.v.) lignocaine are effective in attenuating stress response. Local infiltration of pin site and scalp block with lignocaine are commonly used techniques for prevention of hemodynamic response to skull pin insertion. We compared the effectiveness of i.v. clonidine infusion and i.v. lignocaine infusion in suppressing the hemodynamic response to skull pin head holder insertion...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28293822/ibuprofen-removal-by-heterogeneous-photocatalysis-and-ecotoxicological-evaluation-of-the-treated-solutions
#3
EDITORIAL
João P Candido, Sandro J Andrade, Ana L Fonseca, Flávio S Silva, Milady R A Silva, Márcia M Kondo
Emerging contaminants including pharmaceuticals are a class of compounds that are causing great concern due to several environmental problems. Conventional water and wastewater treatments do not achieve high removal efficiencies for many of these drugs. Therefore, the present work investigated the removal of ibuprofen (IBP) by heterogeneous photocatalysis using TiO2 irradiated with artificial UV light or solar radiation. The treated solutions were tested against Daphnia similis and Raphidocelis subcapitata, which are species commonly used as bioindicators of environmental conditions...
March 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28243962/adsorption-behavior-and-mechanism-of-ibuprofen-onto-biocl-microspheres-with-exposed-001-facets
#4
Jian Li, Shiye Sun, Rong Chen, Tuqiao Zhang, Bangxing Ren, Dionysios D Dionysiou, Zhejian Wu, Xiaowei Liu, Miaomiao Ye
BiOCl microspheres with exposed {001} facets have been synthesized through a simple solvothermal method. The adsorption and photocatalytic activities of BiOCl microspheres were evaluated by removal of ibuprofen (IBP) as the model reaction. Parameters including IBP concentration, BiOCl dosage, and inorganic ions were investigated to reveal the role of adsorption in BiOCl-based photocatalysis. We found that the high IBP removal rate by BiOCl is not due to photocatalytic oxidation but to surface adsorption. The combination of ICP/MS, IC, XPS, and FT-IR results directly proved that anion exchange between dissociated IBP and Cl accompanied by the formation of surface complex (O-Bi-OOC-C12H17) onto the BiOCl surface is the main adsorption mechanism...
February 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28236581/single-simultaneous-and-sequential-applications-of-ultrasonic-frequencies-for-the-elimination-of-ibuprofen-in-water
#5
Asu Ziylan-Yavas, Nilsun H Ince
The study is about the assessment of single and multi-frequency operations for the overall degradation of a widely consumed analgesic pharmaceutical-ibuprofen (IBP). The selected frequencies were in the range of 20-1130kHz emissions coming from probes, baths and piezo-electric transducers attached to plate-type devices. Multi-frequency operations were applied either simultaneously as "duals", or sequentially at fixed time intervals; and the total reaction time in all operations was 30-min. The work also covers evaluation of the effect of zero-valent iron (ZVI) on the efficiency of the degradation process and the performance of the reaction systems...
January 26, 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28214597/classification-criteria-versus-physician-s-opinion-for-considering-a-patient-with-inflammatory-back-pain-as-suffering-from-spondyloarthritis
#6
Pierre Gazeau, Divi Cornec, Marie Agnes Timsit, Maxime Dougados, Alain Saraux
OBJECTIVE: To assess agreement among methods for classifying patients with inflammatory back pain [IBP] after a 2-year follow up. METHODS: Patients with IBP in the French nationwide, longitudinal, prospective cohort DESIR were classified after 2 years based on imaging findings, rheumatologist's confidence in a diagnosis of spondyloarthritis, three classification criteria sets [axial Assessment of Spondyloarthritis international Society (ASAS), European Spondylarthropathy Study Group (ESSG), and Amor] and treatment [TNFα antagonists]...
