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https://www.readbyqxmd.com/read/27906387/hierarchically-porous-materials-synthesis-strategies-and-structure-design
#1
REVIEW
Xiao-Yu Yang, Li-Hua Chen, Yu Li, Joanna Claire Rooke, Clément Sanchez, Bao-Lian Su
Owing to their immense potential in energy conversion and storage, catalysis, photocatalysis, adsorption, separation and life science applications, significant interest has been devoted to the design and synthesis of hierarchically porous materials. The hierarchy of materials on porosity, structural, morphological, and component levels is key for high performance in all kinds of applications. Synthesis and applications of hierarchically structured porous materials have become a rapidly evolving field of current interest...
December 1, 2016: Chemical Society Reviews
https://www.readbyqxmd.com/read/27906311/colored-point-spread-function-engineering-for-parallel-confocal-microscopy
#2
Alexander Jesacher, Stefan Bernet, Monika Ritsch-Marte
Using the color selectivity of a spatial light modulator (SLM) for both, tailoring the excitation beam at one wavelength, and multiplexing the image at the red-shifted fluorescence wavelength, it is possible to parallelize confocal microscopy, i.e. to simultaneously detect an axial stack (z-stack) of a sample. For this purpose, two diffractive patterns, one steering the excitation light, and the other manipulating the emission light, are combined within the same area of the SLM, which acts as a pure phase modulator...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906303/higher-order-surface-plasmon-contributions-to-passive-and-active-plasmonic-interferometry
#3
Dongfang Li, Jing Feng, Domenico Pacifici
We compare the intensity modulation of passive light transmission and active fluorescence emission in planar plasmonic interferometers consisting of a nano-scale hole flanked by circular grooves etched in a silver film. Discrete fast Fourier transform applied to plasmonic interferograms - i.e., optical interferograms obtained by varying the propagation phase of surface plasmon polaritons (SPPs) - reveals higher-order interference effects that can be enhanced by optimizing in-plane SPP scattering and reflection...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906264/optimal-phase-element-for-generating-a-perfect-optical-vortex
#4
Victor V Kotlyar, Alexey A Kovalev, Alexey P Porfirev
We derived exact analytical relationships to describe the complex amplitude of a perfect optical vortex generated by means of three different optical elements, namely, (i) an amplitude-phase element with a transmission function proportional to a Bessel function, (ii) an optimal phase element with a transmission equal to the sign function of a Bessel function, and (iii) a spiral axicon. The doughnut intensity was shown to be highest when using an optimal phase element. The spiral-axicon-aided diffraction ring was found to be twice as wide as when generated using two other elements...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906258/optical-cryptosystem-based-on-single-pixel-encoding-using-the-modified-gerchberg-saxton-algorithm-with-a-cascaded-structure
#5
Wen Chen
In this paper, an optical cryptosystem is developed based on single-pixel encoding using the modified Gerchberg-Saxton algorithm with a cascaded structure. A series of random intensity-only patterns are pre-generated as principal security keys, and phase-only masks for optical encoding and decoding are generated by the modified Gerchberg-Saxton algorithm with a cascaded structure. Subsequently, a series of 1D intensity points, i.e., ciphertexts, are recorded by a single-pixel detector, which may provide a potential for establishing low-cost and compact security systems...
December 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27906209/magnetization-induced-effects-in-second-harmonic-generation-under-the-lattice-plasmon-resonance-excitation
#6
I A Kolmychek, A N Shaimanov, A V Baryshev, T V Murzina
We present an experimental study of optical second harmonic generation (SHG) from arrays of nanostructures exhibiting collective plasmon resonances in the visible spectral range. Gold nanoparticles with the lateral diameter of 100 nm are packed in a square lattice with the period of 400 nm and are covered by a 90 nm thick iron garnet layer. We show an enhancement of SHG in the spectral vicinity of the lattice surface plasmon resonance. It is demonstrated that application of the external DC magnetic field results in a spectral shift of the SHG maximum up to 5 nm, accompanied by a pronounced phase modulation of the second harmonic wave...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27906070/subretinal-adipose-tissue-derived-mesenchymal-stem-cell-implantation-in-advanced-stage-retinitis-pigmentosa-a-phase-i-clinical-safety-study
#7
Ayse Oner, Z Burcin Gonen, Neslihan Sinim, Mustafa Cetin, Yusuf Ozkul
BACKGROUND: This prospective clinical case series aimed to investigate the safety of subretinal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in advanced stage retinitis pigmentosa (RP). METHODS: This study included 11 patients with end-stage RP who received subretinal implantation of ADMSCs. All patients had a total visual field defect and five of them only had light perception. The best corrected visual acuity (BCVA) in the study was 20/2000...
