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case report of pseudomonas keratitis

Dinesh Subedi, Ajay Kumar Vijay, Mark Willcox
Treatment of Pseudomonas aeruginosa eye infections often becomes a challenge due to the ability of this bacterium to be resistant to antibiotics via intrinsic and acquired mechanisms. Transfer of resistance due to interchangeable genetic elements is an important mechanism for the rapid transfer of antibiotic resistance in this pathogen. As a result, drug-resistant strains are becoming increasingly prevalent worldwide. This review systematically analyses data from recent publications to describe the global prevalence and antibiotic sensitivity of ocular P...
October 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Ka Wai Kam, Wing Yung, Gabriel Ka Hin Li, Li Jia Chen, Alvin L Young
PURPOSE: Myopia is a prevalent condition among Asians. Orthokeratology lens has gained popularity as a method of myopia control. This systematic review is to summarize the clinical profile of infectious keratitis in association with orthokeratology lens wear. METHODS: We searched in the PubMed and EMBASE for articles adopting the search strategy "(orthokeratology lens OR orthokeratology) AND (bacterial eye infection OR keratitis OR cornea ulcer OR microbial keratitis OR bacterial keratitis)", from the start date of the databases to August 23, 2016...
December 2017: Infection
Julia Dutra Rossetto, Kara M Cavuoto, Carla J Osigian, Ta Chen Peter Chang, Darlene Miller, Hilda Capo, Oriel Spierer
BACKGROUND/AIMS: Corneal ulcers can result in severe visual impairment in children. The recent trends of paediatric microbial ulcerative keratitis in the USA are unknown. The purpose of this study is to report the risk factors, microbiological profile and treatment outcomes of paediatric microbial keratitis in South Florida. METHODS: A university-based tertiary eye care centre retrospective case series between 1992 and 2015. Medical records of 107 paediatric patients (age <18 years) with the diagnosis of microbial ulcerative keratitis were analysed...
November 2017: British Journal of Ophthalmology
Mingwu Wang, Whitney A Smith, Joshua K Duncan, Joseph M Miller
PURPOSE: Despite following standard treatment, Pseudomonas keratitis can continue to progress and result in loss of vision or of the eye. Our cases demonstrate that the Morgan Lens can be an effective topical antibiotic delivery vehicle in advanced keratitis. METHODS: Two patients (3 eyes) with Pseudomonas keratitis were included in this report after failing to respond to intense inpatient topical treatment. Because loss of the eyes was imminent, the Morgan Lenses were used for continuous lavage with ceftazidime (50 mg/mL), in conjunction with other conventional treatment...
May 2017: Cornea
Manali Hazarika, Vijaya Pai H, Vinay Khanna, Harish Reddy, Kriti Tilak, Kiran Chawla
PURPOSE: To report a rare case of polymicrobial keratitis due to Balantidium coli and gram-negative bacteria, Pseudomonas aeruginosa and Klebsiella pneumoniae, in a soft contact lens (CL) wearer. METHODS: We report a case of CL-related keratitis due to B. coli, P. aeruginosa, and K. pneumoniae. RESULTS: The culture of the corneal scrapings, the CL cleaning solution, and the CL revealed the growth of a rare ciliated parasite, B. coli, along with gram-negative bacteria, namely, P...
December 2016: Cornea
Mehrdad Mohammadpour, Fatemeh Alsadat Sabet
PURPOSE: To report the anatomical and visual outcomes of double layered amniotic membrane transplantation (AMT) in eyes with advanced Pseudomonas keratitis leading to Descemetocele formation. METHODS: This prospective interventional case series included 6 eyes of 6 female patients with pseudomonas keratitis caused by contact lens-induced infection who underwent double layered AMT. Surgery was performed after the ulcers were found to be poorly responsive to antibiotics, and severe thinning or Descemetocele had developed...
January 2016: Journal of Ophthalmic & Vision Research
Prajna Lalitha, Geetha Manoharan, Rajaram Karpagam, Namperumalsamy V Prajna, Muthiah Srinivasan, Jeena Mascarenhas, Manoranjan Das, Travis C Porco, Thomas M Lietman, Vicky Cevallos, Jeremy D Keenan
AIMS: To report trends in antibiotic resistance in cases of bacterial keratitis from a large eye hospital in South India. METHODS: In this retrospective cross-sectional study, the microbiology laboratory records of patients with infectious keratitis diagnosed at an eye hospital in South India from 2002 to 2013 were reviewed to determine the proportion with antibiotic non-susceptibility. RESULTS: 3685 bacterial isolates had susceptibility testing performed over the 12-year period...