February 15, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28189026/mass-spectrometry-based-in%C3%A2-vitro-assay-investigations-on-the-transformation-of-pharmaceutical-compounds-by-oxidative-enzymes
#7
Lara F Stadlmair, Thomas Letzel, Jörg E Drewes, Johanna Graßmann
The ubiquitous presence of trace organic chemicals in wastewater and surface water leads to a growing demand for novel removal technologies. The use of isolated enzymes has been shown to possess the capability for a targeted application but requires a clearer mechanistic understanding. In this study, the potential of peroxidase from horseradish (HRP) and laccase from Pleurotus ostreatus (LccPO) to transform selected trace organic chemicals was studied using mass spectrometry (MS)-based in vitro enzyme assays...
May 2017: Chemosphere
https://www.readbyqxmd.com/read/28137767/smprot-a-database-of-small-proteins-encoded-by-annotated-coding-and-non-coding-rna-loci
#8
Yajing Hao, Lili Zhang, Yiwei Niu, Tanxi Cai, Jianjun Luo, Shunmin He, Bao Zhang, Dejiu Zhang, Yan Qin, Fuquan Yang, Runsheng Chen
Small proteins is the general term for proteins with length shorter than 100 amino acids. Identification and functional studies of small proteins have advanced rapidly in recent years, and several studies have shown that small proteins play important roles in diverse functions including development, muscle contraction and DNA repair. Identification and characterization of previously unrecognized small proteins may contribute in important ways to cell biology and human health. Current databases are generally somewhat deficient in that they have either not collected small proteins systematically, or contain only predictions of small proteins in a limited number of tissues and species...
January 29, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28129460/diagnostic-value-and-validity-of-early-spondyloarthritis-features-results-from-the-esperanza-cohort
#9
Beatriz E Joven, Victoria Navarro-Compán, Jose Rosas, Pilar Fernandez Dapica, Pedro Zarco, Eugenio De Miguel
OBJECTIVE: To evaluate the validity of different spondyloarthritis (SpA) features included in the Berlin diagnostic algorithm and the ASAS classification criteria in an early cohort. PATIENTS AND METHODS: This was a longitudinal multicentre study including patients with suspected SpA from the ESPeranza cohort. Subjects were ≤45 years old and SpA symptom duration was 3-24 months. Patients with axial symptoms were selected and categorized according to diagnosis (yes/no) of axial SpA (axSpA)...
January 27, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28101901/cyto-genotoxicity-and-oxidative-stress-in-common-carp-cyprinus-carpio-exposed-to-a-mixture-of-ibuprofen-and-diclofenac
#10
Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván, Marcela Galar-Martínez, Esmeralda Michelle Sánchez-Ocampo, Nely SanJuan-Reyes, Mariana Ortíz-Reynoso, Octavio Dublán-García
Thirty million people worldwide consume each day nonsteroidal anti-inflammatory drugs (NSAIDs), a heterogeneous group of pharmaceuticals used for its analgesic, antipyretic, and anti-inflammatory properties. Recent studies report high NSAID concentrations in wastewater treatment plant effluents, in surface, ground, and drinking water, and in sediments. NSAIDs are also known to induce toxicity on aquatic organisms. However, toxicity in natural ecosystems is not usually the result of exposure to a single substance but to a mixture of toxic agents, yet only a few studies have evaluated the toxicity of mixtures...
January 19, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28063066/high-prevalence-of-undiagnosed-axial-spondyloarthritis-in-patients-with-chronic-low-back-pain-consulting-non-rheumatologist-specialists-in-belgium-suspect-study
#11
Laure Tant, Nadine Delmotte, Maria Van den Enden, Valerie Gangji, Herman Mielants
INTRODUCTION: Diagnosis of axial spondyloarthritis (SpA) can be delayed for several years mainly because of low awareness of axial SpA among non-rheumatologists who are the first interlocutors of potential SpA patients. One strategy to decrease the delay between appearance of first symptoms and diagnosis of axial SpA and to allow early management of the disease is to provide the non-rheumatologists with tools to identify patients requiring prompt referral to rheumatologists. This study was designed to evaluate in a real-world setting whether screening patients with chronic low back pain who consult physical medicine and rehabilitation (PMR) physicians, orthopedists, and ophthalmologists is useful in detecting axial SpA...