December 1, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27906037/integrated-therapy-for-hiv-and-cryptococcosis
#8
REVIEW
Sirawat Srichatrapimuk, Somnuek Sungkanuparph
Cryptococcosis has been one of the most common opportunistic infections and causes of mortality among HIV-infected patients, especially in resource-limited countries. Cryptococcal meningitis is the most common form of cryptococcosis. Laboratory diagnosis of cryptococcosis includes direct microscopic examination, isolation of Cryptococcus from a clinical specimen, and detection of cryptococcal antigen. Without appropriate treatment, cryptococcosis is fatal. Early diagnosis and treatment is the key to treatment success...
November 29, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905989/the-histone-deacetylase-inhibitor-sodium-butyrate-exhibits-neuroprotective-effects-for-ischemic-stroke-in-middle-aged-female-rats
#9
Min Jung Park, Farida Sohrabji
BACKGROUND: Sodium butyrate (NaB) is a histone deacetylase (HDAC) inhibitor exhibiting anti-inflammatory and neuroprotective effects in a rat ischemic model of stroke as well as a myocardial ischemia model. Although clinical evidence shows that older women are at higher risk for stroke occurrence and greater stroke severity, no studies have evaluated the effectiveness of NaB either in females or in older animals. METHODS: To determine the effects of NaB on stroke in older females, acyclic middle-aged Sprague-Dawley female rats (9-11 months old, constant diestrus) were subject to middle cerebral artery occlusion (MCAo) by intracerebral injection of recombinant endothelin-1...
December 1, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27905954/measuring-and-tracking-obesity-inequality-in-the-united-states-evidence-from-nhanes-1971-2014
#10
Tae-Young Pak, Susana Ferreira, Gregory Colson
BACKGROUND: Because people care about their weight relative to peers and society, obesity inequality plays a role in explaining obesity incidence and the impacts of being obese on subjective well-being. While the increase in obesity prevalence and mean body mass index (BMI) is well documented, the measurement of distributional changes and corresponding obesity inequality is yet to be fully explored. METHODS: The present study analyzed BMI data for adults aged 20 to 74 from the National Health and Nutritional Examination Survey (NHANES) I (1971-1974), II (1976-1980), III (1988-1994), and continuous NHANES (1999-2014)...
April 4, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905841/cell-delivered-entry-inhibitors-for-hiv-1-ccr5-downregulation-and-blocking-virus-membrane-fusion-in-defending-the-host-cell-population
#11
Geoff Symonds, Jeffrey S Bartlett, Hans-Peter Kiem, Marlene Tsie, Louis Breton
HIV-1 infection requires the presence of the CD4 receptor on the target cell surface and a coreceptor, predominantly CC-chemokine receptor 5 (CCR5). It has been shown that individuals who are homozygous for a defective CCR5 gene are protected from HIV-1 infection. A novel self-inactivating lentiviral vector LVsh5/C46 (Cal-1) has been engineered to block HIV-1 infection with two viral entry inhibitors, conferring resistance to HIV-1 infection from both CCR5 and CXCR4 tropic strains. Cal-1 encodes a short hairpin RNA (sh5) to downregulate CCR5 and C46, an HIV-1 fusion inhibitor...