February 2017: British Journal of Ophthalmology
Thiago Dos Santos Gomes, Angela Magnet, Fernando Izquierdo, Lucianna Vaccaro, Fernando Redondo, Sara Bueno, Maria Luisa Sánchez, Santiago Angulo, Soledad Fenoy, Carolina Hurtado, Carmen Del Aguila
PURPOSE: Acanthamoeba keratitis (AK) is a painful and potentially blinding corneal infection caused by Acanthamoeba spp. In Madrid, environmental studies have demonstrated a high presence of these free-living amoebae in tap water. Since most of AK cases occur in contact lenses (CL) wearers with inadequate hygiene habits, the presence of Acanthamoeba in discarded CL has been studied and compared with other common etiological agents of keratitis, such as Pseudomonas aeruginosa and Staphylococcus aureus...
2016: PloS One
Gelareh S Noureddin, Sachiko Sasaki, Andrea L Butler, Peter Tilley, Diane Roscoe, Christopher J Lyons, Simon P Holland, Sonia N Yeung
OBJECTIVE: To report the clinical and microbiological profiles of paediatric patients with infectious keratitis in Vancouver, Canada. DESIGN: In this observational case series, the microbiology results and medical records of 17 eyes with microbial keratitis in 16 children aged 17 years or younger were retrospectively reviewed. These patients had undergone corneal scraping between May 2006 and April 2011 at BC Children's Hospital or Vancouver General Hospital Eye Care Centre in Vancouver, British Columbia, Canada...
December 2016: British Journal of Ophthalmology
Dimitri Roels, Sophie De Craene, Philippe Kestelyn
The presence of keratoneuritis in a radial pattern is considered to be a virtually pathognomonic sign of Acanthamoeba keratitis. We report a case of a massive keratoneuritis as a presenting sign in Pseudomonas keratitis in a contact lens wearer, thereby further challenging this concept.
February 2017: International Ophthalmology
Kaevalin Lekhanont, Passara Jongkhajornpong, Pichaya Chuephanich, Tsutomu Inatomi, Shigeru Kinoshita
PURPOSE: To report the outcomes of Boston type 1 keratoprosthesis in the management of advanced gelatinous drop-like corneal dystrophy (GDLD). METHODS: A retrospective, noncomparative, interventional case series was conducted at Ramathibodi Hospital, Bangkok, Thailand. Four eyes of three siblings with molecularly and histologically confirmed GDLD from a Thai family underwent an uneventful Boston type 1 keratoprosthesis implantation for visual rehabilitation. Clinical data were obtained from a review of the medical records...
June 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Hesam Hedayati, Mahboubeh Ghaderpanah, Seyed Ahmad Rasoulinejad, Mohammad Montazeri
Introduction. In recent years, the number of contact lens wearers has dramatically increased in Iran, particularly in youngsters. The purpose of current study was to assess the clinical presentation and antibiotic susceptibility of contact lens related microbial keratitis in Ahvaz, southwest of Iran. Methodology. A cross-sectional investigation of 26 patients (33 eyes) with contact lens induced corneal ulcers who were admitted to Imam Khomeini Hospital, Ahwaz City, from June 2012 to June 2013 was done. In order to study microbial culture and susceptibility of corneal ulcers, all of them were scraped...
2015: Journal of Pathogens
Seyed Ahmad Rasoulinejad, Mahmoud Sadeghi, Mohammad Montazeri, Hesam Hedayati Goudarzi, Mahmood Montazeri, Nadali Akbarian
INTRODUCTION: Microbial keratitis is an infective process of the cornea with a potentially and serious visual impairments. Contact lenses are a major cause of microbial keratitis in the developed countries especially among young people. Therefore, the purpose of the present study was to evaluate the frequency and microbiological characteristic of CLK in patients referred to the emergency department (ED) of teaching hospitals, Babol, Iran. METHODS: This is a cross-sectional study of all patients with contact lens induced corneal ulcers admitted to the teaching hospitals of Babol, Iran, from 2011- 2013...