January 6, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28038742/ibuprofen-loaded-pva-chitosan-membranes-a-highly-efficient-strategy-towards-an-improved-skin-wound-healing
#12
Patrícia I Morgado, Sónia P Miguel, Ilídio J Correia, Ana Aguiar-Ricardo
During wound healing, an early inflammation can cause an increase of the wound size and the healing process can be considerably belated if a disproportionate inflammatory response occurs. (S)-ibuprofen (IBP), a non-steroidal anti-inflammatory agent, has been used for muscle healing and to treat venous leg ulcers, but its effect in skin wound healing has not been thoroughly studied thus far. Herein, IBP-β-cyclodextrins carriers were designed to customise the release profile of IBP from poly(vinyl alcohol)/chitosan (PVA/CS) dressings in order to promote a faster skin regeneration...
March 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28035668/ice-and-anti-nucleating-activities-of-an-ice-binding-protein-from-the-annual-grass-brachypodium-distachyon
#13
Melissa Bredow, Heather E Tomalty, Lindsay Smith, Virginia K Walker
Plants exposed to sub-zero temperatures face unique challenges that threaten their survival. The growth of ice crystals in the extracellular space can cause cellular dehydration, plasma membrane rupture, and eventual cell death. Additionally, some pathogenic bacteria cause tissue damage by initiating ice crystal growth at high sub-zero temperatures through the use of ice nucleating proteins (INPs), presumably to access nutrients from lysed cells. An annual species of brome grass, Brachypodium distachyon (Bd), produces an ice-binding protein (IBP) that shapes ice with a modest depression of the freezing point (~0...
December 30, 2016: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28012225/drivers-of-genetic-differentiation-in-a-generalist-insect-pollinated-herb-across-spatial-scales
#14
A J Muñoz-Pajares, C García, M Abdelaziz, J Bosch, F Perfectti, J M Gómez
The isolation-by-distance model (IBD) predicts that genetic differentiation among populations increases with geographic distance. Yet, empirical studies show that a variety of ecological, topographic and historical factors may override the effect of geographic distance on genetic variation. This may particularly apply to species with narrow but highly heterogeneous distribution ranges, such as those occurring along elevational gradients. Using nine SSR markers, we study the genetic differentiation of the montane pollination-generalist herb, Erysimum mediohispanicum...
December 24, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27987298/the-role-of-civil-society-in-strengthening-intercultural-maternal-health-care-in-local-health-facilities-puno-peru
#15
Jeannie Samuel
BACKGROUND AND OBJECTIVE: Peru's Ministry of Health has made efforts to increase the cultural inclusiveness of maternal health services. In 2005, the Ministry adopted an intercultural birthing policy (IBP) that authorizes and encourages the use of culturally acceptable birthing practices in government-run health facilities. However, studies suggest that indigenous women may receive inconsistent benefits from these kinds of policies. This article examines whether a grassroots accountability initiative based on citizen monitoring of local health facilities by indigenous women can help to promote the objectives of the IBP and improve intercultural maternal health care...
2016: Global Health Action
https://www.readbyqxmd.com/read/27973620/a-genome-wide-snp-linkage-analysis-suggests-a-susceptibility-locus-on-6p21-for-ankylosing-spondylitis-and-inflammatory-back-pain-trait
#16
Yanli Zhang, Zetao Liao, Qiujing Wei, Yunfeng Pan, Xinwei Wang, Shuangyan Cao, Zishi Guo, Yuqiong Wu, Ju Rong, Ou Jin, Manlong Xu, Zhiming Lin, Jieruo Gu
OBJECTIVES: To screen susceptibility loci for ankylosing spondylitis (AS) using an affected-only linkage analysis based on high-density single nucleotide polymorphisms (SNPs) in a genome-wide manner. PATIENTS AND METHODS: AS patients from ten families with Cantonese origin of China were enrolled in the study. Blood samples were genotyped using genomic DNA derived from peripheral blood leukocytes by Illumina HumanHap 610-Quad SNP Chip. Genotype data were generated using the Illumina BeadStudio 3...