December 2016: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/27905678/a-phase-i-ii-trial-of-at9283-a-selective-inhibitor-of-aurora-kinase-in-children-with-relapsed-or-refractory-acute-leukemia-challenges-to-run-early-phase-clinical-trials-for-children-with-leukemia
#12
B Vormoor, G J Veal, M J Griffin, A V Boddy, J Irving, L Minto, M Case, U Banerji, K E Swales, J R Tall, A S Moore, M Toguchi, G Acton, K Dyer, C Schwab, C J Harrison, J D Grainger, D Lancaster, P Kearns, D Hargrave, J Vormoor
Aurora kinases regulate mitosis and are commonly overexpressed in leukemia. This phase I/IIa study of AT9283, a multikinase inhibitor, was designed to identify maximal tolerated doses, safety, pharmacokinetics, and pharmacodynamic activity in children with relapsed/refractory acute leukemia. The trial suffered from poor recruitment and terminated early, therefore failing to identify its primary endpoints. AT9283 caused tolerable toxicity, but failed to show clinical responses. Future trials should be based on robust preclinical data that provide an indication of which patients may benefit from the experimental agent, and recruitment should be improved through international collaborations and early combination with established treatment strategies...
December 1, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27905662/client-related-factors-associated-with-a-less-than-good-experience-of-midwifery-care-during-childbirth-in-the-netherlands
#13
Carien I Baas, Therese A Wiegers, T Paul de Cock, Jan Jaap H M Erwich, Evelien R Spelten, Michiel R de Boer, Eileen K Hutton
BACKGROUND: A "less than good" experience during childbirth can affect a mother's early interaction with her child and may significantly influence a woman's emotional well-being. In this study, we focus on clients who experienced midwifery care provided during childbirth as "less than good" care. The aim of this study was to understand the relationship between client-related factors and the experience of midwifery care during childbirth to improve this care. METHODS: This study was part of the "DELIVER study" where mothers report on the care they received...
December 1, 2016: Birth
https://www.readbyqxmd.com/read/27905543/rapid-functional-cardiac-imaging-after-gadolinium-injection-evaluation-of-a-highly-accelerated-sequence-with-sparse-data-sampling-and-iterative-reconstruction
#14
Johannes Budjan, Holger Haubenreisser, Thomas Henzler, Sonja Sudarski, Michaela Schmidt, Christina Doesch, Ibrahim Akin, Martin Borggrefe, Nadja M Meßner, Stefan O Schoenberg, Ulrike I Attenberger, Theano Papavassiliu
To generate a patient-friendly, time-efficient cardiac MRI examination protocol, a highly accelerated real-time CINE MR sequence (SSIR) was acquired in the idle time in between contrast injection and late gadolinium enhancement phase. 20 consecutive patients underwent a cardiac MRI examination including a multi-breath-hold sequence as gold standard (Ref) as well as SSIR sequences with (SSIR-BH) and without breath-hold (SSIR-nonBH). SSIR sequences were acquired 4 minutes after gadolinium injection. Right- (RV) and left-ventricular (LV) volumetric functional parameters were evaluated and compared between Ref and SSIR sequences...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27905155/optimising-qualitative-longitudinal-analysis-insights-from-a-study-of-traumatic-brain-injury-recovery-and-adaptation
#15
Joanna K Fadyl, Alexis Channon, Alice Theadom, Kathryn M McPherson
Knowledge about aspects that influence recovery and adaptation in the postacute phase of disabling health events is key to understanding how best to provide appropriate rehabilitation and health services. Qualitative longitudinal research makes it possible to look for patterns, key time points and critical moments that could be vital for interventions and supports. However, strategies that support robust data management and analysis for longitudinal qualitative research in health-care are not well documented in the literature...
November 30, 2016: Nursing Inquiry
https://www.readbyqxmd.com/read/27904937/separation-of-cyclic-lipopeptide-puwainaphycins-from-cyanobacteria-by-countercurrent-chromatography-combined-with-polymeric-resins-and-hplc
#16
José Cheel, Petra Urajová, Jan Hájek, Pavel Hrouzek, Marek Kuzma, Elodie Bouju, Karine Faure, Jiří Kopecký
Puwainaphycins are a recently described group of β-amino fatty acid cyclic lipopeptides of cyanobacterial origin that possess interesting biological activities. Therefore, the development of an efficient method for their isolation from natural sources is necessary. Following the consecutive adsorption of the crude extract on Amberlite XAD-16 and XAD-7 resins, countercurrent chromatography (CCC) was applied to separate seven puwainaphycin variants from a soil cyanobacterium (Cylindrospermum alatosporum CCALA 988)...