2014: Emergency (Tehran, Iran)
Jayesh Vazirani, Siva Wurity, Md Hasnat Ali
PURPOSE: To identify risk factors for multidrug-resistant Pseudomonas aeruginosa (MDR-PA) keratitis and to report clinical characteristics and outcomes of this infection. DESIGN: Retrospective, case-control study. PARTICIPANTS: Ninety episodes of P. aeruginosa keratitis from a tertiary care eye institution from 2007 through 2014 were identified. Episodes of MDR-PA keratitis were taken as cases. Episodes of drug-sensitive P. aeruginosa keratitis during the same period were taken as controls...
October 2015: Ophthalmology
Bibhudutta Rautaraya, Savitri Sharma, Md Hasnat Ali, Sarita Kar, Sujata Das, Srikant K Sahu
PURPOSE: To report the clinical and microbiological characteristics and treatment outcome of bacterial keratitis at a tertiary eye care center in eastern India. DESIGN: Retrospective analysis of medical and microbiology records. METHODS: All patients had undergone complete clinical and microbiological evaluation for microbial keratitis. Patients with laboratory-proven bacterial keratitis were included in the study. RESULTS: Between July 2006 and December 2010, 1417 microbial keratitis was clinically diagnosed in the patients...
May 2014: Asia-Pacific Journal of Ophthalmology
Rebika Dhiman, Archita Singh, Radhika Tandon, M Vanathi
UNLABELLED: To report a case of bandage contact lens induced infectious keratitis caused by Pseudomonas aeruginosa following DSAEK. CASE REPORT: A 56-year-old female who underwent DSAEK at our institute for pseudophakic bullous keratopathy, developed contact lens induced keratitis in the fifth post operative week. Best corrected visual acuity (BCVA) reduced to perception of light in the left eye. Slit lamp examination revealed an epithelial ulcer measuring 4.7mm×6mm with surrounding infiltrates in the anterior stroma with hypopyon...
October 2015: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Julio C Hernandez-Camarena, Enrique O Graue-Hernandez, Mariana Ortiz-Casas, Arturo Ramirez-Miranda, Alejandro Navas, Lucero Pedro-Aguilar, Nadia L Lopez-Espinosa, Carolina Gaona-Juarez, Luis A Bautista-Hernandez, Victor M Bautista-de Lucio
PURPOSE: To report the distribution and trends in microbiological and antibiotic sensitivity patterns of infectious keratitis in a 10-year period at a reference center in Mexico City. METHODS: In this retrospective observational case series, samples were obtained from corneas with a diagnosis of infectious keratitis from January 2002 to December 2011 at the Institute of Ophthalmology "Conde de Valenciana" in Mexico City. Results of cultures, stains, and specific sensitivity/resistance antibiograms for each microorganism were analyzed...
July 2015: Cornea
Jung Lo, Ming-Tse Kuo, Chun-Chih Chien, Shin-Ling Tseng, Yu-Hsuan Lai, Po-Chiung Fang
OBJECTIVE: To assess the bioburden in an orthokeratology contact lens (OK) care system (defined by microbial identification from OK case fluid) and to identify the risk factors causing high bioburden for pediatric OK wearers in southern Taiwan. METHODS: A prospective study for the investigation of bioburden in the OK care system was performed in a tertiary medical center in southern Taiwan. Microbial isolates from the case fluids soaking OKs were analyzed, and pathogenicity was determined...
January 2016: Eye & Contact Lens
Jiaxu Hong, Qihua Le, Sophie X Deng, Wenjun Cao, Jianjiang Xu
BACKGROUND: To report a case of non-typical Pseudomonas aeruginosa keratitis that was misdiagnosed as fungal keratitis by in vivo confocal microscopy. CASE PRESENTATION: A 37-year-old Chinese woman presented with a 2-week history of increasing pain and redness of the right eye. She was started on hourly topical fortified tobramycin and levofloxacin by the referring doctor without improvement. She denied any improvement of her symptoms and signs. On examination, she had a large central corneal ulcer extending to the peripheral cornea...
2014: BMC Research Notes
A Abbouda, I Abicca, J L Alió
AIM: To describe the infectious complications and the group of pathogens involved in the infection following corneal crosslinking, the visual outcome, and the treatment proposed. METHODS: A Medline (National Library of Medicine, Bethesda, MD, USA) search from October 2000 to October 2013 was performed to identify all articles describing infectious keratitis following corneal crosslinking treatment. Nineteen articles were selected. Ten articles reported infectious complications of corneal crosslinking treatment were included...
2016: Seminars in Ophthalmology
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