2016: PloS One
https://www.readbyqxmd.com/read/27969016/ineffective-breathing-pattern-in-cardiac-postoperative-patients-diagnostic-accuracy-study
#17
Vanessa Emille Carvalho de Sousa, Lívia Maia Pascoal, Ranielly Vidal do Nascimento, Talita Ferreira Oliveira de Matos, Beatriz Amorim Beltrão, Viviane Martins da Silva, Marcos Venícios de Oliveira Lopes
PURPOSE: The aim of this study was to analyze the accuracy of the defining characteristics of ineffective breathing pattern (IBP) in postoperative cardiac patients. METHODS: A diagnostic accuracy study was performed with 98 patients. Measures of sensitivity, specificity, predictive values, likelihood ratios, diagnostic odds ratio, and area under the ROC curve were calculated. RESULTS: IBP was present in 23.5% of the patients. Alterations in depth of breathing (sensitivity 96%, negative likelihood ratio 0...
November 2016: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/27959937/knockdown-of-ice-binding-proteins-in-brachypodium-distachyon-demonstrates-their-role-in-freeze-protection
#18
Melissa Bredow, Barbara Vanderbeld, Virginia K Walker
Sub-zero temperatures pose a major threat to the survival of cold-climate perennials. Some of these freeze-tolerant plants produce ice-binding proteins (IBPs) that offer frost protection by restricting ice crystal growth and preventing expansion-induced lysis of the plasma membranes. Despite the extensive in vitro characterization of such proteins, the importance of IBPs in the freezing stress response has not been investigated. Using the freeze-tolerant grass and model crop, Brachypodium distachyon, we characterized putative IBPs (BdIRIs) and generated the first 'IBP-knockdowns'...
2016: PloS One
https://www.readbyqxmd.com/read/27932923/india-biodiversity-portal-an-integrated-interactive-and-participatory-biodiversity-informatics-platform
#19
Thomas Vattakaven, Rohit M George, Dhandapani Balasubramanian, Maxime Réjou-Méchain, Gowrappan Muthusankar, Brahmasamudra Ranganna Ramesh, R Prabhakar
BACKGROUND: This paper describes a growing biodiversity platform, launched in 2008, which organizes knowledge on the biodiversity of India. The main objective and originality of the India Biodiversity Portal (IBP) is to aggregate curated biodiversity data of different kinds (e.g. distribution maps, temporal distribution or life history) in an integrated platform where amateurs and experts can easily interact. NEW INFORMATION: Since its launch, the platform has seen an exceptional increase in both user activity and biodiversity data...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27881992/molecular-mapping-and-qtl-for-expression-profiles-of-flavonoid-genes-in-brassica-napus
#20
Cunmin Qu, Huiyan Zhao, Fuyou Fu, Kai Zhang, Jianglian Yuan, Liezhao Liu, Rui Wang, Xinfu Xu, Kun Lu, Jia-Na Li
Flavonoids are secondary metabolites that are extensively distributed in the plant kingdom and contribute to seed coat color formation in rapeseed. To decipher the genetic networks underlying flavonoid biosynthesis in rapeseed, we constructed a high-density genetic linkage map with 1089 polymorphic loci (including 464 SSR loci, 97 RAPD loci, 451 SRAP loci, and 75 IBP loci) using recombinant inbred lines (RILs). The map consists of 19 linkage groups and covers 2775 cM of the B. napus genome with an average distance of 2...
2016: Frontiers in Plant Science
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