November 30, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27904905/idarucizumab-does-not-have-procoagulant-effects-assessment-of-thrombosis-biomarkers-in-healthy-volunteers
#17
Michael Schmohl, Stephan Glund, Akiko Harada, Susumu Imazu, Marina De Smet, Viktoria Moschetti, Steven Ramael, Ippei Ikushima, Fredrik Grünenfelder, Paul Reilly, Joachim Stangier
Idarucizumab, a humanised monoclonal antibody fragment, binds dabigatran with high affinity and immediately, completely and sustainably reverses dabigatran-induced changes on blood coagulation. The present analysis focuses on the evaluation of potential procoagulant properties of idarucizumab when administered in the absence of dabigatran. As part of two Phase I studies conducted in healthy Caucasian and Japanese male volunteers, the effect of idarucizumab (8 g as a 1-hour [h] infusion and 4 g as a 5-minute [min] infusion) and placebo on calibrated automated thrombography (CAT) was assessed using platelet-poor plasma samples...
December 1, 2016: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/27904802/abundance-and-physiology-of-dominant-soft-corals-linked-to-water-quality-in-jakarta-bay-indonesia
#18
Gunilla Baum, Indra Januar, Sebastian C A Ferse, Christian Wild, Andreas Kunzmann
Declining water quality is one of the main reasons of coral reef degradation in the Thousand Islands off the megacity Jakarta, Indonesia. Shifts in benthic community composition to higher soft coral abundances have been reported for many degraded reefs throughout the Indo-Pacific. However, it is not clear to what extent soft coral abundance and physiology are influenced by water quality. In this study, live benthic cover and water quality (i.e. dissolved inorganic nutrients (DIN), turbidity (NTU), and sedimentation) were assessed at three sites (< 20 km north of Jakarta) in Jakarta Bay (JB) and five sites along the outer Thousand Islands (20-60 km north of Jakarta)...
2016: PeerJ
https://www.readbyqxmd.com/read/27904762/activin-receptor-like-kinases-a-diverse-family-playing-an-important-role-in-cancer
#19
REVIEW
Holli A Loomans, Claudia D Andl
The role and function of the members of the TGFβ superfamily has been a substantial area of research focus for the last several decades. During that time, it has become apparent that aberrations in TGFβ family signaling, whether through the BMP, Activin, or TGFβ arms of the pathway, can result in tumorigenesis or contribute to its progression. Downstream signaling regulates cellular growth under normal physiological conditions yet induces diverse processes during carcinogenesis, ranging from epithelial- to-mesenchymal transition to cell migration and invasion to angiogenesis...
2016: American Journal of Cancer Research
https://www.readbyqxmd.com/read/27904170/twenty-five-year-old-woman-with-bilateral-borderline-ovarian-tumour-desiring-to-preserve-fertility-case-report-and-literature-review-on-the-current-state-of-fertility-preservation-in-women-with-borderline-ovarian-tumours
#20
S Findeklee, L Lotz, K Heusinger, I Hoffmann, R Dittrich, M W Beckmann
Borderline ovarian tumours are semimalignant tumours occurring unilaterally or bilaterally with a peak incidence among women of reproductive age. Since the affected women often wish to preserve fertility, particular precautions must be taken when counselling the patient and obtaining consent prior to planning an individual treatment. Options for preserving fertility include an organ-sparing surgical procedure and cryopreservation of oocytes and/or ovarian tissue. In this article, we report on a 25-year-old patient with a bilateral seromucinous borderline tumour who desired all fertility-preserving options...
November 2016: Geburtshilfe und Frauenheilkunde
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